Keywords: Aldosterone; Chimera; CYP11B1; CYP11B2; KCNJ5; ATP1A1; ATP2B3; CACNA1D; CACNA1H; CTNNB1;
مقالات ISI (ترجمه نشده)
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Keywords: Di(2-ethylhexyl) phthalate (DEHP); Mono(2-ethylhexyl) phthalate (MEHP); Adrenal androgen; Glucocorticoid; Prenatal exposure; Fetal blood; CI; confidence interval; CYP11A1; cytochrome P450 family 11 subfamily A member 1; CYP11B1; cytochrome P450 family 11
Keywords: ACTH; adrenocorticotropic hormone; cAMP/PKA; cAMP-dependent protein kinase A; CD; cluster of differentiation; CRH; corticotrophin releasing hormone; CYP11A1 or P450scc; cytochrome P450 side-chain cleavage enzyme; CYP11B1; 11β-hydroxylase type 1; CYP11B2;
Prevalence, clinical characteristics and long-term outcomes of classical 11 β-hydroxylase deficiency (11BOHD) in Turkish population and novel mutations in CYP11B1 gene
Keywords: Congenital adrenal hyperplasia; 11β-hydroxylase deficiency; CYP11B1; Gene; Genotype-Phenotype; Novel CYP11B1 mutation;
Catalytic modulation of human cytochromes P450 17A1 and P450 11B2 by phospholipid
Keywords: CYP17A1; cytochrome P450 17A1; CYP11B1; cytochrome P450 11B1; CYP11B2; cytochrome P450 11B2; POR; cytochrome P450-oxidoreductase; 12:0 PC (DLPC); 1,2-dioleoyl-sn-glycero-3-phosphocholine; 14:0 PC; 1,2-dimyristoyl-sn-glycero-3-phosphocholine; 16:0 PC; 1,2-
4-Anilino-pyrimidine, novel aldosterone synthase (CYP11B2) inhibitors bearing pyrimidine structures
Keywords: Aldosterone; CYP11B2; CYP11B1; Aldosterone synthase inhibitor; Amino-pyrimidine;
Novel and prevalent CYP11B1 gene mutations in Turkish patients with 11-β hydroxylase deficiency
Keywords: Congenital adrenal hyperplasia; CYP11B1; 11beta-hydroxylase deficiency; CYP11B1 novel mutations;
A high rate of novel CYP11B1 mutations in Saudi Arabia
Keywords: Congenital adrenal hyperplasia; CYP11B1; Mutations; Ambiguous genitalia;
Intratumoral heterogeneity of steroidogenesis in aldosterone-producing adenoma revealed by intensive double- and triple-immunostaining for CYP11B2/B1 and CYP17
Keywords: Aldosterone-producing adenoma; CYP11B1; CYP11B2; CYP17; Double-immunostaining; Triple-immunostaining;
Expression of steroidogenic enzymes and their transcription factors in cortisol-producing adrenocortical adenomas: immunohistochemical analysis and quantitative real-time polymerase chain reaction studies
Keywords: Cortisol-producing adrenocortical adenoma; HSD3B1; HSD3B2; CYP11B1; CYP11B2;
Phenotypic, metabolic, and molecular genetic characterization of six patients with congenital adrenal hyperplasia caused by novel mutations in the CYP11B1 gene
Keywords: 11β-hydroxylase; Congenital adrenal hyperplasia; CYP11B1; CYP11B1 mutant; Steroid hormone
Identification of seven novel CYP11B1 gene mutations in Chinese patients with 11β-hydroxylase deficiency
Keywords: Congenital adrenal hyperplasia; 11-Beta-hydroxylase deficiency; CYP11B1; Mutation
Osthole, a coumadin analog from Cnidium monnieri (L.) Cusson, stimulates corticosterone secretion by increasing steroidogenic enzyme expression in mouse Y1 adrenocortical tumor cells
Keywords: Osthole; Corticosterone; StAR; CYP11B1; Y1 adrenocortical cell
Development of CYP11B1 and CYP11B2 assays utilizing homogenates of adrenal glands: Utility of monkey as a surrogate for human
Keywords: Aldosterone; Aldosterone synthase; Cortisol; CYP11B1; CYP11B2; Cytochrome P450; Inhibitors
An investigation of the endocrine disrupting potential of enniatin B using in vitro bioassays
Keywords: HMGR; hydroxy-methyl-glutaryl CoA reductase; StAR; steroidogenic acute regulatory; CYP11A; cytochrome P450 11A; CYP11B1; cytochrome P450 11B1; CYP11B2; aldosterone synthetase; CYP17; cytochrome P450 17; CYP21; cytochrome P450 21; 3βHSD2; 3-beta-hydroxyst
Development of monoclonal antibodies against human CYP11B1 and CYP11B2
Keywords: CYP11B1; CYP11B2; Adrenal cortex; Monoclonal antibodies; 17α-Hydroxylase; Immunofluorescence;
Adrenal CYP11B1/2 expression in primary aldosteronism: Immunohistochemical analysis using novel monoclonal antibodies
Keywords: CYP11B1; Cytochrome P450, family 11, subfamily B, polypeptide 1; CYP11B2; Cytochrome P450, family 11, subfamily B, polypeptide 2; CYP17; 17α-hydroxylase; NA; normal adrenal gland; IHA; idiopathic hyperaldosteronism; APA; aldosterone-producing adenoma; ZG
Regulation of CYP11B1 and CYP11B2 steroidogenic genes by hypoxia-inducible miR-10b in H295R cells
Keywords: Hypoxia-inducible factor; miR-10b; CYP11B1; CYP11B2; Aldosterone; Cortisol;
Expression of 11β-hydroxysteroid dehydrogenase 1 and 2 in patients with chronic rhinosinusitis and their possible contribution to local glucocorticoid activation in sinus mucosa
Keywords: 11β-Hydroxysteroid dehydrogenase 1; 11β-hydroxysteroid dehydrogenase 2; CYP11B1; CYP11A1; chronic rhinosinusitis with nasal polyps; chronic rhinosinusitis without nasal polyps; glucocorticoid; cortisol; ACTH; Adrenocorticotropic hormone; CRS; Chronic r
Lessons from the gene expression pattern of the rat zona glomerulosa
Keywords: zG; zona glomerulosa; zF; zona fasciculata; zR; zona reticularis; Cyp11b1; steroid 11β-hydroxylase; Cyp11b2; aldosterone synthase; TGF-β; transforming growth factor β; Gpc3; glypican 3; Kcnn2; potassium intermediate/small conductance calcium-activated
Testosterone implants modify the steroid hormone balance and the gonadal physiology of gilthead seabream (Sparus aurata L.) males
Keywords: ISM; in situ forming microparticle implant; T; testosterone; 11KT; 11-ketotestosterone; E2; 17β-estradiol; OHT; 11β-hydroxytestosterone; DHT; dihydrotestosterone; AR; androgen receptor; βdiol; 5α-androstane-3β17β-diol; RCs; reproductive cycles; AGs;
11β-Hydroxyandrostenedione, the product of androstenedione metabolism in the adrenal, is metabolized in LNCaP cells by 5α-reductase yielding 11β-hydroxy-5α-androstanedione
Keywords: 11KA4; 11-ketoandrostenedione; 11KT; 11-ketotestosterone; 11OH-5α-dione; 11β-hydroxy 5α-androstanedione; 11OH-AST; 11β-hydroxyandrosterone; 11OHA4; 11β-hydroxyandrostenedione; 11OHT; 11β-hydroxytestosterone; 11βHSD; 11β-hydroxysteroid dehydrogenas
Flavonoids exhibit diverse effects on CYP11B1 expression and cortisol synthesis
Keywords: Flavonoid; Cortisol; CYP11B1; Ad5; Signaling pathway
Regulation of human CYP11B1 and CYP11B2 promoters by transposable elements and conserved cis elements
Keywords: CYP11B1; CYP11B2; Transposable elements; Ad5; ERRα; SF-1
The influence of Aspalathus linearis (Rooibos) and dihydrochalcones on adrenal steroidogenesis: Quantification of steroid intermediates and end products in H295R cells
Keywords: P450; cytochrome P450; 3βHSD; 3β-hydroxysteroid dehydrogenase II; CYP11A1; cytochrome P450 side-chain cleavage; PREG; pregnenolone; CYP17A1; P450 17α-hydroxylase/1720 lyase; 17OH-PREG; 17-hydroxypregnenolone; DHEA; dehydroepiandrosterone; DHEA-S; dehyd
Adrenocortical stem and progenitor cells: Unifying model of two proposed origins
Keywords: AGP; adrenogonadal primordium; FAdE; fetal adrenal enhancer; DAdE; definitive adrenal enhancer; Sf1; steroidogenic factor 1; E; embryonic day; Shh; sonic hedgehog; Cyp11b1; cytochrome P450, family 11, subfamily b, polypeptide 1; Cyp11b2; cytochrome P450,
The discovery of potent inhibitors of aldosterone synthase that exhibit selectivity over 11-β-hydroxylase
Keywords: CYP11B2; Aldosterone; CYP11B1; Aldosterone synthase inhibitor; Hypertension;
Novel CYP17 inhibitors: Synthesis, biological evaluation, structure–activity relationships and modelling of methoxy- and hydroxy-substituted methyleneimidazolyl biphenyls
Keywords: Prostate cancer; Androgens; 17α-Hydroxylase-17,20-lyase (CYP17) inhibitors; Steroidomimetics; CYP3A4; CYP11B1
Genetics of congenital adrenal hyperplasia
Keywords: congenital adrenal hyperplasia; CAH; genetic analysis; CYP21A2; CYP11B1; CYP17A1; HSD3B2; POR
The prolactin regulatory element-binding regulates of the 11β-hydroxylase gene
Keywords: CYP11B1; Adrenal gland; cAMP; PREB; Transcription
Aldosterone: From biosynthesis to non-genomic action onto the proteome
Keywords: Aldosterone; Non-genomic; CYP11B1; CYP11B2; Schizosaccharomyces pombe
Coexpression of redox partners increases the hydrocortisone (cortisol) production efficiency in CYP11B1 expressing fission yeast Schizosaccharomyces pombe
Keywords: Adrenodoxin; Adrenodoxin reductase; Hydrocortisone; CYP11B1; Fission yeast; Schizosaccharomyces pombe; Steroid 11β-hydroxylation
Interacting influence of potassium and polychlorinated biphenyl on cortisol and aldosterone biosynthesis
Keywords: PCB; Potassium; Adrenal; Cortisol; Aldosterone; CYP11B1; CYP11B2
CYP17- and CYP11B-dependent steroid hydroxylases as drug development targets
Keywords: CYP11B1; CYP11B2; CYP17; Hypertension; Heart fibrosis; Prostate cancerACE, angiotensin-converting enzyme; ADME, absorption, distribution, metabolism, and excretion; AdR, adrenodoxin reductase; Adx, adrenodoxin; AGS (CAH), Adrenogenital syndrome (congenita
Efficient conversion of 11-deoxycortisol to cortisol (hydrocortisone) by recombinant fission yeast Schizosaccharomyces pombe
Keywords: Cortisol; CYP11B1; Directed integration; Fission yeast; Schizosaccharomyces pombe; Steroid 11β-hydroxylation;
Molecular identity and gene expression of aldosterone synthase cytochrome P450
Keywords: Aldosterone synthase; 11β-Hydroxylase; Salt-inducible kinase; CYP11B1; CYP11B2; P450;
The adrenocortical tumor cell line NCI-H295R as an in vitro screening system for the evaluation of CYP11B2 (aldosterone synthase) and CYP11B1 (steroid-11β-hydroxylase) inhibitors
Keywords: CYP11B2; CYP11B1; Inhibitor screening; Selective inhibition; Myocardial fibrosis; Congestive heart failure; Renin-angiotensin-aldosterone system; Adrenocortical tumor cell line NCI-H295R;