دانلود مقالات ISI درباره Cyp450 + ترجمه فارسی

Analysis of the Dendrobium officinale transcriptome reveals putative alkaloid biosynthetic genes and genetic markers

Keywords: BLAST; Basic Local Alignment Search Tool; CYP450; cytochrome P450-dependent monooxygenase; EC; enzyme commission; ESTs; expressed sequence tags; G10H; geraniol 10-hydroxylase; GO; Gene Ontology; HQ; high-quality; KEGG; Kyoto Encyclopedia of Genes and Geno

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Cylindrospermopsin induced transcriptional responses in human hepatoma HepG2 cells

Keywords: AP-1; activator protein; BER; base excision repair; CDK; cyclin-dependant kinase; CDKI; cyclin-dependant kinase inhibitor; CYN; cylindrospermopsin; CYP450; cytochrome P450; DSB; DNA double-strand break; ER; endoplasmic reticulum; GST; glutathione S-transf

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

In vitro metabolism study of the promising anticancer agent the lignan (−)-grandisin

Keywords: Grandisin; In vitro metabolism; Method validation; CYP450; Rat liver microsomes; Dihydro-grandisin metabolite

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Inhibiteurs de la pompe à protons et clopidogrel (Plavix®) : une liaison dangereuse ?

Keywords: Clopidogrel; Thiénopyridines; Inhibiteurs de pompes à protons; Interactions médicamenteuses; CYP450; CYP2C19Clopidogrel; Thienopyridines; Proton pump inhibitors; Drug-drug interaction; CYP450; CYP2C19

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Effects of unprocessed versus vinegar-processed Schisandra chinensis on the activity and mRNA expression of CYP1A2, CYP2E1 and CYP3A4 enzymes in rats

Keywords: Schisandra chinensis; Vinegar-processed; CYP450; Pharmacokinetic; Cocktail; mRNA; Real-time RT-PCR

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Selenium and/or iodine deficiency alters hepatic xenobiotic metabolizing enzyme activities in rats

Keywords: Iodine deficiency; Selenium deficiency; Combined iodine and selenium deficiency; Thyroid hormones; Xenobiotic metabolizing enzymes; CYP450

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Endothelial nitric oxide and 15-lipoxygenase-1 metabolites independently mediate relaxation of the rabbit aorta

Keywords: AA; arachidonic acid; 15-LO-1; 15-lipoxygenase-1; THETA; 11,12,15-trihydroxyeicosatrienoic acid; HEETA; 15-hydroxy-11,12-epoxyeicosatrienoic acid; NO; nitric oxide; ACH; acetylcholine; LNA; nitro-l-arginine; LO; lipoxygenase; GC; guanylate cyclase; NDGA;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Cross-sectional study of hepatic CYP1A and CYP3A enzymes in hybrid striped bass, channel catfish and Nile tilapia following oxytetracycline treatment

Keywords: BFC, 7-benzyloxy-4-trifluoromethylcoumarin; BzRes, resorufin benzyl ether; CEC, 3-cyano-ethoxycoumarin; CYP, cytochrome P450; EROD, 7-ethoxyresorufin O-deethylaseHybrid striped bass; Channel catfish; Nile tilapia; Oxytetracycline; CYP450; CYP1A1; CYP1A2;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Furocoumarins affect hepatic cytochrome P450 and renal organic ion transporters in mice

Keywords: Furocoumarins; CYP450; Organic ion transporters; Liver and kidney toxicology

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Bile salt export pump inhibitors are associated with bile acid-dependent drug-induced toxicity in sandwich-cultured hepatocytes

Keywords: 1-ABT; 1-aminobenzotriazole; BA; bile acid; BSEP/Bsep; human/rat bile salt export pump; CYP450; cytochrome P450; DILI; drug-induced liver injury; IC50; 50% inhibitory concentration; Ki; inhibition constant; LDH; lactate dehydrogenase; NAPQI; N-acetyl-p-be

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Cytochrome P450 1 enzyme inhibition and anticancer potential of chromene amides from Amyris plumieri

Keywords: CYP450, cytochrome P450; PAH, polycyclic aromatic hydrocarbon; AhR, aryl hydrocarbon receptor; DMBA, 7,12-dimethylbenz(a)anthracene; B[a]P, benzo-a-pyreneAnticancer; CYP450; Chemoprotection; Chemoprevention; Natural products; Jamaica

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Lipopolysaccharide down-regulates carbolesterases 1 and 2 and reduces hydrolysis activity in vitro and in vivo via p38MAPK-NF-κB pathway

Keywords: LPS; lipopolysaccharide; NS; normal saline; HCE1; human carboxylesterases 1; HCE2; human carboxylesterases 2; mCE1; mouse carboxylesterases 1; mCE2; mouse carboxylesterases 2; CYP450; cytochrome P450; DMEs; drug metabolism enzymes; PXR; pregnane X recepto

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Effect of strychnine hydrochloride on liver cytochrome P450 mRNA expression and monooxygenase activities in rat

Keywords: STN, strychnine; SH, strychnine hydrochloride; GA, glycyrrhetic acid; LQ, liquiritin; EROD, ethoxyresorufin-O-deethylation; Tol-OH, tolbutamide hydroxylation; 6βTesto-OH, testosterone 6β-hydroxylationStrychnine; CYP450; Compatibility; Glycyrrhetic acid; L

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Andrographolide-induced pi class of glutathione S-transferase gene expression via PI3K/Akt pathway in rat primary hepatocytes

Keywords: AP-1; activator protein 1; CYP450; cytochrome P450; DMSO; dimethylsulfoxide; EMSA; electrophoretic mobility shift assay; ERK; extracellular signal-regulated kinase; GPE1; GSTP enhancer 1; GST; glutathione S-transferase; GSTP; pi class of GST; HEPES; N-[2-

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

A cocktail of metabolic probes demonstrates the relevance of primary human hepatocyte cultures in a microfluidic biochip for pharmaceutical drug screening

Keywords: CIME; carte d'Identité MEtabolique; CYP450; cytochrome P450; UGT; uridine diphosphate glucuronosyltransferase; UGT 1A1; uridine diphosphate-glucuronosyltransferase 1 polypeptide 1A; UGT 2B7; uridine diphosphate-glucuronosyltransferase 2 polypeptide 7B;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Downregulation of basophil-derived IL-4 and in vivo TH2 IgE responses by serotonin and other organic cation transporter 3 ligands

Keywords: Basophils; IL-4; TH2-type immune response; organic cation transporter 3; 5-HT; 5-Hydroxytryptamine; BMC; Bone marrow cell; BMDB; Bone marrow-derived basophil; CYP450; Cytochrome P450; Dat; Dopamine transporter; DNP; Dinitrophenyl; Gapdh; Glyceraldehyde-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Reversible time-dependent inhibition of cytochrome P450 enzymes by duloxetine and inertness of its thiophene ring towards bioactivation

Keywords: ACN; acetonitrile; APAP; acetaminophen; CYP1A2; cytochrome P450 1A2 enzyme; CYP2B6; cytochrome P450 2B6 enzyme; CYP2C19; cytochrome P450 2C19 enzyme; CYP2D6; cytochrome P450 2D6 enzyme; CYP3A4; cytochrome P450 3A4 enzyme; CYP450; cytochrome P450 enzymes;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Acute administration of 3,4-methylenedioxymethamphetamine (MDMA) induces oxidative stress, lipoperoxidation and TNFα-mediated apoptosis in rat liver

Keywords: AA; ascorbic acid; α - Me Da; α - methyldopamine; A-SMase; acidic sphingomyelinase; ATP; adenosintriphosfato; Bax/Bak; BCL2-associated X protein/BCL2-antagonist/killer 1; Bcl-2; B cell lymphoma gene-2; BHT; butylhydroxytoluene; BID; BH3-interacting

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Biomarker responses in the bivalve (Chlamys farreri) to exposure of the environmentally relevant concentrations of lead, mercury, copper

Keywords: Heavy metal; Antioxidant enzyme; CYP450; Biomarker; Bivalve

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Transcriptional and post-transcriptional response of drug-metabolizing enzymes to PAHs contamination in red mullet (Mullus barbatus, Linnaeus, 1758): A field study

Keywords: Mullus barbatus; PAHs; CYP450; MRP2; GST; UDPGT

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Ellagitannins, ellagic acid and vascular health

Keywords: ACE; angiotensin converting enzyme; ACO; acyl CoA oxidase; AMPK; 5′-AMP activated protein kinase; ApoB; apolipoprotein B; COMT; catechol ortho methyl transferase; CPT; carnitine palmitoyl transferase; CRP; C-reactive protein; CYP450; cytochrome P450; d.

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2010 سفارش ترجمه

Human hepatic CYP2B6 developmental expression: The impact of age and genotype

Keywords: CYP450; Ontogeny; CYP2B6; CYP3A; Hepatic

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Equine cytochrome P450 2C92: cDNA cloning, expression and initial characterization

Keywords: CYP450; Horse; CYP2C; Diclofenac; Mephenytoin; Tolbutamide; Warfarin; Phase I metabolism

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

The effects of accumulation of an environmentally relevant polychlorinated biphenyl mixture on cytochrome P450 and P-glycoprotein expressions in fetuses and pregnant rats

Keywords: P-170 glycoprotein; Rat; PCB levels; Pregnancy; Fetus; CYP450

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

The binding of lignans, flavonoids and coumestrol to CYP450 aromatase: A molecular modelling study

Keywords: CYP450; Aromatase; Phytoestrogen; Molecular modelling; Lignan; Enterolactone; Flavone; Isoflavone

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Cunninghamella – A microbial model for drug metabolism studies – A review

Keywords: Biotransformation; Cunninghamella; CYP450; Drug; In vitro metabolism study; Microbial metabolites; Microbial model; Metabolism; Metabolites

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2009 سفارش ترجمه

Inhibition of arachidonic acid metabolism and its implication on cell proliferation and tumour-angiogenesis

Keywords: Arachidonic acid; COX inhibitors; LOX inhibitors; CYP450; Cancer

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2009 سفارش ترجمه

Characterization of the two major CYP450 metabolites of ozonide (1,2,4-trioxolane) OZ277

Keywords: 1,2,4-Trioxolane; Ozonide; Antimalarial; Synthetic peroxide; CYP450

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Complementary DNA cloning, functional expression and characterization of a novel cytochrome P450, CYP2D50, from equine liver

Keywords: CYP450; Horse; CYP2D; Dextromethorphan; Debrisoquine; Phase I metabolism

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Expression of CYP4F2 in human liver and kidney: Assessment using targeted peptide antibodies

Keywords: CYP450; CYP4F2; Fatty acids; Eicosanoids; ω-Hydroxylation; Peptide antibodies

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Effect of subacute methyl parathion administration on the pharmacokinetics and pharmacodynamics of nifedipine in rats

Keywords: Methyl parathion; Organophosphate pesticides; Nifedipine; CYP450; Rats;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Mechanisms by which epoxyeicosatrienoic acids (EETs) elicit cardioprotection in rat hearts

Keywords: CYP450; 8,9-EET; 11,12-EET; 14,15-EET; Reactive oxygen species; Mito- and sarcKATP channels

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Tolerability of statins is not linked to CYP450 polymorphisms, but reduced CYP2D6 metabolism improves cholesteraemic response to simvastatin and fluvastatin

Keywords: Statins; Muscle toxicity; CYP450; Enzyme polymophisms; Cholesteraemic response; Apo E allele variants

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

A three-dimensional model of CYP19 aromatase for structure-based drug design

Keywords: Aromatase; CYP450; CYP2C5; Structure-based drug design; Breast cancer; Homology modeling; Molecular dynamics

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Negative urine opioid screening caused by rifampin-mediated induction of oxycodone hepatic metabolism

Keywords: Oxycodone screen; GC/MS; CYP450; Pharmacogenetics; Rifampin;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه

The AmpliChip CYP450 Test: Principles, Challenges, and Future Clinical Utility in Digestive Disease

Keywords: ADR; adverse drug reaction; IBS-C; constipation-predominant irritable bowel syndrome; CYP450; cytochrome P450; IBS-D; diarrhea-predominant irritable bowel syndrome; EM; extensive metabolizer; GERD; gastroesophageal reflux disease; IBS; irritable bowel syn

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

The chlorinated AHR ligand 3,3′,4,4′,5-pentachlorobiphenyl (PCB126) promotes reactive oxygen species (ROS) production during embryonic development in the killifish (Fundulus heteroclitus)

Keywords: Non-invasive; PCB; CYP450; Development; In ovo EROD; In ovo ROS

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Characterisation of the xenobiotic-metabolizing Cytochrome P450 expression pattern in human lung tissue by immunochemical and activity determination

Keywords: Human lung; CYP450; Local metabolism; Enzyme expression; Interindividual variability

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Unifying mechanism for addiction and toxicity of abused drugs with application to dopamine and glutamate mediators: Electron transfer and reactive oxygen species

Keywords: ET; electron transfer; ROS; reactive oxygen species; OS; oxidative stress; DA; dopamine; Glu; glutamate; SO; superoxide; PN; peroxynitrite; NO; nitric oxide; DOPA; dihydroxyphenylalanine; CYP450; cytochrome P450; cAMP; cyclic adenosine monophosphate; AO;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Role of oxidative metabolites of cocaine in toxicity and addiction: oxidative stress and electron transfer

Keywords: CNS; central nervous system; ET; electron transfer; OS; oxidative stress; ROS; reactive oxygen species; SO; superoxide; PCP; phencyclidine; CYP450; cytochrome P450; NO; nitric oxide; GSH; glutathione; AO; antioxidant; MDA; malondialdehyde; RNS; reactive n

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Caffeine Metabolism, Genetics, and Perinatal Outcomes: A Review of Exposure Assessment Considerations during Pregnancy

Keywords: Caffeine; Cytochrome P450 1A2; CYP1A2; Genetic Polymorphisms; Pregnancy; Reproduction; Fetal Growth Retardation; Gestational Age; Spontaneous Abortion; AAMU; 5-acetyl-6-amino-3-methyluracil; AFMU; 5-acetylamino-6-formylamino-3-methyluracil; CYP1A2; cytoch

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Transport deficient (TR−) hyperbilirubinemic rats are resistant to acetaminophen hepatotoxicity

Keywords: TR−; transport deficient hyperbilirubinemic rats; Mrp; multidrug resistance-associated protein; APAP; acetaminophen; APAP-GSH; acetaminophen glutathione; APAP-GLUC; acetaminophen glucuronide; ICG; indocyanine green; NAPQI; N-acetyl-p-benzoquinoneimine;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Resistance to clopidogrel: A review of the evidence

Keywords: ACS; acute coronary syndromes; ADP; adenosine diphosphate; cAMP; cyclic adenosine monophosphate; CYP450; cytochrome P450; GPIIb/IIIa; glycoprotein IIb/IIIa; PCI; percutaneous coronary intervention; PGE1; prostaglandin E1; SAT; subacute stent thrombosis; V

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Molecular chemoprevention by selenium: A genomic approach

Keywords: APO-E; apolipoprotein-E; AOM; azoxymethane; AR; androgen receptor; CYP450; cytochrome p450; DHFR; dihydrofolate reductase; DMBA; 7,12-dimethylbenz[a]anthracene; EGR1; early growth response gene 1; ER; estrogen receptor; FABP; fatty acid binding protein; G

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

Heme oxygenase and the cardiovascular-renal system

Keywords: AA; arachidonic acid; Ang II; angiotensin II; ARF; acute renal failure; β-AR; β-adrenergic receptor; BP; blood pressure; cdk; cyclin-dependent kinases; CEC; circulating endothelial cell; cGMP; cyclic guanosine monophosphate; CKI; cyclin kinase inhibitor

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2005 سفارش ترجمه

Criteria for the safety evaluation of flavoring substances

Keywords: ABS; chromosomal aberration; ADH; alcohol dehydrogenase; ALD; aldehyde dehydrogenase; AE; anethole epoxide; CYP450; Cytochrome P450; CHO; Chinese hamster ovary; CoA; coenzyme A; CoE; Council of Europe; CCK; cholecystokinin; DDA; detailed dietary analysis;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2005 سفارش ترجمه