Keywords: سمیت سلولی وابسته به مکمل; Lectins; Molecular farming; Monoclonal antibodies; Plant secondary metabolites; Therapeutic anti-cancer vaccines; APIs; active pharmaceutical ingredients; ADCC; antibody-dependent cellular cytotoxicity; ADCs; antibody-drug conjugates; ATPS; aqueous two-
مقالات ISI سمیت سلولی وابسته به مکمل (ترجمه نشده)
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Keywords: سمیت سلولی وابسته به مکمل; Monocytic myeloid-derived suppressor cells; Renal transplant; Post-infectious immunosuppression; CARS; compensatory anti-inflammatory response syndrome; MDSCs; myeloid-derived suppressor cells; M-MDSCs; monocytic myeloid-derived suppressor cells; PMN-MDSC
Keywords: سمیت سلولی وابسته به مکمل; DSA; Heart transplantation; Donor-specific; Antibody-mediated; Anti-HLA; cAMR; chronic AMR; CDC; complement-dependent cytotoxicity; FCXM; flow-cytometry cross-match; HTx; heart transplantation; MMF; mycophenolate mofetil; pAMR; pathology diagnostic criter
Keywords: سمیت سلولی وابسته به مکمل; ADA; antidrug antibody; ALI/ARDS; acute lung injury/acute respiratory distress syndromes; Ab; antibody; ADC; antibody drug conjugate; ADCC; antigen-dependent cellular cytotoxicity; BAL; bronchoalveolar lavage; BsAbs; bispecific antibodies; CCL; CC chemoki
Keywords: سمیت سلولی وابسته به مکمل; AMR; antibody-mediated rejection; BOS; Bronchiolitis obliterans syndrome; CDC; complement-dependent cytotoxicity; CLAD; chronic lung allograft dysfunction; DSA; donor-specific antibody; HLA; human leukocyte antigen; ISHLT; International Society for Heart
Keywords: سمیت سلولی وابسته به مکمل; ADCC; antibody dependent cellular cytotoxicity; ADCP; antibody-dependent cellular phagocytosis; BCG; bacillus calmette-guérin; CDC; complement-dependent cytotoxicity; CSF-1; colony stimulating factor 1; CTL; cytotoxic T lymphocyte; EGFR; epithelial growt
Keywords: سمیت سلولی وابسته به مکمل; CDC; complement-dependent cytotoxicity; MAC; membrane attack complex; mCRP; membrane-bound complement regulatory protein; siRNA; small interfering RNA; ADCC; antibody-dependent cellular cytotoxicity; CDCC; complement-dependent cellular cytotoxicity; RTX;
Keywords: سمیت سلولی وابسته به مکمل; ABMR; Antibody mediated rejection; aHUS; Atypical hemolytic syndrome; AP; Alternative pathway; DBD; Deceased brain dead; DCD; Deceased cardiac death; DSA; Donor specific antibodies; C1-INH; C1-inhibitor; C3; Complement component C3; CDC; Complement-depend
Comparability study of Rituximab originator and follow-on biopharmaceutical
Keywords: سمیت سلولی وابسته به مکمل; AA; amino acid; ABC; ammonium bicarbonate; ACN; acetonitrile; ADCC; antibody-dependent cellular cytotoxicity; CD; circular dichroism; CDC; complement-dependent cytotoxicity; CDRs; complementarity determining regions; CH; constant region of heavy chain; CH
Keywords: سمیت سلولی وابسته به مکمل; ADA; anti-drug antibody; ADCC; antibody-dependent cell cytotoxicity; ADCP; antibody-dependent cell phagocytosis; BiTE; bi-specific T cell engagers; CDC; complement-dependent cytotoxicity; CRA; cytokine release assays; CRS; cytokine release syndrome; DC; d
Keywords: سمیت سلولی وابسته به مکمل; mAb; charge heterogeneity; C-terminal Lys deletion; Lys and Gly deletion; pharmacokinetics; bioavailability; ATA; anti-therapeutic antibody; CDC; complement-dependent cytotoxicity; CL; clearance; ELISA; enzyme-linked immunosorbent assay; Fab; fragment ant
Keywords: سمیت سلولی وابسته به مکمل; ADCC; antibody-dependent cell-mediated cytotoxicity; CDC; complement-dependent cytotoxicity; ADCP; antibody-dependent phagocytosis; ELISA; enzyme-linked immunoabsorbant assay; gluV8; glutamyl endopeptidase I; IdeS; immunoglobulin G-degrading enzyme of str
Keywords: سمیت سلولی وابسته به مکمل; ADCC; antibody-dependent cellular cytotoxicity; CDC; complement-dependent cytotoxicity; cDNA; complementary DNA; CEL-seq; single-cell RNA-sequencing; DOC; doxorubicin; EMA; European Medicines Agency; ER; estrogen receptor; FRα; folate receptor alpha; HER
Keywords: سمیت سلولی وابسته به مکمل; 2D-LC; two-dimensional liquid chromatography; AA; amino acid; AC; affinity chromatography; ADC; antibody-drug conjugates; ADCC; antibody-dependent cellular cytotoxicity; AF4; asymmetric flow field fractionation; APTS; 1-aminopyrene-3,6,8-trisulfonate; Asn
Keywords: سمیت سلولی وابسته به مکمل; RA; rheumatoid arthritis; IFX; infliximab; ETN; etanercept; ADCC; antibody-dependent cellular cytotoxicity; CDC; complement-dependent cytotoxicity; CCP; cyclic citrullinated peptide; RF; rheumatoid factor; MMP-3; matrix-metalloproteinase-3; DAS28-ESR; dis
Keywords: سمیت سلولی وابسته به مکمل; Antibodies; Immunoconjugates; Immunotoxins; Ab; antibody; Ag; antigen; ADCC; antibody-dependent cell mediated cytotoxicity; ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; AKT; protein kinase B; APC; antigen-presenting cell; Apo2L/TRAIL; t
Keywords: سمیت سلولی وابسته به مکمل; Immunocytokines; Antibody-cytokine fusion proteins; Targeted cancer immunotherapy; ADCC; antibody-dependent cellular cytotoxicity; AICD; activation-induced cell death; APC; antigen presenting cell; CDC; complement-dependent cytotoxicity; CEA; carcinoemb
Keywords: سمیت سلولی وابسته به مکمل; ADCC; antibody-dependent cellular cytotoxicity; AQP4; aquaporin-4; BSA; bovine serum albumin; CDC; complement-dependent cytotoxicity; CNS; central nervous system; dSTORM; direct stochastic reconstruction microscopy; EDSS; expanded disability status scale;
Graft immunologic events in deceased donor kidney transplant recipients with preformed HLA-donor specific antibodies
Keywords: سمیت سلولی وابسته به مکمل; Kidney transplant; Deceased donor; Acute rejection; Donor-specific antibodies; HLA-antibodies; %PRA; panel reactive antibody percentage; AMR; antibody mediated rejection; ACR; acute cellular rejection; AR; acute rejection; CDC; complement-dependent cytoto
Donor-specific HLA antibodies in predicting crossmatch outcome: Comparison of three different laboratory techniques
Keywords: سمیت سلولی وابسته به مکمل; Crossmatch; Donor-specific antibodies; HLA antibodies; Kidney transplantation; Solid-phase assay; AUC; area under curve; CDC; Complement-dependent cytotoxicity; CDCXM; Complement-dependent cytotoxicity crossmatch; DSA; donor specific antibodies; DTT; dith
Effects of amino acid substitutions on the biological activity of anti-CD20 monoclonal antibody produced by transgenic silkworms (Bombyx mori)
Keywords: سمیت سلولی وابسته به مکمل; Monoclonal antibody; Transgenic silkworm; Amino acid substitution; N-glycosylation; Fc-mediated effector function; ADCC; antibody-dependent cellular cytotoxicity; ADCP; antibody-dependent cellular phagocytosis; CBB; Coomassie Brilliant Blue; CDC; compleme
Improving the performance of virtual crossmatch results by correlating with nationally-performed physical crossmatches: Obtaining additional value from proficiency testing activities
Keywords: سمیت سلولی وابسته به مکمل; DSA; Donor Specific Antibody/Donor Specific Allo-antibody; CAP; College of American Pathologists; AMR; antibody-mediated rejection; XM; Cross Match; FC; Flow Cytometry; SABA; Single Antigen Bead Assay; UA; Unacceptable Antigen; SD; Standard Deviation; MFI
Transitioning from first- to second-generation biosimilars: An appraisal of regulatory and post-marketing challenges
Keywords: سمیت سلولی وابسته به مکمل; ACR; American College of Rheumatology; ADAb; anti-drug antibody; ADCC; antibody-dependent cell-mediated cytotoxicity; AIFA; Italian Medicines Agency; CDC; complement-dependent cytotoxicity; CHMP; Committee for Medicinal Products for Human Use; DAS28; 28-j
Rapid optimized flow cytometric crossmatch (FCXM) assays: The Halifax and Halifaster protocols
Keywords: سمیت سلولی وابسته به مکمل; 3SD; 3 standard deviations; CDC; complement-dependent cytotoxicity; DSA; donor-specific HLA antibodies; FCXM; flow cytometry crossmatch; FWB; flow wash buffer; HLA; human leukocyte antigen; MCF; median channel fluorescence; MCFS; median channel fluorescen
Glycosimilarity assessment of biotherapeutics 1: Quantitative comparison of the N-glycosylation of the innovator and a biosimilar version of etanercept
Keywords: سمیت سلولی وابسته به مکمل; APTS; 8-aminopyrene-1,3,6-trisulfonic acid; CGE-LIF; capillary gel electrophoresis - laser induced fluorescence; CQA; critical quality attributes; ADCC; antibody-dependent cell-mediated cytotoxicity; CDC; complement-dependent cytotoxicity; Fc; fragment
Recombinant IgG1 Fc hexamers block cytotoxicity and pathological changes in experimental in vitro and rat models of neuromyelitis optica
Keywords: سمیت سلولی وابسته به مکمل; AQP4; NMO; Fc multimer; Astrocyte; Complement; Immunoglobulin; Neuroinflammation; ADCC; antibody-dependent cellular cytotoxicity; AQP4; aquaporin-4; AQP4-IgG; neuromyelitis optica immunoglobulin G antibody; BSA; bovine serum albumin; CDC; complement-depen
Improved process robustness, product quality and biological efficacy of an anti-CD52 monoclonal antibody upon pH shift in Chinese hamster ovary cell perfusion culture
Keywords: سمیت سلولی وابسته به مکمل; pH; Glycosylation; Charge heterogeneity; Complement-dependent cytotoxicity; Antibody-dependent cell-mediated cytotoxicity; Perfusion;
Hexamerization-enhanced CD20 antibody mediates complement-dependent cytotoxicity in serum genetically deficient in C9
Keywords: سمیت سلولی وابسته به مکمل; CDC; complement-dependent cytotoxicity; CLL; chronic lymphocytic leukemia; C9-D; serum genetically deficient in C9; MAC; membrane attack complex containing C5b,C6,C7,C8 and multiple copies of C9; NHS; normal human serum; RTX; rituximab; Complement; Immuno
New insights in the pathogenesis of immunoglobulin A vasculitis (Henoch-Schönlein purpura)
Keywords: سمیت سلولی وابسته به مکمل; ADCC; antibody-dependent cellular cytotoxicity; AECA; Anti-epithelial cell antibodies; ANCA; Anti-neutrophil cytoplasmic antibodies; β2GPI; β2-glycoprotein I; CDC; Complement-dependent cytotoxicity; EC; endothelial cell; FcαRI; Fc receptor for IgA; Gal
Negative regulation of HLA-DR expression on endothelial cells by anti-blood group A/B antibody ligation and mTOR inhibition
Keywords: سمیت سلولی وابسته به مکمل; ABO-I; ABO-incompatible kidney transplantation; CAMR; chronic antibody mediated rejection; CDC; complement-dependent cytotoxicity; CIITA; class II transactivator; DSA; donor-specific antibody; HLA-I; HLA-incompatible kidney transplantation; Kidney transpl
The Antitumor Activity of IMGN529, a CD37-Targeting Antibody-Drug Conjugate, Is Potentiated by Rituximab in Non-Hodgkin Lymphoma Models
Keywords: سمیت سلولی وابسته به مکمل; ADC; antibody-drug conjugate; NHL; non-Hodgkin lymphoma; DLBCL; diffuse large B-cell lymphoma; ADCC; antibody-dependent cell-mediated cytotoxicity; CDC; complement-dependent cytotoxicity; MMAE; monomethyl auristatin E; SMCC; N-succinimidyl-4-(N-maleimidoe
Humanization of JAA-F11, a Highly Specific Anti-Thomsen-Friedenreich Pancarcinoma Antibody and InVitro Efficacy Analysis
Keywords: سمیت سلولی وابسته به مکمل; Ab; Antibodies; ADCC; Antibody-dependent cellular cytotoxicity; Ag; Antigen; BLAST; Basic local alignment search tool; BSA; Bovine serum albumin; CDC; Complement-dependent cytotoxicity; CDRs; Complementarity determining regions; CHO; Chinese hamster ovary
Low expression of complement inhibitory protein CD59 contributes to humoral autoimmunity against astrocytes
Keywords: سمیت سلولی وابسته به مکمل; CD59; AQP4; Neuromyelitis optica spectrum disorders; Complement-dependent cytotoxicity;
Using an in vitro xenoantibody-mediated complement-dependent cytotoxicity model to evaluate the complement inhibitory activity of the peptidic C3 inhibitor Cp40
Keywords: سمیت سلولی وابسته به مکمل; α-Gal; Galα1-3Gal; CDC; complement-dependent cytotoxicity; FACS; fluorescence-activated cell sorter; Gmean; geometric mean fluorescence intensity; HINHS; heat-inactivated normal human serum; HINMS; heat-inactivated normal monkey serum; iPEC; SV40-immort
Selection and characterization of single domain antibodies against human CD20
Keywords: سمیت سلولی وابسته به مکمل; RTX; rituximab; SdAb; single domain antibody; CDR; complementarity determining region; FR; framework region; Bt; biotinylated; NA-PE; NeutrAvidin-phycoerythrin conjugate; Ab; antibody; CDC; complement-dependent cytotoxicity; CD20; Single domain antibody
Real-time analysis of the detailed sequence of cellular events in mAb-mediated complement-dependent cytotoxicity of B-cell lines and of chronic lymphocytic leukemia B-cells
Keywords: سمیت سلولی وابسته به مکمل; Al; Alexa Fluor; CLL; chronic lymphocytic leukemia; CDC; complement-dependent cytotoxicity; GMI; geometrical mean intensity; HI; heat inactivated; Hx; hexamerization enchanced; MAC; membrane attack complex; MESF; molecules of equivalent soluble fluorochro
Near infrared photoimmunotherapy of B-cell lymphoma
Keywords: سمیت سلولی وابسته به مکمل; Near infrared photoimmunotherapy; CD20; B-cell lymphoma; Monoclonal antibodies; Near infrared light; Molecular imaging; ADCC; antibody-dependent cell-mediated cytotoxicity; APC; antibody-photo absorber conjugate; CD; cluster of differentiation; CDC; compl
Antibodies against HLA-DP recognize broadly expressed epitopes
Keywords: سمیت سلولی وابسته به مکمل; CDC; complement-dependent cytotoxicity; DSA; donor specific antibodies; HVR; hypervariable region; MFI; mean fluorescence intensity; SRPs; selective reactivity patterns; SABs; single antigen beads; HLA; HLA-DP antibodies; Epitopes; Transplant;
Complement triggers relocation of Mortalin/GRP75 from mitochondria to the plasma membrane
Keywords: سمیت سلولی وابسته به مکمل; AF488; Alexa Fluor 488; AU; arbitrary units; MAC; complement membrane attack complex; CDC; complement-dependent cytotoxicity; C5b-9; complement terminal complex composed of C5b, C6, C7, C8, and C9; C9-AF546; human complement C9 tagged with Alexa Fluor 546
Structural consequences of aglycosylated IgG Fc variants evolved for FcγRI binding
Keywords: سمیت سلولی وابسته به مکمل; Fc; fragment crystallizable; IgG; immunoglobulin G; Fab; fragment antigen binding; FcγR; Fc gamma receptor; ADCC; antibody-dependent cell-mediated cytotoxicity; ADCP; antibody-dependent cell-mediated phagocytosis; CDC; complement-dependent cytotoxicity;
Haematopoietic depletion in vaccine-induced neonatal pancytopenia depends on both the titre and specificity of alloantibody and levels of MHC I expression
Keywords: سمیت سلولی وابسته به مکمل; Bovine neonatal pancytopenia (BNP); Alloantibody; Major Histocompatibility Complex class I (MHC I); Complement-dependent cytotoxicity; Veterinary vaccines; BNP; Bovine neonatal pancytopenia; BVDV; Bovine Viral Diarrhoea Virus; CDC assay; complement-depend
Next-generation optimized biotherapeutics - A review and preclinical study
Keywords: سمیت سلولی وابسته به مکمل; ADAs; anti-drug antibodies; ADC; antibody drug conjugate; ADCC; antibody-dependent cell-mediated cytotoxicity; ATL; adult T-cell leukemia-lymphoma; CCR4; CC chemokine receptor 4; CDC; complement-dependent cytotoxicity; CDR; complementary determining regio
Research ArticleA phase II study of cixutumumab (IMC-A12, NSC742460) in advanced hepatocellular carcinoma
Keywords: سمیت سلولی وابسته به مکمل; IgG1; Immunoglobulin 1; IGF-1R; Insulin growth factor 1 receptor; IGF-1; Insulin growth factor 1; MAP; Mitogen activated protein; ADCC; Antibody-dependent complement-mediated cytotoxicity; CDC; Complement-dependent cytotoxicity; IGF-2; Insulin growth fact
Validated detection of human anti-chimeric immune responses in serum of neuroblastoma patients treated with ch14.18/CHO
Keywords: سمیت سلولی وابسته به مکمل; mAb; monoclonal antibody; NB; neuroblastoma; anti-Id; anti-idiotype; HACA; human anti-chimeric antibody; ELISA; enzyme-linked immunosorbent assay; CV; coefficient of variation; LOD; limit of detection; QC; quality controls; CDC; complement-dependent cytot
Evaluation of a fully human monoclonal antibody against multiple influenza A viral strains in mice and a pandemic H1N1 strain in nonhuman primates
Keywords: سمیت سلولی وابسته به مکمل; M2; matrix protein 2; M2e; ectodomain of M2; mAb; monoclonal antibody; ADCC; antibody-dependent cell-mediated cytotoxicity; CDC; complement-dependent cytotoxicity; HA; hemagglutinin; NA; neuraminidase; Influenza A; Matrix protein 2; Antibody; Virus infect
Longitudinally extensive NMO spinal cord pathology produced by passive transfer of NMO-IgG in mice lacking complement inhibitor CD59
Keywords: سمیت سلولی وابسته به مکمل; NMO; Aquaporin-4; Astrocyte; Complement-dependent cytotoxicity; Demyelination
Development of a robust reporter-based ADCC assay with frozen, thaw-and-use cells to measure Fc effector function of therapeutic antibodies
Keywords: سمیت سلولی وابسته به مکمل; ADCC; antibody-dependent cell-mediated cytotoxicity; CDC; complement-dependent cytotoxicity; PBMC; peripheral blood mononuclear cell; NK cells; natural killer cells; LDH; lactate dehydrogenase; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; EC50; measur
Predicted indirectly recognizable HLA epitopes presented by HLA-DR correlate with the de novo development of donor-specific HLA IgG antibodies after kidney transplantation
Keywords: سمیت سلولی وابسته به مکمل; CDC; complement-dependent cytotoxicity; DSA; donor-specific antibodies; HLA; human leukocyte antigens; PRA; panel-reactive HLA antibody; PIRCHE; predicted indirectly recognizable HLA epitope; PIRCHE-II; PIRCHE presented by HLA class II;
Hepatitis B virus X protein protects hepatoma and hepatic cells from complement-dependent cytotoxicity by up-regulation of CD46
Keywords: سمیت سلولی وابسته به مکمل; HBx; hepatitis B virus X protein; HCC; hepatocellular carcinoma; mCRPs; membrane-bound complement regulatory proteins; CDC; complement-dependent cytotoxicity; COX-2; cyclooxygenase-2; PGE2; prostaglandin E2; CREB; cAMP response element-binding protein; RN
Optic neuritis in neuromyelitis optica
Keywords: سمیت سلولی وابسته به مکمل; NMO; Optic nerve; Aquaporin-4; Devic's disease; Neuroinflammation; ADCC; antibody-dependent cell-mediated cytotoxicity; AQP4; aquaporin-4; BBB; blood-brain barrier; CDC; complement-dependent cytotoxicity; CDCC; complement-dependent cell-mediated cytotox