The effect of competitive antagonist chain length on NMDA receptor subunit selectivity
Keywords: NMDA; Glutamate; Xenopus oocytes; NR2; Antagonist; CPP;
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Hyperacute measurement of brain-tissue oxygen, carbon dioxide, pH, and intracranial pressure before, during, and after cerebral angiography in patients with aneurysmatic subarachnoid hemorrhage in poor condition
Keywords: CPP; cerebral perfusion pressure; CT; computed tomography; ICP; intracranial pressure; Ptico2; brain-tissue carbon dioxide pressure; Ptio2; brain-tissue oxygen pressure; SAH; subarachnoid hemorrhage; Subarachnoid hemorrhage; Brain tissue oxygenation; Angi
Levosimendan improves postresuscitation outcomes in a rat model of CPR
Keywords: CI; cardiac index; CPR; cardiopulmonary resuscitation; CPP; coronary perfusion pressure; dP/dt40; rate of left-ventricular pressure increase; âdP/dt; rate of maximal left-ventricular pressure decline; LIDO; levosimendan infusion versus dobutamine; MAP;
The role of mPer1 in morphine dependence in mice
Keywords: drug dependence; DNAzyme; learning and memory; circadian; i.c.v; CPP; conditioned place preference; ODN; oligonucleotide; Per; Period; ZT; zeitgeber time;
Psychostimulants and monoamine transporters: upsetting the balance
Keywords: ADHD; attention deficit hyperactivity disorder; AMPH; amphetamine; CPP; conditioned place preference; DAT; dopamine transporter; KO; knockout; METH; methamphetamine; MDMA; 3,4-methylenedioxymethamphetamine; NET; norepinephrine transporter; PKC; protein ki
Internalisation of cell-penetrating peptides into tobacco protoplasts
Keywords: CPP; cell-penetrating peptide; cv; cultivar; EDTA; ethylenediaminetetraacetate; FACS; fluorescence-activated cell sorter; FITC; fluorescein isothiocyanate; Fl; fluoresceinyl; HEPES; N-(2-Hydroxyethyl)piperazine-Nâ²-(2-ethanesulfonic acid); HKR; HEPES-buf
Local injection of a glutamate uptake inhibitor into the ventral tegmental area produces sensitization to the behavioural effects of d-amphetamine
Keywords: behavioral sensitization; psychostimulant; excitatory amino acid; ANOVA; analysis of variance; CPP; (±)-3-(2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid; DA; dopaminergic; EAA; excitatory amino acid; FR; front-rear; l-trans-PDC; l-trans-pyrollidine-2
Progesterone inhibits behavioral responses and estrogen increases corticosterone levels after acute cocaine administration
Keywords: CNS; central nervous system; s.c.; subcutaneous; i.p.; intraperitoneal; CPP; conditioned place preference; HPA; hypothalamic-pituitary-adrenal; Estrogen; Progesterone; Gonadal hormones; Females;
Morphine preexposure facilitates morphine place preference and attenuates morphine taste aversion
Keywords: Morphine; Drug preexposure; Reward; Aversion; CTA; CPP;
Cellular mechanisms underlying an effect of “early handling” on pCREB and BDNF in the neonatal rat hippocampus
Keywords: Neural basis of behavior; Neural plasticity; 5-HT; serotonin; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ANOVA; analysis of variance; BDNF; brain-derived neurotrophic factor; CA1 area; field 1 of Ammon's horn; CNQX; 6-cyano-7-nitroquinox
Sympathoexcitatory effects of estrogen in the insular cortex are mediated by GABA
Keywords: Endocrine and autonomic regulation; Cardiovascular regulation; Saclofen; DNQX; CPP; Autonomic tone; Cardiac baroreceptor reflex;
Present and future of cell-penetrating peptide mediated delivery systems: “Is the Trojan horse too wild to go only to Troy?”
Keywords: CPP; cell penetrating peptide; GST; gluthation S-transferase; GFP; green fluorescent protein; FACS; fluorescence-activated cell sorter; PMO; morpholino oligomers; HPMA; N-(2-hydroxypropyl)methacrylamide; Cell delivery; Cell-penetrating peptide (CPP); Targ
Corticotrophin-releasing hormone decreases synaptic transmission in rat sensorimotor cortex in vivo
Keywords: neocortex; plasticity; hormones; LTP; LTD; stress; CPP; â3-(2-carboxypiperazin-4-yl)-propyl-1-phosphonate; CRH; corticotrophin-releasing hormone; NMDA; N-methyl-d-aspartate;
Increased gabaergic input to ventral tegmental area dopaminergic neurons associated with decreased cocaine reinforcement in μ-opioid receptor knockout mice
Keywords: opioids; addiction; ventral tegmental area; GABA; dopamine; cocaine; aCSF; artificial cerebrospinal fluid; CPP; conditioned place preference; DAMGO; [d-Ala, Nme-Phe, Gly-ol]-enkephalin; mIPSC; miniature inhibitory post-synaptic current; MOR; μ-opioid rec
Evidence that membrane transduction of oligoarginine does not require vesicle formation
Keywords: α-MEM; α-minimum essential medium; AEBSF; 4-(2-aminoethyl)-benzenesulfonyl fluoride hydrochloride; CHO; Chinese hamster ovary; CPP; cell-penetrating peptide; E-64; (2S,3S)-3-(N-{(S)-1-[N-(4-guanidinobutyl)carbamoyl]3-methylbutyl}carbamoyl)-oxirane-2-car
Resuscitation with Pressors after Traumatic Brain Injury
Keywords: AVP; arginine vasopressin; CPP; cerebral perfusion pressure; ICP; intracranial pressure; MAP; mean arterial pressure; NS; normal saline; PbtO2; brain tissue partial oxygen pressure; PE; phenylephrine; SvO2; mixed venous oxygen saturation; TBI; traumatic b
Membrane destabilizing properties of cell-penetrating peptides
Keywords: CF; 5- (and 6-) carboxyfluorescein; CHO; Chinese hamster ovary; CPP; cell-penetrating peptide; DPPG; 1,2-dipalmitoyl-sn-glycero-3-phosphoglycerol; DOPC; 1,2-dioleoyl-sn-glycero-3-phosphocoline; DOPG; 1,2-dioleoyl-sn-glycero-3-phosphoglycerol; DSPE-PEG; 1,
Membrane perturbation effects of peptides derived from the N-termini of unprocessed prion proteins
Keywords: PrP; prion protein; PrPC; cellular isoform of PrP; PrPSc; scrapie isoform of PrP; mPrPp; peptide with sequence corresponding to the N-terminus of the mouse prion protein, residues 1-28; bPrPp; peptide with sequence corresponding to the N-terminus of the
Role of NMDA receptors in the syndrome of behavioral changes produced by predator stress
Keywords: Acoustic startle; Anxiety; Asymmetry; CPP; Elevated plus maze; Habituation; Light/dark box; LTP; NMDA receptors; Predator stress; Rat; Risk assessment; Social interaction;
Effects of cargo molecules on the cellular uptake of arginine-rich cell-penetrating peptides
Keywords: CPP; cell penetrating peptide; DIEA; diisopropylethylamine; DMEM; Dubelcco's Modified Eagle Medium; DMF; dimethylformamide; DMPC; dimyristoyl phosphatidylcholine; DMPG; dimyristoyl phosphidylglycerol; DMSO; dimethylsulfoxide; FBS; fetal bovine serum; Fl
ATP-loaded liposomes effectively protect mechanical functions of the myocardium from global ischemia in an isolated rat heart model
Keywords: ATP; adenosine-5â²-triphosphate; ATPase; adenosine-5â²-triphosphatase; ATP-L; liposomes loaded with ATP; F-ATP; free ATP in Krebs-Henseleit buffer; EL; empty liposomes; CPP; coronary perfusion pressure; LV; left ventricle; LVDP; left ventricular devel
Periodic oscillatory activity in parahippocampal slices maintained in vitro
Keywords: parahippocampal networks; oscillatories; GABA; glutamatergic transmissions; gap junction; ACSF; artificial cerebrospinal fluid; baclofen; 4-amino-3-[4-chlorophenyl]-butanoic acid; BLA; basolateral/lateral nuclei of the amygdala; CCh; carbachol; CGP 55845;
Estrogen synthesis in the central nucleus of the amygdala following middle cerebral artery occlusion: Role in modulating neurotransmission
Keywords: stroke; letrozole; autonomic tone; estrogen synthesis; NMDA and non-NMDA receptors; aCSF; artificial cerebrospinal fluid; ANOVA; analysis of variance; BRS; baroreceptor reflex sensitivity; CNA; central nucleus of the amygdala; CPP; (±)-3-(2-carboxypipera
Evaluation of cell penetrating peptides fused to elastin-like polypeptide for drug delivery
Keywords: Antp; penetratin peptide from Antennapaedia; CPP; cell penetrating peptide; ELP; elastin-like polypeptide; MβCD; methyl-β-cyclodextrin; MTS; membrane translocating sequence from Kaposi fibroblast growth factor; PBS; phosphate buffered saline; PNA; pepti
N-methyl-d-aspartate receptors and large conductance calcium-sensitive potassium channels inhibit the release of opioid peptides that induce μ-opioid receptor internalization in the rat spinal cord
Keywords: dorsal horn; dynorphin; enkephalin; internalization; mu-opioid receptor; opioid; aCSF; artificial cerebrospinal fluid; ANOVA; analysis of variance; AP-5; dl-2-amino-5-phosphonopentanoic acid; BK(Ca2+); large conductance Ca2+-sensitive K+ channels; CCK; ch
Emerging Medical and Surgical Management Strategies in the Evaluation and Treatment of Intracerebral Hemorrhage
Keywords: CBF; cerebral blood flow; CPP; cerebral perfusion pressure; CSF; cerebrospinal fluid; CT; computed tomography; FFP; fresh frozen plasma; GCS; Glasgow Coma Scale; ICH; intracerebral hemorrhage; ICP; intracranial pressure; IV; intravenous; IVH; intraventric
GABAA receptor facilitation of neurokinin release from primary afferent terminals in the rat spinal cord
Keywords: C-fiber; dorsal horn; GABA; internalization; neurokinin 1 receptor; substance P; aCSF; artificial cerebrospinal fluid; ANOVA; analysis of variance; CGP-55845; (2S)-3-[[(1S)-1-(3,4-dichlorophenyl)ethyl]amino-2-hydroxypropyl](phenylmethyl) phosphinic acid;
Bilayer interaction and localization of cell penetrating peptides with model membranes: A comparative study of a human calcitonin (hCT)-derived peptide with pVEC and pAntp(43-58)
Keywords: CPP; cell penetrating peptide; hCT; human calcitonin; pVEC; vascular endothelial cadherin-derived CPP; pAntp; penetratin, Antennapedia homeodomain-derived CPP; POPC; 1-palmitoyl-2-oleoyl-phosphatidylcholine; POPG; 1-palmitoyl-2-oleoyl-phosphatidylglycerol
Some recent results on the distributions of stopping times of compound Poisson processes with linear boundaries
Keywords: 60G17; 60G40; Compound Poisson processes; Stopping times; Linear boundaries; CPP; Compound Poisson processes; C.d.f.; Cumulative distribution function; I.i.d.; Independent identically distributed; G/M; General compound renewal process with exponential jum
Hyperventilation in Head Injury
Keywords: cerebral ischemia; hyperventilation; intracranial pressure; traumatic brain injury; AVDO2; cerebral arteriovenous difference of oxygen content; CBF; cerebral blood flow; CMRO2; cerebral metabolic rate of oxygen; CPP; cerebral perfusion pressure; CSF; cere
Role of NMDA receptors in the lateralized potentiation of amygdala afferent and efferent neural transmission produced by predator stress
Keywords: Anxiety; Asymmetry; Central amygdala; CPP; Elevated plus maze; Evoked potential; Habituation; Hemispheres; Light/dark box; LTP; NMDA receptors; Periaqueductal gray; PAG; Predator stress; Rat; Risk assessment; Social interaction; Startle;
Endocannabinoid system and opioid addiction: Behavioural aspects
Keywords: AC; Adenylyl cyclase (AC); ACTH; Adrenocorticotrophic hormone; cAMP; Adenosine 3â²-5â²-cyclic monophosphate; CB1; Central cannabinoid (receptor); CP; Caudate-putamen; CP 55,940; (â)-cis-3-[2-hydroxy-4(1,1-dimethyl-heptyl)-phenyl]-trans-4-(3-hydroxy-
Experimental models of traumatic brain injury: Do we really need to build a better mousetrap?
Keywords: review; diffuse injury; focal injury; head injury; literature review; BBB; blood-brain barrier; CBF; cerebral blood flow; CCI; closed cortical impact; CDC; Centers for Disease Control and Prevention; CPP; cerebral perfusion pressure; DAI; diffuse axonal
Tat peptide-mediated cellular delivery: back to basics
Keywords: TAT; Uptake; Cell delivery; CPP;
Role of cell signaling in B[a]P-induced apoptosis: characterization of unspecific effects of cell signaling inhibitors and apoptotic effects of B[a]P metabolites
Keywords: α-NF; α-naphthoflavone; AHR; aryl hydrocarbon receptor; B[a]P; benzo[a]pyrene; B[a]P-4,5-DHD; (±)-benzo[a]pyrene-trans-4,5-dihydrodiol; B[a]P-7,8-DHD; (±)-benzo[a]pyrene-trans-7,8-dihydrodiol; B[a]P-9,10-DHD; (±)-benzo[a]pyrene-trans-9,10-dihydrodiol
Free radicals as triggers of brain edema formation after stroke
Keywords: ADC; apparent diffusion coefficient; AJ; adherens junction; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AQP; aquaporin; ATP; adenosine triphosphate; BBB; blood-brain barrier; CBF; cerebral blood flow; cGMP; cyclic guanosine monophosphat
N-methyl-d-aspartate (NMDA) and the regulation of mitogen-activated protein kinase (MAPK) signaling pathways: A revolving neurochemical axis for therapeutic intervention?
Keywords: AA; arachidonic acid; AIDS; acquired immunodeficiency syndrome; ALS; amyotrophic lateral sclerosis; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; APV; 2-amino-5-phosphonovalerate; 2-AP5; 2-amino-5-phosphonopentanoic acid; ATF; activating tr