دانلود مقالات ISI درباره Cyp1A2 + ترجمه فارسی

کنترل کافئین در تحقیقات قلب و عروق: بررسی انتقادی

Controlling for caffeine in cardiovascular research: A critical review

Keywords: ANS; autonomic nervous system; BP; blood pressure; CNS; central nervous system; CVR; cardiovascular reactivity; CYP1A2; a member of the cytochrome P450 superfamily of enzymes; DBP; diastolic blood pressure; HF-HRV; high-frequency heart rate variability; H

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

تئوبارین بر متابولیسم لیپید پس از غذا و بیان ژن دوازدهه اثر نمی گذارد، اما اثرات نامطلوب آن بر پاسخ گلوکز و پاسخ انسولین بعد از غذا در انسان دارد

Theobromine does not affect postprandial lipid metabolism and duodenal gene expression, but has unfavorable effects on postprandial glucose and insulin responses in humans

Keywords: Theobromine; Postprandial; Lipid metabolism; Glucose metabolism; Microarray; apoA-I; apolipoprotein A-I; apoB100; apolipoprotein B100; apoB48; apolipoprotein B48; CVD; cardiovascular diseases; CYP1A2; cytochrome P450 1A2; CYP2E1; cytochrome P450 2E1; dAUC

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

شبیهسازی متابولیکهای متابولیک در اثر مصرف داروهای فلووکسامین با استفاده از مدل ترکیبی با لولههای دوپایه ترکیبی با دوزهای ترکیبی و تخمینی از کنتراست های مهار کننده درون بدن

Simulation of Metabolic Drug-Drug Interactions Perpetrated by Fluvoxamine Using Hybridized Two-Compartment Hepatic Drug-Pool-Based Tube Modeling and Estimation of In Vivo Inhibition Constants

Keywords: compartment model; CYP1A2; CYP2C19; drug interactions; fluvoxamine; parallel tube model; hepatic clearance; pharmacokinetics; prediction; simulation;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

سطح کافئین و متابولیت های آن در میان سیگاری ها و افراد غیر سیگاری در ایالات متحده

Levels of caffeine and its metabolites among U.S. smokers and nonsmokers

Keywords: Caffeine intake; Race/ethnicity; Smoking; CYP1A2;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

تعاملات بالقوه دارو با ملاتونین

Potential drug interactions with melatonin

Keywords: Melatonin; Drug interactions; 17-Ethinyloestradiol; 5-Methoxypsoralen; CYP1A2;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

از دست دادن گیرنده هیدروکربن آرول به فنوتیپ متمایز کبدی و کلیوی در موش و موش

Knockout of the aryl hydrocarbon receptor results in distinct hepatic and renal phenotypes in rats and mice

Keywords: AHR; aryl hydrocarbon receptor; AHR-KO; aryl hydrocarbon receptor knockout; Ahrr; aryl hydrocarbon receptor repressor; AIP; aryl hydrocarbon receptor interacting protein; ALB; serum albumin; ALP; alkaline phosphatase; ALT; alanine aminotransferase; ARNT;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

Evaluation of the impact of CYP1A2 induction by charbroiled meal on metabolic phenotype

Keywords: CYP1A2; Induction; Inhibition; Charbroiled meal; Caffeine; Metabolic phenotype;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2018 سفارش ترجمه

Probing cytochrome P450 bioactivation and fluorescent properties with morpholinyl-tethered anthraquinones

Keywords: Anthraquinone; Nemorubicin; MMDX; DRAQ5; Cytochrome P450; CYP1A2; Fluorophore; Cancer;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2018 سفارش ترجمه

The immunobiology and clinical features of type 1 autoimmune polyglandular syndrome (APS-1)

Keywords: APS-1; type 1 autoimmune polyglandular syndrome; AIRE; autoimmune regulator; mTECs; medullary thymic epithelial cells; CMC; chronic mucocutaneous candidiasis; T1D; type 1 diabetes; PGA I; polyglandular type I autoimmune syndrome; IFN; interferon; AIH; aut

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Ahr and Cyp1a2 genotypes both affect susceptibility to motor deficits following gestational and lactational exposure to polychlorinated biphenyls

Keywords: Polychlorinated biphenyls; Aryl hydrocarbon receptor; CYP1A2; Nigrostriatal pathways; Motor function; Cerebellum;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Recent technical and biological development in the analysis of biomarker N-deoxyguanosine-C8-4-aminobiphenyl

Keywords: 4-ABP; 4-aminobiphenyl; dG-C8-4-ABP; N-deoxyguanosine-C8-4-aminobiphenyl; LC-MS; liquid chromatography-mass spectrometry; PAHs; polycyclic aromatic hydrocarbons; NOCs; N-nitroso compounds; AAs; aromatic amines; CYP1A2; cytochrome P450 1A2; N-OH-ABP; N-hyd

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

The influence of CYP1A2 genotype in the blood pressure response to caffeine ingestion is affected by physical activity status and caffeine consumption level

Keywords: CYP1A2; Caffeine; Blood pressure; Physical activity; Caffeine consumption;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

Upregulation of microRNA-320 decreases the risk of developing steroid-induced avascular necrosis of femoral head by inhibiting CYP1A2 both in vivo and in vitro

Keywords: MicroRNA-320; CYP1A2; Steroid-induced avascular necrosis of femoral head; Rat model;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

β-Naphthoflavone treatment attenuates neonatal hyperoxic lung injury in wild type and Cyp1a2-knockout mice

Keywords: Hyperoxia; Neonate; Bronchoplumonary dysplasia; CYP1A2; Beta-naphthoflavone;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

Dietary effects of Sideritis scardica “mountain tea” on human in vivo activities of xenobiotic metabolizing enzymes in healthy subjects

Keywords: Sideritis; CYP1A2; CYP2A6; Xanthine oxidase; NAT2; UDPGlucuronosyltransferases 1A1/1A6;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

The genetic profiles of CYP1A1, CYP1A2 and CYP2E1 enzymes as susceptibility factor in xenobiotic toxicity in Turkish population

Keywords: Genetic polymorphism; Turkish population; CYP1A1; CYP1A2; CYP2E1; Cytochrome P450;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

Activated thyroid hormone receptor modulates dioxin-inducible aryl hydrocarbon receptor-mediated CYP1A1 induction in human hepatocytes but not in human hepatocarcinoma HepG2 cells

Keywords: Triiodothyronine; CYP1A2; S14; Receptors cross-talk; Dioxin receptor;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

CYP1A2 is a predictor of HCC recurrence in HCV-related chronic liver disease: A retrospective multicentric validation study

Keywords: CYP1A2; HCC; Immunocytochemistry; Liver biopsy; Outcome; Translational biomarkers;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Short communicationDifferential protein expression and localization of CYP450 enzymes in three species of earthworm; is this a reflection of environmental adaptation?

Keywords: Earthworm; CYP450; CYP1A2; CYP2E1; CYP3A4; Western blot;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Pharmacogenetics of ecstasy: CYP1A2, CYP2C19, and CYP2B6 polymorphisms moderate pharmacokinetics of MDMA in healthy subjects

Keywords: 3,4-Methylenedioxymethamphetamine; 3,4-Methylenedioxyamphetamine; Pharmacokinetics; CYP1A2; CYP2C19; CYP2B6;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Cytochrome P450 binding studies of novel tacrine derivatives: Predicting the risk of hepatotoxicity

Keywords: Cholinesterase inhibitors; Tacrine; Hepatotoxicity; Cytochrome P450; CYP1A2; CYP3A4; Molecular docking; 3,4-Dimethoxybenzylamino;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Effects of peppermint tea consumption on the activities of CYP1A2, CYP2A6, Xanthine Oxidase, N-acetyltranferase-2 and UDP-glucuronosyltransferases-1A1/1A6 in healthy volunteers

Keywords: Peppermint; CYP1A2; CYP2A6; Xanthine Oxidase; N-Acetyltranferase-2; UDP-Glucuronosyltransferases 1A1/1A6;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Investigation of substrate recognition for cytochrome P450 1A2 mediated by water molecules using docking and molecular dynamics simulations

Keywords: CYP1A2; Docking; Molecular dynamics; Water; Ligand recognition;

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2017 سفارش ترجمه

The expression, induction and pharmacological activity of CYP1A2 are post-transcriptionally regulated by microRNA hsa-miR-132-5p

Keywords: CYP; cytochrome P450; miRNAs; microRNAs; DMETs; drug metabolizing enzymes and transporters; Ago; argonaute RISC catalytic component; RISC; RNA-induced silencing complex; FBS; fetal bovine serum; EMSA; electrophoretic mobility shift assay; HCC; hepatocellu

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2017 سفارش ترجمه

Effect of Bakumondo-to on cytochrome P450 activities in rat liver microsomes

Keywords: Bakumondo-to; CYP1A2; CYP2C; CYP3A; Interaction

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Quand l'ésoméprazole induit une résistance à la fluindione : une interaction méconnue

Keywords: Fluindione; Ésoméprazole; Induction enzymatique; CYP1A2; Fluindione; Esomeprazole; Enzymatic induction; CYP1A2;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Effects of Hypericum perforatum extract and its main bioactive compounds on the cytotoxicity and expression of CYP1A2 and CYP2D6 in hepatic cells

Keywords: Hypericum perforatum; Hypericin; Hyperforin; CYP1A2; CYP2D6; Hepatic cells; Herb-drug interactions

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Prediction of inter-individual variability on the pharmacokinetics of CYP1A2 substrates in non-smoking healthy volunteers

Keywords: CYP1A2; Inter-individual variability; Monte Carlo simulation; Human pharmacokinetics; Drug development;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

An assessment of dioxin exposure across gestation and lactation using a PBPK model and new data from Seveso

Keywords: acslX®; Advanced Continuous Simulation Language; AhR; aryl hydrocarbon receptor; AUC; area under the curve; CYP1A; Cytochrome P4501A; CYP1A2; Cytochrome P4501A2; CYP1B; Cytochrome P4501B; EPA; U.S. Environmental Protection Agency; GI; gastrointestinal; I

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Expression of CYP1A1 and CYP1A2 in the liver and kidney of rabbits after prolonged infusion of propofol

Keywords: Propofol; Propofol metabolism; Rabbit anesthesia; CYP1A1; CYP1A2; Immunohistochemistry;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Dynamic and Static Simulations of Fluvoxamine-Perpetrated Drug-Drug Interactions Using Multiple Cytochrome P450 Inhibition Modeling, and Determination of Perpetrator-Specific CYP Isoform Inhibition Constants and Fractional CYP Isoform Contributions to Vic

Keywords: compartment model; cytochrome P450; CYP1A2; drug interactions; fluvoxamine; parallel tube model; hepatic clearance; pharmacokinetics; prediction; simulations;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Analysis of caffeine and paraxanthine in human saliva with ultra-high-performance liquid chromatography for CYP1A2 phenotyping

Keywords: Caffeine; Paraxanthine; CYP1A2; Phenotyping; Saliva; UHPLC

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2015 سفارش ترجمه

Functional characterization of 20 allelic variants of CYP1A2

Keywords: Cytochrome P450; CYP1A2; Genetic polymorphism; Phenacetin; 7-Ethoxyresorufin

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

CYP1A1 and CYP1A2 expression levels are differentially regulated in three-dimensional spheroids of liver cancer cells compared to two-dimensional monolayer cultures

Keywords: CYP1A1; CYP1A2; Aryl hydrocarbon receptor; Pregnane X receptor; 3D culture; Spheroid; Liver cancer

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Theoretical study on the N-demethylation mechanism of theobromine catalyzed by P450 isoenzyme 1A2

Keywords: Theobromine; N-demethylation mechanism; CYP1A2; Metabolism; Density function theory; Dispersion correction

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Subacute nicotine co-exposure has no effect on 2,2′,3,5′,6- pentachlorobiphenyl disposition but alters hepatic cytochrome P450 expression in the male rat

Keywords: Ct; fractional amplification (cycle number at which fluorescence exceeds a user-defined threshold); d; day; b.w.; body weight; DE; diatomaceous earth; EF; enantiomeric fraction; qPCR; quantitative (real-time) polymerase chain reaction; PCBs; polychlorinat

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Aire-dependent peripheral tissue antigen mRNAs in mTEC cells feature networking refractoriness to microRNA interaction

Keywords: Thymus; Aire gene; Peripheral tissue antigen; Post-transcriptional control; Self-tolerance; microRNAs; AID; autoimmune disease; Amelx; amelogenin X chromosome; Amy1; amylase 1, salivary; ANOVA; analysis of variance; Aire; autoimmune regulator; Alb; albumi

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

In vitro effect of important herbal active constituents on human cytochrome P450 1A2 (CYP1A2) activity

Keywords: Herbal active constituents; CYP1A2; Fluorescence-based enzyme assay; Inhibitory effect; CEC; 3-cyano-7-ethoxycoumarin; CYP; cytochrome P450; DMSO; dimethylsulfoxide; Km; Michaelis-Menten constant; Vmax; maximum velocity; IC50; the half maximal (50%) inh

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Calcium channel blocker verapamil accelerates gambogic acid-induced cytotoxicity via enhancing proteasome inhibition and ROS generation

Keywords: GA; gambogic acid; Ver; verapamil; Ab; antibody; ER; endoplasmic reticulum; ROS; reactive oxygen species; z-VAD-FMK; carbobenzoxy-valyl-alanyl-aspartyl-(O-methyl)-fluoromethylketone; CT-like; chymotrypsin-like; DCFH-DA; 2′,7′-dichlorfluorescein-diacet

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibition of cytochrome P450 by ethambutol in human liver microsomes

Keywords: Ethambutol; Drug-drug interaction; CYP1A2; CYP2E1; Theophylline;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

RO4938581, a GABAAα5 modulator, displays strong CYP1A2 autoinduction properties in rats

Keywords: Autoinduction; CYP1A2; Contextual fear conditioning; Rat liver; Pharmacokinetics;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Design and synthesis of novel benzimidazole derivatives as phosphodiesterase 10A inhibitors with reduced CYP1A2 inhibition

Keywords: PDE10A inhibitor; Schizophrenia; Benzimidazole; CYP1A2;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

In vitro evaluation of cytochrome P450 induction and the inhibition potential of mitragynine, a stimulant alkaloid

Keywords: Mitragynine; CYP1A2; CYP3A4; CYP450 induction assay; CYP450 inhibition assay; Drug-herb interactions;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Consumption of baby kale increased cytochrome P450 1A2 (CYP1A2) activity and influenced bilirubin metabolism in a randomized clinical trial

Keywords: BHNRC; Beltsville Human Nutrition Research Center; CYP1A2; cytochrome P450 family 1 subfamily A member 2; CYP2A6; cytochrome P450 family 2 subfamily A member 6; CV; control vegetables; GST; glutathione S-transferase; GSTA; glutathione S-transferase alpha;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2020 سفارش ترجمه

Pharmacokinetic changes of unbound theophylline are due to plasma protein binding displacement and CYP1A2 activity inhibition by baicalin in rats

Keywords: Baicalin; Theophylline; Pharmacokinetics; Plasma protein binding; CYP1A2

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

The Influence of Smoking Status on the Pharmacokinetics and Pharmacodynamics of Clopidogrel and Prasugrel : The PARADOX Study

Keywords: clopidogrel; CYP1A2; CYP2C19; pharmacodynamics; pharmacokinetics; platelet; prasugrel; smokingAM, active metabolite; AUC, area under the curve; CAD, coronary artery disease; CI, confidence interval; C-IPA, calculated inhibition of platelet aggregation; CY

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Mercury modulates the cytochrome P450 1a1, 1a2 and 1b1 in C57BL/6J mice: in vivo and in vitro studies

Keywords: AhR, aryl hydrocarbon receptor; Hg2 +, mercury chloride; Cyp450s, cytochrome P450s; HO-1, heme oxygenase-1; TCDD, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD); XRE, xenobiotic responsive elementAhR; Mercury; Cyp1a1; Cyp1a2; Cyp1b1; TCDD; C57BL/6J; Hepatocyt

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Glutathione S-transferase M1 and T1, CYP1A2-2467T/delT polymorphisms and non small-cell lung cancer risk in Tunisian sample

Keywords: GSTT1; GSTTM1; CYP1A2; Polymorphisms; Lung cancer

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Cytochrome P450 inhibitory potential of selected Indian spices - possible food drug interaction

Keywords: Indian spices; Cytochrome P450; Standardization; CYP3A4; CYP2D6; CYP2C9; CYP1A2; Food-drug interaction;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Association of the ADRA1A gene and the severity of metabolic abnormalities in patients with schizophrenia

Keywords: ADRA1A; adrenergic alpha1A receptor; ADRB3; adrenergic beta3 receptor; ANOVA; analysis of variance; BMI; body mass index; BP; blood pressure; CI; confidence interval; CYP1A2; cytochrome P450 1A2; DSM-IV-TR; Diagnostic and Statistical Manual of Mental Diso

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه