miR-204-5p regulates cell proliferation and metastasis through inhibiting CXCR4 expression in OSCC
Keywords: miR-204-5p; OSCC; CXCR4
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Evidence of an interaction between TGF-β1 and the SDF-1/CXCR4/CXCR7 axis in human platelets
Keywords: CXCL12; CXCR4; CXCR7 protein, human; TGFbeta1; Platelets
Plerixafor improves the endothelial health balance. The effect of diabetes analysed by polychromatic flow cytometry
Keywords: Stem cells; Regeneration; Cardiovascular disease; Therapy; AAD; Actinomycin D; APC; Allophycocyanin; BM; bone marrow; CEC; circulating endothelial cell; CXCL12; Chemokine (C-X-C Motif) Ligand 12; CXCR4; Chemokine (C-X-C Motif) Receptor 4; EPC; endothelial
Clone-specific MYD88 L265P and CXCR4 mutation status can provide clinical utility in suspected Waldenström macroglobulinemia/lymphoplasmacytic lymphoma
Keywords: MYD88L256P; CXCR4; Waldenström's macroglobulinemia; Lymphoplasmacytic lymphoma; Flow cytometric cell sorting;
Predictive role of the overexpression for CXCR4, C-Met, and VEGF-C among breast cancer patients: A meta-analysis
Keywords: CXCR4; C-Met; VEGF-C; Overexpression; Breast cancer;
Branchial transcriptional responses of spotted scat, Scatophagus argus, to acute hypo-osmotic stress
Keywords: SW; salt water; FW; fresh water; SSH; suppression subtractive hybridization; arf1; ADP-ribosylation factor 1; creb3l4; cyclic AMP-responsive element-binding protein 3-like 4; evi5l; EVI5-like protein; fat2; protocadherin fat 2; tfr2; transferrin receptor
CXCR4 activation promotes differentiation of human embryonic stem cells to neural stem cells
Keywords: AP; alkaline phosphatase; BDNF; brain-derived neurotrophic factor; cAMP; cyclic adenosine monophosphate; CB1; cannabinoid receptor type 1; CB2; cannabinoid receptor type 2; CNS; central nervous system; CXCR4; CXC chemokine receptor type 4; CXCR7; CXC chem
CXCR4-targeted modular peptide carriers for efficient anti-VEGF siRNA delivery
Keywords: CXCR4; VEGF; siRNA; Glioblastoma; Endothelium; Cross-linking peptides;
Future therapeutic options for patients with Waldenström macroglobulinemia
Keywords: BTK; BCL2; CD38; CXCR4; MYD88; Waldenström;
CXCR4 signaling in health and disease
Keywords: Chemokine receptors; CXCR4; CXCL12; WHIM syndrome; Immunity; Signaling pathway
Systemic inflammation induces anxiety disorder through CXCL12/CXCR4 pathway
Keywords: Anxiety; Lipopolysaccharide; CXCL12; CXCR4; Glutamate; Neurotransmission;
Molecular mechanisms of LL-37-induced receptor activation: An overview
Keywords: AMP; antimicrobial peptide; APD; antimicrobial peptide database; IFN; interferon; DC; dendritic cell; NK-cells; natural killer cells; GPCR; G protein-coupled receptor; RTK; receptor tyrosine kinase; LGIC; ligand-gated ion channel; TLR; toll-like receptor;
Evidence for the involvement of the CXCL12 system in the adaptation of skeletal muscles to physical exercise
Keywords: CXCL12; CXCR4; Muscle fibers; C2C12 myotubes; Anabolic pathways; Catabolic pathways;
Micronome revealed miR-19a/b as key regulator of SOCS3 during cancer related inflammation of oral squamous cell carcinoma
Keywords: OSCC; Oral Squamous Cell Carcinoma; miRNA; MicroRNA; NGS; Next Generation Sequencing; STRING; Search Tool for Retrieval of Interacting Genes/Proteins; ACTREC; Advanced Centre for Treatment Research and Education in Cancer; HNOCDB; Head Neck Oral Cancer Da
Cloning and expression of Asian swamp eel (Monopterus albus) cxcr4 paralogues, and their modulation by pathogen infection
Keywords: Asian swamp eel; Cxcr4; Evolution; Expression
Minicircle microporation-based non-viral gene delivery improved the targeting of mesenchymal stem cells to an injury site
Keywords: Minicircle; Microporation; Mesenchymal stem cells; Non-viral gene delivery; Bioluminescence imaging; CXCR4
Role of chemokine pathways in hepatobiliary cancer
Keywords: Angiogenesis; Macrophages; CCR2; CCL2; CXCR4; CXCL12
Polyplex-mediated inhibition of chemokine receptor CXCR4 and chromatin-remodeling enzyme NCOA3 impedes pancreatic cancer progression and metastasis
Keywords: Polyplexes; siRNA delivery; Pancreatic cancer; Metastasis; CXCR4; NCOA3; Mucin; Tumor perfusion
The chronic lymphocytic leukemia microenvironment: Beyond the B-cell receptor
Keywords: Chronic lymphocytic leukemia; Microenvironment; Stroma; Nurse-like cell; Mesenchymal stromal cell; CXCR4; CXCL12; Chemokine; Wnt;
Discovery of non-peptide small molecular CXCR4 antagonists as anti-HIV agents: Recent advances and future opportunities
Keywords: AIDS; HIV-1; CXCR4; Small molecular; Entry inhibitors; Drug designHIV-1, human immunodeficiency virus-1; AIDS, acquired immunodeficiency syndrome; WHO, world health organization; HAART, highly active antiretroviral therapy; RT, reverse transcriptase; NNRT
Targeting CXCR4/SDF-1 axis by lipopolymer complexes of siRNA in acute myeloid leukemia
Keywords: Gene expression; CXCR4; SDF-1 (CXCL12); RNAi; SiRNA; Gene therapy; Acute myeloid leukemia (AML); THP-1; Bone marrow stromal cell attachment; Cell adhesion; Cell proliferation; Lipopolymer; Non-viral delivery; Co-culture; Drug delivery; Lipid;
Design, synthesis, and biological characterization of novel PEG-linked dimeric modulators for CXCR4
Keywords: CXCR4; PEG; Dimeric ligands;
Improved antitumor activity of epirubicin-loaded CXCR4-targeted polymeric nanoparticles in liver cancers
Keywords: Liver cancer; Epirubicin; CXCR4; Targeted nanoparticles; Biodistribution;
Edaravone promotes activation of resident cardiac stem cells by transplanted mesenchymal stem cells in a rat myocardial infarction model
Keywords: myocardial infarction; stem cell transplantation; edaravone; regeneration; ventricular function; bFGF; basic fibroblast growth factor; BMSC; bone marrow mesenchymal stem cell; BrdU; 5-bromo-2-deoxyuridine; CD; cluster of differentiation; CSC; cardiac stem
Microvesicles enhance the mobility of human diabetic adipose tissue-derived mesenchymal stem cells in vitro and improve wound healing in vivo
Keywords: Microvesicles; Mesenchymal stem cells; Wound healing; Flap mouse model; Diabetes; SDF-1; stromal cell-derived factor 1; CXCR4; C-X-C chemokine receptor type 4; CXCR7; C-X-C chemokine receptor type 7; CCL2; chemokine (CeC motif) ligand 2; ANGPTL4; angiopoi
CXCR4 signaling is controlled by immobilization at the plasma membrane
Keywords: CXCR4; Single molecule; Signaling; Endocytosis;
Characterization of the interaction between the dopamine D4 receptor, KLHL12 and β-arrestins
Keywords: GPCR; β-arrestin; KLHL12; ubiquitination; dopamine D4 receptor; β2AR; β2-adrenergic receptor; ADHD; attention deficit hyperactivity disorder; BTB; bric à brac 1, tramtrack, and broad-complex; co-IP; co-immunoprecipitation; CXCR4; C-X-C chemokine recep
Boning up on DPP4, DPP4 substrates, and DPP4-adipokine interactions: Logical reasoning and known facts about bone related effects of DPP4 inhibitors
Keywords: ALP; alkaline phosphatase,; APN(R); adiponectin (receptor); BMD; bone mineral density; Coll1; collagen type 1; CXCR4; C-X-C chemokine receptor 4; DPP4; dipeptidyl peptidase 4 (CD26: cluster of differentiation 26); GLP-1/2; glucagon-like peptide 1/2; GIP;
Toll-like receptor-3 mediates HIV-1 transactivation via NFκB and JNK pathways and histone acetylation, but prolonged activation suppresses Tat and HIV-1 replication
Keywords: TLR3; HIV; Viral transactivation; LTR; NFκB; JNK; STAT1; Histone acetylation; Epigenetics; Human monocyte-derived macrophages; TZM-bl; U38 cells; AP-1; activator protein-1; B2M; beta-2-microglobulin; BCA; bicinchoninic acid; CAT; chloramphenicol acetyltr
Pre-treatment of allogeneic bone marrow recipients with the CXCR4 antagonist AMD3100 transiently enhances hematopoietic chimerism without promoting donor-specific skin allograft tolerance
Keywords: AMD3100; CXCR4; Bone marrow mobilization; Mixed chimerism; Tolerance
CXCL12 and CXCR4, but not CXCR7, are primarily expressed by the stroma in head and neck squamous cell carcinoma
Keywords: CXCL12; CXCR4; CXCR7; head and neck cancer; laser microdissection; oral cancer; SDF-1; stroma;
Efficient one-pot synthesis of CXCL14 and its derivative using an N-sulfanylethylanilide peptide as a peptide thioester equivalent and their biological evaluation
Keywords: Chemokine; CXCL14; CXCR4; CXCL12; Native Chemical Ligation (NCL);
A SDF1 genetic variant confers resistance to HIV-1 infection in intravenous drug users in China
Keywords: HIV-1; Genetic variants; SDF1; CCR5; CXCR4; Intravenous drug user;
Effect of CXCR4 pretreated with ultrasound-exposed microbubbles on accelerating homing of bone marrow mesenchymal stem cells to ischemic myocardium in AMI rats
Keywords: Ultrasound-exposed microbubbles; Bone marrow mesenchymal stem cells; CXCR4; Calcium ion
Targeting cancer stem cells in solid tumors by vitamin D
Keywords: CSC; Cancer stem cell; 1α,25(OH)2D3; 1α,25-dihydroxyvitamin D3; EpCAM; Epithelial cell adhesion molecule; PROM1; Prominin 1; CXCR4; C-X-C chemokine receptor type 4; SDF1; Stromal cell-derived factor 1; ALDH-1; Aldehyde dehydrogenease-1; EMT; Epithelial-
MicroRNA in prostate cancer
Keywords: DGCR8; Digeorge syndrome chromosomal region 8; CCNDs; cyclin Ds; CDK4; cyclin-dependent kinase 4; CDK6; cyclin-dependent kinase 6; E2F; E2 transcription factor; E2F2; E2 transcription factor 2; IGF1R; insulin-like growth factor 1 receptor; ELK1; ELK1 memb
hCG stimulates angiogenic signals in lymphatic endothelial and circulating angiogenic cells
Keywords: hCG; human chorionic gonadotropin; HIF-1α; hypoxia inducible factor-1α; CXCL12; C-X-C motif chemokine 12; CXCR4; C-X-C chemokine receptor type 4; CAC; circulating angiogenic cells; LH; luteinizing hormone; LEC; lymphatic endothelial cells; UTM; uterine
LFC131 peptide-conjugated polymeric nanoparticles for the effective delivery of docetaxel in CXCR4 overexpressed lung cancer cells
Keywords: CXCR4; LFC131 peptide; Lung cancers; Polymeric nanoparticles; Targeted approach; Docetaxel;
Role of lipid microdomains in TLR-mediated signalling
Keywords: ABCA1/G1; ATP-binding cassette, sub-family A/G, member 1; AP-1; activator protein 1; CARC; inverted “CRAC” domain; CD 14/36/55; cluster of differentiation 14/36/55; CRAC; cholesterol recognition amino-acid consensus sequence; CXCR4; C-X-C chemokine re
Mapping the CXCR4 receptor on breast cancer cells
Keywords: Atomic force microscopy (AFM); CXCR4; Breast cancer; Young's modulus; Adhesion; Drug delivery
Targeted delivery of CXCR4-siRNA by scFv for HER2+ breast cancer therapy
Keywords: siRNA delivery; Breast cancer therapy; CXCR4; Single-chain antibody fragment;
Infiltration of plasma rich in growth factors enhances in vivo angiogenesis and improves reperfusion and tissue remodeling after severe hind limb ischemia
Keywords: BDNF; brain-derived neurotrophic factor; BMP; bone morphogenetic proteins; CXCR4; chemokine receptor type-4; ECs; endothelial cells; EGF; epidermal growth factor; FGF; fibroblast growth factor; GF; growth factors; HGF; hepatocyte growth factor; hSkMbs; hu
Applications of stripe assay in the study of CXCL12-mediated neural progenitor cell migration and polarization
Keywords: PDMS; Stripe assay; Polarization; Migration; CXCL12; CXCR4;
Stoichiometric parameters of HIV-1 entry
Keywords: HIV-2; gp120; Env; Entry; Relative infectivity; CD4; CCR5; CXCR4;
CXCR4: A Potential Marker for Inflammatory Activity in Abdominal Aortic Aneurysm Wall
Keywords: Abdominal aortic aneurysm; CXCR4; CXCL12; Gene expression; Inflammatory processes;
Cyclin C interacts with steroid receptor coactivator 2 and upregulates cell cycle genes in MCF-7 cells
Keywords: 6His; hexahistidine tag; aa; amino acids; Bcl-2; apoptosis regulator B-cell CLL/lymphoma 2; cAMP; cyclic adenosine monophosphate; CCNC; cyclin C; CCPG1; cell cycle progression protein 1; CDK6; cyclin-dependent kinase 6; cDNA; coding DNA; CXCR4; chemokine
Hormone receptor-independent CXCL10 production is associated with the regulation of cellular factors linked to breast cancer progression and metastasis
Keywords: Circulating tumor cells (CTCs); CXCL10; CXCR3; CXCR4; Survivin; MMP-1; Metastasis; Breast cancer;
CXCL12 and CXCR4 as predictive biomarkers of glioma recurrence pattern after total resection
Keywords: Gliomas; CXCR4; CXCL12; Recurrence patternGliome; CXXR4; CXCL12; Récidive
Caloric restriction and the adipokine leptin alter the SDF-1 signaling axis in bone marrow and in bone marrow derived mesenchymal stem cells
Keywords: Aging; Osteoporosis; CXCR4; CXCR7; Nutrient signaling; Bone formation
Molecular Imaging of the Chemokine Receptor CXCR4 After Acute Myocardial Infarction
Keywords: CXCR4; inflammation; myocardial infarction; positron emission tomography; ACE; angiotensin-converting enzyme; AMI; acute myocardial infarction; CMR; cardiac magnetic resonance; 18F-FDG; 18F-fluorodeoxyglucose; 68Ga; gallium-68; I/R; infarct to remote rati