دانلود مقالات ISI درباره سازنده فعال است + ترجمه فارسی

Rab20, a novel Rab small GTPase that negatively regulates neurite outgrowth of PC12 cells

Keywords: سازنده فعال است; CA; constitutively active; EE; early endosome; EGFP; enhanced green fluorescent protein; ER; endoplasmic reticulum; HRP; horseradish peroxidase; KD; knockdown; LE; late endosome; mStr; monomeric Strawberry; NGF; nerve growth factor; NS; not significant; P

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

p66Shc regulates migration of castration-resistant prostate cancer cells

Keywords: سازنده فعال است; Ab; antibody; ADT; androgen deprivation therapy; AI; androgen-independent; AR; androgen receptor; AS; androgen-sensitive; CA; constitutively active; cPAcP; cellular prostatic acid phosphatase; CR PCa; castration-resistant prostate cancer; DHT; 5α‑dihyd

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

RhoA GTPase oxidation stimulates cell proliferation via nuclear factor-κB activation

Keywords: سازنده فعال است; CA; constitutively active; DMEM; Dulbecco's modified Eagle's medium; DN; dominant negative; GAP; GTPase activating protein; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GDF; GDI displacement factor; GDI; guanine nucleotide dissociation inhibitor; GEF;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Tyr42 phosphorylation of RhoA GTPase promotes tumorigenesis through nuclear factor (NF)-κB

Keywords: سازنده فعال است; CA; constitutively active; DMEM; Dulbecco's modified Eagle's medium; DN; dominant negative; GAP; GTPase activating protein; GDF; GDI displacement factor; GDI; guanine nucleotide dissociation inhibitor; GEF; guanine nucleotide exchange factor; GSH; glutath

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

Common pathways regulate Type III TGFβ receptor-dependent cell invasion in epicardial and endocardial cells

Keywords: سازنده فعال است; βArr2; beta-arrestin2; ALK; activin receptor-like kinases; AV; atrioventricular; BMP; bone morphogenetic protein; ca; constitutively active; EMT; Epithelial-Mesenchymal Transformation; FGF; fibroblast growth factor; GFP; green fluorescent protein; GIPC

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Vav1 increases Bcl-2 expression by selective activation of Rac2-Akt in leukemia T cells

Keywords: سازنده فعال است; GEF; guanine nucleotide exchange factor; T-CVID; T cell type common variable immunodeficiency; B-CLL; B-cell chronic lymphocytic leukemia; shRNA; short-hairpin RNA; SDS-PAGE; SDS-polyacrylamide gel electrophoresis; GST; Glutathione S-transferase; PAK1; p2

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Classical NF-κB activation impairs skeletal muscle oxidative phenotype by reducing IKK-α expression

Keywords: سازنده فعال است; ACTB; Beta Cytoskeletal Actin; ALAS1; Delta-aminolevulinate synthase 1; ATP; Adenosine triphosphate; Ad; Adenoviral; B2M; β2m, Beta 2 microglobulin; BMI; Body mass index; COPD; Chronic obstructive pulmonary disease; CA; Constitutively active; COXIV; Cyto

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Crosstalk between mitogen-activated protein kinases and mitochondria in cardiac diseases: Therapeutic perspectives

Keywords: سازنده فعال است; Heart; MAPK; Cardiac diseases; Mitochondria; Cell signaling; AngII; angiotensin II; CA; constitutively active; CHIP; C terminus of Hsc70-interacting protein; CT-1; cardiotrophin-1; ΔΨmit; mitochondrial membrane potential; DN; dominant negative; ERK1/2;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2014 سفارش ترجمه

Regulated in DNA damage and development 1 (REDD1) promotes cell survival during serum deprivation by sustaining repression of signaling through the mechanistic target of rapamycin in complex 1 (mTORC1)

Keywords: سازنده فعال است; 4E-BP1; eukaryotic initiation factor 4E binding protein 1; ATF4; activating transcription factor 4; ca; constitutively active; dn; dominant negative; ERK; extracellular signal-related protein kinase; FBS; fetal bovine serum; GCN2; general control non-dere

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Rit subfamily small GTPases: Regulators in neuronal differentiation and survival

Keywords: سازنده فعال است; CA; constitutively active; cAMP; cyclic adenosine monophosphate; CaM; calmodulin; CCI; controlled cortical impact; CREB; cAMP response element binding protein; CRIB; Cdc42/Rac interactive binding; DA; dopamine; DAT; dopamine transporter; DN; dominant nega

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

The Drosophila larva as a tool to study gut-associated macrophages: PI3K regulates a discrete hemocyte population at the proventriculus

Keywords: سازنده فعال است; Haemocyte; Gut; Intestine; Innate immunity; Insect; Migration; Phagocytosis; PV; proventriculus; L3W; L3 wandering larvae; DH31; diuretic hormone 31; PI3K; phosphoinositide 3-kinase; DN; dominant negative; CA; constitutively active;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Identification and functional characterization of polo-like kinase 2 autoregulatory sites

Keywords: سازنده فعال است; Plk2; SNK; homeostatic plasticity; polo kinase; posttranslational modification; CA; constitutively active; CaMPDB; Calpain for Modulatory Proteolysis Database; DIV; days in vitro; GFP; green fluorescent protein; KD; kinase-dead; LC-MS/MS; liquid chromatog

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Suppression of FAT/CD36 mRNA by human growth hormone in pancreatic β-cells

Keywords: سازنده فعال است; CA; constitutively active; DN; dominant negative; FA; fatty acid; GSIS; glucose-stimulated insulin secretion; FATP; fatty acid transport protein; FABP; fatty acid binding protein; FASN; fatty acid synthase; FAT; fatty acid translocase; GFP; green fluoresc

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Ablation of p21-activated kinase-1 in mice promotes isoproterenol-induced cardiac hypertrophy in association with activation of Erk1/2 and inhibition of protein phosphatase 2A

Keywords: سازنده فعال است; 2-D DIGE; 2-D Difference In Gel Electrophoresis; CA; constitutively active; cTnI; cardiac troponin I; cTnT; cardiac troponin T; CTRL; control; EDT; transmitral early filling deceleration time; EDV; end-diastolic volume; Erk; extracellular signal-regulated

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Recent progress toward understanding the molecular mechanisms that regulate skeletal muscle mass

Keywords: سازنده فعال است; 4E-BP1; 4E binding protein 1; 5′UTR; 5′ untranslated region; AICAR; 5-aminoimidazole-4-carboxamide riboside; AMP; adenosine monophosphate; AMPK; 5′-AMP-activated protein kinase; AMPK α1−/−; AMPK α1 subunit knockout; AMPKα1−/−α2−/−; A

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

ATF6 is important under both pathological and physiological states in the heart

Keywords: سازنده فعال است; ER stress; ATF6; AEBSF; Transgenic mice; Myocardial infarction; Dominant negative; Constitutively active; Apoptosis; Bcl-2;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Kindlin-2 phosphorylation by Src at Y193 enhances Src activity and is involved in Migfilin recruitment to the focal adhesions

Keywords: سازنده فعال است; WT; wild type; KD; kinase dead; CA; constitutively active; ECM; extracellular matrix; Src; Kindlin-2; Migfilin; Tyrosine phosphorylation; Focal adhesion;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Enhanced Resistance to Tamoxifen by the c-ABL Proto-oncogene in Breast Cancer

Keywords: سازنده فعال است; ERα; estrogen receptor α; ERE; estrogen receptor response element; WT; wild-type; kd; kinase-deficient; CA; constitutively active; TAM; tamoxifen; shLuc; short hairpin RNA against luciferase; shABL; short hairpin RNA against c-ABL;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Characterization of a dominant-active STAT that promotes tumorigenesis in Drosophila

Keywords: سازنده فعال است; STAT; JAK; Unpaired; Drosophila; Constitutively active; In vitro reporter; In vivo reporter; Structure function; Signal transduction

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2010 سفارش ترجمه

Conformational induction is the key process for activation of the AT1 receptor

Keywords: سازنده فعال است; AT1 receptor; Constitutively active; Extended ternary complex model; Conformational selection; Conformational induction

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Role of specific protein kinase C isoforms in modulation of β1- and β2-adrenergic receptors

Keywords: سازنده فعال است; Signalling; G protein-coupled receptors; Desensitization; Protein kinase; α1BAR; α1B-adrenergic receptor; CA; constitutively active; CYP; cyanopindolol; βAR; β-adrenergic receptor; βARK; β-adrenergic receptor kinase; GPCR; G protein-coupled receptor

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Inhibition of insulin/IGF-1 receptor signaling enhances bile acid toxicity in primary hepatocytes

Keywords: سازنده فعال است; AG; AG1478; ASM; acidic sphingomyelinase; ca; constitutively active; CD533; dominant negative ERBB1; DCA; deoxycholic acid; dn; dominant negative; EGF; epidermal growth factor; ERK; extracellular regulated kinase; FADD; FAS associating death domain protei

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

PKB mediates c-erbB2-induced epithelial β1 integrin conformational inactivation through Rho-independent F-actin rearrangements

Keywords: سازنده فعال است; ca; constitutively active; dn; dominant-negative; ERK; extracellular signal-regulated kinase; GFP; green fluorescent protein; GST; glutathione-S-transferase; ILK; integrin-linked kinase; LPA; lysophosphatidic acid; LTB; latrunculin B; mDia; mammalian ho

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2005 سفارش ترجمه