Voluntary oral nicotine intake in mice down-regulates GluR2 but does not modulate depression-like behaviors
Keywords: Nicotine; 2-Bottle choice; Behavior; AMPA receptors; CREB
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Microwave irradiation induces neurite outgrowth in PC12m3 cells via the p38 mitogen-activated protein kinase pathway
Keywords: Microwave; Neurite outgrowth; p38 MAP kinase; CREB; PC12 mutant cells;
Use of calcium imaging for analysis of neuronal gap junction coupling
Keywords: Connexin; Gap junctions; Calcium imaging; NMDA receptors; CREB; Cultures
Caffeine improves adult mice performance in the object recognition task and increases BDNF and TrkB independent on phospho-CREB immunocontent in the hippocampus
Keywords: Caffeine; Neurotrophins; Growth factors; CREB; Psychostimulants; Discrimination memory; Recognition memory
COX-2 promoter activation by AT1R-Gq-PAK-p38β signaling in intestinal epithelial cells
Keywords: Cyclooxygenase-2; Angiotensin II; CREB; PAK; IEC-18 cell
PTH regulation of the human cytomegalovirus immediate-early gene promoter
Keywords: Parathyroid hormone; Human cytomegalovirus; Immediate-early gene; Transcription; CREB; ATF-1; DNA; Kidney; Chronic allograft nephropathy; Tubular cells
Activation of amygdaloid PKC pathway is necessary for conditioned cues-provoked cocaine memory performance
Keywords: Amygdala; Cocaine; PKC; CREB; Pavlovian conditioning; Protein synthesis
Acute Hippocampal Brain-Derived Neurotrophic Factor Restores Motivational and Forced Swim Performance After Corticosterone
Keywords: Anhedonia; BDNF; CREB; glucocorticoid; hippocampus; motivation; progressive ratio; stress
The molecules of social recognition memory: Implications for social cognition, extended mind, and neuroethics
Keywords: Social cognition; Memory consolidation; CREB; Extended mind; Neuroethics
Loss of responsiveness to melatonin in the aging mouse suprachiasmatic nucleus
Keywords: Mel1a; MT1; Melatonin receptor; Circadian; Chronobiology; CREB; PACAP; Biological rhythms
Regulating gene transcription in response to cyclic AMP elevation
Keywords: cAMP; Gene transcription; CREB; PKA; Epac
Hypercholesterolemia-induced Aβ accumulation in rabbit brain is associated with alteration in IGF-1 signaling
Keywords: Akt; Alzheimer's disease; β-amyloid; Cholesterol; CREB; GSK-3α; Hippocampus; Insulin degrading enzyme; 27-hydroxycholesterol
Coactivator PGC-1α regulates the fasting inducible xenobiotic-metabolizing enzyme CYP2A5 in mouse primary hepatocytes
Keywords: CYP; cytochrome P450; PGC-1α; peroxisome proliferator-activated receptor γ coactivator 1α; cAMP; cyclic adenosine monophosphate; HNF-4α; hepatocyte nuclear factor 4α; PPAR; peroxisome proliferator-activated receptor; COH; coumarin 7-hydroxylase; Q-PC
Regulation of cyclooxygenase-2 expression by cAMP response element and mRNA stability in a human airway epithelial cell line exposed to zinc
Keywords: COX; cyclooxygenase; LPS; lipopolysaccharide; CRE; cyclic AMP response element; AP-1; activator protein 1; C/EBP; CCAAT/enhancer binding protein; NF-IL-6; nuclear factor interleukin-6; ATF; activating transcription factor; CREB; CRE-binding protein; USF-1
Regulation of aquaporin 3 expression by magnesium ion
Keywords: Aquaporin 3; Magnesium ion; CREB; Adenylyl cyclase; Antacid; Water channel
Adenosine A2A receptor dynamics studied with the novel fluorescent agonist Alexa488-APEC
Keywords: G protein-coupled receptor; Endocytosis; Cyclic AMP; CREB; Nucleoside; Rab5; Clathrin
Diminished expression of ACTH signaling proteins and steroidogenic limiting factors in adrenocortical cells isolated from halothanenn pigs
Keywords: Pigs; Adrenocortical cells; Halothane; Cortisol; StAR; P450scc; CREB;
NMDA-induced neuroprotection in hippocampal neurons is mediated through the protein kinase A and CREB (cAMP-response element-binding protein) pathway
Keywords: Glutamate; Excitotoxicity; N-Methyl-d-aspartate; CREB; Neuroprotection
Fluoxetine increases the activity of the ERK-CREB signal system and alleviates the depressive-like behavior in rats exposed to chronic forced swim stress
Keywords: ERK; CREB; Stress; Antidepressant; Hippocampus; Prefrontal cortex
Overexpression of post-translationally modified peptides in Escherichia coli by co-expression with modifying enzymes
Keywords: Phosphorylation; Hydroxylation; Co-expression; Escherichia coli; B1 domain of protein G (GB1); CREB; HIF-1α;
Endothelin-1 induces glut1 transcription through enhanced interaction between Sp1 and NF-κB transcription factors
Keywords: Endothelin-1; Glut1; Transcription; Sp1; NF-κB; CREB
A p38 MAPK–CREB pathway functions to pattern mesoderm in Xenopus
Keywords: VMZ, Ventral Marginal Zone; DMZ, Dorsal Marginal Zone; DLMZ, Dorsal Lateral Marginal Zone; AC, Animal Cap; AMO, Antisense Morpholino Oligonucleotide; MAPK, Mitogen-Activated Protein KinaseSpemann's organizer; CREB; p38 MAPK; Mesoderm patterning; Xenopus l
Bacopa monniera ameliorates amnesic effects of diazepam qualifying behavioral-molecular partitioning
Keywords: amnesia; benzodiazepine; behavioral-molecular; Bacopa monniera; diazepam; water maze; cAMP; cyclic adenosine monophosphate; CREB; cAMP response element binding protein; ELT; escape latency time; ERK; extracellular signal-regulated kinase; iNOS; inducible
Exendin-4 and exercise promotes β-cell function and mass through IRS2 induction in islets of diabetic rats
Keywords: Insulin secretion; β-cell growth; Insulinotropic action; GLP-1; IRS2; CREB
Transfection of mutant CREB in the striatum, but not the hippocampus, impairs long-term memory for response learning
Keywords: Dorsolateral striatum; CREB; Hippocampus; Consolidation; Interaction; Cross maze; Herpes simplex virus; Multiple memory systems
BDNF-exercise interactions in the recovery of symmetrical stepping after a cervical hemisection in rats
Keywords: spinal cord injury; locomotion; TrkB IgG; synaptic plasticity; neurotrophin; BDNF; brain-derived neurotrophic factor; Con; sedentary control group; CREB; cyclic AMP response element binding protein; Ex; exercised hemisected group; GAPDH; glyceraldehyde-3-
Coping with the stress: Expression of ATF4, ATF6, and downstream targets in organs of hibernating ground squirrels
Keywords: Activating transcription factor; Unfolded protein response; Endoplasmic reticulum stress; PERK; CREB; Spermophilus tridecemlineatus; Torpor
CREB-dependent gene regulation by prion protein: Impact on MMP-9 and β-dystroglycan
Keywords: Prion; Signaling; CREB; IEG; Metalloproteases; Neuron
Impaired spatial learning related with decreased expression of calcium/calmodulin-dependent protein kinase IIα and cAMP-response element binding protein in the pentylenetetrazol-kindled rats
Keywords: Epilepsy; Spatial learning and memory; [Ca2+]i; CaMKIIα; CREB; Nimodipine
Pharmacological application of caffeine inhibits TGF-β-stimulated connective tissue growth factor expression in hepatocytes via PPARγ and SMAD2/3-dependent pathways
Keywords: 15-PGJ2; 15 deoxy prostaglandin J2; 8-Br-cAMP; 8-bromoadenosine-3â²,5â²-cyclic adenosine monophosphate; Alk4/Alk5; activin like receptor 4/5; cAMP; cyclic adenosine monophosphate; cAMP-PDE; cAMP-specific phosphodiesterase; CBP; CREB binding protein; co;
CREB Binding and Activity in Brain: Regional Specificity and Induction by Electroconvulsive Seizure
Keywords: cAMP; chromatin immunoprecipitation; CREB; electroconvulsive seizure; microarray; transcription
Dopamine D1 receptor-mediated aggregation of N-terminal fragments of mutant huntingtin and cell death in a neuroblastoma cell line
Keywords: Huntington's disease; G-protein-coupled receptors; cell survival; dopamine receptors; cAMP; 3â²-5â²-cyclic AMP; CREB; 3â²-5â²-cyclic AMP response element-binding; DMEM; Dulbecco's modified eagle's medium; EGFP; enhanced green fluorescent protein; GAPD
Research ReportThe activation of extracellular signal-regulated protein kinase 5 in spinal cord and dorsal root ganglia contributes to inflammatory pain
Keywords: MAPKs; mitogen-activated protein kinases; ERK5; extracellular signal-regulated protein kinase 5; DRG; dorsal root ganglion; CFA; complete Freund's adjuvant; CREB; cAMP response-element binding protein; ERK1/2; extracellular signal-regulated kinase 1/2; JN
Effects of chronic network hyperexcitability on the growth of hippocampal dendrites
Keywords: CREB; Epilepsy; NMDA; Seizure; Slice culture;
Difference in sensory dependence of occ1/Follistatin-related protein expression between macaques and mice
Keywords: Brain evolution; In situ hybridization; TSC-36/FSTL1; V1-specific; CREB
Additive effects of histone deacetylase inhibitors and amphetamine on histone H4 acetylation, cAMP responsive element binding protein phosphorylation and ÎFosB expression in the striatum and locomotor sensitization in mice
Keywords: histone deacetylase; cAMP responsive element binding protein; chromatin immunoprecipitation; butyric acid; valproic acid; amphetamine; AcH4; acetylated H4; BA; butyric acid; B+S; butyric acid+saline; ChIP; chromatin immunoprecipitation; co-IP; co-immunopr
Axotomy or compression is required for axonal sprouting following end-to-side neurorrhaphy
Keywords: End-to-side neurorrhaphy; Myelin associated glycoprotein; Epineurotomy; CREB; Transgenic; Regeneration
Regulation of transcription factors by nitric oxide in neurons and in neural-derived tumor cells
Keywords: Nitric oxide; CREB; N-Myc; Neuron survival; Neurogenesis; Proliferation; Neural-derived tumor cells;
In cardiac myocytes, cAMP elevation triggers the down-regulation of transcripts and promoter activity for cyclic AMP phosphodiesterase-4A10 (PDE4A10)
Keywords: cAMP phosphodiesterase; PDE4; Rolipram; ICER; Promoter; Sp1; CRE; CREB; PKA; Cardiac myocytes; Beta-adrenoceptor; Isoprenaline; Compartmentation; Compartmentalisation
Regulation of cardiac excitation and contraction by p21 activated kinase-1
Keywords: Protein phosphatase 2A; L-type Ca2+-channel; Sarcomeric protein phosphorylation; Ryanodine receptor; AC; denylate cyclase; Ad; adenovirus; BK channel; Ca2+-activated K+ currents; B(PR55); PP2A regulatory subunits; Bâ²(PR61); PP2A regulatory subunits; Bâ
Gastrin transactivates the chromogranin A gene through MEK-1/ERK- and PKC-dependent phosphorylation of Sp1 and CREB
Keywords: CgA; chromogranin A; ECL cells; enterochromaffin-like cells; HDC; histidine decarboxylase; ERK; extracellular-signal regulated kinase; PKC; protein kinase C; CRE; cAMP responsive element; cAMP; cyclic adenosine mono phosphate; CREB; CRE binding protein.;
Retinoic acid induces caspase-8 transcription via phospho-CREB and increases apoptotic responses to death stimuli in neuroblastoma cells
Keywords: Caspase-8; Neuroblastoma; Medulloblastoma; Small cell lung carcinoma; Retinoid; Retinoic acid; CREB; Apoptosis; Transcription;
Beneficial effects of rolipram in the R6/2 mouse model of Huntington's disease
Keywords: Phosphodiesterase inhibitors; CREB; Huntington's disease; Transgenic mouse; Confocal microscopy
Regulation of cyclic AMP response-element binding-protein (CREB) by Gq/11-protein-coupled receptors in human SH-SY5Y neuroblastoma cells
Keywords: CREB; cyclic AMP response-element binding-protein; ERK; extracellular signal-regulated kinase; GPCR; G-protein-coupled receptor; IBMX; 3-isobutyl-1-methylxanthine; mACh; muscarinic acetylcholine; MAPK; mitogen-activated protein kinase; PDBu; phorbol 12,13
Alteration of CREB phosphorylation and spatial memory deficits in aged 129T2/Sv mice
Keywords: Aging; Memory; CREB; Fos; Hippocampus; Immunohistochemistry; Water maze
Membrane phospholipids, lipoxidative damage and molecular integrity: A causal role in aging and longevity
Keywords: AA; arachidonic acid; AKR; aldo-keto reductase; ALDH; aldehyde dehydrogenase; ALEs; advanced lipoxidation end-product; ARE; antioxidant response element; CBP; CREB-binding protein; CR; caloric restriction; CREB; cAMP-responsive element-binding factor; DBI
Inhibition of GSK3 differentially modulates NF-κB, CREB, AP-1 and β-catenin signaling in hepatocytes, but fails to promote TNF-α-induced apoptosis
Keywords: TNF-α; Wnt; NF-κB; AP-1; CREB; β-catenin; Glycogen synthase kinase-3; Hepatocyte; Liver; Apoptosis;
Intranasal delivery of insulin and a nitric oxide synthase inhibitor in an experimental model of amyotrophic lateral sclerosis
Keywords: amyotrophic lateral sclerosis; insulin; free oxygen radicals; endplate innervation; behavior testing; electrophysiology; ALS; amyotrophic lateral sclerosis; ChAT; choline acetyltransferase; CMAP; compound motor action potential; CREB; cAMP response elemen
The role of protein synthesis in memory consolidation: Progress amid decades of debate
Keywords: Protein synthesis; RNA synthesis; Consolidation; Memory; Amnesia; Reconsolidation; Protein synthesis inhibitor; Sleep; Gene expression; Transcription; Translation; Knockout; Synaptic; Systems; Side effects; Rescue; Hippocampus; Learning; LTP; cAMP; CREB;
Phosphodiesterase 10A inhibition is associated with locomotor and cognitive deficits and increased anxiety in mice
Keywords: Papaverine hydrochloride; Stress; Morris water maze; Light–Dark Test; Learning and memory; Huntington’s disease; Motor skills; CREB; PDE10A; Western blot