Deficits in ERK and CREB activation in the hippocampus after traumatic brain injury
Keywords: CREB; Hippocampus; ERK; Traumatic brain injury
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Remote control of activity-dependent BDNF gene promoter-I transcription mediated by REST/NRSF
Keywords: BDNF; REST/NRSF; Calcium; HDAC; CREB; Transcription; Neuron
HTLV-2B Tax oncoprotein is modified by ubiquitination and sumoylation and displays intracellular localization similar to its homologue HTLV-1 Tax
Keywords: HTLV; Tax; CREB; NF-κB; Ubiquitination; Sumoylation; Nuclear bodies
Interleukin 2 and systemic lupus erythematosus: Beyond the transcriptional regulatory net abnormalities
Keywords: IL-2; Systemic lupus erythematosus; Transcriptional regulation; CREM; CREB
Why T waves change: A reminiscence and essay
Keywords: Cardiac memory; Ventricular pacing; Ion channel trafficking; Ion channel gene transcription; Transient outward potassium current; 4-AP; 4-aminopyridine; AP-1; activator protein-1; CREB; cyclic adenosine monophosphate response element binding protein;
Identification and characterization of an alternative promoter of the human PGC-1α gene
Keywords: PGC-1α gene; Alternative promoter; Skeletal muscle; Exercise; cAMP response element; E-box; Muscle-specific transcription factor; CREB;
A role for the extracellular signal-regulated kinase signal pathway in depressive-like behavior
Keywords: ERK; CREB; Hippocampus; Prefrontal cortex; U0126; Depression
Increased vascular permeability after cardiopulmonary bypass in patients with diabetes is associated with increased expression of vascular endothelial growth factor and hepatocyte growth factor
Keywords: 18; 29; CABG; coronary artery bypass grafting; CPB; cardiopulmonary bypass; CREB; cyclic adenosine monophosphate response element binding protein; CRP; C-reactive protein; DM; diabetes mellitus; EP300; E1A binding protein p300; HGF; hepatocyte growth fact
Levo-tetrahydropalmatine attenuates oxycodone-induced conditioned place preference in rats
Keywords: l-THP, (Levo-tetrahydropalmatine); ERK, (signal-regulated kinase); CREB, (cAMP responsive element binding protein); MEK, (Mitogen-activated protein kinase)Levo-tetrahydropalmatine; Oxycodone; CREB; ERK; Conditioned place preference
Lanthanum chloride impairs memory, decreases pCaMK IV, pMAPK and pCREB expression of hippocampus in rats
Keywords: Lanthanum; Memory; Hippocampus; CREB
Role of muscarinic signal transduction and CREB phosphorylation in dichlorvos-induced memory deficits in rats: An acetylcholine independent mechanism
Keywords: Organophosphate; Cholinesterases; Muscarinic receptors; Neurobehavior; Morris water maze; CREB
Long-term administration of green tea catechins prevents age-related spatial learning and memory decline in C57BL/6 J mice by regulating hippocampal cyclic amp-response element binding protein signaling cascade
Keywords: green tea catechins; learning and memory; Morris water maze; CREB; BDNF; Bcl-2ANOVA, analysis of variance; BDNF, brain-derived neurotrophic factor; CaMKII, Ca2+/calmodulin-dependent protein kinase II; CREB, cAMP-response element binding protein; EGC, (−)-
Preconditioning neuroprotection in global cerebral ischemia involves NMDA receptor-mediated ERK-JNK3 crosstalk
Keywords: CREB; cyclic adenosine monophosphate response element binding protein; ERK1/2; extracellular signal-regulated kinase 1/2; JNK; c-Jun-N-terminal kinase; NMDA; N-methyl-d-aspartate; MAPK; mitogen-activated protein kinases; TUNEL; terminal deoxynucleotidyl t
Simvastatin acutely reduces ischemic brain damage in the immature rat via Akt and CREB activation
Keywords: Statins; Neuroprotection; Neurodegeneration; Hypoxia ischemia; Akt; CREB; Neonate
Transcriptional regulation of the major zinc uptake protein hZip1 in prostate cancer cells
Keywords: BPH; Benign Prostatic Hyperplasia; ChIP; Chromatin Immunoprecipitation; EMSA; Electronic Mobility Shift Assay; GAPDH; Glyceraldehyde 3-phosphate Dehydrogenase; MTF1; Metal-activated Transcription Factor 1; PIN; Prostate Intra-epithelial Neoplasia; RACE; R
Early effects of high glucose in retinal tissue cultures: Renin-Angiotensin system-dependent and -independent signaling
Keywords: Angiotensin II; Diabetic retinopathy; RAS; Müller glia; Synapses; CREB; Akt; Enalaprilat; High glucose; Retinal neuroglial compartment;
The cAMP-responsive element binding protein (CREB) regulates the expression of acid ceramidase (ASAH1) in H295R human adrenocortical cells
Keywords: Acid ceramidase; cAMP; CREB; Ceramide; Sphingosine; Adrenocorticotropin
Differences in basal and morphine-induced FosB/ΔFosB and pCREB immunoreactivities in dopaminergic brain regions of alcohol-preferring AA and alcohol-avoiding ANA rats
Keywords: Selected rat lines; DeltaFosB; CREB; Morphine; Nicotine; Nucleus accumbens; Caudate-putamen; Prefrontal cortex
Differential gene expression in the rat hippocampus during learning of an operant conditioning task
Keywords: hippocampus; real-time PCR; learning; Arc; activity-regulated cytoskeleton-associated protein; BCIT; Box Control of Incompletely Trained; BCTr; Box Control of Trained; BDNF; brain-derived neurotrophic factor; C; Control; CamKII; Ca2+/calmodulin-dependent
Dual role of HIF-1α in delivering a survival or death signal in hypoxia exposed human K562 erythroleukemia cells
Keywords: HIF-1α; CREB; p38MAPK; Hypoxia; K562 erythroleukemia cells;
The anti-inflammatory target A3 adenosine receptor is over-expressed in rheumatoid arthritis, psoriasis and Crohn’s disease
Keywords: A3 adenosine receptor; ADORA3; Crohn’s disease; Psoriasis; Rheumatoid arthritis; NF-κB; CREB; PI3K-PKB/Akt; Inflammation
Activation of tyrosine hydroxylase prevents pneumonia in a rat chronic cerebral hypoperfusion model
Keywords: post-stroke pneumonia; dysphagia; cerebral hypoperfusion; neurotransmitters; phosphorylated-CREB; CBF; cerebral blood flow; CREB; cyclic AMP responsive element binding protein; ELISA; enzyme-linked immunosorbent assay; HPLC; high-performance liquid chroma
Protein receptor for activated C kinase 1 is involved in morphine reward in mice
Keywords: morphine; RACK1; CREB; SiRNACONC, control group with control plasmid; CONR, control group with SiRACK1 plasmid; CPP, conditioned place preference; CREB, cAMP-responsive element binding protein; DG, dentate gyrus; ERK, extracellular signal-regulated protei
Mirtazapine treatment after conditioning with methamphetamine alters subsequent expression of place preference
Keywords: Psychostimulants; Rat; Associative learning; Serotonin receptors; ERK; CREB; Pharmacotherapy;
Targeting glial physiology and glutamate cycling in the treatment of depression
Keywords: AANt; amino acid neurotransmitters; AMPA; alpha-amino-3-hydroxy-5-methyl-4-isoxazole-4-propionate; BDNF; brain-derived neurotrophic factor; CREB; cyclic AMP response element binding protein; CUS; chronic unpredictable stress; EAAT; excitatory amino acid t
Late phase of long-term potentiation induced by co-application of N-methyl-d-aspartic acid and the antagonist of NR2B-containing N-methyl-d-aspartic acid receptors in rat hippocampus
Keywords: chemically-induced late phase of LTP; NR2B antagonist; protein kinase A; protein synthesis; hippocampus; ACSF; artificial cerebrospinal fluid; AP5; 2-amino-5-phosphonovaleric acid; BDNF; brain-derived neurotrophic factor; CREB; cAMP-responsive element bin
Inhibitory effect of novel diallyldisulfide analogs on HMG-CoA reductase expression in hypercholesterolemic rats: CREB as a potential upstream target
Keywords: Diallyldisulfide; HMG-CoA reductase; SREBP-2; CREB; NF-Y; NF-κB
CREB is a key regulator of striatal vulnerability in chemical and genetic models of Huntington's disease
Keywords: Huntington's; CREB; 3-NP; Mouse; Transgenic; Striatum
In vivo role for CREB signaling in the noradrenergic differentiation of sympathetic neurons
Keywords: PKA; CREB; cAMP; Sympathetic; Noradrenergic; Tyrosine hydroxylase; Dopamine-β-hydroxylase
Research ReportValproic acid regulates catecholaminergic pathways by concentration-dependent threshold effects on TH mRNA synthesis and degradation
Keywords: SCFA; short chain fatty acid; SB; sodium butyrate; VPA; valproic acid; TH; tyrosine hydroxylase; PC12; pheochromocytoma cell line; mRNA; messenger RNA; rRNA; ribosomal RNA; CREB; cAMP response element binding protein; AP-1; activator protein; DBH; dopamin
Signaling pathways in PACAP regulation of VIP gene expression in human neuroblastoma cells
Keywords: PACAP; Signaling; Gene expression; FOS; VIP; Phosphorylation; Protein kinase; CREB; ERK
Chronic but not acute foot-shock stress leads to temporary suppression of cell proliferation in rat hippocampus
Keywords: affective disorders; DCX; glucocorticoids; neurogenesis; neuronal plasticity; ultrasonic vocalization; ACTH; adrenocorticotropic hormone; AS; acutely stressed; BDNF; brain-derived neurotrophic factor; BrdU; bromodeoxyuridine; CORT; corticosterone; CREB; c
Neural ectoderm-secreted FGF initiates the expression of Nkx2.5 in cardiac progenitors via a p38 MAPK/CREB pathway
Keywords: VMZ; ventral marginal zone; DMZ; dorsal marginal zone; AC; animal cap; AMO; antisense morpholino oligonucleotide; MAPK; mitogen-activated protein kinase; Cardiac gene expression; Nkx2.5; FGF; p38 MAPK; CREB; Xenopus laevis;
Mechanisms for suppression of interleukin-6 expression in peritoneal macrophages from docosahexaenoic acid-fed mice
Keywords: Deoxynivalenol (DON); Interleukin-6; DHA; CREB; Macrophage; Protein kinase
Targeting the ghrelin receptor to regulate food intake
Keywords: AgRP; agouti-related peptide; AMPK; AMP-activated protein kinase; AP; area postrema; ARC; arcuate nucleus; CART; cocaine- and amphetamine-regulated transcript; CPT-1; carnitine-palmitoyltransferase 1; CREB; cAMP responsive element binding protein; GABA; Î
Regulation of CART peptide expression by CREB in the rat nucleus accumbens in vivo
Keywords: CREB; CART peptide; Psychostimulant; Nucleus accumbens
Cyclic AMP regulates extracellular matrix gene expression and metabolism in cultured primary rat chondrocytes
Keywords: AC; adenylyl cyclase; Act D; actinomycin D; Agc1; aggrecan; ANOVA; analysis of variance; cAMP; cyclic 3â², 5â²-adenosine monophosphate; cGK; cyclic guanine monophosphate-dependent protein kinase; Col2a1; type II collagen; Col10a1; type X collagen; CPT-c
Preconditioning with 4-aminopyridine protects cerebellar granule neurons against excitotoxicity
Keywords: 4-Aminopyridine; Cerebellar granule neuron; Excitotoxicity; Glutamate; Neuroprotection; CREB; 3-Nitropropionic acid; NMDA receptor
Type I Insulin-like Growth Factor Receptor Induces Pulmonary Tumorigenesis
Keywords: AAH; adenomatous alveolar hyperplasia; BASC; bronchioalveolar stem cell; CREB; cyclic adenosine monophosphate response element binding protein; CCSP; Clara cell secretory protein; IGF; insulin-like growth factor; IGFBP; insulin-like growth factor binding
Sex differences in stress responses: Focus on ovarian hormones
Keywords: Estrogen; Gender; Neuroplasticity; Chronic stress; Female rat; Fos; CREB; ERK1/2; Behavior
DFP initiated early alterations of PKA/p-CREB pathway and differential persistence of β-tubulin subtypes in the CNS of hens contributes to OPIDN
Keywords: Organophosphate-induced delayed neurotoxicity; OPIDN; PKA; CREB; pCREB; β-Tubulins; Neurodegeneration; Diisopropylphosphorofluoridate; Anticholinergics. Central nervous system; Peripheral nervous system
Noradrenergic neurons in the locus coeruleus contribute to neuropathic pain
Keywords: CREB; Fos; norepinephrine; saporin; dopamine β hydroxylase; ratDβH, dopamine-β-hydroxylase; ir, immunoreactive; LC, locus coeruleus; MMP, machine-mounted probe; NE, norepinephrine; pCREB, phosphorylated cAMP response element-binding protein; PMCC, product
p16INK4a Is a β-Catenin Target Gene and Indicates Low Survival in Human Colorectal Tumors
Keywords: ACF; aberrant crypt foci; APC; adenomatous polyposis coli; CBP; CREB-binding protein; CREB; cAMP response element-binding; CNAPI; chromosome condensation-related SMC-associated protein; NCAPD2; non-SMC condensin I complex; subunit D2 CRC; colorectal cance
Pretreatment with a single estradiol-17β bolus activates cyclic-AMP response element binding protein and protects CA1 neurons against global cerebral ischemia
Keywords: in vivo; signal transduction; cerebral blood flow; neuroprotection; cyclic-AMP response element binding protein; hormone replacement therapy; Akt; protein kinase B; Bcl-2; B-cell leukemia/lymphoma 2; CaMKII; calcium-calmodulin-dependent protein kinase;
Neural phosphoproteomics of a chronic hypoxia model-Lymnaea stagnalis
Keywords: proteomics; phosphorylation; hypoxia tolerance; Pro-Q Diamond; electrophysiology; behavior; Akt; protein kinase B; AP; action potential; APD50; action potential duration measured as the time from the overshoot to 50% repolarization to resting potential; C
CCL3L1 prevents gp120-induced neuron death via the CREB cell signaling pathway
Keywords: CCL3L1; CREB; Bcl-2; CCR5; Apoptosis; Neuroprotection
Viral vector approaches to modify gene expression in the brain
Keywords: Viral vectors; Synaptic plasticity; Learning and memory; Drug addiction; AMPAR; CREB
Calcium influx into MIN6 insulinoma cells induces expression of Egr-1 involving extracellular signal-regulated protein kinase and the transcription factors Elk-1 and CREB
Keywords: Ca2+; CREB; Egr-1; Elk-1; Insulinoma cells; MKP-1; Serum response element; Ternary complex factor
Genistein treatment of cells inhibits arenavirus infection
Keywords: Arenavirus; Lassa virus; Pichindé virus; Genistein; CREB; ATF-2
DPPC regulates COX-2 expression in monocytes via phosphorylation of CREB
Keywords: Pulmonary surfactant; Inflammation; DPPC; COX-2; CREB