Stromal cell derived factor-1, CXCR4 and CXCR7 gene transcripts in pterygia
Keywords: Pterygium; SDF-1; CXCR4; CXCR7; Angiogenesis;
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Chemokines and cocaine: CXCR4 receptor antagonist AMD3100 attenuates cocaine place preference and locomotor stimulation in rats
Keywords: Chemokine; CXCL12; SDFâ1α; CXCR4; AMD 3100; Plerixafor; Cocaine; Psychostimulant; Conditioned place preference; Addiction;
Association of CXCR4, CCR7, VEGF-C and VEGF-D expression with lymph node metastasis in patients with cervical cancer
Keywords: Cervical cancer; Lymph node metastasis; CXCR4; CCR7; VEGF-C; VEGF-D;
Association of CXCR4 expression with coronary collateralization in patients with chronic total coronary occlusion: A nested case-control study
Keywords: Coronary collateralization; CXCR4; Chronic total coronary occlusion; Nested case-control study;
Discordant mRNA and protein expression of CXCR4 under in vitro CoCl2-induced hypoxic conditions
Keywords: Cobalt chloride; CXCR4; Retinal ischemia; Retinoblastoma; Human umbilical vein endothelial cells;
A randomized phase II study of LY2510924 and carboplatin/etoposide versus carboplatin/etoposide in extensiveâdisease small cell lung cancer
Keywords: CXCR4; LY2510924; Extensive-disease small cell lung cancer; Phase II trial;
Chemokine receptor CCR5 and CXCR4 might influence virus replication during IBDV infection
Keywords: CCR5; CXCR4; Infectious bursal disease virus; T cell migration;
Chondrogenic progenitor cells promote vascular endothelial growth factor expression through stromal-derived factor-1
Keywords: SDF-1α; CXCR4; Vascular endothelial growth factor (VEGF); Chondrogenic progenitor cells (CPCs); p38 MAPK;
Evaluating the methylation status of CXCR4 promoter: A cost-effective and sensitive two-step PCR method
Keywords: CXCR4; Promoter; Epigenetics; DNA methylation; qPCR; SYBR green;
Original ArticleAMD3100 Accelerates Reendothelialization of Neointima in Rabbit Saccular Aneurysm After Flow Diverter Treatment
Keywords: AMD3100; Endothelial-like cells; Flow diverter treatment; Saccular aneurysm; CXCR4; CXC chemokine receptor 4; DSA; Digital subtraction angiography; EPC; Endothelial progenitor cells; FD; Flow diverter; GAPDH; Glyceraldehyde phosphate dehydrogenase; KDR; K
Species-specific real-time RT-PCR analysis of expression of stromal cell genes in a tumor xenotransplantation model in mice
Keywords: Glioma; Tumor stroma; Dipeptidyl peptidase; Fibroblast activation protein; CXCR4; Species-specific expression;
miR-381 inhibited breast cancer cells proliferation, epithelial-to-mesenchymal transition and metastasis by targeting CXCR4
Keywords: miR-381; Breast cancer; CXCR4; Proliferation; EMT; Metastasis;
Monomeric CXCL12 outperforms its dimeric and wild type variants in the promotion of human endothelial progenitor cells' function
Keywords: CXCL12; CXCR4; CXCR7; Endothelial progenitor cells; Monomer;
Curcumin synergizes with the endocannabinoid reuptake inhibitor OMDM-2 in human MCF-7 breast cancer and U-87 glioblastoma cells
Keywords: Î9-THC; Delta-9-tetrahydrocannabinol; 2-AG; 2-arachidonoylglycerol; AEA; Anandamide; BCL2; B-cell CLL/lymphoma 2; CB-1; Cannabinoid receptor 1; CB-2; Cannabinoid receptor 2; CI; Combination Index; CXCR4; chemokine receptor type 4; DDS; Drug delivery syst
SDF-1/CXCR4 expression in head and neck cancer and outcome after postoperative radiochemotherapy
Keywords: SDF-1; CXCR4; Head and neck cancer; Prognostic; Biomarker; Postoperative radiochemotherapy;
Expression of C-X-C motif chemokine receptors 4 and 7 in salivary gland neoplasms
Keywords: CXCR4; CXCR7; Mucoepidermoid carcinoma; Adenoid cystic carcinoma; Pleomorphic adenoma; Polymorphous low-grade adenocarcinoma;
Transmembrane tumor necrosis factor-α promotes the recruitment of MDSCs to tumor tissue by upregulating CXCR4 expression via TNFR2
Keywords: Myeloid-derived suppressor cells (MDSC); Tumor; Chemotaxis; CXCR4; Transmembrane tumor necrosis factor-α; TNF receptor;
CXCR4 and CXCR7 play distinct roles in cardiac lineage specification and pharmacologic β-adrenergic response
Keywords: CXCR4; CXCR7; Cardiogenesis; hiPSC; Engineered tissue; hiPSC; human induced pluripotent stem cell; hiPSC-CM; human induced pluripotent stem cell-derived cardiomyocyte; hECT; human engineered cardiac tissue; GPCR; G-protein coupled receptor; SDF-1; stromal
Interaction of Zap70 and CXCR4 receptor at lamellipodia that determines the directionality during Jurkat T cells chemotaxis
Keywords: CXCR4; C-X-C chemokine receptor type 4; ECM; extracellular matrix; LFA-1; lymphocyte function-associated antigen 1; SDF-1; stromal cell-derived factor-1; TCR; T cell receptor; Zap70; zeta-associated protein-70; Zap70; CXCR4; SDF-1; Directionality; Cell ch
Clinicopathologic and prognostic significance of immunohistochemical expression of HIF-1α, CXCR4 and CA9 in colorectal carcinoma
Keywords: Colorectal carcinoma; Prognosis; Survival; HIF-1α; CA9; CXCR4;
Inhibitory effects of 3,3â²-diindolylmethane on epithelial-mesenchymal transition induced by endocrine disrupting chemicals in cellular and xenograft mouse models of breast cancer
Keywords: 3,3â²-diindolymethane; Triclosan; Bisphenol A; Epithelial-mesenchymal transition; Metastasis; Breast cancer cells; CXCR4;
Two distinct CXC chemokine receptors (CXCR3 and CXCR4) from the big-belly seahorse Hippocampus abdominalis: Molecular perspectives and immune defensive role upon pathogenic stress
Keywords: Seahorse; CXCR3; CXCR4; mRNA expression;
Hydroxysafflor yellow A promotes neovascularization and cardiac function recovery through HO-1/VEGF-A/SDF-1α cascade
Keywords: CAD; coronary artery disease; HSYA; hydroxysafflor yellow A; MI; myocardial infarction; EPCs; endothelial progenitor cells; HO-1; heme oxygenase-1; VEGF-A; vascular endothelial growth factor-A; SDF-1α; stromal cell-derived factor-1α; CXCR4; CXC chemokin
Research paperCXCR4 targeted dendrimer for anti-cancer drug delivery and breast cancer cell migration inhibition
Keywords: CXCR4; Targeted dendrimer; Breast cancer; BT-549-Luc; T47D;
Induced neural stem cells modulate microglia activation states via CXCL12/CXCR4 signaling
Keywords: Induced neural stem cell; Microglia; CXCR4; Closed head injury; Immunomodulation;
An update on small molecules targeting CXCR4 as starting points for the development of anti-cancer therapeutics
Keywords: CXCR4; Small molecules; Antagonists; Cancer;
Development of CXCR4 modulators by virtual HTS of a novel amide-sulfamide compound library
Keywords: CXCR4; Amide-sulfamide; Virtual HTS; Compound library building; Anti-inflammatory activity; QIYQWCBLYMCOSH-UHFFFAOYSA-N; HLTWLUMGQHBDCU-UHFFFAOYSA-N;
Novel anti-inflammatory agents targeting CXCR4: Design, synthesis, biological evaluation and preliminary pharmacokinetic study
Keywords: CXCR4; Amide-sulfamide; Inflammation; Structure-activity relationship; Pharmacokinetic study; KBWXKIUGGGUTOE-UHFFFAOYSA-N;
Molecular characterization of sdf1 and cxcr4 in the Mozambique tilapia, Oreochromis mossambicus
Keywords: Tilapia; Oreochromis; sdf; cxcr4; Reproduction; Cell migration;
Emerging roles of the CXCL12/CXCR4 axis in pancreatic cancer progression and therapy
Keywords: CAFs; cancer-associated fibroblasts; CIS; carcinoma in situ; CSCs; cancer stem cells; CXCL12; CXC ligand 12; CXCR4; CXC chemokine receptor 4; EMT; epithelial mesenchymal transition; HMGB1; high mobility group box 1; MDSCs; myeloid-derived suppressor cells
Astrocytic expression of the CXCL12 receptor, CXCR7/ACKR3 is a hallmark of the diseased, but not developing CNS
Keywords: CXCR7; CXCR4; Astrocytes; Glia limitans; MCAO; EAE; Spinal cord compression; Cerebral infarction; Alzheimer's disease;
Biomaterial-enabled delivery of SDF-1α at the ventral side of breast cancer cells reveals a crosstalk between cell receptors to promote the invasive phenotype
Keywords: Chemokines; SDF-1α/CXCL12; Breast cancer cells; Metastasis; Tumoral niche; Hyaluronan; Polyelectrolyte multilayer films; CXCR4; CD44;
Dipeptidyl peptidase 9 (DPP9) in human skin cells
Keywords: ADA; adenosine deaminase; APC; antigen-presenting cells; CXCR4; C-X-C chemokine receptor 4; DASH; dipeptidyl peptidase IV activity and/or structure homologues; DC; dendritic cells; DK-SFM; defined keratinocyte serum-free medium; DPP; dipeptidyl peptidase;
Combining 2D angiogenesis and 3D osteosarcoma microtissues to improve vascularization
Keywords: ARS; Alizarin red S; BrdU; 5-bromo-2-deoxy-uridine; BSPII; bone sialoprotein II; CXCR4; C-X-C chemokine receptor type 4; DAPI; 4â², 6-diamidino-2-phenylindole; GFP; green fluorescent protein; HDMS; hexamethyldisilazane; HUVEC; human umbilical vein endoth
O-linked-N-acetylglucosamine transferase is associated with metastatic spread of human papillomavirus E6 and E7 oncoproteins to the lungs of mice
Keywords: CXCR4; E6; E7; HPV-positive lung cancer; Metastasis; OGT;
The prenylflavonoid Icaritin enhances osteoblast proliferation and function by signal transducer and activator of transcription factor 3 (STAT-3) regulation of C-X-C chemokine receptor type 4 (CXCR4) expression
Keywords: Osteoblast; Icaritin; CXCR4; STAT-3; Anabolic therapeutic;
Association of Cytoplasmic CXCR4 With Loss of Epithelial Marker and Activation of ERK1/2 and AKT Signaling Pathways in Non-Small-Cell Lung Cancer
Keywords: AKT; CXCR4; E-cadherin; Epithelial-mesenchymal transition; ERK;
Waldenström Macroglobulinemia: Review of Pathogenesis and Management
Keywords: CXCR4; Lymphoid neoplasm; Lymphoplasmacytic lymphoma; Monoclonal immunoglobulin M; MYD88;
Design and computational support for the binding stability of a new CCR5/CXCR4 dual tropic inhibitor
Keywords: CCR5; CXCR4; HIV-1; Molecular dynamics; Ligand-protein interactions;
Constitutive activation of T cells by γ2-herpesviral GPCR through the interaction with cellular CXCR4
Keywords: γ-Herpesvirus; Viral G protein-coupled receptor; T cells; CXCR4;
SDF-1 and CXCR4 play an important role in adult SVZ lineage cell proliferation and differentiation
Keywords: Chemokine CXCL12; CXCR4; Neural stem cells; Lateral ventricles;
Aberrant methylation of RUNX3 is present in Aflatoxin B1-induced transformation of the L02R cell line
Keywords: TXNRD1; thioredoxin reductase 1; PCNA; proliferating cell nuclear antigen; CCNK; cyclin K; DIAPH3; diaphanous-related formin 3; RAB27B; ras-related protein rab-27B; HIST1H2BF; histone cluster 1, H2bf; HMG20B; high-mobility group 20B; JUNB; jun B proto-onc
Non-oxidizable HMGB1 induces cardiac fibroblasts migration via CXCR4 in a CXCL12-independent manner and worsens tissue remodeling after myocardial infarction
Keywords: Cardiac fibroblasts; Cardiac remodeling; Oxidation; Myocardial infarction; CXCR4;
Spatial encryption of G protein-coupled receptor signaling in endosomes; Mechanisms and applications
Keywords: AKT (PKB); protein kinase B; AP2; adaptor protein 2; APPL1; adaptor protein containing PH domain, PTB domain, and Leucine zipper motif; ARRDC; arresting domain containing; Î1AR; B2AR, beta-adrenergic receptor 1 or 2; CCP; clathrin coated pit; CXCR4; chem
Targeting SDF-1 in multiple myeloma tumor microenvironment
Keywords: SDF-1; CXCR4; Multiple myeloma; Microenvironment; Bone marrow;
Lack of specific alleles for the bovine chemokine (C-X-C) receptor type 4 (CXCR4) gene in West African cattle questions its role as a candidate for trypanotolerance
Keywords: CXCR4; Trypanotolerance; Bos taurus; Bos indicus; West Africa;
Increased stereotypy in conditional Cxcr4 knockout mice
Keywords: Stereotypy; Behavior; Mouse models; Parvalbumin interneurons; CXCR4; Chemokines;
CXCR4 overexpression correlates with poor prognosis in myasthenia gravis–associated thymoma
Keywords: Thymoma; Myasthenia gravis; CXCR4; Prognosis; Survival
Herbalog: A tool for target-based identification of herbal drug efficacy through molecular docking
Keywords: Herbalog; Natural product; Virtual screening; Molecular docking; FABP4 inhibitor; Andrographis paniculata; CXCR4; C-X-C chemokine receptor type 4; RMSD; Root-mean square deviation; FABP4; Fatty acid binding protein 4; 1; 8-ANS, 1-Anilinonaphthalene-8-sulf
Evidence of an interaction between TGF-β1 and the SDF-1/CXCR4/CXCR7 axis in human platelets
Keywords: CXCL12; CXCR4; CXCR7 protein, human; TGFbeta1; Platelets