دانلود مقالات ISI درباره کییناز وابسته به سیکلین + ترجمه فارسی

Multiple pathways of SIRT6 at the crossroads in the control of longevity, cancer, and cardiovascular diseases

Keywords: کییناز وابسته به سیکلین; ALP; alkaline phosphatase; AMPK; AMP-activated protein kinase; Ang II; angiotensin II; BER; base excision repair; cAMP; cyclic adenosine monophosphate; CDK; cyclin-dependent kinase; CHIP; carboxyl terminus of Hsp70-interacting protein; CLL; chronic lympho

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

5-Bromoindirubin 3′-(O-oxiran-2-ylmethyl)oxime: A long-acting anticancer agent and a suicide inhibitor for epoxide hydrolase

Keywords: کییناز وابسته به سیکلین; ATP; adenosine 5′-triphosphate; C1; methylene; C2; ethylene; C3; propylene; CDK; cyclin-dependent kinase; Cys; cysteine residue; DMF; N,N-dimethylformamide; DMSO; dimethyl sulfoxide; EI; electron impact; Epox/5-Br-Ind; 5-bromoindirubin 3′-(O-oxiran-2-

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Combined Inhibition of CDK4/6 and PI3K/AKT/mTOR Pathways Induces a Synergistic Anti-Tumor Effect in Malignant Pleural Mesothelioma Cells

Keywords: کییناز وابسته به سیکلین; MPM; Malignant Pleural Mesothelioma; BAP1; BRCA1 Associated Protein 1; CDK; Cyclin-dependent kinase; RB; Retinoblastoma Protein; SA-β-GAL; Senescence Associated β-Galactosidase;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

ReviewCaloric restriction - A promising anti-cancer approach: From molecular mechanisms to clinical trials

Keywords: کییناز وابسته به سیکلین; Acetyl-CoA/CoA; acetyl-coenzyme A/Coenzyme A ratio; AMPK; AMP-dependent kinase; APL; autophagolysosome; ATG; autophagy-related gene; ATP/ADP; adenosine triphosphate/adenosine diphosphate ratio; CDK; cyclin-dependent kinase; CR; caloric restriction; CRM; c

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Studies of CDK 8/19 inhibitors: Discovery of novel and selective CDK8/19 dual inhibitors and elimination of their CYP3A4 time-dependent inhibition potential

Keywords: کییناز وابسته به سیکلین; ADME; absorption, distribution, metabolism, and excretion; AML; acute myelogenous leukemia; AUC; area under the blood concentration time curve; b.i.d.; twice a day; CDK; Cyclin-dependent kinase; CLtotal; clearance; Cmax; maximum drug concentration; CRC; c

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling

Keywords: کییناز وابسته به سیکلین; GPCR; G protein-coupled receptor; GRK; G protein-coupled receptor kinases; SA-β-Gal; senescence-associated-β-galactosidase; FACS; fluorescence-activated cell sorting; CCK-8; cell counting kit-8; CDK; cyclin-dependent kinase; CKI; cyclin-dependent kinase

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

Upregulation of microRNA-574-3p in a human gastric cancer cell line AGS by TGF-β1

Keywords: کییناز وابسته به سیکلین; miRNA; microRNA; TGF-β1; transforming growth factor-β1; Smad; mammalian homologue of Drosophila Mad and C. elegans Sma; mRISC; miRNA-induced silencing complex; EMT; epithelial-mesenchymal transformation; BSA; bovine serum albumin; NC; negative control;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

Skin-Specific Deletion of Mis18α Impedes Proliferation and Stratification of Epidermal Keratinocytes

Keywords: کییناز وابسته به سیکلین; CDK; cyclin-dependent kinase; E; embryonic day; K; keratin; P; postnatal day; PBS; phosphate buffered saline;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

Roscovitine attenuates intimal hyperplasia via inhibiting NF-κB and STAT3 activation induced by TNF-α in vascular smooth muscle cells

Keywords: کییناز وابسته به سیکلین; VSMCs; vascular smooth muscle cells; TNF-α; tumor necrosis factor α; MAPKs; mitogen-activated protein kinases; NF-κB; nuclear factor-kappa B; JAK-STAT; Janus kinase-signal transducer and activator of transcription; IL-1β; interleukin-lβ; MCP-1; monoc

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Trichodermin induces c-Jun N-terminal kinase-dependent apoptosis caused by mitotic arrest and DNA damage in human p53-mutated pancreatic cancer cells and xenografts

Keywords: کییناز وابسته به سیکلین; Pancreatic cancer; Mitotic arrest; DNA damage; Apoptosis; c-Jun N-terminal kinase; Trichodermin; Bcl-2; B-cell lymphoma 2; Bcl-xL; B-cell lymphoma extra long; CDK; cyclin-dependent kinase; Cdc; cell division cycle; DSBs; double-strand breaks; DUSP1; dual

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

Identification, expression pattern and functional characterization of As-kip2 in diapause embryo restarting process of Artemia sinica

Keywords: کییناز وابسته به سیکلین; As-kip2; p57Kip2 mRNA from Artemia sinica; As-KIP2; p57Kip2 protein from Artemia sinica; As-CARP-1; cell cycle and apoptosis regulator 1 protein from Artemia sinica; As-SODD; silencer of death domain protein from Artemia sinica; CDK; cyclin-dependent kina

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2017 سفارش ترجمه

Linking deregulation of non-coding RNA to the core pathophysiology of Alzheimer's disease: An integrative review

Keywords: کییناز وابسته به سیکلین; Aβ42; β-amyloid42; ABCA1; ATP-Binding Cassette Transporter A1; AD; Alzheimers disease; ADAM; AD-related disintegrin and metalloprotease; AICD; APP- intracellular domain; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ApoE; ApolipoproteinE;

دانلود رایگان متن کامل مقاله ISI 175 صفحه سال انتشار : 2017 سفارش ترجمه

Treatment Rationale and Study Design for the JUNIPER Study: A Randomized Phase III Study of Abemaciclib With Best Supportive Care Versus Erlotinib With Best Supportive Care in Patients With Stage IV Non-Small-Cell Lung Cancer With a Detectable KRAS Mutati

Keywords: کییناز وابسته به سیکلین; Biomarkers; CDK4; CDK6; Cyclin-dependent kinase; LY2835219;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

MiR-106a: Promising biomarker for cancer

Keywords: کییناز وابسته به سیکلین; MiRNAs; micro RNAs; FASTK; Fas-activated serine/threonine kinase; MAPK; mitogen-activated protein kinase; NSCLC; non-small cell lung cancer; P-gp; P-glyco-protein; MDR; multidrug resistance; ABCA1; adenosine triphosphatase-binding cassette A1; TIMP2; tiss

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Endocrine therapy for hormone treatment-naïve advanced breast cancer

Keywords: کییناز وابسته به سیکلین; Advanced breast cancer; Metastatic breast cancer; Endocrine therapy; Endocrine therapy-naïve; CBR; clinical benefit rate; CDK; cyclin-dependent kinase; CI; confidence interval; ER; estrogen receptor; HER; human epidermal growth factor receptor; HR; hazar

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

c-Rel in Epidermal Homeostasis: A Spotlight on c-Rel in Cell Cycle Regulation

Keywords: کییناز وابسته به سیکلین; CDK; cyclin-dependent kinase; IKK; inhibitor of κB kinase; MCC; mitotic checkpoint complex; SAC; spindle assembly checkpoint; TNF; tumor necrosis factor;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Curcumin-cyclodextrin complexes enhanced the anti-cancer effects of curcumin

Keywords: کییناز وابسته به سیکلین; CD; β-cyclodextrin; CD15; curcumin-cyclodextrin complexes; CDK; cyclin-dependent kinase; CUR; curcumin; FACS; fluorescence activated cell sorter; FTIR; Fourier transform infrared; IC50; 50% inhibitory concentration; MTT; 3-(4,5-Dimethyl-thiagol-2yl)- 2,5

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

d-3-Deoxy-dioctanoylphosphatidylinositol induces cytotoxicity in human MCF-7 breast cancer cells via a mechanism that involves downregulation of the D-type cyclin-retinoblastoma pathway

Keywords: کییناز وابسته به سیکلین; BrdU; 5-bromo-2′-deoxyuridine; CDK; cyclin-dependent kinase; CMC; critical micelle concentration; d-3-deoxy-diC8PI; d-3-deoxy-dioctanoylphosphatidylinositol; l-3,5-dideoxy-diC8PI; l-3,5-dideoxy-dioctanoylphosphatidylinositol; d-diC8PIP3; d-dioctanoyl-ph

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Down-regulation of BNIP3 by olomoucine, a CDK inhibitor, reduces LPS- and NO-induced cell death in BV2 microglial cells

Keywords: کییناز وابسته به سیکلین; Aβ; amyloid β; BH3; Bcl−2 homology domain 3; BNIP3; Bcl-2/adenovirus E1B 19−kDa-interacting protein 3; CNS; central nervous system; cPTIO; carboxy-PTIO; CDK; cyclin-dependent kinase; DMEM; Dulbecco's modified Eagle medium; HD; Huntington's disea

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Retinoid N-(1H-benzo[d]imidazol-2-yl)-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2-carboxamide induces p21-dependent senescence in breast cancer cells

Keywords: کییناز وابسته به سیکلین; ATRA; all-trans-retinoic acid; CDK; cyclin-dependent kinase; ER; estrogen receptor; RA; retinoic acid; OIS; oncogene-induced senescence; PICS; PTEN-loss induced cellular senescence; SRB; Sulforhodamine B; SABG; senescence-associated β-galactosidase; siRN

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Original articleMultiple primary melanomas (MPMs) and criteria for genetic assessment: MultiMEL, a multicenter study of the Italian Melanoma Intergroup

Keywords: کییناز وابسته به سیکلین; cyclin-dependent kinase; cyclin-dependent kinase inhibitor 2A; family history; genetic assessment; melanoma; microphthalmia-associated transcription factor; mutation; pancreatic cancer; CDK; cyclin-dependent kinase; CDKN2A; cyclin-dependent kinase inhibit

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

GSK-3 inhibition overcomes chemoresistance in human breast cancer

Keywords: کییناز وابسته به سیکلین; Breast cancer; GSK-3; Chemoresistance; 9-ING-41; Drug development; ADMET; absorption, distribution, metabolism, excretion, toxicity; PK; pharmacokinetic; CDK; cyclin-dependent kinase; PKA; protein kinase A; Akt; protein kinase B; PKC; protein kinase C; GL

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Nephrotoxicity of epigenetic inhibitors used for the treatment of cancer

Keywords: کییناز وابسته به سیکلین; Epigenetic inhibitors; Prostate cancer; Kidney cells; Nephrotoxicity; 5-Aza; 5-aza-2ʹ-deoxycytidine; CBZ; carbamazapine; CDK; cyclin-dependent kinase; CDKN1a; cyclin-dependent kinase inhibitor 1a; CFZ; carfilzomib; ChIP; chromatin immunoprecipitation; DM

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Mitotic-dependent phosphorylation of leukemia-associated RhoGEF (LARG) by Cdk1

Keywords: کییناز وابسته به سیکلین; LARG; leukemia-associated Rho guanine nucleotide exchange factor; GTP; guanine-nucleotide triphosphate; GEF; guanine-nucleotide exchange factor; RhoGEF; Rho guanine-nucleotide exchange factor; Cdk1; cyclin-dependent kinase; pNull; phosphonull; pMim; phosp

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

PHOX2A and PHOX2B are differentially regulated during retinoic acid-driven differentiation of SK-N-BE(2)C neuroblastoma cell line

Keywords: کییناز وابسته به سیکلین; α3 nAChR; alpha 3 nicotinic Acetylcholine Receptor; ATRA; all-trans Retinoic Acid; BMP-2; Bone morphogenetic protein-2; CCHS; Congenital Central Hypoventilation Syndrome; Cdk; cyclin-dependent kinase; ChIP; chromatin immunoprecipitation; CKI; Cdk inhibit

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Research ArticleLoss of Gsα impairs liver regeneration through a defect in the crosstalk between cAMP and growth factor signaling

Keywords: کییناز وابسته به سیکلین; cAMP; cyclic adenosine monophosphate; CCl4; carbon tetrachloride; CDK; cyclin-dependent kinase; CREB; cAMP-responsive element-binding protein; Erk; extracellular signal-regulated kinase; GPCR; G-protein-coupled receptor; Gsα; the stimulatory G protein α

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Pro-Proliferative Function of Mitochondrial Sirtuin Deacetylase SIRT3 in Human Melanoma

Keywords: کییناز وابسته به سیکلین; cdk; cyclin-dependent kinase; SA-β-Gal; senescence-associated beta-galactosidase; SAHF; senescence-associated heterochromatin foci; shNS; nonspecific shRNA; shRNA; short hairpin RNA; SIRTs; sirtuins; TMAs; tissue microarrays;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

In vivo anti-tumor activity of the PARP inhibitor niraparib in homologous recombination deficient and proficient ovarian carcinoma

Keywords: کییناز وابسته به سیکلین; BRCA1/2; BRCA1 or BRCA2; CDK; cyclin-dependent kinase; FBS; heat-inactivated fetal bovine serum; HGSOC; high-grade serous ovarian carcinoma; HR; homologous recombination; IP; intraperitoneal; pADPr; poly(ADP-ribose) polymer; PARP; poly(ADP-ribose) polymer

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Original ArticleMelanocytes/MelanomaThe Long Noncoding RNA SPRIGHTLY Regulates Cell Proliferation in Primary Human Melanocytes

Keywords: کییناز وابسته به سیکلین; CDK; cyclin-dependent kinase; DPPIV; dipeptidyl peptidase-IV; ERK; extracellular signal-regulated kinase; lncRNA; long noncoding RNA; MAPK; mitogen-activated protein kinase; MCM; minichromosome maintenance; siRNA; small interfering RNA;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

5-Substituted 3-chlorokenpaullone derivatives are potent inhibitors of Trypanosoma brucei bloodstream forms

Keywords: کییناز وابسته به سیکلین; ACN; acetonitrile; CDK; cyclin-dependent kinase; CLK; cdc2-like kinase; CK; casein kinase; DIPEA; diisopropylethylamine; DMEM; Dulbecco's modified Eagle's medium; DMF; N,N-dimethylformamide; DMSO; dimethyl sulfoxide; DYRK1A; dual specificity tyrosine

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Chikusetsusaponin IVa methyl ester induces G1 cell cycle arrest, triggers apoptosis and inhibits migration and invasion in ovarian cancer cells

Keywords: کییناز وابسته به سیکلین; Panacis Japonici Rhizoma; Chikusetsusaponin IVa methyl ester; Ovarian cancer; Cell cycle arrest; Apoptosis; Metastasis; Bcl-2; B-cell lymphoma 2; CC; column chromatography; CDK; cyclin-dependent kinase; DMEM; Dulbecco's modified Eagle's medium; DMSO; dime

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Regulations on growth and development in tomato cotyledon, flower and fruit via destruction of miR396 with short tandem target mimic

Keywords: کییناز وابسته به سیکلین; AOI; area of interest; BK; breaker; CDK; cyclin-dependent kinase; DPA; days post-anthesis; DPS; days post-sowing; GRF; growth-regulating factor; MC; MACROCALYX; MG; mature green; miRNA; microRNA; MT; Micro-Tom; NCBI; National Center for Biotechnology Info

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Original PaperA Transcriptome-based Perspective of Cell Cycle Regulation in Dinoflagellates

Keywords: کییناز وابسته به سیکلین; Dinoflagellate; cell cycle; cyclin; cyclin-dependent kinase; S phase; M phase.;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Structural Conservation and E2F Binding Specificity within the Retinoblastoma Pocket Protein Family

Keywords: کییناز وابسته به سیکلین; Rb; retinoblastoma; Cdk; Cyclin-dependent kinase; E2FTD; E2F transactivation domain; p107/p130; p107 or p130; RbN; Rb containing a structured N-terminal domain; RbC; Rb containing an intrinsically disordered C-terminal domain; RbPL; Rb containing a ~ 60

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Long non-coding RNA UCA1 promotes cisplatin/gemcitabine resistance through CREB modulating miR-196a-5p in bladder cancer cells

Keywords: کییناز وابسته به سیکلین; UCA1; CREB; miR-196a-5p; Drug resistance; Bladder cancer; CDK; cyclin-dependent kinase; CREB; cAMP response element-binding protein; DAB; diaminobenzidine; 5-FU; 5-fluorouracil; IHC; immunohistochemistry; lncRNA; long non-coding RNA; miRNA; micro RNA; NC;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

The anaphase-promoting complex works together with the SCF complex for proteolysis of the S-phase cyclin Clb6 during the transition from G1 to S phase

Keywords: کییناز وابسته به سیکلین; Anaphase-promoting complex/cyclosome; Cdh1; Cyclin-dependent kinase; G1-S phase transition;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Oncogenic KRAS signaling and YAP1/β-catenin: Similar cell cycle control in tumor initiation

Keywords: کییناز وابسته به سیکلین; YAP1; Yes; MAPK; mitogen-activated protein kinase; ERK; extracellular signal-regulated kinase; eIF4E; eukaryotic translation initiation factor 4E; PI3K; phosphatidylinositide-3-kinase; WNT; Wingless-type mouse mammary tumor virus integration site family m

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2016 سفارش ترجمه

Rapamycin requires AMPK activity and p27 expression for promoting autophagy-dependent Tsc2-null cell survival

Keywords: کییناز وابسته به سیکلین; AMPK; 5′ AMP-activated protein kinase; Atg13; autophagy-related protein 13; CDK; cyclin-dependent kinase; DAPI; 4′,6-diamidino-2-phenylindole; DMEM; Dulbecco's modified eagle's medium; DMSO; dimethyl sulfoxide; FDA; US Food and Drug Administration; GF

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2016 سفارش ترجمه

Studying mechanisms of cAMP and cyclic nucleotide phosphodiesterase signaling in Leydig cell function with phosphoproteomics

Keywords: کییناز وابسته به سیکلین; AC; adenylyl cyclase; ACTH; adrenocorticotropic hormone; AKAP; A-kinase anchor protein; AMP; 5′ adenosine monophosphate; AMPK; AMP-activated protein kinase; Arfgap1; ADP-ribosylation factor GTPase-activating protein 1; Arhgef2; Rho guanine nucleotide ex

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2016 سفارش ترجمه

Skp1: Implications in cancer and SCF-oriented anti-cancer drug discovery

Keywords: کییناز وابسته به سیکلین; Arf6; ADP-ribosylation factor 6; BIMEL; extra-long isoform of BIM; β-TRCP; β-transducin repeat-containing protein; CDCA3; cell division cycle associated 3; CDK; cyclin-dependent kinase; CENP-E; centrosome-associated protein E; Cks1; cyclin-dependent pro

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

Schizophrenia susceptibility gene product dysbindin-1 regulates the homeostasis of cyclin D1

Keywords: کییناز وابسته به سیکلین; BLOC-1; Biogenesis of lysosome-related organelles complex 1; CDK; Cyclin-dependent kinase; DPC; dystrophin-associated glycoprotein complex; DMEM; Dulbecco's modified Eagle's medium; GFP; Green fluorescent protein; FBS; Fetal bovine serum; MBP; Maltose bin

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2016 سفارش ترجمه

Bioluminescent kinase strips: A novel approach to targeted and flexible kinase inhibitor profiling

Keywords: کییناز وابسته به سیکلین; Kinase profiling; Bioluminescence; ADP detection; Selectivity profiles; Kinase assay; Kinase inhibitor; PTM; post-translational modification; FDA; U.S. Food and Drug Administration; BSA; bovine serum albumin; DMSO; dimethyl sulfoxide; TK; tyrosine kinase

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2016 سفارش ترجمه

Gleditsia species: An ethnomedical, phytochemical and pharmacological review

Keywords: کییناز وابسته به سیکلین; AFGS; the ethanol extract from the anomalous fruits of Gleditsia sinensis Lam.; ALI; acute lung injury; AML; acute myelogenous leukemia; AP-1; activator protein-1; ARDS; acute respiratory distress syndrome; bFGF; basic fibroblast growth factor; CDK; cycli

دانلود رایگان متن کامل مقاله ISI 62 صفحه سال انتشار : 2016 سفارش ترجمه

Cancer TARGETases: DSB repair as a pharmacological target

Keywords: کییناز وابسته به سیکلین; DSB repair; Genome instability; Cancer; Kinases; Helicases; Nucleases; ALT; alternative telomere lengthening; AML; acute myeloid leukemia; A-T; ataxia-telangiectasia; ATM; ataxia-telangiectasia mutated; ATP; adenosine triphosphate; ATR; ataxia-tel

دانلود رایگان متن کامل مقاله ISI 110 صفحه سال انتشار : 2016 سفارش ترجمه

2,6,9-Trisubstituted purines as CRK3 kinase inhibitors with antileishmanial activity in vitro

Keywords: کییناز وابسته به سیکلین; CRK, Cdc2-related protein kinasePurine; Inhibitor; Cyclin-dependent kinase; Leishmania

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2015 سفارش ترجمه

Rapamycin-induced G1 cell cycle arrest employs both TGF-β and Rb pathways

Keywords: کییناز وابسته به سیکلین; mTOR; Rapamycin; Rb; TGF-β; eIF4E; 4E-BP1; eIF4E-binding protein-1; CDK; cyclin-dependent kinase; eIF4E; eukaryotic initiation factor 4E; mTOR; mammalian target of rapamycin; mTORC1; mTOR complex 1; S6K; S6 kinase; TGF-β; transforming growth factor-β;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Lovastatin suppresses the aberrant tau phosphorylation from FTDP-17 mutation and okadaic acid-induction in rat primary neurons

Keywords: کییناز وابسته به سیکلین; AAV; adeno-associated virus; ACAT; acyl-CoA:cholesterol acyltransferase; AD; Alzheimer's disease; CDK; cyclin-dependent kinase; EDTA; ethylenediaminetetraacetic acid; EGTA; ethylene glycol tetraacetic acid; FTDP-17; frontotemporal dementia and Parkinson

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Design and synthesis of a potent inhibitor of class 1 DYRK kinases as a suppressor of adipogenesis

Keywords: کییناز وابسته به سیکلین; CHK; CSK (C-terminal Src kinase)-homologous kinase; CLK; Cdc2-like kinase; HIPK; homeodomain-interacting protein kinase; PIM; proviral integration of moloney murine leukemia virus; PKD; protein kinase D; FLT; Fms-like tyrosine kinase; CDK; cyclin-dependen

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Cell Cycle Regulation of Smooth Muscle Cells-Searching for Inhibitors of Neointima Formation: Is Combretastatin A4 an Alternative to Sirolimus and Paclitaxel?

Keywords: کییناز وابسته به سیکلین; CA4; combretastatin A4; CDK; cyclin-dependent kinase; CI; confidence interval; mTOR; mammalian target of rapamycin; PPARγ; peroxisome proliferator activated receptor γ; SMC; smooth muscle cell;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Research ReportSynergistic anti-tumor actions of luteolin and silibinin prevented cell migration and invasion and induced apoptosis in glioblastoma SNB19 cells and glioblastoma stem cells

Keywords: کییناز وابسته به سیکلین; CDK; cyclin-dependent kinase; DMSO; dimethyl sulfoxide; ECL; enhanced chemiluminescence; FBS; fetal bovine serum; GSC; glioblastoma stem cells; ICAD; inhibitor of caspase activated DNase; IgG; immunoglobulin G; iNOS; inducible nitric oxide synthase; LUT;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه