Keywords: DNA متصل به جنس مخالف بسته شده است; AFM; atomic force microscopy; ATR; Attenuated total reflectance (IR system); CCC; covalently closed circular DNA; CD; circular dichroism; CT DNA; calf thymus DNA; DEPT; distortionless enhancement by polarization transfer; DMF; Dimethylformamide; DMSO; Dim
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Keywords: DNA متصل به جنس مخالف بسته شده است; AASLD; American Association for the Study of the Liver Disease; AFP; α-fetoprotein; ALT; alanine aminotransferase; AST; aspartase aminotransferase; AFP-L3; agglutinin reactive fraction of AFP; cccDNA; covalently closed circular DNA; CTL; cytotoxic T lymp
Keywords: DNA متصل به جنس مخالف بسته شده است; AIDS; acquired immune deficiency syndrome; ALV; avian leukosis virus; AMV; avian myeloblastosis virus; APOBEC; apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like; ASLV; avian sarcoma leukosis virus; AZT; 3â² -azido-3â² -deoxythymidine; BIV;
Keywords: DNA متصل به جنس مخالف بسته شده است; Hepatitis B; Guidelines; Antiviral Therapy; Peginterferon alfa-2a; Entecavir; Tenofovir; Resistance; AFP; alpha-fetoprotein; ALT; alanine aminotransferase; anti-HBc; antibody to hepatitis B core antigen; anti-HBe; antibody to hepatitis B e antigen; anti-H
Viral Hepatitis: Knowledge and Treatments for Hepatitis B and C Virus and Associated Transplantation and Neoplasia
Keywords: DNA متصل به جنس مخالف بسته شده است; cccDNA; covalently closed circular DNA; HBV; hepatitis B virus; HCV; hepatitis C virus;
Tumor suppressor ZHX2 restricts hepatitis B virus replication via epigenetic and non-epigenetic manners
Keywords: DNA متصل به جنس مخالف بسته شده است; HBV cccDNA; Transcription factor; Epigenetic regulation; ZHX2; Zinc finger and homeoboxes 2; HBV; hepatitis B virus; cccDNA; covalently closed circular DNA; HBeAg; hepatitis B e antigen; HBsAg; hepatitis B surface antigen; HBcAg; hepatitis B core antigen;
The potential and challenges of CRISPR-Cas in eradication of hepatitis B virus covalently closed circular DNA
Keywords: DNA متصل به جنس مخالف بسته شده است; CHB; chronic hepatitis B; HBV; hepatitis B virus; NA; nucleos(t)ide analogue; cccDNA; covalently closed circular DNA; guide RNA; gRNA; NTCP; sodium taurocholate cotransporting polypeptide; RC-DNA; relaxed circular DNA; pgRNA; pregenomic RNAs; HBsAg; HBV s
Efficacy of NVR 3-778, Alone and In Combination With Pegylated Interferon, vs Entecavir In uPA/SCID Mice With Humanized Livers and HBV Infection
Keywords: DNA متصل به جنس مخالف بسته شده است; CAM; ER Stress Response; Assembly Inhibitor Core Protein; Replication; DAA; ALT; alanine aminotransferase; CAM; capsid assembly modulator; cccDNA; covalently closed circular DNA; ER; endoplasmatic reticulum; ETV; entecavir; h-Alb; human albumin; HAP; hete
Deep sequencing identifies hepatitis B virus core protein signatures in chronic hepatitis B patients
Keywords: DNA متصل به جنس مخالف بسته شده است; Hepatitis B virus core protein; Chronic hepatitis B; Deep sequencing; HBeAg status; Treatment response; HBV; hepatitis B virus; CHB; chronic hepatitis B; NUC; nucleos(t)ide analogues; peg-IFN; pegylated interferon; HBsAg; hepatitis B surface antigen; HBc;
Nonlytic Lymphocytes Engineered to Express Virus-Specific T-Cell Receptors Limit HBV Infection by Activating APOBEC3
Keywords: DNA متصل به جنس مخالف بسته شده است; Antiviral; Immune Response; Immune Therapy; LTB; 3-D; 3-dimensional; AE-T; activated T; APOBEC3; apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3; CAR; chimeric antigen receptor; cccDNA; covalently closed circular DNA; E:T; effector cell-to
INASL Position Statements on Prevention, Diagnosis and Management of Hepatitis B Virus Infection in India: The Andaman Statements
Keywords: DNA متصل به جنس مخالف بسته شده است; AASLD; American Association for the Study of Liver Diseases; ADV; adefovir dipivoxil; ALT; alanine aminotransferase; Anti-HBe; antibodies to hepatitis B envelope antigen; anti-HBs; antibody to hepatitis B surface antigen; APASL; Asian Pacific Association
HBV Bypasses the Innate Immune Response and Does Not Protect HCV From Antiviral Activity of Interferon
Keywords: DNA متصل به جنس مخالف بسته شده است; Coinfection; Interferon-stimulated Gene; PRR; RIG-I; APOBEC; apolipoprotein B mRNA editing enzyme catalytic subunit; cccDNA; covalently closed circular DNA; CHB; chronic hepatitis B; circDNA; circular DNA; GFP-IRF3; green fluorescent protein-interferon
Humanized chimeric mouse models of hepatitis B virus infection
Keywords: DNA متصل به جنس مخالف بسته شده است; HBV; hepatitis B virus; cccDNA; covalently closed circular DNA; SCID; severe combined immunodeficiency; alb-uPA; albumin-promoted urokinase-type plasminogen activator; RAG2; recombinant activation gene 2; RI; repopulation index; FAH; fumarylacetoacetate h
Detection of the hepatitis B virus (HBV) covalently-closed-circular DNA (cccDNA) in mice transduced with a recombinant AAV-HBV vector
Keywords: DNA متصل به جنس مخالف بسته شده است; Hepatitis B virus; cccDNA; Adeno-associated virus; Immune-competent mouse; Immune-therapeutics; AAV; adeno-associated virus; cccDNA; covalently closed circular DNA; DIG; digoxigenin; dsl; double stranded linear DNA; HBV; Hepatitis B Virus; HDV; Hepatitis
Animal models of HBV infection
Keywords: DNA متصل به جنس مخالف بسته شده است; Animal models; HBV-related viruses; Hepadnaviruses; Humanized mice; Antiviral therapy; Immunopathogenesis; HBV; hepatitis B virus; cccDNA; covalently closed circular DNA; pgRNA; pregenomic RNA; DHBV; duck hepatitis B virus; WHV; woodchuck hepatitis virus;
Impact of hepatitis B vaccination on HBsAg kinetics, interferon-inducible protein 10 level and recurrence of viremia
Keywords: DNA متصل به جنس مخالف بسته شده است; CccDNA; covalently closed circular DNA; CHB; chronic hepatitis B; ECLIA; Electrochemiluminescence immunoassay; ELISA; Enzyme-linked immunosorbent assay; HBsAg; HBV surface antigen; HCC; hepatocellular carcinoma; HOMA-IR; Homeostatic model assessment for i
Role of hepatitis B core protein in HBV transcription and recruitment of histone acetyltransferases to cccDNA minichromosome
Keywords: DNA متصل به جنس مخالف بسته شده است; Hepatitis B virus; Hepatitis B core protein; HBV transcription; Histone acetylation; Covalently closed circular DNA; HBV; hepatitis B virus; cccDNA; covalently closed circular DNA; HBc; hepatitis B core protein; CTD; C-terminal domain; pgRNA; pregenomic R
Viral minority variants in the core promoter and precore region identified by deep sequencing are associated with response to peginterferon and adefovir in HBeAg negative chronic hepatitis B patients
Keywords: DNA متصل به جنس مخالف بسته شده است; Peginterferon alfa-2a; Adefovir; Ultra-deep pyrosequencing; Mutation; Hepatitis B e antigen; Response marker; 454 DS; 454 deep sequencing; ALT; alanine aminotransferase; BCP; basal core promoter; cccDNA; covalently closed circular DNA; CHB; chronic hepati
Hepatitis B cure: From discovery to regulatory approval
Keywords: DNA متصل به جنس مخالف بسته شده است; Chronic hepatitis B; Antiviral therapy; Immune modulatory therapy; Hepatitis B surface antigen; Covalently closed circular DNA;
Hepatitis B Virus Activates Signal Transducer and Activator of Transcription 3 Supporting Hepatocyte Survival and Virus Replication
Keywords: DNA متصل به جنس مخالف بسته شده است; Hepatitis B Virus Infection; STAT3 Signaling; Hepatocellular Carcinoma; Apoptosis; APR; acute phase response; cDNA; complementary DNA; cccDNA; covalently closed circular DNA; cRNA; complementary RNA; CRP; C-reactive protein; DMSO; dimethyl sulfoxide; FCS;
Altered expression of interferon-stimulated genes is strongly associated with therapeutic outcomes in hepatitis B virus infection
Keywords: DNA متصل به جنس مخالف بسته شده است; Chronic hepatitis B; Antiviral therapy; IFN signaling pathway; STAT1; MX; Peg-IFN; pegylated interferon; HBeAg; hepatitis B e antigen; HBsAg; hepatitis B surface antigen; NAs; nucleot(s)ide analogues; CHB; chronic hepatitis B; ETV; entecavir; ISGs; interf
Viral Load Affects the Immune Response to HBV in Mice With Humanized Immune System and Liver
Keywords: DNA متصل به جنس مخالف بسته شده است; NK Cell; CXCL10; Mouse Model; IL10; HBe; cccDNA; covalently closed circular DNA; CHB; chronically HBV infected; ELISA; enzyme-Linked Immunosorbent Assay; ETV; entecavir; hAlb; human Albumin; HBcAg; hepatitis B core antigen; HBe; hepatitis B envelope; HBs;
Exploring the potential of genome editing CRISPR-Cas9 technology
Keywords: DNA متصل به جنس مخالف بسته شده است; Cas; CRISPR-associated proteins; cccDNA; covalently closed circular DNA; CCR5; C-C chemokine receptor type 5; CHO; Chinese hamster ovary; CRISPRs; clustered regularly interspaced short palindromic repeats; CRISPRa; CRISPR activation; CRISPRi; CRISPR inter
Two-way molecular ligation for efficient conversion of monomeric hepatitis B virus DNA constructs into tandem dimers
Keywords: DNA متصل به جنس مخالف بسته شده است; cccDNA; covalently closed circular DNA; HBeAg; hepatitis B e antigen; HBsAg; hepatitis B surface antigen; HBV; hepatitis B virus; HCC; hepatocellular carcinoma; pg RNA; pregenomic RNA; Hepatitis B virus; Covalently closed circular DNA; Tandem dimer; Prege
Quantitative intrahepatic HBV cccDNA correlates with histological liver inflammation in chronic hepatitis B virus infection
Keywords: DNA متصل به جنس مخالف بسته شده است; Hepatitis B virus; Covalently closed circular DNA; Rolling circle amplification; Histological liver inflammation;
Research ArticleNovel pH-sensitive multifunctional envelope-type nanodevice for siRNA-based treatments for chronic HBV infection
Keywords: DNA متصل به جنس مخالف بسته شده است; HBV; hepatitis B virus; ETV; entecavir; MEND; pH-sensitive multifunctional envelope-type nanodevice; cccDNA; covalently closed circular DNA; HBsAg; hepatitis B virus surface antigen; HBeAg; hepatitis B virus e antigen; HBcAg; hepatitis B virus core antige
Original ResearchFull Report: Basic and Translational-LiverInterferon-γ and Tumor Necrosis Factor-α Produced by T Cells Reduce the HBV Persistence Form, cccDNA, Without Cytolysis
Keywords: DNA متصل به جنس مخالف بسته شده است; Apolipoprotein B mRNA Editing Enzyme; HBV Persistence; T-Cell Receptor; Immune Regulation; 3D-PCR; differential DNA denaturation PCR; A3; APOBEC3; ALT; alanine aminotransferase; AP; apurinic/apyrimidinic; cccDNA; covalently closed circular DNA; Cp; crossi
Suppression of hepatitis B virus antigen production and replication by wild-type HBV dependently replicating HBV shRNA vectors in vitro and in vivo
Keywords: DNA متصل به جنس مخالف بسته شده است; Hepatitis B virus; HBV vector; RNAi; Chronic hepatitis B; HBV transgenic mice; shRNA delivery; HBV; hepatitis B virus; cccDNA; covalently closed circular DNA; CMV-IE; cytomegalovirus immediate early; dsL; double-stranded linear; FACS; fluorescence-activat
Intrahepatic hepatitis B virus replication and liver histology in subjects with occult hepatitis B infection
Keywords: DNA متصل به جنس مخالف بسته شده است; Covalently closed circular DNA; hepatitis B virus replication; intrahepatic hepatitis B virus DNA; liver histology; occult hepatitis B infection;
Hepatitis B virus (HBV) X protein-mediated regulation of hepatocyte metabolic pathways affects viral replication
Keywords: DNA متصل به جنس مخالف بسته شده است; HBV; Hepatitis B virus; HCC; Hepatocellular carcinoma; HBx; HBV X protein; cccDNA; Covalently closed circular DNA; ORF; Open reading frame; mTORC1; Mammalian target of rapamycin (mTOR) complex 1; TSC2; Tuberous-sclerosis complex-2; AMPK; AMP-activated pro
Advances in therapeutic CRISPR/Cas9 genome editing
Keywords: DNA متصل به جنس مخالف بسته شده است; Cas9; CRISPR-associated protein 9; cccDNA; covalently closed circular DNA; CCR5; chemokine receptor 5; CFTR; cystic fibrosis transmembrane conductance regulator; CRISPRs; clustered regularly interspaced short palindromic repeats; crRNA; CRISPR RNA; Crygc;
Hepatitis B virus basal core promoter mutations show lower replication fitness associated with cccDNA acetylation status
Keywords: DNA متصل به جنس مخالف بسته شده است; BCP; basal core promoter; CHB; chronic HBV; cccDNA; covalently closed circular DNA; DNMT; DNA methyltransferases; DS DNA; double stranded DNA; HATs; histone acetyltransferases; HDAC1; class 1 histone deacetylase; OC DNA; open circular DNA; ORFs; open read
HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant
Keywords: DNA متصل به جنس مخالف بسته شده است; HBsAg; Antiviral Immunity; HBV Replication; Hepatocyte Proliferation; AASLD; American Association for the Study of Liver Diseases; ALT; alanine aminotransferase; cccDNA; covalently closed circular DNA; CHB; chronic hepatitis B; EASL; European Association
Serum microRNA-210 levels in different groups of chronic hepatitis B patients
Keywords: DNA متصل به جنس مخالف بسته شده است; MicroRNA-210; HBV carrier; HBV DNA; HBs antigen; Chronic hepatitis B; HBV; hepatitis B virus,; CHB; chronic hepatitis B; HCC; hepatocellular carcinoma; miRNA; microRNA; HAI; histological activity index; ALT; alanine aminotransferase; INR; international no
Clinical Events After Cessation of Lamivudine Therapy in Patients Recovered From Hepatitis B Flare With Hepatic Decompensation
Keywords: DNA متصل به جنس مخالف بسته شده است; Antiviral Therapy; Cirrhosis; Liver Cancer; Nucleos(t)ide Analog; ADV; adefovir; AFP; alpha fetoprotein; ALT; alanine aminotransferase; anti-HBe; hepatitis B e antibody; cccDNA; covalently closed circular DNA; CHB; chronic hepatitis B; δPT; prolongation
Research ArticleQuantification of HBsAg in nucleos(t)ide-naïve patients treated for chronic hepatitis B with entecavir with or without tenofovir in the BE-LOW study
Keywords: DNA متصل به جنس مخالف بسته شده است; CHB; chronic hepatitis B; HBV; hepatitis B virus; HCC; hepatocellular carcinoma; cccDNA; covalently closed circular DNA; HBsAg; hepatitis B surface antigen; peg-IFN; pegylated interferon; HBeAg; hepatitis B e antigen; ETV; entecavir; TDF; tenofovir disopr
Interleukin 6 inhibits HBV entry through NTCP down regulation
Keywords: DNA متصل به جنس مخالف بسته شده است; HBV; Hepatitis B virus; NTCP; Sodium taurocholate co-transporting polypeptide; IL-6; Interleukin 6; IFN γ; Interferon gamma; ALT; Alanine aminotransferase; TNFα; Tumor Necrosis Factor alpha; IL-1β; Interleukin 1 beta; OSM; Oncostatin M; PHH; Primary Hu
Hepatitis B virus DNA quantification with the three-in-one (3io) method allows accurate single-step differentiation of total HBV DNA and cccDNA in biopsy-size liver samples
Keywords: DNA متصل به جنس مخالف بسته شده است; ALT; alanine transaminase; cccDNA; covalently closed circular DNA; FFPE tissue; formalin-fixed, paraffin-embedded tissue; gDNA; genomic DNA; hACTB; human β-actin gene; HBeAg; hepatitis B e antigen; HBsAg; hepatits B surface antigen; HBV; hepatitis B viru
Research ArticlePersistent hepatitis D virus mono-infection in humanized mice is efficiently converted by hepatitis B virus to a productive co-infection
Keywords: DNA متصل به جنس مخالف بسته شده است; HDV; hepatitis delta virus; HBV; hepatitis B virus; cccDNA; covalently closed circular DNA; HBsAg; HBV surface antigen; HBcAg; HBV core antigen; HDAg; hepatitis delta antigen; USB; uPA/SCID beige mice; HDV mono-infection; HDAg; HBV super-infection; Human
Research ArticleHBsAg loss in patients treated with peginterferon alfa-2a and adefovir is associated with SLC16A9 gene variation and lower plasma carnitine levels
Keywords: DNA متصل به جنس مخالف بسته شده است; ALT; alanine aminotransferase; cccDNA; covalently closed circular DNA; CD8+; cluster of differentiation 8 positive; CHB; chronic hepatitis B; CR; combined response; FACS; fluorescent activated cell sorter; GWAS; genome-wide association study; HBeAg; hepat
Modeling the effects of covalently closed circular DNA and dendritic cells in chronic HBV infection
Keywords: DNA متصل به جنس مخالف بسته شده است; HBV; Hepatitis B virus; CccDNA; Covalently closed circular DNA; DCs; Dendritic cells; IFN; Interferon alpha; NAs; Nucleoside/nucleotide analogs; APCs; Antigen-presenting cells; CTL; Cytotoxic T lymphocyte; Th1; Helper T cell 1; HBsAg; HBV surface antigen;
ReviewHepatitis B flares in chronic hepatitis B: Pathogenesis, natural course, and management
Keywords: DNA متصل به جنس مخالف بسته شده است; ADV; adefovir; AFP; alphafetoprotein; ALT; alanine aminotransferase; anti-CD20; CD20 antibodies; anti-TNF; anti-tumour necrosis factors; ART; antiretroviral therapy; BHN; bridging hepatic necrosis; cccDNA; covalently closed circular DNA; CHB; chronic hepa
Hepatitis B and D Viruses Exploit Sodium Taurocholate Co-transporting Polypeptide for Species-Specific Entry into Hepatocytes
Keywords: DNA متصل به جنس مخالف بسته شده است; Species Specificity; Virology; Virus Entry; Myrcludex B; cccDNA; covalently closed circular DNA; DMSO; dimethyl sulfoxide; h; human; HBcAg; hepatitis B core antigen; HBeAg; hepatitis B e antigen; HBsAg; hepatitis B surface antigen; HBV; hepatitis B virus;
Short hairpin RNA induces methylation of hepatitis B virus covalently closed circular DNA in human hepatoma cells
Keywords: DNA متصل به جنس مخالف بسته شده است; cccDNA; covalently closed circular DNA; HBV; hepatitis B virus; siRNA; small interfering RNA; shRNA; short hairpin RNA; PTGS; post-transcriptional gene silencing; RdDM; RNA dependent DNA methylation; RNAi; RNA interference; TGS; transcriptional gene silen
Concerted action of activation-induced cytidine deaminase and uracil-DNA glycosylase reduces covalently closed circular DNA of duck hepatitis B virus
Keywords: DNA متصل به جنس مخالف بسته شده است; AID; activation-induced cytidine deaminase; APOBEC; apolipoprotein B mRNA-editing enzyme catalytic subunit; UNG; uracil-DNA glycosylase; DHBV; duck hepatitis B virus; cccDNA; covalently closed circular DNA; 3D-PCR; differential denaturation DNA PCR; AID;
Research ArticleThe entry inhibitor Myrcludex-B efficiently blocks intrahepatic virus spreading in humanized mice previously infected with hepatitis B virus
Keywords: DNA متصل به جنس مخالف بسته شده است; IFN; interferon; HBV; hepatitis B virus; pgRNA; pregenomic RNA; cccDNA; covalently closed circular DNA; rcDNA; relaxed circular DNA; HBV; uPA; Humanized mice; Entry inhibitor; cccDNA;
Research ArticleLong-term hepatitis B surface antigen (HBsAg) kinetics during nucleoside/nucleotide analogue therapy: Finite treatment duration unlikely
Keywords: DNA متصل به جنس مخالف بسته شده است; HBV; hepatitis B virus; HBsAg; hepatitis B surface antigen; cccDNA; covalently closed circular DNA; HBeAg; hepatitis B e antigen; IFN; interferon; IU; international unit; HDV; hepatitis D virus; PCR; polymerase chain reaction; IQR; interquartile range; He
Original ResearchFull Report: Basic and Translational-LiverT Cells Expressing a Chimeric Antigen Receptor That Binds Hepatitis BÂ Virus Envelope Proteins Control Virus Replication in Mice
Keywords: DNA متصل به جنس مخالف بسته شده است; Immunotherapy; Chronic Hepatitis B; Hepatocellular Carcinoma; Adoptive T-Cell Therapy; ALT; alanine aminotransferase; CAR; chimeric antigen receptor; cccDNA; covalently closed circular DNA; CEA; carcinoembryonic antigen; DC; dendritic cells; HBsAg; hepati
Reduction of Hepatitis B Surface Antigen and Covalently Closed Circular DNA by Nucleos(t)ide Analogues of Different Potency
Keywords: DNA متصل به جنس مخالف بسته شده است; Antiviral Therapy; Viral Hepatitis; Response to Therapy; Prognosis; cccDNA; covalently closed circular DNA; CHB; chronic hepatitis B; HBeAg; hepatitis B e antigen; HBV; hepatitis B virus; NA; nucleos(t)ide analogue; qHBsAg; quantitative hepatitis B surfac
Research ArticleDecreased infectivity of nucleoside analogs-resistant hepatitis B virus mutants
Keywords: DNA متصل به جنس مخالف بسته شده است; HBV; hepatitis B virus; RT; reverse transcriptase; S; surface; HDV; hepatitis delta virus; PCR; polymerase chain reaction; WT; wild type; ORF; open reading frame; Ag; antigen; SVP; subviral particle; cccDNA; covalently closed circular DNA; HBV; Nucleos(t)