Keywords: Human pluripotent stem cells; Embryonic stem cells; Single-cell cloning; Induced pluripotent stem cells; hPSCs; hESCs; Genome engineering; CRISPR-Cas9;
مقالات ISI (ترجمه نشده)
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Keywords: Cancer; Immunotherapy; Nanomedicine; Dendritic cell vaccine; CAR-T; CRISPR-Cas9; Tumor associated macrophages; PD-1/PDL-1 targeting; CTLA-4 targeting; Cytokine storm;
Keywords: TGCTs; testicular germ cell tumors; GCNIS; germ cell neoplasia in situ; ESCs; embryonic stem cells; ECCs; embryonal carcinoma cells; PGCs; primordial germ cells; IGCNU; Intratubular germ cell neoplasia of the unclassified type; CIS; Carcinoma in Situ; hPG
Keywords: Inflammation; Nanoparticles; Surface properties; Neutrophils; CRISPR-Cas9;
Keywords: AAV; adeno-associated viruses; AMS; activated macrophage suspension; Ang; angiopoietin; APC; activated protein C; antimiRs; miRNA antisense oligonucleotides; bFGF; basic FGF; BM; bone marrow; cDNA; complementary DNA; CLI; critical limb ischemia; CRISPR-Ca
Keywords: Luciferase reporter assay; Jurkat; IL-2 promoter; CRISPR-Cas9;
Keywords: CRISPR-Cas9; ARID1A; Transcription regulation;
Keywords: CRISPR-Cas9; Kluyveromyces lactis; Kluyveromyces marxianus; Scheffersomyces stipitis; Yarrowia lipolytica; Hansenula polymorpha; Pichia pastoris; HR; homologous recombination; NHEJ; nonhomologous end-joining; DSB; double strand break; CRISPR; Clustered re
Keywords: Secondary metabolism; Genome editing; TALEN; CRISPR-Cas9; Hybrid metabolites; Epigenome editing;
Keywords: CRISPR-Cas9; Gene editing; High-content analysis screen; Synthetic crRNA; Arrayed crRNA libraries; Cell cycle regulators;
Keywords: BAL; bronchoalveolar lavage; ChIA-PET; chromatin interaction analysis with paired-end tag; ChIP-seq; chromatin inmunoprecipitation and massively parallel sequencing; circ-ncRNA; circulating noncoding RNA; CRC; colorectal cancer; CRISPR-Cas9; clustered, re
Keywords: 6-OHDA; 6-hydroxydopamine; Aβ; amyloid-β; AD; Alzheimer disease; ALS; amyotrophic lateral sclerosis; APOE4; apolipoprotein E4; APP; amyloid precursor protein; ASCL1; achaete-scute family basic helix-loop-helix transcription factor 1; ATP; adenosine trip
Keywords: KIV; 2-ketoisovalerate; KMV; 2-keto-3-methyl-valerate; TCA; tricarboxylic acid; FAMEs; fatty acid methyl esters; FAEEs; fatty acid ethyl esters; FFAs; Free fatty acids; ACP; acyl carrier protein; AccABCD; ATP-dependent-acetyl-CoA carboxylase; PKS; Polyket
Keywords: ETC; electron transport complexes; ROS/RNS; reactive oxygen or nitrogen spices; âÏm; mitochondrial inner membrane potential; TCA; TriCarboxylic acid cycle; MPTP; mitochondrial permeability transition pore; mtDNA; mitochondrial DNA; ND5; NADH dehydrogen
Keywords: new plant breeding techniques; cisgenesis; intragenesis; TALEN; CRISPR-Cas9; early flowering
Keywords: DSB; double-strand break; HR; homologous recombination; HDR; homology-directed repair; BIR; break-induced replication; NHEJ; nonhomologous end-joining; Alt-NHEJ; alternative-NHEJ; MMEJ; microhomology-mediated end-joining; ssDNA; single-stranded DNA; Doubl
Keywords: Human stem cells; iPSC models; Drug discovery; CRISPR-Cas9; High-throughput screening; High-content imaging; Neuropharmacology; Bipolar disorder; Schizophrenia; Autism spectrum disorders; Dementia;
Keywords: rewilding; reverse breeding; organic agriculture; TALEN; CRISPR-Cas9; cisgenesis
Keywords: A; adenine; ACMG; American College of Medical Genetics; Ala; alanine; Asp; aspartic acid; BCL2L12; B-cell lymphoma-2-like protein 12; BRCA1; breast cancer-1 gene; C; cytosine; CCDS; Consensus Coding Sequence; CD; circular dichroism; CDC; coding sequence;
Keywords: Genetic modified (GM) food; Transgenic; Safety; DNA; CRISPR-Cas9
Targeted knockout of phospholipase A2 to increase lipid productivity in Chlamydomonas reinhardtii for biodiesel production
Keywords: Chlamydomonas reinhardtii; Biofuel; Triacylglycerol; Phospholipase; CRISPR-CAS9;
Effective regeneration of dystrophic muscle using autologous iPSC-derived progenitors with CRISPR-Cas9 mediated precise correction
Keywords: CRISPR-Cas9; Precise correction; DMD; Myogenic progenitor cells; Myogenesis;
Generation of and characterization of anti-IL-11 antibodies using newly established Il11-deficient mice
Keywords: Interleukin 11; Proliferation; STAT3; CRISPR-Cas9; Knockout mice; CRISPR; Clustered regularly interspaced short palindromic repeats; STAT; Signal transducer and activator of transcription; AOM; Azoxymethane; DSS; dextran sulfate sodium; IL; Interleukin; J
SKLPT imaging: Efficient in vivo pre-evaluation of genome-editing modules using fluorescent protein with peroxisome targeting signal
Keywords: CRISPR-Cas9; Fluorescent reporter; GFP; PTS1; TALEN; ZFN;
HDAC8 regulates neural differentiation through embryoid body formation in P19â¯cells
Keywords: Cell cycle; CRISPR-Cas9; HDAC8; HDAC8-Selective inhibitor; NCC-149; Neurodevelopment; CdLS; Cornelia de Lange syndrome; EB; embryoid body; ES cells; embryonic stem cells; FGF8; fibroblast growth factor 8; HDAC; histone deacetylase; HDAC8i; HDAC8-selective
Determination of EPAC2 function using EPAC2 null Min6 sublines generated through CRISPR-Cas9 technology
Keywords: CRISPR-Cas9; Min6; EPAC2; Diabetes; β cells; Insulin secretion; Sulfonylurea;
In silico sgRNA tool design for CRISPR control of quorum sensing in Acinetobacter species
Keywords: AbaI; Acinetobacter baumannii; CHOPCHOP; Crispr-cas9; sgRNA;
Adeno-associated virus-mediated delivery of CRISPR-Cas9 for genome editing in the central nervous system
Keywords: Adeno-associated virus (AAV); CRISPR-Cas9; Therapeutic applications; Genome engineering; Central nervous system;
Phenotypic novelty by CRISPR in plants
Keywords: Plant biotechnology; Plant development; CRISPR-Cas9; Proteostasis; Epigenome; Allelic variation;
Dissecting the signaling features of the multi-protein complex GPCR/β-arrestin/ERK1/2
Keywords: GPCRs; G protein-coupled receptors; TM; transmembrane; ECLs; extracellular loops; ICLs; intracellular loops; GRKs; G protein-coupled receptor kinases; MAPKs; mitogen activated protein kinases; ERK1/2; extracellular signal-regulated kinases 1 and 2; JNK; c
Genome engineering of Clostridium difficile using the CRISPR-Cas9 system
Keywords: Clostridium difficile; Clostridium difficile infection (CDI); CRISPR-Cas9; Genome engineering; Infectious disease; PpFbFPm; spo0A; Sporulation;
Technological advances in integrating multi-kilobase DNA sequences into genomes
Keywords: Gene editing; Targeted integration; CRISPR-Cas9; Genome engineering; Non-homologous end joining; Homologous recombination;
Mini-review on CRISPR-Cas9 and its potential applications to help controlling neglected tropical diseases caused by Trypanosomatidae
Keywords: CRISPR-Cas9; Trypanosomatidae; Parasites; Neglected tropical diseases;
CRISPR-Cas9-mediated gene editing in human MPS I fibroblasts
Keywords: Hurler syndrome; Mucopolysaccharidosis; Gene editing; CRISPR-Cas9;
CRISPR/Cas9-mediated editing of GABRR2 gene in RGC-5 cells induces random exon deletion, exon splicing and new exon recruitment
Keywords: CRISPR-Cas9; GABRR2; RGC-5; Exon skipping; Exon recruitment;
Genetic engineering in primary human B cells with CRISPR-Cas9 ribonucleoproteins
Keywords: CRISPR-Cas9; Cas9 ribonucleoprotein; Primary human B cells; Genome engineering;
Efficient oligo nucleotide mediated CRISPR-Cas9 gene editing in Aspergilli
Keywords: CRISPR-Cas9; Genetic engineering; Gene editing; Filamentous fungi; Aspergillus;
CUEDC1 is a primary target of ERα essential for the growth of breast cancer cells
Keywords: Cancer; Enhancer; Breast; CRISPR-Cas9;
CRISPR-Cas9 based plant genome editing: Significance, opportunities and recent advances
Keywords: Cisgenics; CRISPR-Cas9; Gene editing; Mutations; Marker free transgenics;
CRISPR-Cas9 system-driven site-specific selection pressure on Herpes simplex virus genomes
Keywords: CRISPR-Cas9; HSV-1; Viral genome replication; Selection pressure; Site-specific mutation;
The activation of STIM1 mediates S-phase arrest and cell death in paraquat induced acute lung intoxication
Keywords: ALI; acute lung injury; 2-APB; 2-Aminoethoxydiphenyl borate; BSA; bovine serum albumin; CCNA/CCND/Cyclin A/D; mammalian A/D-type Cyclin; CDK; Cyclin dependent kinase; CKI; Cyclin dependent kinase inhibitor; CRISPR-CAS9; clustered regularly interspaced sho
Exploiting endogenous CRISPR-Cas system for multiplex genome editing in Clostridium tyrobutyricum and engineer the strain for high-level butanol production
Keywords: Endogenous CRISPR-Cas system; CRISPR-Cas9; CRISPR-Cpf1; Clostridium tyrobutyricum; Multiplex genome editing; Butanol;
CRISPR-Cas9 genome engineering: Treating inherited retinal degeneration
Keywords: Genome engineering; CRISPR-Cas9; Induced pluripotent stem cells; Retinal degeneration; Transplantation;
Temperature effect on CRISPR-Cas9 mediated genome editing
Keywords: CRISPR-Cas9; Hyperthermia; Genome editing; Mammalian cells;
Regular ArticlesComparison of genome engineering using the CRISPR-Cas9 system in C. glabrata wild-type and lig4 strains
Keywords: Candida glabrata; CRISPR-Cas9; Non-homologous end Joining;
Fundamental CRISPR-Cas9 tools and current applications in microbial systems
Keywords: CRISPR-Cas9; CRISPR interference; CRISPR activation; DNA repair; Homologous recombination;
Generation of chromosomal translocations that lead to conditional fusion protein expression using CRISPR-Cas9 and homology-directed repair
Keywords: Double-strand break; HDR; Chromosomal translocation; CRISPR-Cas9; EWSR1-WT1;
Gene editing in T cell therapy
Keywords: Gene editing; CRISPR-Cas9; T cells;
Automated microraft platform to identify and collect non-adherent cells successfully gene-edited with CRISPR-Cas9
Keywords: Microraft; Cell array; CRISPR-Cas9; Cytometry; Cell sorting;
A comparison of Agrobacterium-mediated transformation and protoplast-mediated transformation with CRISPR-Cas9 and bipartite gene targeting substrates, as effective gene targeting tools for Aspergillus carbonarius
Keywords: Protoplast; Agrobacterium; CRISPR-Cas9; Transformation; Homologous recombination; Fungi;