Keywords: COX، Cyclo-Oxygenase; ASIC3, Acid-sensing ion channel 3; BDNF, Brain-derived neurotrophic factor; BMP, Bone morphogenetic proteins; CGRP, Calcitonin gene-related peptide; COX, Cyclo-oxygenase; CRPS, Complex Regional Pain Syndrome; DRG, Dorsal root ganglia; GAP43, Growth-associ
مقالات ISI COX، Cyclo-Oxygenase (ترجمه نشده)
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Keywords: COX، Cyclo-Oxygenase; Tooth extraction; exodontia; antiplatelet; aspirin; NSAID; thienopyridine; clopidogrel; dipyridamole; postoperative bleedingADP, Adenosine diphosphate; COX, Cyclo-oxygenase; DES, Drug-eluting stent; GP, Glycoprotein; NSAID, Nonsteroidal anti-inflammatory
Keywords: COX، Cyclo-Oxygenase; BH4, tetrahydrobiopterin; CRP, C-reactive protein; COX, cyclo-oxygenase; ER, endoplasmic reticulum; ERO1, endoplasmic reticulum oxidoreductin 1; EV, extracellular vesicles; FX1, factor XI; GPI, glycoprotein 1; GPX, glutathione peroxidase; GRX, glutaredoxi
Keywords: COX، Cyclo-Oxygenase; COX, cyclo-oxygenase; DCFH-DA, dichlorofluorescein diacetate; DMEM, Dulbecco’s minimum essential media; DMSO, dimethyl sulfoxide; DPI, diphenylene iodonium; FBS, fetal bovine serum; IL-6, interleukin-6; l-NAME, l-NG-nitroarginine methyl ester; LPS, lipopo
Keywords: COX، Cyclo-Oxygenase; ANF, anidulafungin; ASA, aspirin; COX, cyclo-oxygenase; DFCN, diclofenac; DMSO, dimethyl sulfoxide; DO, optical density; ECs, echinocandins; FIC, fractional inhibitory concentration; FICI, fractional inhibitory concentration indice; IBF, ibuprofen; MIC, m
Gastroprotective effects of thymol on acute and chronic ulcers in rats: The role of prostaglandins, ATP-sensitive K+ channels, and gastric mucus secretion
Keywords: COX، Cyclo-Oxygenase; Gastric ulcer; Gastroprotection; ATP-Sensitive K+ channels; Prostaglandins; ThymolCBS, cystathionine-β-synthetase; COX, cyclo-oxygenase; CSE, cystathionine-γ-lyase; eNOS, endothelial NOS; Glib, glibenclamide; GSH, glutathione; HE, hematoxylin-eosin; H2S,
Epigallocatechin gallate (EGCG) suppresses lipopolysaccharide-induced inflammatory bone resorption, and protects against alveolar bone loss in mice
Keywords: COX، Cyclo-Oxygenase; BMN, bone mineral density; COX, cyclo-oxygenase; EGCG, (−)-epigallocatechin-3-gallate; LPS, lipopolysaccharide; mPGES, membrane-bound PGE synthase; OCPC, o-cresolphthalein complexon; OPG, osteoprotegerin; PGE2, prostaglandin E2; PSD, polymicrobial synergy
Effect of Ocimum basilicum L. on cyclo-oxygenase isoforms and prostaglandins involved in thrombosis
Keywords: COX، Cyclo-Oxygenase; 6-ketoPGF1α, 6-keto-prostaglandin F1α; AA, arachidonic acid; ADP, adenosine diphosphate; ANOVA, analysis of variance; ASA, aspirin; B, butanol; C, chloroform; CCTCC, Wuhan University Cell Bank; COX, cyclo-oxygenase; E, ethanol; EA, ethylacetate; FBS, feta
Synthesis and structure–activity relationships for 1-(4-(piperidin-1-ylsulfonyl)phenyl)pyrrolidin-2-ones as novel non-carboxylate inhibitors of the aldo-keto reductase enzyme AKR1C3
Keywords: COX، Cyclo-Oxygenase; Aldo-keto reductase; Inhibitor; Crystal structure; Computer aided drug designAKR, aldo-keto reductase; COX, cyclo-oxygenase; DCM, dichloromethane; DMSO, dimethyl sulfoxide; NADPH, nicotinamide adenine dinucleotide phosphate; NSAID, non-steroidal anti-infl
Structure, DNA- and albumin-binding of the manganese(II) complex with the non-steroidal antiinflammatory drug niflumic acid
Keywords: COX، Cyclo-Oxygenase; bipy, 2,2′-bipyridine; CT, calf-thymus; bipyam, 2,2′-bipyridylamine; BSA, bovine serum albumin; COX, cyclo-oxygenase; DMF, N,N-dimethylformamide; DMSO, dimethylsulfoxide; EB, ethidium bromide, 3,8-diamino-5-ethyl-6-phenyl-phenanthridinium bromide; Hnif, n
Association between traditional systemic antipsoriatic drugs and tuberculosis risk in patients with psoriasis with or without psoriatic arthritis: Results of a nationwide cohort study from Taiwan
Keywords: COX، Cyclo-Oxygenase; antipsoriatic drugs; association; psoriasis; traditional systemic; tuberculosisCI, confidence interval; COX, cyclo-oxygenase; EPTB, extrapulmonary tuberculosis; ICD-9-CM, International Classification of Diseases, Ninth Revision, Clinical Modification; IFN
Pathobiology of actinic keratosis: Ultraviolet-dependent keratinocyte proliferation
Keywords: COX، Cyclo-Oxygenase; actinic keratosis; apoptosis; immunosuppression; keratinocyte carcinogenesis; p53AK, actinic keratosis; BRG1, brahma-related gene 1; BRM, brahma; COX, cyclo-oxygenase; EGFR, epidermal growth factor receptor; Foxp3, forkhead box p3; HPV, human papillomavir
Ni(II) complexes with non-steroidal anti-inflammatory drug diclofenac: Structure and interaction with DNA and albumins
Keywords: COX، Cyclo-Oxygenase; Bipy, 2,2′-bipyridine; BSA, bovine serum albumin; COX, cyclo-oxygenase; CT, calf-thymus; DMF, N,N-dimethylformamide; EB, ethidium bromide, 3,8-diamino-5-ethyl-6-phenyl-phenanthridinium bromide; HSA, human serum albumin; Nadicl, sodium diclofenac, sodium 2
Anopheline anti-platelet protein from a malaria vector mosquito has anti-thrombotic effects in vivo without compromising hemostasis
Keywords: COX، Cyclo-Oxygenase; AA, arachidonic acid; AAPP, anopheline anti-platelet protein; ADP, adenosine diphosphate; aPTT, activated partial thromboplastin time; CI, confidence interval; COX, cyclo-oxygenase; DMSO, dimethyl sulfoxide; GP, glycoprotein; HCT, hematocrit; PATI, platel
Nuclear Factor-κB: Central Regulator in Ocular Surface Inflammation and Diseases
Keywords: COX، Cyclo-Oxygenase; angiogenesis; apoptosis; inflammation; NF-κB; signal transduction; transcription factors; wound healingAGE, Advanced glycation end products; CCL, Chemokine (C-C motif) ligand; COX, Cyclo-oxygenase; ds, Double-stranded; EGCG, Epigallocatechin gallate; ERK,
Non-steroidal anti-inflammatory drugs, tumour immunity and immunotherapy
Keywords: COX، Cyclo-Oxygenase; ADCC, antibody-dependent cellular cytotoxicity; Ad.E7, human papillomavirus (HPV) E7 protein; BCG, bacillus calmette-guerin; con A, concanavalin A; COX, cyclo-oxygenase; COXIBs, cyclo-oxygenase 2 (COX-2) inhibitors; CRT/E7, calreticulin linked to HPV16 E7
Purinergic mechanisms in gliovascular coupling
Keywords: COX، Cyclo-Oxygenase; AC, adenylyl cyclase; ASM, arteriolar smooth muscle; BBG, brilliant blue G; BKCa, large-conductance, Ca2+-operated K+ channel; CBF, cerebral blood flow; COX, cyclo-oxygenase; Cx43, connexin 43; EET, epoxyeicosatrienoic acid; e-NPP, ecto-pyrophosphatase/ph
Analgesic and nonsteroidal anti-inflammatory use in relation to nonmelanoma skin cancer: A population-based case-control study
Keywords: COX، Cyclo-Oxygenase; basal cell carcinoma; case-control study; nonmelanoma skin cancer; nonsteroidal anti-inflammatory drug; p53; PTCH; squamous cell carcinomaBCC, basal cell carcinoma; CI, confidence interval; COX, cyclo-oxygenase; HR, hazard ratio; LOH, loss of heterozygoci
Platelets at work in primary hemostasis
Keywords: COX، Cyclo-Oxygenase; CEACAM1, carcinoembryonic antigen cell adhesion molecule-1; COX, cyclo-oxygenase; DAG, 1,2-diacylglycerol; DTS, dense tubular system; GP, glycoprotein; ERK, extracellular signal-regulated kinase; Fg, fibrinogen; GPCR, G-protein coupled receptor; IP, prost
Inflammatory parameters in Caco-2 cells: Effect of stimuli nature, concentration, combination and cell differentiation
Keywords: COX، Cyclo-Oxygenase; COX, cyclo-oxygenase; IBDs, inflammatory bowel diseases; IECs, intestinal epithelial cells; iNOS, inducible nitric oxide synthase; LDH, lactate dehydrogenase; TEER, transepithelial electrical resistanceInflammation; Caco-2; IBD modeling; Cytokine; Lipopol
Therapeutic anti-inflammatory potential of formyl-peptide receptor agonists
Keywords: COX، Cyclo-Oxygenase; Formyl peptide; Endogenous anti-inflammation; Annexin A1; New chemical entities; Novel therapeutics; Neutrophil migrationAc2–26, Peptide Ac2–26 of Annexin A1; AnxA1, Annexin A1; βA42, Beta-amyloid 1–42; C43, Compound 43; COX, Cyclo-oxygenase; ATL, Aspirin
Sociodemographic Factors Influence Use of Proton Pump Inhibitors Among Users of Nonsteroidal Anti-Inflammatory Drugs
Keywords: COX، Cyclo-Oxygenase; CI, confidence interval; COX, cyclo-oxygenase; GI, gastrointestinal; GP, general practitioner; H2RAs, histamine-2 receptor antagonists; NSAIDs, nonsteroidal anti-inflammatory drugs; OR, odds ratio; PPI, proton pump inhibitor; PUB, perforation, peptic ulce
Descending control of nociception: Specificity, recruitment and plasticity
Keywords: COX، Cyclo-Oxygenase; COX, cyclo-oxygenase; C+ve, C-fiber input positive; C−ve, C-fiber input negative; DOR, δ opioid receptor; DRt, dorsal reticular nucleus of the caudal medulla; MOR, μ opioid receptor; PAG, periaqueductal gray; PGE2, prostaglandin E2; RVM, rostral ventromed
Lower Gastrointestinal Events in a Double-Blind Trial of the Cyclo-Oxygenase-2 Selective Inhibitor Etoricoxib and the Traditional Nonsteroidal Anti-Inflammatory Drug Diclofenac
Keywords: COX، Cyclo-Oxygenase; CI, confidence interval; COX, cyclo-oxygenase; CT, computed tomography; GI, gastrointestinal; HR, hazard ratio; RR, relative risk
Screening of senescence-associated genes with specific DNA array reveals the role of IGFBP-3 in premature senescence of human diploid fibroblasts
Keywords: COX، Cyclo-Oxygenase; BSA, bovine serum albumin; COX, cyclo-oxygenase; HDFs, human diploid fibroblasts; IGF-1, insulin-like growth factor-1; IGFBP-3, insulin-like growth factor binding protein-3; Rb, retinoblastoma protein; ROS, reactive oxygen species; S-A β-gal, senescence-a
Prostaglandin E receptor EP4 antagonist suppresses osteolysis due to bone metastasis of mouse malignant melanoma cells
Keywords: COX، Cyclo-Oxygenase; Prostaglandin E; EP4 receptor; Bone metastasis of cancer; Bone resorption; Malignant melanomaPGE, prostaglandin E; RANKL, receptor activator of NFκB ligand; TRAP, tartrate-resistant acid phosphatase; COX, cyclo-oxygenase; PTHrP, parathyroid hormone-relate
Efficacy of diclofenac in the prevention of post-ERCP pancreatitis in predominantly high-risk patients: a randomized double-blind prospective trial
Keywords: COX، Cyclo-Oxygenase; COX, cyclo-oxygenase; ES, endoscopic sphincterotomy; NSAID, nonsteroidal anti-inflammatory drug; SOD, sphincter of Oddi dysfunction
Leptin synergistically enhances the anti-apoptotic and growth-promoting effects of acid in OE33 oesophageal adenocarcinoma cells in culture
Keywords: COX، Cyclo-Oxygenase; BO, Barrett's oesophagus; COX, cyclo-oxygenase; DMEM, Dulbecco's modified eagle medium; DMSO, dimethyl sulfoxide; OAC, oesophageal adenocarcinoma; ELISA, enzyme-linked immunosorbent assay; EGFR, epidermal growth factor receptor; ERK, p42/44 extracellular
Curcumin, a Curcuma longa constituent, acts on MAPK p38 pathway modulating COX-2 and iNOS expression in chronic experimental colitis
Keywords: COX، Cyclo-Oxygenase; CD, Crohn's disease; COX, Cyclo-oxygenase; CUR, Curcumin; HETAB, Hexadecyl-trimethylammonium bromide; IBD, Inflammatory bowel disease; IFN, Interferon; IL, Interleukin; JNK, c-Jun N-terminal kinase; MAPKs, Mitogen-activated protein kinases; MPO, Myelopero
Evidence for adenosine- and serotonin-mediated antihyperalgesic effects of cizolirtine in rats suffering from diabetic neuropathy
Keywords: COX، Cyclo-Oxygenase; Diabetes; Neuropathic pain; Mechanical hyperalgesia; Cizolirtine; Serotonin; Adenosine5-HT, 5-Hydroxytryptamine, serotonin; ADO, adenosine; ANOVA, analysis of variance; CGRP, calcitonin gene-related peptide; COX, cyclo-oxygenase; CPA, cyclopentyladenosine
Chlorinative stress: An under appreciated mediator of neurodegeneration?
Keywords: COX، Cyclo-Oxygenase; Aβ, amyloid-β; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; Cdk, cyclin-dependent kinase; CNS, central nervous system; COX, cyclo-oxygenase; ECM, extracellular matrix; GM-CSF, granulocyte-macrophage colony-stimulating factor; GSH, glutathi
Structural pathology in a rodent model of osteoarthritis is associated with neuropathic pain: Increased expression of ATF-3 and pharmacological characterisation
Keywords: COX، Cyclo-Oxygenase; ANOVA, analysis of variance; ATF-3, activating transcription factor-3; COX, cyclo-oxygenase; DRG, dorsal root ganglia; gadd, growth arrest and DNA damage gene; IR, immunoreactivity; L (prefix), lumbar; MIA, mono-iodoacetate; MRI, magnetic resonance imagin
Probable role of spinal purinoceptors in the analgesic effect of Trigonella foenum (TFG) leaves extract
Keywords: COX، Cyclo-Oxygenase; ADP, adenosin-5′-diphosphate; COX, cyclo-oxygenase; 5,7-DHT, 5,7-dihydroxytryptamine; EIA, enzyme immunoassay; F.T., formalin test; i.p., intraperitoneal; i.t., intrathecal; LPS, lipopolysaccharide; NSAIDs, non-steroid anti-inflammatory drugs; PGE2, prost
Lack of chemopreventive effects of α-eleostearic acid on 7,12-dimethylbenz[a]anthracene (DMBA) and 1,2-dimethylhydrazine (DMH)-induced mammary and colon carcinogenesis in female Sprague–Dawley rats
Keywords: COX، Cyclo-Oxygenase; ACF, aberrant crypt foci; AOM, azoxymethane; CLA, conjugated linoleic acid; CLNA, conjugated α-linolenic acid; COX, cyclo-oxygenase; DHA, docosahexaenoic acid; DMBA, 7,12-dimethylbenz[a]anthracene; DMH, 1,2-dimethylhydrazine; EPA, eicosapentaenoic acid; H
Dietary lipids and intestinal inflammatory disease
Keywords: COX، Cyclo-Oxygenase; ALA, α Linolenic acid; ARA, Arachidonic acid; CD, Crohn’s disease; COX, Cyclo-oxygenase; DHA, Docosahexaenoic acid; EPA, Eicosapentaenoic acid; IBD, Inflammatory bowel disease; IL, Interleukin; LA, Linoleic acid; PC, Phosphatidylcholine; PE, Phosphatidyle
Glycine-extended gastrin stimulates proliferation and inhibits apoptosis in colon cancer cells via cyclo-oxygenase-independent pathways
Keywords: COX، Cyclo-Oxygenase; G-Gly, Glycine-extended gastrin; NSAIDs, nonsteroidal anti-inflammatory drugs; COX, cyclo-oxygenase; PGE-2, prostaglandin E2; ERK, p42/44 extracellular signal regulated kinase; p38 MAP kinase, p38 mitogen activated protein kinase; NF-κB, nuclear factor ka
Glycine-extended gastrin inhibits apoptosis in colon cancer cells via separate activation of Akt and JNK pathways
Keywords: COX، Cyclo-Oxygenase; AP-1, activator protein-1; COX, cyclo-oxygenase; DMEM, Dulbecco's modified eagle medium; DMSO, dimethyl sulfoxide; ELISA, enzyme-linked immunosorbent assay; FBS, foetal bovine serum; G-Gly, glycine-extended gastrin-17; JAK, Janus tyrosine kinase; JNK, c-J
Melanoma chemoprevention
Keywords: COX، Cyclo-Oxygenase; COX, cyclo-oxygenase; DFMO, difluoromethylornithine; EGCG, epigallocetechin 3-gallate; NSAID, nonsteroidal anti-inflammatory drug
Gastrin and cancer: A review
Keywords: COX، Cyclo-Oxygenase; Gastrin; Cancer; Colon; Pancreas; Stomach; Helicobacter pyloriACF, aberrant crypt foci; COX, cyclo-oxygenase; ECL, enterochromaffin-like; EGF, epidermal growth factor; ERK, extracellular-signal regulated kinase; FAK, focal adhesion kinase; HDC, histidine
Mediators of PGE2 synthesis and signalling downstream of COX-2 represent potential targets for the prevention/treatment of colorectal cancer
Keywords: COX، Cyclo-Oxygenase; COX, cyclo-oxygenase; NSAID, non steroidal anti-inflammatory drug; PG, prostaglandin; EP, E-prostanoid; Tx, thromboxane; FAP, familial adenomatous polyposis; HNPCC, hereditary non-polyposis colorectal cancerCOX-2; NSAID; Chemoprevention; Colon cancer; EP
Cytokines upregulate vascular endothelial growth factor secretion by human airway smooth muscle cells: Role of endogenous prostanoids
Keywords: COX، Cyclo-Oxygenase; VEGF, vascular endothelial growth factor; TGFβ, transforming growth factor beta; IL-1β, interleukin 1 beta; PGE2, prostaglandin E2; COX, cyclo-oxygenase; mRNA, messenger RNA; RT-PCR, reverse transcriptase polymerase chain reaction; HASM, human airway smoo