Keywords: عصاره سیگار سیگار; Airway inflammation; Airway remodeling; Anti-muscarinic drug; Cholinergic regulation; Non-neuronal ACh; ACh; acetylcholine; ASM; airway smooth muscle; cAMP; cyclic adenosine monophosphate; ChAT; choline acetyltransferase; CHT1; high-affinity choline trans
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Keywords: عصاره سیگار سیگار; BALF; bronchoalveolar lavage fluid; COPD; chronic obstructive pulmonary disease; CS; cigarette smoke; CSE; cigarette smoke extract; LAMA; long-acting muscarinic receptor antagonists; MIP-2; macrophage inflammatory protein-2; MAPK; mitogen-activated protei
Keywords: عصاره سیگار سیگار; Cigarette smoke extract; Ovarian cancer cells; Cell cycle; Apoptosis; TUNEL; ROS; Oxidative stress; ER-stress;
Keywords: عصاره سیگار سیگار; 3D; three-dimensional; AEGM; Airway Epithelial Cell Growth Medium; ALI; air-liquid interface; CS; cigarette smoke; CSE; cigarette smoke extract; COPD; chronic obstructive pulmonary disease; CYP; cytochrome P450; FBS; fetal bovine serum; HBECs; human bronc
Keywords: عصاره سیگار سیگار; BALs; Broncho Alveolar Lavages; CSE; Cigarette Smoke Extract; COPD; Chronic Obstructive Pulmonary Disease; EVs; Extracellular Vesicles; EZH2; Enhancer of zeste homolog 2; HMGA2; High-mobility group AT-hook 2; IARC; International Agency For Research On Can
Keywords: عصاره سیگار سیگار; ARE; Anti-Oxidant Response Element; BBB; Blood-Brain Barrier; CS; Cigarette Smoke; CSE; Cigarette Smoke Extract; 2DM; Type 2 Diabetes Mellitus; FJC; Fluoro-Jade C; FTC; Federal Trade Control; ISO; International Organization for Standardization; MF; Metfor
Keywords: عصاره سیگار سیگار; Cigarette smoke extract; Placental cells; Cell cycle; Metastasis; Human chorionic gonadotropin beta subunit;
Keywords: عصاره سیگار سیگار; Cigarette smoke extract; Endothelial dysfunction; Endothelial cells; Shear stress and laminar flow; NRF2; Monocyte adhesion;
Keywords: عصاره سیگار سیگار; Alcohol; Smoking; ER Stress; Pancreas; A; alcohol diet; AL; alcohol diet + LPS; ALS; alcohol diet + LPS + smoking; AS; alcohol diet + smoking; Acro; acrolein; AhR; Aryl hydrocarbon receptor; BIAM; biotin-conjugated iodoacetamide (N-(biotinoyl)-N-(iodo
Keywords: عصاره سیگار سیگار; AECs; airway epithelial cells; AEGM; airway epithelial growth media; CSE; cigarette smoke extract; EGFR; epidermal growth factor receptor; NECs; nasal epithelial cells; CSE; Inflammation; Cytokine; Airway; Epithelial; Bronchial; Nasal; Cells; EGFR; IL-8;
Keywords: عصاره سیگار سیگار; Cigarette smoke extract; Ovarian cancer cells; Cell cycle; Metastasis; Epithelial-mesenchymal transition;
Keywords: عصاره سیگار سیگار; Cigarette smoke extract; Antigen presenting cell; Gene array; Eclipse; Dendritic cell;
Keywords: عصاره سیگار سیگار; BIS I; 2-[1-(3-dimethylaminopropyl)-1H-indol-3-yl]-3-(1H-indol-3-yl)-maleimide; CSE; cigarette smoke extract; CPO; 2-cyclopenten-1-one; DMEM; Dulbecco's modified Eagle's medium; DPI; diphenyleneiodonium chloride; ESI; electrospray ionization; MTS; 3-(4,5-
Protective effect of methylallyl sulfone in the development of cigarette smoke extract-induced apoptosis in rats and HFL-1 cells
Keywords: عصاره سیگار سیگار; Garlic organosulfur compounds; Cigarette smoke extract; Apoptosis; Oxidative stress;
Cigarette smoke extract acts directly on CD4 T cells to enhance Th1 polarization and reduce memory potential
Keywords: عصاره سیگار سیگار; 7-AAD; 7-Aminoactinomycin D; APC; antigen presenting cell; CFSE; carboxyfluorescein succinimidyl ester; CSE; cigarette smoke extract; IFNγ; interferon gamma; T-bet; T-box transcription factor TBX21; Th1; T helper type 1; TNF; tumor necrosis factor alpha;
Exosomes as a liquid biopsy for lung cancer
Keywords: عصاره سیگار سیگار; Alix; ALG 2 interacting protein X; ALK; anaplastic lymphoma kinase; AREG; Amphiregulin; Atg2; autophagy related protein 2; AUC; area under the curve; BAL; bronchoalveolar lavage; circRNA; circular RNA; CSE; cigarette smoke extract; CTC; circulating tumor
Akt/PKB signaling regulates cigarette smoke-induced pulmonary epithelial-mesenchymal transition
Keywords: عصاره سیگار سیگار; COPD; chronic obstructive pulmonary disease; NSCLC; non small cell lung cancer; CS; Cigarette smoke; CSE; cigarette smoke extract; 1TGF-β; transforming growth factor β1; α-SMA; alpha-smooth muscle actin; EMT; epithelial-mesenchymal transition; ATNA; an
Crosstalk between mAChRM3 and β2AR, via acetylcholine PI3/PKC/PBEP1/Raf-1 MEK1/2/ERK1/2 pathway activation, in human bronchial epithelial cells after long-term cigarette smoke exposure
Keywords: عصاره سیگار سیگار; CSE; Cigarette Smoke Extract; ChAT; choline acetyltransferase; ACh; acetylcholine; mAChRs; Muscarinic Acetylcholine receptors; β2ARs; β2 Adrenergic receptors; PEBP1; phosphatidylethanolamine binding protein 1; ROS; Reactive oxigen species; NOX-4; NADPH
HDAC2 Suppresses IL17A-Mediated Airway Remodeling in Human and Experimental Modeling of COPD
Keywords: عصاره سیگار سیگار; airway inflammation; airway remodeling; COPD; HDAC2; IL-17A; CS; cigarette smoke; CSE; cigarette smoke extract; CXCL; chemokine (C-X-C motif) ligand; ECM; extracellular matrix; HBE; human bronchial epithelial; HDAC; histone deacetylase; HRCT; high-resolut
AMPK alleviates endoplasmic reticulum stress by inducing the ER-chaperone ORP150 via FOXO1 to protect human bronchial cells from apoptosis
Keywords: عصاره سیگار سیگار; AMP-activated kinase; Apoptosis; Cigarette smoke extract; COPD; ORP150; ER stress;
Cigarette Smoke Induces Stem Cell Features of Pancreatic Cancer Cells via PAF1
Keywords: عصاره سیگار سیگار; PHF5A; ERK; Pancreatic Carcinogenesis; Nicotine Receptor Signaling; AF; autofluorescence; ALDH; aldehyde dehydrogenase; AP-1; Activator Protein-1; C-CSE; commercial CSE; ChIP; chromatin immunoprecipitation; CHRNA7; cholinergic receptor nicotinic alpha 7
Role of GPx3 in PPARγ-induced protection against COPD-associated oxidative stress
Keywords: عصاره سیگار سیگار; COPD; chronic obstructive pulmonary disease; ROS; reactive oxygen species; GSH; glutathione; GPx; GSH peroxidase; PPARγ; Peroxisome proliferator-activated receptor γ; NF-κB; nuclear factor-κB; CSE; cigarette smoke extract; HBE; human bronchial epithel
Cigarette smoke condensate alters Saccharomyces cerevisiae efflux transporter mRNA and activity and increases caffeine toxicity
Keywords: عصاره سیگار سیگار; ABC transporter; Pdr5; Snq2; Cigarette smoke; Caffeine; Saccharomyces cerevisiae; ABC; ATP-binding cassette; AαC; 2-amino-9H-pyrido[23-b]indole; 4- ABP; 4-aminobiphenyl; BaP; benzo(a)pyrene; BLAST; Basic local alignment search tool; BCRP; breast cancer r
N-acetyl cysteine reverts the proinflammatory state induced by cigarette smoke extract in lung Calu-3 cells
Keywords: عصاره سیگار سیگار; ATP; adenosine triphosphate; cAMP; 3',5'-cyclic adenosine monophosphate; CF; cystic fibrosis; , cROS; cytoplasmic ROS; CFTR; cystic fibrosis transmembrane conductance regulator; mCx-I-III; mitochondrial NADH-cytochrome c oxidoreductase; COPD; Chronic obst
Identification of 5-hydroxymethylfurfural in cigarette smoke extract as a new substrate metabolically activated by human cytochrome P450 2A13
Keywords: عصاره سیگار سیگار; CYP; cytochrome P450; CYP2A13; cytochrome P450 2A13; CYP2A5; cytochrome P450 2A5; 8-MOP; 8-methoxypsoralen; BEAS-2B; immortalized human bronchial epithelial cells; B-2A13; BEAS-2B cells stably expressing CYP2A13; CSE; cigarette smoke extract; TSNA; tobacc
Calpeptin attenuates cigarette smoke-induced pulmonary inflammation via suppressing calpain/IκBα signaling in mice and BEAS-2B cells
Keywords: عصاره سیگار سیگار; CS; cigarette smoke; COPD; chronic obstructive pulmonary disease; CSE; cigarette smoke extract; PS; physiological saline; EPI or EPII; type I or II alveolar epithelial cells; NF-κB; nuclear factor-κB; DMSO; dimethylsulfoxide; NC; normal control; CS1-3;
Cigarette smoking represses expression of cytokine IL-12 and its regulator miR-21-An observational study in patients with coronary artery disease
Keywords: عصاره سیگار سیگار; ath-159a; Arabidopsis thaliana-159a; ASCET; Aspirin non-responsiveness and Clopidogrel Endpoint Trial; CSE; cigarette smoke extract; Ct; cycle threshold; EDTA; ethylenediaminetetraacetic acid; HWE; Hardy-Weinberg equilibrium; let-7; Caenorhabditis elegans
Protective effect of polyacetylene from Dendropanax morbifera Leveille leaves on pulmonary inflammation induced by cigarette smoke and lipopolysaccharide
Keywords: عصاره سیگار سیگار; Pulmonary inflammation; Cigarette smoke; Dendropanax morbifera leaves; Polyacetylene; (9Z, 16S)-16-Hydroxy-9,17-octadecadiene-12,14-diynoic acid (PubChem CID: 53890706); COPD; chronic obstructive pulmonary disease; CSE; cigarette smoke extract; CS; cigare
Cigarette smoke extract induces epithelial-mesenchymal transition of human bladder cancer T24 cells through activation of ERK1/2 pathway
Keywords: عصاره سیگار سیگار; CSE; Cigarette smoke extract; CS; Cigarette smoke; EMT; Epithelial-mesenchymal transition; MAPK; Mitogen-activated protein kinase; ERK1/2; extracellular regulated protein kinases 1 and 2; AP-1; activator protein 1; DMSO; dimethyl sulfoxide; MTT; thiazol
Role of Nrf2 and protective effects of Metformin against tobacco smoke-induced cerebrovascular toxicity
Keywords: عصاره سیگار سیگار; ARE; Anti-oxidant response element; BBB; Blood-brain barrier; COPD; Chronic obstructive pulmonary disease; CS; Cigarette smoke; CSE; Cigarette smoke extract; 2DM; Type 2 diabetes mellitus; FITC; Fluorescein isothiocyanate; FTC; Federal trade control; Glut
Cigarette smoke extracts induce overexpression of the proto-oncogenic gene interleukin-13 receptor α2 through activation of the PKA-CREB signaling pathway to trigger malignant transformation of lung vascular endothelial cells and angiogenesis
Keywords: عصاره سیگار سیگار; Lung cancer; Cigarette smoke extract; Angiogenesis; Tumor-associated endothelial cells; IL-13Rα2; CT-19;
Rac1 signaling regulates cigarette smoke-induced inflammation in the lung via the Erk1/2 MAPK and STAT3 pathways
Keywords: عصاره سیگار سیگار; COPD; chronic obstructive pulmonary disease; CS; cigarette smoke; CSE; cigarette smoke extract; IL-6; interleukin-6; IL-8; interleukin-8; KC; keratinocyte-derived chemokine; NSC; NSC23766, Rac1 inhibitor; Erk1/2; extracellular regulated protein kinases; M
Effect of cigarette smoke extract on P-glycoprotein function in primary cultured and newly developed alveolar epithelial cells
Keywords: عصاره سیگار سیگار; Cigarette smoke extract; Alveolar epithelial cells; Transdifferentiation; P-glycoprotein; Rhodamine 123;
Cigarette smoke extract alters the cell cycle via the phospholipid transfer protein/transforming growth factor-β1/CyclinD1/CDK4 pathway
Keywords: عصاره سیگار سیگار; Phospholipid transfer protein; Cell cycle; Cigarette smoke extract; Transforming growth factor-β1
Cigarette smoke extract induces apoptosis of rat alveolar Type II cells via the PLTP/TGF-β1/Smad2 pathway
Keywords: عصاره سیگار سیگار; Cigarette smoke extract; Phospholipid transfer protein; Transforming growth factor-β1; Smad2; Apoptosis; Alveolar Type II cells
M2 polarized macrophages induced by CSE promote proliferation, migration, and invasion of alveolar basal epithelial cells
Keywords: عصاره سیگار سیگار; Cigarette smoke extract; Alveolar basal epithelial cells; Proliferation; Migration; Invasion; M2 polarization; Macrophage
Supplementing Defect in Club Cell Secretory Protein Attenuates Airway Inflammation in COPD
Keywords: عصاره سیگار سیگار; ALI; air-liquid interface; CCSP; club cell secretory protein; CSE; cigarette smoke extract; DAPI; 4â²,6-diamidino-2-phenylindole; EBB; endobronchial biopsy specimen; LDH; lactate dehydrogenase; PBS; phosphate-buffered saline; rhCCSP; recombinant human cl
Sirtuins in vascular diseases: Emerging roles and therapeutic potential
Keywords: عصاره سیگار سیگار; ACE; angiotensin converting enzyme; AICAR; 5-amino-4-imidazolecarboxamide riboside; AMPK; AMP-activated protein kinase; Ang II; angiotensin II; ApoE; apolipoprotein E; AT1R; angiotensin II type 1 receptor; ATM; ataxia telangiectasia mutated; ATP; adenosin
The p-ERK–p-c-Jun–cyclinD1 pathway is involved in proliferation of smooth muscle cells after exposure to cigarette smoke extract
Keywords: عصاره سیگار سیگار; Cigarette smoke extract; Smooth muscle cell proliferation; ERK; c-Jun; CyclinD1
Aldehyde dehydrogenase 3A1 protects airway epithelial cells from cigarette smoke-induced DNA damage and cytotoxicity
Keywords: عصاره سیگار سیگار; AHR; aryl hydrocarbon receptor; ALDH; aldehyde dehydrogenase; CDK; cyclin-dependent kinase; COPD; chronic obstructive pulmonary disease; CS; cigarette smoke; CSE; cigarette smoke extract; DDR; DNA damage response; FA; Fanconi anemia; FANCD2; a member of t
Pathological changes in the COPD lung mesenchyme - Novel lessons learned from in vitro and in vivo studies
Keywords: عصاره سیگار سیگار; Chronic obstructive pulmonary disease; Inflammation; Extra cellular matrix; Epithelial-mesenchymal interactions; Novel pharmacological targets; CSE; cigarette smoke extract; COPD; chronic obstructive pulmonary disease; EMT; epithelial-mesenchymal tran
SIRT4 inhibits cigarette smoke extracts-induced mononuclear cell adhesion to human pulmonary microvascular endothelial cells via regulating NF-κB activity
Keywords: عصاره سیگار سیگار; COPD; chronic obstructive pulmonary disease; CS; cigarette smoking; CSE; cigarette smoking extracts; VCAM-1; vascular cell adhesion molecule-1; HPMECs; human pulmonary microvascular endothelial cells; FBS; fetal bovine serum; Ad-SIRT4; adenoviral SIRT4; H
Cigarette smoke exposure is associated with vitamin D3 deficiencies in patients with chronic rhinosinusitis
Keywords: عصاره سیگار سیگار; Vitamin D; secondhand smoke; sinusitis; epithelial cell; BEGM; Basal epithelial cell growth medium; CRS; Chronic rhinosinusitis; CRSsNP; Chronic rhinosinusitis without nasal polyps; CRSwNP; Chronic rhinosinusitis with nasal polyps; CS; Cigarette smoke; CS
The NF-κB family member RelB regulates microRNA miR-146a to suppress cigarette smoke-induced COX-2 protein expression in lung fibroblasts
Keywords: عصاره سیگار سیگار; CD40L; CD40 ligand; COPD; chronic obstructive pulmonary disease; COX-2; cyclooxygenase-2; CSE; cigarette smoke extract; miRNA; microRNA; NF-κB; nuclear factor-κB; RLU; relative luciferase units; TNF-α; tumor necrosis factor-α; MicroRNA; Cyclooxygenase
Cigarette smoke-induced alveolar epithelial-mesenchymal transition is mediated by Rac1 activation
Keywords: عصاره سیگار سیگار; EMT; epithelial-mesenchymal transition; COPD; chronic obstructive pulmonary disease; CSE; cigarette smoke extract; TGF-β1; transforming growth factor β1; α-SMA; α-smooth muscle actin; MMP-9; matrix metalloproteinases-9; ATNA; anti-TGF-β1 neutralizi
Oxidative stress induces mitochondrial dysfunction and a protective unfolded protein response in RPE cells
Keywords: عصاره سیگار سیگار; AMD; age-related macular degeneration; ATF4; activating transcription factor 4; ATF6; activating transcription factor 6; CHOP; CCAAT/enhancer-binding protein-homologous protein; C/EBP-β; CCAAT/enhancer binding protein β; CSE; cigarette smoke extract; IR
Vitamin C forestalls cigarette smoke induced NF-κB activation in alveolar epithelial cells
Keywords: عصاره سیگار سیگار; CSE; cigarette smoke extract; CS; cigarette smoke; NF-κB; nuclear factor kappa-B; ROS; reactive oxygen species; EMSA; electrophoretic mobility shift assay; FACS; fluorescence activated cell sorter; DCFH-DA; 2â²,7â²-dichlorofluorescin diacetate; DCF; 2â
Toxicological effects of cigarette smoke on Ana-1 macrophages in vitro
Keywords: عصاره سیگار سیگار; Ana-1 cell; Cigarette smoke extract; Apoptosis; Mitochondrial membrane potential; Oxidative stress; NF-κB;
Comparative antioxidant effects of lycopene, apo-10â²-lycopenoic acid and apo-14â²-lycopenoic acid in human macrophages exposed to H2O2 and cigarette smoke extract
Keywords: عصاره سیگار سیگار; BHT; butylated hydroxytoluene; CMO2; carotenoid 9â²10â²-monooxygenase 2; Cox-2; cyclooxygenase-2; CSE; cigarette smoke extract; DCF; dichlorodihydrofluorescein diacetate; ERK1/2; extracellular signal-regulated kinase 1/2; HO-1; heme oxygenase-1; 8-OHdG;
A review of in vitro cigarette smoke exposure systems
Keywords: عصاره سیگار سیگار; ALI; air-liquid interface; BAT; British American Tobacco; COPD; chronic obstructive pulmonary disease; CORESTA; Cooperation Centre for Scientific Research Relative to Tobacco; CSE; cigarette smoke extract; CuO; copper oxide nanoparticles; DMSO; dimethyl