دانلود مقالات ISI درباره Cyp24A1 + ترجمه فارسی

Novel styryl-indoles as small molecule inhibitors of 25-hydroxyvitamin D-24-hydroxylase (CYP24A1): Synthesis and biological evaluation

Keywords: Imidazole styrylindoles; Sulfonyl styrylindoles; CYP24A1; Vitamin D; Molecular modelling;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Prevention of preneoplastic lesions by dietary vitamin D in a mouse model of colorectal carcinogenesis

Keywords: Vitamin D; Colorectal cancer; Dysplasia; Chemoprevention; cyp24a1; cyp27b1;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

24-Hydroxylase in cancer: Impact on vitamin D-based anticancer therapeutics

Keywords: CYP24A1; 24-Hydroxylase; Calcitriol; Anti-tumor;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

The novel purification and biochemical characterization of a reversible CYP24A1:adrenodoxin complex

Keywords: P450 or CYP; cytochrome P450; CYP24A1; cytochrome P450 24A1; 25(OH)D3; 25-hydroxyvitamin-D3; 1,25(OH)2D3; 1α,25-dihydroxyvitamin-D3; 1,25(OH)2D2; 1α,25-dihydroxyvitamin-D2; Adx; adrenodoxin; CHAPS; 3-[(3-cholamidopropyl)dimethylammonio]-2-hydroxy-1-prop

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Human cytochrome P450-dependent differential metabolism among three 2α-substituted-1α,25-dihydroxyvitamin D3 analogs

Keywords: 25(OH)D3; 25-hydroxyvitamin D3; 1α,25(OH)2D3; 1α,25-dihydroxyvitamin D3; 1α,2α,25(OH)3D3; 1α,2α,25-trihydroxyvitamin D3; P450; cytochrome P450; UGT; UDP-glucuronosyltransferase; Glc-UA; glucuronic acid; HPLC; high-performance liquid chromatography;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Vitamin D in thyroid tumorigenesis and development

Keywords: 1,25(OH)2D3; 1α,25-dihydroxyvitamin D3; 25-OHD3; 25-hydroxyvitamin D3; ATC; anaplastic thyroid cancer; CDK; cyclin-dependent kinase; CDKI; cyclin-dependent kinase inhibitor; CEA; carcinoembryogenic antigen; CT; calcitonin; CYP24A1; 24-hydroxylase; CYP27B

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2013 سفارش ترجمه

Probing the structural requirements for vitamin D3 inhibition of the hedgehog signaling pathway

Keywords: Hedgehog pathway; Vitamin D3; Vitamin D2; Gli1; Cyp24A1; Vitamin D receptor

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Evaluation of vitamin D3 A-ring analogues as Hedgehog pathway inhibitors

Keywords: Hedgehog pathway; Vitamin D3; Vitamin D receptor; Gli1; Cyp24A1

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Regulation of mouse Cyp24a1 expression via promoter-proximal and downstream-distal enhancers highlights new concepts of 1,25-dihydroxyvitamin D3 action

Keywords: Cyp24a1; 1,25(OH)2D3; VDR/RXR heterodimer; C/EBPβ; Transcription; Distal enhancers; ChIP-seq analysis

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Non-genomic effects of vitamin D in human spermatozoa

Keywords: CYP24A1; Progesterone; Calcium; Rapid effects; Steroid receptor; CatSper

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Phorbol esters enhance 1α,25-dihydroxyvitamin D3-regulated 25-hydroxyvitamin d-24-hydroxylase (CYP24A1) gene expression through ERK-mediated phosphorylation of specific protein 3 (Sp3) in Caco-2 cells

Keywords: 1,25(OH)2D3; 1,25-dihydroxyvitamin D3; 25(OH)D3; 25-hydroxyvitamin D3; CYP24A1; 25-hydroxyvitamin D,24-hydroxylase; CYP27B1; 1 alpha hydroxylase; TRPV6; transient receptor potential cation channel, subfamily V, member 6; Sp1; specific protein 1; Sp3; spec

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Rat CYP24A1 acts on 20-hydroxyvitamin D3 producing hydroxylated products with increased biological activity

Keywords: CYP24A1; Vitamin D metabolism; 20-Hydroxyvitamin D; Phospholipid vesicles; Melanoma; (20(OH)D3); 20S-hydroxyvitamin D3; (25(OH)D3); 25-hydroxyvitamin D3; (20,24(OH)2D3); 20S,24-dihydroxyvitamin D3; (20,25(OH)2D3); 20S,25-dihydroxyvitamin D3; (20,26(OH)2D3

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

25-Hydroxyvitamin D-24-hydroxylase (CYP24A1): Its important role in the degradation of vitamin D

Keywords: CYP24A1; 25-Hydroxyvitamin D3; 1,25-Dihydroxyvitamin D3; Catabolism; Gene mutations; Idiopathic infantile hypercalcemia; CYP24A1 null-mouse; FGF-23

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Vitamin D, the placenta and pregnancy

Keywords: Vitamin D; Preeclampsia; Preterm birth; Placenta; Decidua; VDR; CYP27B1; CYP24A1

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Synthesis and biological activities of vitamin D-like inhibitors of CYP24 hydroxylase

Keywords: 1,25-Dihydroxyvitamin D3; Cytochrome P450 inhibitors; CYP24A1; Cyclopropylamines; Cancer therapy; Molecular docking

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Vitamin D metabolism in mammary gland and breast cancer

Keywords: Vitamin D; Mammary; Breast cancer; CYP27B1; VDR; CYP24A1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

The ratio of serum 24,25-dihydroxyvitamin D3 to 25-hydroxyvitamin D3 is predictive of 25-hydroxyvitamin D3 response to vitamin D3 supplementation

Keywords: 24,25-Dihydroxyvitamin D; 25-Hydroxyvitamin D; Vitamin D; Supplementation; Catabolism; CYP24A1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Calcitriol stimulates prolactin expression in non-activated human peripheral blood mononuclear cells: Breaking paradigms

Keywords: Calcitriol; 1,25-dihydroxyvitamin D3; EC50; half maximal effective concentration; PBMNC; peripheral blood mononuclear cells; PHA; phytohemagglutinin; PXR; pregnane X receptor; PRL; prolactin; qPCR; real time polymerase chain reaction; RXR; retinoid X rece

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Vitamin D metabolism, cartilage and bone fracture repair

Keywords: Chondrocytes; Cyp27b1; 1,25-Dihydroxyvitamin D; Vitamin D receptor; Cyp24a1; 24,25-Dihydroxyvitamin D

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Genome-wide principles of gene regulation by the vitamin D receptor and its activating ligand

Keywords: ChIP-seq; VDR; Enhancers; Acetylation; CYP24A1; Tnfsf11/Rankl

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Regulation of vitamin D metabolism

Keywords: vitamin D; 25-hydroxyvitamin D3; 1,25-dihydroxyvitamin D3; 24; 25-dihydroxyvitamin D3; metabolism; hydroxylase; CYP2R1′ CYP27B1; CYP24; CYP24A1; parathyroid hormone (PTH); fibroblast growth factor 23 (FGF23)

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

CYP24A1 splice variants—Implications for the antitumorigenic actions of 1,25-(OH)2D3 in colorectal cancer

Keywords: Vitamin D3; CYP24A1; Splicing variant; Colorectal cancer

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Human breast tumor slices: A model for identification of vitamin D regulated genes in the tumor microenvironment

Keywords: Breast cancer; Vitamin D; Tumor microenvironment; Tissue slices; CYP24A1; BrDU

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Genome-wide analysis of the VDR/RXR cistrome in osteoblast cells provides new mechanistic insight into the actions of the vitamin D hormone

Keywords: VDR; RXR; ChIP-chip; Genome-wide; RNA polymerase II; Cyp24a1; Spp1; Opn; Rarβ; Prkca; Cistrome; 1,25(OH)2D3; Vitamin D3; Epigenetics; Histone acetylation; Distal enhancers;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Synthesis and CYP24A1 inhibitory activity of N-(2-(1H-imidazol-1-yl)-2-phenylethyl)arylamides

Keywords: N-(2-(1H-Imidazol-1-yl)-2-phenylethyl)arylamides; Benzofuran-2-carboxamides; CYP24A1; Enzyme inhibition; Molecular modelling;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Synthesis and CYP24A1 inhibitory activity of (E)-2-(2-substituted benzylidene)- and 2-(2-substituted benzyl)-6-methoxy-tetralones

Keywords: Benzylidene tetralones; Benzyl tetralones; CYP24A1; CYP27A1; Enzyme inhibition; Molecular modelling

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Systematic characterisation of the rat and human CYP24A1 promoter

Keywords: Promoter; CYP24A1; Vitamin D; VSE; Stimulation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

The nuclear vitamin D receptor controls the expression of genes encoding factors which feed the “Fountain of Youth” to mediate healthful aging

Keywords: Vitamin D receptor; 1,25-Dihydroxyvitamin D3; Calcium metabolism; Phosphate metabolism; Fibroblast growth factor 23; Klotho; CYP24A1; Osteocalcin (BGP); Osteopontin (SSP1); LRP5; TRPV6; RANKL; OPG; β-Catenin; Hairless; S100A8; SOSTDC1

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Calcitriol inhibits TNF-α-induced inflammatory cytokines in human trophoblasts

Keywords: Preeclampsia; Vitamin D antagonist; CYP24A1; IL-6; VDR; CYP19

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

A novel SNP in a vitamin D response element of the CYP24A1 promoter reduces protein binding, transactivation, and gene expression

Keywords: CYP24A1; 24-Hydroxylase; Promoter; 1α,25(OH)2D3; Vitamin D receptor; Single nucleotide polymorphism; VDRE

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Specific regulation of CYP27B1 and VDR in proximal versus distal renal cells

Keywords: Vitamin D receptor; Kidney; Parathyroid hormone; CYP27B1; CYP24A1; Proximal tubule; Distal tubule; MPCT; DKC-8 cells

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Reduction of the vitamin D hormonal system in kidney disease is associated with increased renal inflammation

Keywords: VDR; inflammation; vitamin D; CYP27B1; CYP24A1; chronic kidney disease

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Regulation of Vitamin D hydroxylases gene expression by 1,25-dihydroxyvitamin D3 and cyclic AMP in cultured human syncytiotrophoblasts

Keywords: CYP27B1; CYP24A1; VDR; Calcitonin; Trophoblast; Gene expression

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Hybrid homology modeling and mutational analysis of cytochrome P450C24A1 (CYP24A1) of the Vitamin D pathway: Insights into substrate specificity and membrane bound structure–function

Keywords: Vitamin D; Calcitriol; 25-hydroxyvitamin D3 24R-hydroxylase; 1,25-dihydroxyvitamin D3; Vitamin D inactivation; Cytochrome P450; CYPs; P450C24A1; CYP24A1; Site-directed mutagenesis; Homology modeling; Affinity labeling; Monotopic membrane protein

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

Generation of a homology model for the human cytochrome P450, CYP24A1, and the testing of putative substrate binding residues by site-directed mutagenesis and enzyme activity studies

Keywords: Vitamin D; Calcitriol; Cytochrome P450; CYP24A1; Homology modeling, 1α,25(OH)2D3; Mutagenesis; Vitamin D dependent-gene expression; Vitamin D analogs; CYP24A1 inhibitors

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2007 سفارش ترجمه

Monocyte-derived cells express CYP27A1 and convert vitamin D3 into its active metabolite

Keywords: Monocyte; Macrophage; Dendritic cell; Active vitamin D3; CYP27A1; CYP27B1; CYP24A1

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه

Kidney-specific upregulation of vitamin D3 target genes in ClC-5 KO mice

Keywords: chloride channel; channelopathy; nephrolithiasis; nephrocalcinosis; CYP27B1; CYP24A1

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

23-Carboxy-24,25,26,27-tetranorvitamin D3 (calcioic acid) and 24-carboxy-25,26,27-trinorvitamin D3 (cholacalcioic acid): End products of 25-hydroxyvitamin D3 metabolism in rat kidney through C-24 oxidation pathway

Keywords: 25OHD3; 24R,25(OH)2D3; Rat kidney; Metabolism; CYP24A1; Calcioic acid; Cholacalcioic acid; Bile acid; Vitamin D3

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه