دانلود مقالات ISI درباره Crispr + ترجمه فارسی

Efficient transgene insertion in a pseudorabies virus vector by CRISPR/Cas9 and marker rescue-enforced recombination

Keywords: ASFV; African swine fever virus; BAC; bacterial artificial chromosome; Cas9; CRISPR associated protein 9; CRISPR; clustered regularly interspaced short palindromic repeats; DSB; double strand break; EGFP; enhanced green fluorescent protein; FBS; fetal bov

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

The interaction of IGF-1/IGF-1R and hydrogen sulfide on the proliferation of mouse primary vascular smooth muscle cells

Keywords: BrdU; bromodeoxyuridine; CBS; cystathionine-beta-synthase; CRISPR; clustered regularly interspaced short palindromic repeats; CSE; cystathionine-gamma-lyase; DMEM; dulbecco's modified eagle's medium; ERK; extracellular regulated protein kinase; FBS; f

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Metabolic engineering of Saccharomyces cerevisiae by using the CRISPR-Cas9 system for enhanced fatty acid production

Keywords: Fatty acids; Cas9; Saccharomyces cerevisiae; CRISPR; Isocitrate dehydrogenase; ATP-citrate lyase;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

CRISPR-engineered genome editing for the next generation neurological disease modeling

Keywords: Neurological disorder; Brain tumor; Mouse model; CRISPR; Cas9;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Characterization of WDR20: A new regulator of the ERAD machinery

Keywords: ERAD; WDR20; TCRα; p97; CRISPR; HRD1;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

The contributions of individual galactosyltransferases to protein specific N-glycan processing in Chinese Hamster Ovary cells

Keywords: CHO cells; Chinese Hamster Ovary cells; CRISPR; clustered regularly interspaced short palindromic repeat; sgRNA; single guide RNA; ST3GAL; alpha-2,3-sialyltransferase; ST6GAL; alpha-2,6-sialyltransferase; EPO; erythropoietin; Fc; Fragment crystallizable;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Metabolic pathway interruption: CRISPR/Cas9-mediated knockout of tryptophan 2,3-dioxygenase in Tribolium castaneum

Keywords: CRISPR; Ommochrome; Tryptophan 2,3-dioxygenase; Vermilion; Tribolium castaneum; Insect eye pigment;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Biotechnology Challenges to In Vitro Maturation of Hepatic Stem Cells

Keywords: Liver Development; Differentiation; Hepatocyte; Culture; CRISPR; clustered regularly interspaced short palindromic repeats; CYP; cytochrome P450; 3D; 3-dimensional; DNMTi; DNA methylation inhibitor; ECM; extracellular matrix; ESC; embryonic stem cell; ES-

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Comparison of advanced whole genome sequence-based methods to distinguish strains of Salmonella enterica serovar Heidelberg involved in foodborne outbreaks in Québec

Keywords: Foodborne outbreaks; Salmonella Heidelberg; Core genome SNV; Core/whole genome MLST; CRISPR; PFGE;

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

H2S protects lipopolysaccharide-induced inflammation by blocking NFκB transactivation in endothelial cells

Keywords: H2S; Cystathionine gamma-lyase; LPS; Endothelial cells; Inflammation; NFκB; ChIP; chromatin immunoprecipitation; CRISPR; clustered regulatory interspersed short palindromic repeats; CSE; Cystathionine gamma-lyase; H2S; Hydrogen sulfide; HUVEC; Human umbi

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Design rules of synthetic non-coding RNAs in bacteria

Keywords: Non-coding RNA; Antisense RNA; STAR; Toehold switch; CRISPR; Aptazyme;

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

Evaluating different DNA binding domains to modulate L1 ORF2p-driven site-specific retrotransposition events in human cells

Keywords: AAV; Adeno-Associated Virus; CRISPR; clusters of regularly interspaced short palindromic repeats; DBDs; DNA binding domains; gRNA; guide RNA; HAC; homology Arm Cassette; HRP; Horse Radish Peroxidase; PAM; Protospacer Adjacent Motif; TAL; Transcription act

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Metabolic engineering to enhance heterologous production of hyaluronic acid in Bacillus subtilis

Keywords: Metabolic engineering; Hyaluronic acid; Hyaluronan; CRISPR; Bacillus subtilis; Transcriptional interference;

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2018 سفارش ترجمه

The potential for targeted rewriting of epigenetic marks in COPD as a new therapeutic approach

Keywords: COPD; Chronic obstructive pulmonary disease; CRISPR; Clustered Regularly Interspaced Short Palindromic Repeats; CRISPR/Cas9; Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR-Associated Protein 9 (Cas9); CSC; Cigarette smoke co

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2018 سفارش ترجمه

Reformation in chimeric antigen receptor based cancer immunotherapy: Redirecting natural killer cell

Keywords: NK cell; natural killer cell; IFN-γ; interferon-γ; IL; interleukin; TNF-α; tumor necrosis factor-α; CCL; C-C motif ligand; GM-CSF; granulocyte-macrophage colony-stimulating factor; ADCC; antibody dependent cell-mediated cytotoxicity; TRAIL; TNF-relate

دانلود رایگان متن کامل مقاله ISI 69 صفحه سال انتشار : 2018 سفارش ترجمه

Generation of SMURF2 knockout human cells using the CRISPR/Cas9 system

Keywords: SMURF2; CRISPR/Cas9; Knockout; Human cells; SMURF2; Smad Ubiquitination Regulatory Factor 2; HECT; homologous to E6-AP COOH-terminus; CRISPR; clustered regularly interspaced short palindromic repeats; Cas9; CRISPR-associated protein 9; ZFNs; zinc finger n

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

Draft genome sequence of Thalassobius gelatinovorus CECT 4357T, a roseobacter with the potential ability to degrade polycyclic aromatic hydrocarbons

Keywords: PHB; poly-β-hydroxybutyrate; CRISPR; clustered regularly interspaced short palindromic repeats; COG; clusters of orthologous genes; Rhodobacteraceae; Strictly aerobic; PHB; Ectoine; Aromatic compounds; Gelatinase;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Adaptation of CRISPR nucleases for eukaryotic applications

Keywords: CRISPR; Genome editing; Cas9; Cpf1; C2cx;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Genome-scale CRISPR pooled screens

Keywords: Genome engineering; Genetic screens; CRISPR; Cas9; Noncoding; Cancer; RNAi; RNA interference; CRISPR; clustered regularly interspaced short palindromic repeats; sgRNA; single-guide RNA; DSB; double-strand break; NHEJ; non-homologous end-joining; PCR; poly

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Transcriptional activation of the MICA gene with an engineered CRISPR-Cas9 system

Keywords: MICA; CRISPR; microRNA; Transcriptional activation;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

PAF53 is essential in mammalian cells: CRISPR/Cas9 fails to eliminate PAF53 expression

Keywords: Ribosomal RNA; Nucleolus; RNA polymerase I; rDNA; PAF53; A49; CRISPR/Cas9; Transcription; rDNA; ribosomal DNA; sgRNA; small guide RNA; CRISPR; clustered regularly interspaced short palindromic repeats; Cas9; CRISPR-associated protein-9 nuclease; Pol I; RN

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Regular ArticlesEstablishment of CRISPR/Cas9 in Alternaria alternata

Keywords: Alternaria; Knock-out; CRISPR; Uracil;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Methods for decoding Cas9 protospacer adjacent motif (PAM) sequences: A brief overview

Keywords: HEase; homing endonuclease; ZFN; zinc finger nuclease; TALEN; TAL-effector nuclease; DSB; double strand break; dCas9; catalytically inactive (dead) Cas9; RNP; ribonucleoprotein; Genome editing; CRISPR; Cas9; High-throughput methods; PAM library;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Genetic analysis of Salmonella enterica serovar Gallinarum biovar Pullorum based on characterization and evolution of CRISPR sequence

Keywords: CRISPR; Salmonella enterica serovar Gallinarum biovar Pullorum (S. Pullorum); SNP; Whole-genome single-nucleotide polymorphism typing (WGST);

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

A two-plasmid inducible CRISPR/Cas9 genome editing tool for Clostridium acetobutylicum

Keywords: aTc; anhydrotetracycline; CRISPR; Clustered regularly interspaced short palindromic repeats; Cas; CRISPR-associated proteins; Cas9n; Cas9 nickase; DSB; Double-strand break; gDNA; genomic DNA; gRNA; guide RNA; HR; Homologous recombination; NHEJ; Non-homolo

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

An efficient system for deletion of large DNA fragments in Escherichia coli via introduction of both Cas9 and the non-homologous end joining system from Mycobacterium smegmatis

Keywords: CRISPR; NHEJ; Genome editing; Large fragment deletion; E. coli;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Detection and CRISPR subtyping of Salmonella spp. isolated from whole raw chickens in Yangzhou from China

Keywords: Salmonella; MPN; CRISPR; Poultry;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Edited course of biomedical research: leaping forward with CRISPR

Keywords: CRISPR; Cas9; Cas13a; Gene modification; Gene modulation; CRISPR imaging; CRISPRi; CRISPRa; dCas9;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Mini-reviewApplication of CRISPR-mediated genome engineering in cancer research

Keywords: CRISPR; Cas9; Genome engineering; Cancer; Mouse models;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

ReviewInvestigating Leber's hereditary optic neuropathy: Cell models and future perspectives

Keywords: CRISPR; Clustered Regularly Interspaced Short Palindromic Repeats; EBV; Epstein Barr virus; LHON; Leber's hereditary optic neuropathy; RGC; retinal ganglion cells; EtBr; ethidium bromide; mitoTALENs; mitochondria targeted transcription-activator-like effe

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Analysis of prevalence and CRISPR typing reveals persistent antimicrobial-resistant Salmonella infection across chicken breeder farm production stages

Keywords: Salmonella; Prevalence; Antimicrobial resistance; CRISPR; Breeder farm;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Precision genome editing using CRISPR-Cas9 and linear repair templates in C. elegans

Keywords: Genome editing; CRISPR; C. elegans; Cas9 RNP; Linear repair templates; Short homology; Gene conversion; Homology-dependent repair (HDR);

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Assessing the intra-species genetic variability in the clonal pathogen Campylobacter fetus: CRISPRs are highly polymorphic DNA markers

Keywords: Campylobacter fetus; CRISPR; Genetic variability;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

The completely annotated genome and comparative genomics of the Peptoniphilaceae bacterium str. ING2-D1G, a novel acidogenic bacterium isolated from a mesophilic biogas reactor

Keywords: SignalP; signal peptides; TMHMM; transmembrane helices hidden markov models; CRISPR; clustered regularly interspaced short palindromic repeats; Peptoniphilaceae; Anaerobic digestion; Biogas production; Metabolic pathway reconstruction; Acidogenesis;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Analysing the outcome of CRISPR-aided genome editing in embryos: Screening, genotyping and quality control

Keywords: CRISPR; clustered regularly interspaced short palindromic repeat; Cas9; CRISPR associated 9; ddPCR; droplet digital polymerase chain reaction; DNA; deoxy-nucleotide acid; DSB; double stranded break; HDR; homology directed repair; indel; insertion/deletion

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Store-operated calcium entry is dispensable for the activation of ERK1/2 pathway in prostate cancer cells

Keywords: EGF; epidermal growth factor; ER; endoplasmic reticulum; ERK; extracellular signal-regulated kinase; JNK; c-Jun N-terminal kinase; MAPK; mitogen-activated protein kinase; SOCE; store-operated calcium entry; Tg; thapsigargin; Calcium; CRISPR; ERK1/2; SOCE;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

High-fidelity Glucagon-CreER mouse line generated by CRISPR-Cas9 assisted gene targeting

Keywords: Islet; α-cell; Enteroendocrine L-cell; Glucagon; GLP1; CRISPR; Cre; Cre recombinase; CreERT2; tamoxifen-inducible Cre recombinase-estrogen receptor fusion protein; CRISPR; clustered regularly interspaced short palindromic repeat; DAPI; 4′,6-diamidino-2

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Research paperGlobal transcriptome analysis of Halolamina sp. to decipher the salt tolerance in extremely halophilic archaea

Keywords: ABC; ATP-binding cassette; Cas; CRISPR-associated protein; COGs; Cluster of Orthologous Groups; CRISPR; Clustered regularly interspaced short palindromic repeats; DEG; Differentially expressed gene; GO; Gene Ontology; KEGG; Kyoto Encyclopedia of Genes and

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

The application of CRISPR technology to high content screening in primary neurons

Keywords: High content screening; CRISPR; Cortical neuron; PTEN;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Research review paperDetection of on-target and off-target mutations generated by CRISPR/Cas9 and other sequence-specific nucleases

Keywords: CRISPR; Cas9; Genome editing; Engineered nucleases; Indel detection; Unbiased off-target analysis; Mismatch detection assays;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Review articleThe AAV-mediated and RNA-guided CRISPR/Cas9 system for gene therapy of DMD and BMD

Keywords: DMD; Duchenne muscular dystrophy; BMD; Becker muscular dystrophy; Dmd; the dystrophin gene; CRISPR; clustered regularly interspaced short palindromic repeats; Cas9; CRISPR-associated protein 9; gRNAs; guided RNAs; SpCas9; Cas9 from Staphylococcus pyogenes

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

BIBAC-GW-based vectors for generating reporter lines for site-specific genome editing in planta

Keywords: BIBAC; Binary vector based on Bacterial artificial chromosomes; ChIP; Chromatin ImmunoPrecipitation; CRISPR; Clustered Regularly-Interspaced Short Palindromic Repeat; GW; Gateway; NLS; nuclear localization signal; Nos; Nopaline Synthase; ODM; Oligonucleot

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Enhanced CRISPR/Cas9-mediated precise genome editing by improved design and delivery of gRNA, Cas9 nuclease, and donor DNA

Keywords: CRISPR; clustered regularly interspaced short palindromic repeats; CAS9; CRISPR associated protein; gRNA; guide RNA; PAM; protospacer adjacent motif; RNP; ribonucleoprotein; HDR; homology directed repair; hESCs; human embryonic stem cells; NHEJ; non-homol

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Key elements for designing and performing a CRISPR/Cas9-based genetic screen

Keywords: CRISPR; Cas9; Genetic screen;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Systematic Analysis of Known and Candidate Lysine Demethylases in the Regulation of Myoblast Differentiation

Keywords: H3K4me1; H3 lysine 4 monomethylation; H3K27ac; H3K27 acetylation; KMT; lysine methyltransferase; KDM; lysine demethylase; CRISPR; cluster regulatory interspaced short palindromic repeats; sgRNA; small guide RNA; myHC; myosin heavy chain; ALP; alkaline pho

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

ReviewPanacea in progress: CRISPR and the future of its biological research introduction

Keywords: CRISPR; Antimicrobials; Antibiotic resistance; Genome editing; Bacteriophage;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Ltbp4 regulates Pdgfrβ expression via TGFβ-dependent modulation of Nrf2 transcription factor function

Keywords: ARE; antioxidant response elements; CHX; cycloheximide; CM; conditioned media; COPD; chronic obstructive pulmonary disease; CRISPR; clustered regularly interspaced short palindromic repeats; ECM; extracellular matrix; GCLC; Glutamate-cysteine ligase catal

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Do Animal Models of Acute Pancreatitis Reproduce Human Disease?

Keywords: Acute Pancreatitis; Animal Models; Caerulein; Alcohol; CRISPR; clustered regularly interspaced short palindromic repeats; ERCP; endoscopic retrograde cholangiopancreatography; LPS; lipopolysaccharide; NNK; 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone; P

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Permissiveness of human hepatocellular carcinoma cell lines for hepatitis C virus entry and replication

Keywords: HCV; hepatitis C virus; pegIFN-α; pegylated interferon alpha; DAAs; direct acting antivirals; BCLC; Barcelona Clínic Liver Cancer; IF; immunofluorescence; HCVpp; HCV pseudoparticles; HCVcc; HCV cell culture; JFH1; Japanese fulminant hepatitis 1; Apo; ap

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Simplified CRISPR tools for efficient genome editing and streamlined protocols for their delivery into mammalian cells and mouse zygotes

Keywords: Genome editing; CRISPR; Cas9; crRNA-tracrRNA; Ribonucleoprotein (RNP) complex; Homology directed repair (HDR);

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه