Keywords: گیرنده آندروستان پایدار; Polychlorinated biphenyls; Signalling disruption; Secondary necrosis; Casein kinase 2; AKT; Serine/Threonine kinase 1; CAR; Constitutive androstane receptor; CASP3; Caspase-3; CD; Control diet; CD+; Control diet + Aroclor 1260 exposure; CDK; Cyclin depend
مقالات ISI گیرنده آندروستان پایدار (ترجمه نشده)
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Keywords: گیرنده آندروستان پایدار; BMI; Body mass index; CVD; Cardiovascular disease; CAR; Constitutive androstane receptor; GFR; Glomerular filtration rate; HCB; Hexachlorobenzene; HDL; High density lipoprotein; IVS; Inter ventricular septum; LDL; Low density lipoprotein; LVEDD; Left vent
Keywords: گیرنده آندروستان پایدار; Rodent liver tumors; Nongenotoxic; Mode of action; Constitutive Androstane Receptor; Peroxisome proliferator-activated receptor alpha (PPARα);
Keywords: گیرنده آندروستان پایدار; 9c; 9-cis retinoic acid; AF1 (or 2); activation function 1(or 2); AR; androgen receptor; CAR; constitutive androstane receptor; ChIP; chromatin immunoprecipitation; DBD; DNA binding domain; ER; estrogen receptor; ERE; estrogen response elements; GR; gluco
Keywords: گیرنده آندروستان پایدار; 11βHSD; 11β-Hydroxysteroid dehydrogenase; ABC; ATP-binding cassette; AhR; aryl hydrocarbon receptor; ARNT; aryl hydrocarbon receptor nuclear translocator; BCRP; breast cancer resistance protein; CAR; constitutive androstane receptor; CYP; cytochrome P45
Keywords: گیرنده آندروستان پایدار; AHR; aryl hydrocarbon receptor; ALD; alcoholic liver disease; BAs; bile acids; CAR; constitutive androstane receptor; CARM1; coactivator associated arginine methyltransferases 1; CBP/P300; CREB-binding protein/p300; CYP27A1/Cyp27a1; sterol 27α-hydroxylas
Keywords: گیرنده آندروستان پایدار; ADME; absorption, distribution, metabolism and excretion; AFND; allele frequency net database; ALT; alanine aminotransferase; AOP; adverse outcome pathway; AOP-KB; AOP knowledge base; AST; aspartate aminotransferase; BSEP; bile salt export protein; CAR; c
Keywords: گیرنده آندروستان پایدار; AhR; aryl hydrocarbon receptor; BMI; body mass index; BDE-47; tetra-bromodiphenyl ether; CAR; constitutive androstane receptor; DDE; dichlorodiphenyl dichloroethene; DDT; dichlorodiphenyl trichloroethane; EDCs; endocrine disrupting chemicals; GDM; gestati
Keywords: گیرنده آندروستان پایدار; Triclosan; Constitutive androstane receptor; Peroxisome proliferator-activated receptor alpha; Rodent liver; Non-genotoxic carcinogens; Mechanism of action; ACO; peroxisomal Acyl-CoA oxidase; AhR; aryl hydrocarbon receptor; ALT; alanine aminotransferase;
Keywords: گیرنده آندروستان پایدار; AhR; aryl hydrocarbon receptor; ANF; natriuretic peptide type A; AUC; area under the curve; BP; blood pressure; CAE; chloroacetate esterase; CAR; constitutive androstane receptor; CD; control diet; Cd36; cluster of differentiation 36; Cpt1a; carnitine pal
Keywords: گیرنده آندروستان پایدار; ABC; ATP-binding cassette transporter; ACACA; acetyl-CoA carboxylase α; ACACB; acetyl-CoA carboxylase β, ACLY, ATP citrate lyase; ACADM; medium-chain acyl-CoA dehydrogenase; ACOX1; acyl-CoA oxidase 1; AFB1; aflatoxin B1; AMPK; adenosine monophosphate-ac
Keywords: گیرنده آندروستان پایدار; ADMET; absorption, distribution, metabolism, excretion, toxicity; AHR; aryl hydrocarbon receptor; AUC; area under the curve; BVU; (E)-5-(2-bromovinyl) uracil; CAR; constitutive androstane receptor; cMOAT; Canalicular multispecific organic anion transporte
Keywords: گیرنده آندروستان پایدار; Constitutive androstane receptor; Glycolic genes; cMyc; Mitogen; TCPOBOP; Liver;
Keywords: گیرنده آندروستان پایدار; CAR; constitutive androstane receptor; CITCO; (6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehydeO-(3,4-dichlorobenzyl)oxime); eHx; extended hepatectomy; huCAR; humanized CAR; SFSS; small-for-size syndrome; sHx; standard hepatectomy; TCP; 1,4-bi
Keywords: گیرنده آندروستان پایدار; Ginkgo biloba extract (GBE); Liver hypertrophy; Hepatocarcinogenesis; Constitutive androstane receptor (CAR); GBE; Ginkgo biloba extract; CAR; Constitutive Androstane Receptor; WT; wild-type; CARKO; CAR knockout;
Keywords: گیرنده آندروستان پایدار; MoA; mode of action; HPT; hypothalamic pituitary thyroid; UGT; uridine diphosphate glucuronosyltransferase; NOAEL; no observed adverse effect level; CAR; Constitutive Androstane Receptor; PCBs; polychlorinated biphenyls; USEPA; United States Environmental
Keywords: گیرنده آندروستان پایدار; AR (NR3C4); androgen receptor; CAR (NR1I3); constitutive androstane receptor; COUP-TF (NR2F); chicken ovalbumin upstream promoter transcription factor; DAF-12; (abnormal) dauer formation (NR)-12; DAX-1 (NR0B1); dosage-sensitive sex reversal, adrenal hypop
Keywords: گیرنده آندروستان پایدار; AR; androgen receptor; CAR; constitutive androstane receptor; DBD; DNA-binding domain; EDC; endocrine disrupting chemical; ER; estrogen receptor; FXR; farnesoid X receptor; GR; glucocorticoid receptor; HRE; hormone responsive elements; LBD; ligand-binding
Keywords: گیرنده آندروستان پایدار; CYP; cytochrome P-450; GSH-transferase; glutathione-S-transferase; UDP-glucuronosyltransferase; uridine 5â²-diphospho-glucuronosyltransferase; EGb761®; Ginkgo biloba extract, CAS 122933-57-7; AhR; aryl hydrocarbon receptor; PXR; pregnane X receptor; CAR
Keywords: گیرنده آندروستان پایدار; Anticonvulsants; Aryl hydrocarbon receptor; Constitutive androstane receptor; Estrogen receptors; Glucocorticoid receptor; Pregnane X receptorAnticonvulsivos; Receptor de aril hidrocarburos; Receptor constitutivo de androstano; Receptores de los estrógeno
Keywords: گیرنده آندروستان پایدار; 5caC; 5-carboxylcytosine; 5fC; 5-formylcytosine; 5hmC; 5-hydroxymethylcytosine; 5mC; 5-methylcytosine; CAR; constitutive androstane receptor; CGI; CpG island; CpG; cytosinephosophate-guanine; CNV; copy number variation; DEN; diethylnitrosamine; DNMT; DNA
Keywords: گیرنده آندروستان پایدار; LPS; lipopolysaccharide; IL-6; interleukin-6; DMEs; drug-metabolizing enzymes; Ces (mouse) or CES (human); carboxylesterases; CYP; cytochrome P450; PXR; pregnane X receptor; CAR; constitutive androstane receptor; RXR; retinoid X receptor; NFκB; nuclear f
Keywords: گیرنده آندروستان پایدار; DMC; dimethylcrocetin; CHD; coronary heart disease; LDL; low density lipoprotein; ROS; reactive oxygen species; PCa; prostate cancer; COX-2; cycloxygenase-2; NF-κB; nuclear factor-κB; RAR; retinoid-like receptors; PPARγ; Peroxisome proliferator-activat
Keywords: گیرنده آندروستان پایدار; Ovarian cancer; Constitutive androstane receptor; Anticancer agents; Multiple drug resistance 1; Uridine diphosphate-5â²-glucuronosyltransferase 1A1;
Keywords: گیرنده آندروستان پایدار; CAR; constitutive androstane receptor; CYP2B6; cytochrome P450 2B6; CYP3A4; cytochrome P450 3A4; DMSO; dimethyl sulfoxide; GR; glucocorticoid receptor; HBSS; Hanks' balanced salt solution; hCAR; human constitutive androstane receptor; hGR; human glucoco
CAR-mediated repression of Cdkn1a(p21) is accompanied by the Akt activation
Keywords: گیرنده آندروستان پایدار; Constitutive androstane receptor; TCPOBOP; Liver; Akt; PTEN; Cdkn1a(p21);
A CYP2B6-humanized mouse model and its potential applications
Keywords: گیرنده آندروستان پایدار; CYP2B6; Liver; Drug metabolism; Xenobiotic toxicity; Knockout mice; Humanized mice; WT; wild-type; CYPs; cytochromes P450; CAR; constitutive androstane receptor; PXR; pregnane X receptor; GR; glucocorticoid receptor; PB; phenobarbital; and DEX; dexamethas
The CAR agonist TCPOBOP inhibits lipogenesis and promotes fibrosis in the mammary gland of adolescent female mice
Keywords: گیرنده آندروستان پایدار; ACC; acetyl-CoA carboxylase; α-SMA; alpha-smooth muscle actin; CAR; constitutive androstane receptor; FAS; fatty acid synthase; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; G6pase; glucose-6-phosphatase; Gon-WAT; gonadal white adipose tissue; H&E; he
Shikonin upregulates the expression of drug-metabolizing enzymes and drug transporters in primary rat hepatocytes
Keywords: گیرنده آندروستان پایدار; AhR; aryl hydrocarbon receptor; AP1; activating protein 1; ARE; antioxidant-response element; CAR; constitutive androstane receptor; CYP; cytochrome P450; DREs; dioxin-responsive elements; EMSA; electromobility gel shift assay; FBS; fetal bovine serum; GS
Comparison of the hepatic and thyroid gland effects of sodium phenobarbital in wild type and constitutive androstane receptor (CAR) knockout rats and pregnenolone-16α-carbonitrile in wild type and pregnane X receptor (PXR) knockout rats
Keywords: گیرنده آندروستان پایدار; Sodium phenobarbital; Pregnenolone-16α-carbonitrile; Constitutive androstane receptor; Pregnane X receptor; Receptor knockout rats; Cytochrome P450;
Significance of A-to-I RNA editing of transcripts modulating pharmacokinetics and pharmacodynamics
Keywords: گیرنده آندروستان پایدار; ABC; ATP-binding cassette transporter; ADAR; adenosine deaminase acting on RNA; ADH; alcohol dehydrogenase; AhR; aryl hydrocarbon receptor; AKR; aldo-keto reductase; ALS; amyotrophic lateral sclerosis; AZIN1; antizyme inhibitor 1; AMPA; α-amino-3-hydroxy
Essential oils of culinary herbs and spices activate PXR and induce CYP3A4 in human intestinal and hepatic in vitro models
Keywords: گیرنده آندروستان پایدار; AhR; aryl hydrocarbon receptor; EO; essential oil; EtOH; ethanol; CAR; constitutive androstane receptor; GR; glucocorticoid receptor; PXR; pregnane X receptor; RIF; rifampicin; VDR; vitamin D receptor; Food-drug interactions; Human hepatocytes; Essential
Liver lobe and strain differences in the activity of murine cytochrome P450 enzymes
Keywords: گیرنده آندروستان پایدار; Mouse; Cytochrome P450; Liver microsomes; Liver lobe differences; AhR; aryl hydrocarbon receptor; Alas1; delta-aminolevulinate synthase 1; BCA; bicinchoninic acid; BSA; bovine serum albumin; CAR; constitutive androstane receptor; CPR; cytochrome P450 redu
Short-chain chlorinated paraffins (SCCPs) induced thyroid disruption by enhancement of hepatic thyroid hormone influx and degradation in male Sprague Dawley rats
Keywords: گیرنده آندروستان پایدار; Short-chain chlorinated paraffins; Thyroid disruption; Hepatic metabolism; Thyroid hormone; Constitutive androstane receptor;
Comparison of the effects of sodium phenobarbital in wild type and humanized constitutive androstane receptor (CAR)/pregnane X receptor (PXR) mice and in cultured mouse, rat and human hepatocytes
Keywords: گیرنده آندروستان پایدار; Sodium phenobarbital; Constitutive androstane receptor; Pregnane X receptor; hCAR/hPXR mice; Cultured hepatocytes; Replicative DNA synthesis;
Galangin's potential as a functional food ingredient
Keywords: گیرنده آندروستان پایدار; Galangin; Propolis; Alpinia officinarum; Functional food ingredient; Polypharmacology; Flavonoid; AChE; acetylcholinesterase; AD; Alzheimer's disease; ADME; Administration, Distribution, Metabolism and Excretion; AHR; airway hyperresponsive; AhR; aryl h
Minimum datasets to establish a CAR-mediated mode of action for rodent liver tumors
Keywords: گیرنده آندروستان پایدار; CAR; Constitutive androstane receptor; Nitrapyrin; Metofluthrin; Rodent; Liver; Tumor; Mode of action; Minimal dataset; AOP; Adverse Outcome Pathway; AE; associative events; BrdU; 5-bromo-2â²-deoxyuridine; BROD; benzyloxyresorufin-O-debenzylation; BQ; be
Agonistic effects of diverse xenobiotics on the constitutive androstane receptor as detected in a recombinant yeast-cell assay
Keywords: گیرنده آندروستان پایدار; Constitutive androstane receptor; Alkyl phenol; Styrene dimer; Organochlorine; Bisphenol; Recombinant yeast;
From TCDD-mediated toxicity to searches of physiologic AHR functions
Keywords: گیرنده آندروستان پایدار; AHR; aryl hydrocarbon receptor; CAR; constitutive androstane receptor; PXR; pregnane-X-receptor; CYP; cytochrome P450; IDO1; indoleamine-2,3-dioxygenase; UDP; UDP-glucuronosyltransferase; FICZ; 6-formylindolo[3,2-b]carbazole; ICZ; indolo[3,2-b]carbazole;
Ubiquitination/sumoylation: An alternative pathway to modify gene regulation directed by xenosensors
Keywords: گیرنده آندروستان پایدار; Epigenetic regulation; Post-translational modifications; Nuclear receptors; Xenobiotics metabolism; AHR; aryl hydrocarbon receptor; AHRR; aryl hydrocarbon receptor repressor; ARNT; aryl hydrocarbon receptor nuclear translocator; CAR; constitutive androsta
Combination of CYP2C19 genotype with non-genetic factors evoking phenoconversion improves phenotype prediction
Keywords: گیرنده آندروستان پایدار; CAR; constitutive androstane receptor; CI; confidence interval; CYP; cytochrome P450; EM; extensive metabolizer; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GR; glucocorticoid receptor; IM; intermediate metabolizer; PCR; polymerase chain reaction; PM
Effect of amyloid beta on ATP-binding cassette transporter expression and activity in porcine brain microvascular endothelial cells
Keywords: گیرنده آندروستان پایدار; ABCB1; ABCG2; ABCC5; Nuclear receptors; Amyloid-β; Alzheimer's disease; Porcine brain endothelial cells; ABC; ATP-binding cassette; Aβ(1-42); amyloid-β (1-42); BBB; blood-brain barrier; CAR; constitutive androstane receptor; CAPS; 3-(Cyclohexylam
Characterization of CYP2C Induction in Cryopreserved Human Hepatocytes and Its Application in the Prediction of the Clinical Consequences of the Induction
Keywords: گیرنده آندروستان پایدار; cytochrome P450; mathematical models; hepatocytes; drug-drug interaction; induction; CAR; constitutive androstane receptor; CITIO; 6-(4-clorophenyl) imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime; P450; cytochrome P450; DDI; drug-d
E4bp4 regulates carboxylesterase 2 enzymes through repression of the nuclear receptor Rev-erbα in mice
Keywords: گیرنده آندروستان پایدار; bZip; the basic leucine zipper; CAR; constitutive androstane receptor; Ces/CES; mouse and human carboxylesterases; ChIP; chromatin immunoprecipitation assay; Co-IP; co-immunoprecipitation; CYP7A1; cholesterol 7alpha-hydroxylase; DMEM; Dulbecco's modifie
In vitro effect of mPEG2k-PCLx micelles on rat liver cytochrome P450 enzymes
Keywords: گیرنده آندروستان پایدار; Ahr; aryl hydrocarbon receptor; Car; constitutive androstane receptor; Pxr; pregnane X receptor; mPEG2k-PCLx micelles; Cytochrome P450 enzymes; Inhibition; Induction; Rat liver microsomes; Primary rat hepatocytes;
A review on the ethnomedicinal uses, phytochemistry and pharmacology of Alpinia officinarum Hance
Keywords: گیرنده آندروستان پایدار; ABS; Akaferd blood stopper; AN; Aspergillus niger; AO; Alpinia officinarum; BC; Bacillus cereus; B16-F10; Mouse melanoma cell line; CA; Candida albicans; CAR; Constitutive androstane receptor; CH2CL2; Dichloromethane; DPPH; Diphenylpicrylhydrazyl; EA; Eth
Aryl hydrocarbon receptor (AhR) mediated short-term effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on bile acid homeostasis in mice
Keywords: گیرنده آندروستان پایدار; Aryl hydrocarbon receptor; TCDD; Bile acids; Biliary excretion; Taurodeoxycholic acid; Cyp8b1; 1°BAs; Primary bile acids; 2°BAs; Secondary bile acids; 6-OH; 6-hydroxylated (6-OH); 12-OH; 12α-hydroxylated; Abc; ATP-binding cassette; AhR; Aryl hydrocarbo
Subchronic dietary exposure to ethoxyquin dimer induces microvesicular steatosis in male BALB/c mice
Keywords: گیرنده آندروستان پایدار; Food safety; Feed additives; Ethoxyquin; Hepatotoxicity; Benchmark dose; Multi-level omics; ADI; Acceptable Daily Intake; AIC; Akaike Information Criterion; ALT; Alanine transferase; AST; Aspartate transferase; BMD; Benchmark dose; BMDL; Lower bound bench
Natural products as modulators of the nuclear receptors and metabolic sensors LXR, FXR and RXR
Keywords: گیرنده آندروستان پایدار; Natural products; Nuclear receptors; Liver X receptor; Farnesoid X receptor; Retinoid X receptor; Metabolic syndrome; Precision medicine; 6-ECDCA; 6α-ethyl-chenodeoxycholic acid (obeticholic acid); AA; arachidonic acid; ABC; ATP-binding cassette transpor
Effect of carbamazepine on expression of UDP-glucuronosyltransferase 1A6 and 1A7 in rat brain
Keywords: گیرنده آندروستان پایدار; Uridine 5â²-diphosphate-glucuronosyltransferases; Carbamazepine; Brain; Induction; Constitutive androstane receptor;