Effects of ceftriaxone on hydrocodone seeking behavior and glial glutamate transporters in P rats
Keywords: GLT-1; xCT; GLAST; Glutamate; Reinstatement; Hydrocodone; Opioids; CPP;
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Trypanothione reductase inhibition and anti-leishmanial activity of all-hydrocarbon stapled α-helical peptides with improved proteolytic stability
Keywords: Stapled peptides; Protein-protein interactions; Trypanothione reductase; Leishmania infantum; Cell-penetrating peptides; CD; circular dichroism; CPP; cell-penetrating peptide; ELISA; Enzyme-Linked ImmunoSorbent Assay; FCS; fetal calf serum; FITC; fluoresc
On the molecular structure, vibrational spectra, HOMO-LUMO, molecular electrostatic potential, UV-Vis, first order hyperpolarizability, and thermodynamic investigations of 3-(4-chlorophenyl)-1-(1yridine-3-yl) prop-2-en-1-one by quantum chemistry calculati
Keywords: NLO; CPP; HOMO-LUMO; Raman; FTIR; RMN;
Mechanism and Structural Factors of Lipid and Surfactant in the Formation of Self-Emulsified Nanoemulsion
Keywords: emulsion; surfactants; lipids; self-emulsifying; surface chemistry; free energy of interaction; colloid; micelle; thermodynamics; phase diagram; HLB; hydrophilic-lipophilic balance; HLD; hydrophilic lipophilic difference; Xmin; minimum mole fraction of a
Co-existing colloidal phases in artificial intestinal fluids assessed by AF4/MALLS and DLS: A systematic study into cholate & (lyso-) phospholipid blends, incorporating celecoxib as a model drug
Keywords: AF4; asymmetrical flow field-flow fractionation; CF; crossflow; CPP; critical packing parameter; CXB; celecoxib; DLS; dynamic light scattering; dRI; differential refractive index; FaSSIF; fasted state simulated fluid; FeSSIF; fed state simulated intestina
Negative chronotropism, positive inotropism and lusitropism of 3,5-di-t-butyl-4-hydroxyanisole (DTBHA) on rat heart preparations occur through reduction of RyR2 Ca2+ leak
Keywords: CPP; coronary perfusion pressure; ECG; electrocardiogram; LVP; left ventricle pressure; SR; sarcoplasmic reticulum; SERCA; sarcoplasmic-endoplasmic reticulum Ca2+ ATPase; Antioxidant phenol derivative; Isolated rat atria; Langendorff isolated rat heart; C
Brain disposition, metabolism and behavioral effects of the synthetic opioid AH-7921 in rats
Keywords: AH-7921; Analgesia; Metabolism; Pharmacokinetics; Rewarding effect; 2-Prop; iso-propylic alcohol; ACN; acetronitrile; ANOVA; analysis of variance; AUC; area under the curve; BBB; blood-brain-barrier; CID; collision-induced dissociation; Cmax; peak concent
Effects of rhynchophylline on the hippocampal miRNA expression profile in ketamine-addicted rats
Keywords: CPP; conditioned place preference; DOL; degree of labeling; IOD; integrated optical density; miRNA; microRNA; Rhy; Rhynchophylline; Nurr1; Nuclear receptor related 1 protein; Nr4a2; Nuclear receptor subfamily 4, group A, member 2; BDNF; Brain-derived neur
On the placement of controllers in software-Defined-WAN using meta-heuristic approach
Keywords: SDN; Controller; CPP; PSO; Backup path; Meta-Heuristic approach;
Metaplasticity at the addicted tetrapartite synapse: A common denominator of drug induced adaptations and potential treatment target for addiction
Keywords: Addiction; Nucleus accumbens; Glutamate; Tetrapartite synapse; Synaptic plasticity; Metaplasticity; LTD; Long term depression; LTP; Long term potentiation; NAc; Nucleus accumbens; CPP; Conditioned place preference; SA; Self-administration; PFC; Prefrontal
Stabilization of spherical nanoparticles of iron(III) hydroxides in aqueous solution by wormlike micelles
Keywords: Ksp; solubility product constant; WLM; wormlike micelles; CTAB; cetyltrimethylammonium bromide; NaSal; sodium salicylate; DLS; dynamic light scattering; SAXS; small angle X-ray scattering; TEM; transmission electron microscopy; Cryo-TEM; cryogenic transmi
Solution NMR views of dynamical ordering of biomacromolecules
Keywords: ALS; Amyotrophic Lateral Sclerosis; CPMG; Carr-Purcell-Meiboom-Gill; CPP; Cell Penetrating Peptide; CHO; Chinese Hamster Ovary Cells; Rex; Chemical/Conformational Exchange; (C)EST; (Chemical) Exchange Saturation Transfer; CSA; Chemical Shift Anisotropy; C
Hot-melt coating with Precirol ATO 5 in a fluidized-bed apparatus: Application of experimental design in the optimization of process parameters
Keywords: Granules; Paracetamol; Glycerol distearate; Size distribution; Flowability; Drug release; AAP; atomization air pressure; AUC; area under the drug release curve; BCS; Biopharmaceutics Classification System; CI; compressibility index; CPP; critical process
Substance P and neurotensin in the limbic system: Their roles in reinforcement and memory consolidation
Keywords: ACh; acetylcholine; BLA; basolateral amygdala; BNST; bed nucleus of stria terminalis; CeA; central nucleus of amygdala; CPU; caudate-putamen; CPP; conditioned place preference; DA; dopamine; dPAG; dorsal part of the periaqueductal gray matter; EPM; elevat
Regulatory-accepted drug development tools are needed to accelerate innovative CNS disease treatments
Keywords: ACR; American College of Radiology; AD; Alzheimer disease; ADNI; Alzheimer's Disease Neuroimaging Initiative; ALS; Amyotrophic Lateral Sclerosis; ASD; Autism Spectrum Disorder; BBB; Blood-Brain-Barrier; BEST; Biomarkers, Endpoints and other Tools; BLA; Bi
Protein tyrosine phosphatase conjugated with a novel transdermal delivery peptide, astrotactin 1-derived peptide recombinant protein tyrosine phosphatase (AP-rPTP), alleviates both atopic dermatitis-like and psoriasis-like dermatitis
Keywords: Atopic dermatitis; psoriasis; transdermal delivery peptide; protein tyrosine phosphatase; T-cell protein tyrosine phosphatase; transcutaneous drug; immunomodulatory protein; AD; Atopic dermatitis; AP; Astrotactin 1-derived peptide; CHS; Contact hypersen
Regulation of BAZ1A and nucleosome positioning in the nucleus accumbens in response to cocaine
Keywords: BDNF; brain-derived neurotrophic factors; ChIP; chromatin immunoprecipitation; CPP; conditioned place preference; NAc; nucleus accumbens; PMI; postmortem intervals; cocaine; addiction; epigenetics; chromatin; chromatin remodeling;
Long-term effects of maternal separation coupled with social isolation on reward seeking and changes in dopamine D1 receptor expression in the nucleus accumbens via DNA methylation in mice
Keywords: CpG; cytosine-phospho-guanine dinucleotide; CPP; conditioned place preference; DNMT; DNA methyltransferase; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; MS; maternal separation; MSÂ +Â SI; maternal separation coupled with social isolation; NAc; nucleu
Research articleTargeting neuronal nitric oxide synthase by a cell penetrating peptide Tat-LK15/siRNA bioconjugate
Keywords: NO; nitric oxide; nNOS; neuronal nitric oxide synthase; CPP; cell penetrating peptide; CNS; central neural system; RGC-5; Rat retinal ganglia cell; RNdsc; Rat Neurons-dorsal spinal cord; BBB; blood-brain barrier; FBS; Fetal Bovine Serum; Neuropathic pain;
Extra-hypothalamic brain clocks in songbirds: Photoperiodic state dependent clock gene oscillations in night-migratory blackheaded buntings, Emberiza melanocephala
Keywords: Bmal; brain and muscle arnt like protein; Cry; cryptochrome; Cb; cerebellum; CPI; piriform cortex; CPP; peripiriform cortex; EH; extra-hypothalamic; GLd; dorsal lateral geniculate nucleus; LDpM; long day premigratory; LDM; long day migratory; LDR; long da
D1-like dopamine receptor dysfunction in the lateral habenula nucleus increased anxiety-like behavior in rat
Keywords: ANOVA; analysis of variance; CPP; conditioned place preference; DA; dopamine; LHb; lateral habenula; VTA; ventral tegmental area; lateral habenula nucleus; dopamine; anxiety; depression; conditioned taste aversion;
Hydrogen sulfide attenuates calcification of vascular smooth muscle cells via KEAP1/NRF2/NQO1 activation
Keywords: Vascular smooth muscle cells; Calciprotein particles; Sulfide; H2S/HSâ; NQO1; VSMC; vascular smooth muscle cells; CKD; chronic kidney disease; CPP; calciprotein particles; H2S; hydrogen sulfide; NaHS; sodium hydrosulfide; NGS; next generation sequencing
Loi Jardé et règlement européen sur les essais de médicaments : harmonisation et mise en Åuvre des nouvelles réglementations
Keywords: Réglementation; Recherche clinique; Loi Jardé; Règlement européen; Effets indésirables; CPP; Phase 1; Formation;
Locomotor sensitization to intermittent ketamine administration is associated with nucleus accumbens plasticity in male and female rats
Keywords: Ketamine; Sex differences; Drug abuse; Nucleus accumbens; Sensitization; CPP; Spine density; ÎfosB; CaMKIIα; BDNF; GluA1;
Suppression of the acute upregulation of phosphorylated-extracellular regulated kinase in ventral tegmental area by a μ-opioid receptor agonist is related to resistance to rewarding effects in a mouse model of bone cancer
Keywords: Antinociception; Bone cancer pain; Extracellular regulated kinase; Opioid; Rewarding effect; GABA; γ-aminobutyric acid; CPP; conditioned place preference; FBC; femur bone cancer; NAC; nucleus accumbens; p-ERK; phosphorylated-extracellular regulated kinas
Oxytocin administration during spontaneous labor: Guidelines for clinical practice. Chapter 4: Oxytocin efficiency according to implementation in insufficient spontaneous labor
Keywords: ACOG; American College of Obstetricians and Gynecologists; CI; Confidence interval; CNGOF; French National College of Gynecologists and Obstetricians [Collège national des gynécologues et obstétriciens français]; CNSF; French National College of Midwi
Targeted release of transcription factors for human cell reprogramming by ZEBRA cell-penetrating peptide
Keywords: Valproic acid (PubChem CID: 3121); IPTG: Isopropyl-beta-d-thiogalactopyranoside (PubChem CID: 656894); DAPI: 4â²,6-diamidino-2-phénylindole (PubChem CID: 2 954); CPP; cell-penetrating peptides; FBS; fetal bovine serum; HSC; hematopoietic stem cells; HDA
Longitudinal Changes in LV Structure and Diastolic Function in Relation to Arterial Properties in General Population
Keywords: arterial stiffness; diastolic function; general population; left ventricular structure; AP; augmentation pressure; BP; blood pressure; cPP; central pulse pressure; EF; ejection fraction; HF; heart failure; LV; left ventricular; MAP; mean arterial pressure
Opioid-induced rewards, locomotion, and dopamine activation: A proposed model for control by mesopontine and rostromedial tegmental neurons
Keywords: μOR; mu opioid receptor; ACh; acetylcholine; AChR; acetylcholine receptor; ChAT; choline acetyltransferase; CPP; conditioned place preference; DA; dopamine; DREADD; designer receptors exclusively activated by designer drugs; GABA; gamma-aminobutyric acid
First example of peptides targeting the dimer interface of Leishmania infantum trypanothione reductase with potent in vitro antileishmanial activity#
Keywords: Peptides; Helix stabilization; Protein-protein interactions; Trypanothione reductase; Leishmania infantum; Cell-penetrating peptides; CPP; cell-penetrating peptide; DSSP; define secondary structure of proteins algorithm; ELISA; Enzyme-Linked ImmunoSorbent
Decreased anxiety, voluntary ethanol intake and ethanol-induced CPP acquisition following activation of the metabotropic glutamate receptor 8 “mGluR8”
Keywords: CPP; Conditioned Place Preference;; DCPG; (S)-3,4-dicarboxyphenylglycine; EPM; Elevated Plus Maze; EtOH; Ethanol; LDB; Light-Dark Box; MAP4; (S)-2-Amino-2-methyl-4-phosphonobutyric; mGluR; Metabotropic Glutamate Receptors; OF; Open Field; Anxiety; CPP; DC
Polysaccharides from Cyclocarya paliurus: Chemical composition and lipid-lowering effect on rats challenged with high-fat diet
Keywords: CPP; Cyclocarya paliurus polysaccharides; HFD; high fat diet; VAT; visceral adipose tissue; TC; total cholesterol; TG; triglycerides; LDL-C; low-density protein cholesterol; HDL-C; high-density protein cholesterol; GLU; glucose concentration; FAS; fatty a
Song-associated reward correlates with endocannabinoid-related gene expression in male European starlings (Sturnus vulgaris)
Keywords: 2-AG; 2-arachidonylglycerol; CPP; conditioned place preference; DAGLÉ; diacylglycerol lipase-É; FAAH; fatty acid amide hydrolase; FABP; fatty acid-binding protein; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; HMBS; hydroxymethylbilane synthase; PAG;
Long-term regulation of gene expression in muscle cells by systemically delivered siRNA
Keywords: 2â²-F; 2â²-fluoro; 2â²OMe; 2â²-O-methyl; Ago; argonaute; AME; absorptive-mediated endocytosis; AMT; absorptive-mediated transcytosis; BBB; blood-brain barrier; BMB; blood-muscle barrier; BMD; Becker muscular dystrophy; CPP; cell penetrating peptid
Role of perineuronal nets in the anterior dorsal lateral hypothalamic area in the acquisition of cocaine-induced conditioned place preference and self-administration
Keywords: Perineuronal nets; Extracellular matrix; Dorsal anterior lateral hypothalamic area; Conditioned place preference; Self-administration; Cocaine; Addiction; Drug-associated memory; Ch-ABC; chondroitinase-ABC; CPP; conditioned place preference; CSPGs; chondr
Full length articleControlled release of GAG-binding enhanced transduction (GET) peptides for sustained and highly efficient intracellular delivery
Keywords: Intracellular transduction; Controlled release; GAG-binding enhanced transduction (GET); CPP; PLGA; l-Histidine;
Clinical potential of oligonucleotide-based therapeutics in the respiratory system
Keywords: AGO; Argonaute; ASO; antisense oligonucleotide; CCR3; C-C chemokine receptor 3; CPP; cell penetrating peptide; COPD; chronic obstructive pulmonary disease; CD; cluster designation; GMCSF; granulocyte monocyte-colony stimulating factor; IL; interleukin;
Improving CPR Performance
Keywords: capnography; cardiac arrest; cardiopulmonary resuscitation without ventilation; contemporary reviews in critical care; CPR feedback device; AHA; American Heart Association; CPP; coronary perfusion pressure; ERC; European Resuscitation Council; ET-CO2; end
NFκB1 and NFκB2 gene expression in the prefrontal cortex and hippocampus of early life stressed mice exposed to cocaine-induced conditioned place preference during adolescence
Keywords: AFR; Animal Facility Reared; ANOVA; Analysis of Variance; BAFF; B-cell Activating Factor; BDNF; Brain-derived Neurotrophic Factor; CEUA; Ethics Committee on Animal Use; CPP; Conditioned Place Preference; MS; Maternal Separation; NAc; Nucleus Accumbens; NF
Novel CPR system that predicts return of spontaneous circulation from amplitude spectral area before electric shock in ventricular fibrillation
Keywords: AMSA; amplitude spectral area; AUC; area under the curve; AED; automated external defibrillators; CPP; coronary perfusion pressure; ECG; electrocardiogram; EMS; emergency medical service; ROC; receiver operating curves; ROSC; return of spontaneous circula
Increased cellular uptake of peptide-modified PEGylated gold nanoparticles
Keywords: Gold nanoparticles; Cell uptake; CPP; SPR; TEM;
Carbachol-induced network oscillations in an in vitro limbic system brain slice
Keywords: ACSF; artificial cerebrospinal fluid; CA3; CA3 region of the hippocampus; CCh; carbachol; CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; CPP; 3-(2-carboxypiperazin-4-yl)-propyl-1-phosphonate; EC; entorhinal cortex; GABAA; γ-aminobutyric acid type A receptor
CyLoP-1: Membrane-active peptide with cell-penetrating and antimicrobial properties
Keywords: AMP; Antimicrobial peptide; CFU; Colony forming units; CPP; Cell-penetrating peptide; CLSM; Confocal laser scanning microscopy; CPW; Cell protoplast washing solution; CyLoP-1; Cytosol localizing peptide-1; DMEM; Dulbecco's modified Eagle's medium; DMSO; D
Improved proteolytic stability and potent activity against Leishmania infantum trypanothione reductase of α/β-peptide foldamers conjugated to cell-penetrating peptides
Keywords: α/β-Peptides; Foldamers; Proteolysis; Protein-protein interactions; Trypanothione reductase; Leishmania infantum; CPP; cell-penetrating peptide; DSSP; define secondary structure of proteins algorithm; ELISA; Enzyme-Linked ImmunoSorbent Assay; 5-FITC; fl
Biological and pathophysiological roles of end-products of DHA oxidation
Keywords: PUFA; polyunsaturated fatty acids; CEP; 2-(Ï-Carboxyethyl)pyrrole; CPP; 2-(Ï-carboxypropyl)pyrrole; CHP; 2-(Ï-carboxyheptyl)pyrrole; DHA; docosahexaenoic acid; TLR; toll-like receptor; AMD; age-related macular degeneration; ROS; reactive oxygen species
STM probing the supramolecular coordination chemistry on solid surface: Structure, dynamic, and reactivity
Keywords: 1D; one-dimensional; 2D; two-dimensional; 3D; three-dimensional; BDBA; 4,4â²-di-(1,4-buta-1,3-diynyl)benzoic acid; BP; 4,4â²-bipyridine; t-Bu2Ph; 3,5-di-tert-butylphenyl; cis-BTP-TPE; cis-bis-terpyridine tetraphenyl ethylene; (C12OPc)2Er; bis[octakis(do
Neural mechanisms of the nucleus accumbens circuit in reward and aversive learning
Keywords: NAc; nucleus accumbens; GPi; globus pallidus interna; GPe; globus pallidus externa; VP; ventral pallidum; STN; subthalamic nucleus; SNr; substantia nigra pars reticulate; SNc; substantia nigra pars compacta; VTA; ventral tegmental area; MSN; medium spiny
Using the relationship between brain tissue regional saturation of oxygen and mean arterial pressure to determine the optimal mean arterial pressure in patients following cardiac arrest: A pilot proof-of-concept study
Keywords: AHA; American Heart Association; CCU; coronary care unit; COx; correlational coefficient between MAP and rSO2; CPP; cerebral perfusion pressure; FVd/FVm; flow velocity diastolic/mean; HIBI; hypoxemic ischemic brain injury; ICP; intracranial pressure; ICU;
Role of the NMDA receptor GluN2D subunit in the expression of ketamine-induced behavioral sensitization and region-specific activation of neuronal nitric oxide synthase
Keywords: CPP; 3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid; GluN2D-KO; GluN2D knockout; NADPH-d; nicotinamide adenine dinucleotide hydrogen phosphate diaphorase; NBT; nitroblue tetrazolium; NMDAR; NMDA receptor; nNOS; neuronal nitric oxide synthase; NO; nit
Electrochemical corrosion of Zircaloy-2 under PWR water chemistry but at room temperature
Keywords: Zircaloy-2; LiOH; H3BO3; CPP; SEM;