Keywords: T2DM; Type 2 diabetes mellitus; GBM pig; Guangxi Bama Mini-pig; STZ; streptozotocin; FBG; fasting blood glucose; FINS; fasting insulin; TG; triglyceride; TC; total cholesterol; IVGTT; intravenous glucose tolerance test; CYR61; Cystein rich 61 gene; RPL15;
مقالات ISI (ترجمه نشده)
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Keywords: Cyr61; cysteine-rich protein 61; RA; rheumatoid arthritis; IL-17; interleukin-17; ECM; extracellular matrix; CTGF; connective tissue growth factor; IGFBP; insulin-like growth factor binding protein domain; VWC; von Willebrand type C repeat; TSP-1; thrombo
Keywords: ADAMTS1; ADAM metallopeptidase with thrombospondin type 1 motif, 1; ATP; adenosine triphosphate; APP; amyloid beta precursor protein; ANGPT2; angiopoietin 2; Ara-C; arabinosylcytosine; GBA; beta-glucocerebrosidase; BDNF; brain derived neurotrophic factor;
miR-365 functions as a tumor suppressor by directly targeting CYR61 in osteosarcoma
Keywords: Osteosarcoma; miR-365; CYR61; Proliferation; Invasion;
Tumor necrosis factor-alpha suppresses the invasion of HTR-8/SVneo trophoblast cells through microRNA-145-5p-mediated downregulation of Cyr61
Keywords: Cyr61; Invasion; microRNA; Preeclampsia; TNF-α;
AICAR Antiproliferative Properties Involve the AMPK-Independent Activation of the Tumor Suppressors LATS 1 and 2
Keywords: AICAR; 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside; AMPK; adenosine monophosphate-activated protein kinase; CTGF; connective tissue growth factor (CCN2); CYR61; cysteine-rich angiogenic protein 61; HPRT; hypoxanthine-guanine phosphoribosyl transf
Skin and scale regeneration after mechanical damage in a teleost
Keywords: ECM; extracellular matrix; fn1a; fibronectin 1a; colIα1; collagen type I, alpha 1; colVα2; collagen type V, alpha 2; colXα1; collagen type X, alpha 1; ogn1; osteoglycin 1; ogn2; osteoglycin 2; crtac1a; cartilage acidic protein 1a; cyr61; cysteine-rich
COX-2 Forms Regulatory Loop with YAP to Promote Proliferation and Tumorigenesis of Hepatocellular Carcinoma Cells
Keywords: HCC; hepatocellular carcinoma; HB; hepatoblastoma; TEAD; TEA domain; CTGF; connective tissue growth factor; Cyr61; gene encoding cysteine rich 61; COX; cyclooxygenase; YAP; Yes-associated protein; PGE2; prostaglandin E2; VP; verteporfin; Cel; celecoxib; E
Inhibiting RHOA Signaling in Mice Increases Glucose Tolerance and Numbers of Enteroendocrine and Other Secretory Cells in the Intestine
Keywords: Mouse Model; Type 2 Diabetes; Enteroendocrine Cells; Signal Transduction; CCK; cholecystokinin; Ctgf; connective tissue growth factor; Cyr61; cysteine-rich angiogenic inducer 61; Dll1; delta-like protein 1; DBZ; dibenzazepine; EdU; 5-ethynyl-2â²-deoxyuri
MiR-93-5p promotes gastric cancer-cell progression via inactivation of the Hippo signaling pathway
Keywords: GC; Gastric cancer; FAT4; Protocadherin Fat 4; LATS2; Large tumor suppressors 2; CDX2; Caudal-related homeobox transcription factor; FOXM1; Fork head box M1; CTGF; Connective tissue growth factor; CYR61; Cysteine-rich angiogenic inducer 61; RUNX3; Runt-re
Investigation of the therapy targets of Yi-Qi-Yang-Yin-Hua-Tan-Qu-Yu recipe on type 2 diabetes by serum proteome labeled with iTRAQ
Keywords: T2DM; type 2 diabetes mellitus; IR; insulin resistance; HFD; high-fat diet; cAMP; cyclic adenosine monophosphate; cGMP; cyclic guanosine monophosphate; TG; triglyceride; TC; total cholesterol; TXB2; thromboxane B2; 6-keto PGF1α; 6-keto prostaglandin F1α
Connective tissue growth factor (CTGF) from basics to clinics
Keywords: AP1; activator protein 1; ASK1; apoptosis signal-regulating kinase 1; AT1R; angiotensin 2 type 1 receptor; AT2R; angiotensin 2 type 2 receptor; BCL-2; B-cell lymphoma 2; BMP4; bone morphogenic protein 4; BMP7; bone morphogenic protein 7; BMPs; bone morpho
High expression levels of Cyr61 and VEGF are associated with poor prognosis in osteosarcoma
Keywords: Cyr61; VEGF; Osteosarcoma; Prognostic indicator;
CYR61-An angiogenic biomarker to early predict the impaired healing in diaphyseal tibial fractures
Keywords: angiogenesis; biomarker; CYR61; fracture;
Dissection of mechanoresponse elements in promoter sites of the mechanoresponsive CYR61 gene
Keywords: CBP; CREB-binding protein; COX; cyclooxygenase; CREB; cyclic-AMP responsive element binding protein; CTGF; connective tissue growth factor; CYR61; cysteine-rich protein 61; Dexa; dexamethasone; EGR; early growth response; ERK; extracellular signal-regulat
Degradomic and yeast 2-hybrid inactive catalytic domain substrate trapping identifies new membrane-type 1 matrix metalloproteinase (MMP14) substrates: CCN3 (Nov) and CCN5 (WISP2)
Keywords: CTGF; connective tissue growth factor; Cyr61; cysteine-rich angiogenic inducer 61; Nov; nephroblastoma overexpressed; CCN; Cyr61/CTGF/Nov; CCN1; CCN5/WISP2; WNT1; inducible signalling pathway 2; CTCK; C-terminal cysteine-knot domain; ICAT; isotope-coded a
TEAD1 mediates the oncogenic activities of Hippo-YAP1 signaling in osteosarcoma
Keywords: Hippo; YAP; Osteosarcoma; PTGS2; CYR61;
Cyr61/CCN1 is involved in the pathogenesis of psoriasis vulgaris via promoting IL-8 production by keratinocytes in a JNK/NF-κB pathway
Keywords: Cyr61; Psoriasis vulgaris; IL-8; Keratinocyte; Pathogenesis; Neutrophils;
Impact of BRAF kinase inhibitors on the miRNomes and transcriptomes of melanoma cells
Keywords: ASNS; asparagine synthetase; AXL; proto-oncogene tyrosine kinase receptor AXL; BRAF; B-Raf proto-oncogene serine/threonine kinase/v-raf murine sarcoma viral oncogene homolog B; CCL2; chemokine C-C motif ligand 2; CE; coexpression coefficient; CHAC1; ChaC
Cardiac remodeling in Gαq and Gα11 knockout mice
Keywords: Gαq/Gα11-signaling; Cardiac tissue-remodeling; Matricellular proteins; Cyr61;
Atheroprotective laminar flow inhibits Hippo pathway effector YAP in endothelial cells
Keywords: CTGF; connective tissue growth factor; Cyr61; Cysteine-rich protein 61; DF; disturbed flow; EC; endothelial cells; LATS1/2; large tumor suppressor kinase 1/2; LF; laminar flow; YAP; Yes-associated protein;
cAMP-induced actin cytoskeleton remodelling inhibits MKL1-dependent expression of the chemotactic and pro-proliferative factor, CCN1
Keywords: CCN1; Cyr61; cAMP; 3â²-5â²-Cyclic adenosine monophosphate; MKL1; VSMC;
Mesenchymal stem/stromal cells as a pharmacological and therapeutic approach to accelerate angiogenesis
Keywords: AD-MSCs; adipose-derived mesenchymal stem cells; Ang-1; angiopoietin-1; BM; bone marrow; BM-MSC; bone marrow mesenchymal stem cell; CAM; chorioallantoic membrane; CM; conditioned medium; Cyr61; cysteine-rich, angiogenic inducer 61; EC; endothelial cell; E
Production of Cyr61 protein is modulated by extracellular acidification and PI3K/Akt signaling in prostate carcinoma PC-3 cells
Keywords: NAC; N-acetylcysteine; ECM; extracellular matrix; PI3K; phosphoinositide 3-kinase; SDS; sodium dodecyl sulfate; HRP; horseradish peroxidase; ECL; enhanced chemiluminescence; siRNA; small interfering RNA; PBS; phosphate buffered saline; Akt; serine/threoni
Caprin-1, a novel Cyr61-interacting protein, promotes osteosarcoma tumor growth and lung metastasis in mice
Keywords: Osteosarcoma; Metastasis; Cyr61; Caprin-1; Stress granules; Orthotopic mouse model;
Simvastatin Suppresses Osteoblastic Expression of Cyr61 and Progression of Apical Periodontitis through Enhancement of the Transcription Factor Forkhead/Winged Helix Box Protein O3a
Keywords: CCL2; chemotaxis; Cyr61; FoxO3a; induced periapical lesion; osteoblastic cells; simvastatin;
Snail promotes Cyr61 secretion to prime collective cell migration and form invasive tumor nests in squamous cell carcinoma
Keywords: Snail; Cyr61; Squamous cell carcinoma; EMT; Tumor invasion
NUR77 inhibits the expression of TIMP2 and increases the migration and invasion of HTR-8/SVneo cells induced by CYR61
Keywords: CYR61; NUR77; Trophoblast invasion; Preeclampsia;
Emerging nonanticoagulant role of low molecular weight heparins on extravillous trophoblast functions and on heparin binding-epidermal growth factor and cystein-rich angiogenic inducer 61 expression
Keywords: Extravillous trophoblast invasiveness; low molecular weight heparins; tinzaparin; enoxaparin; HB-EGF; Cyr61; MMP-2; AP-1;
Arecoline stimulated Cyr61 production in human gingival epithelial cells: Inhibition by lovastatin
Keywords: Arecoline; Cyr61; Lovastatin; Oral cancer
Expression of Cyr61 in primary salivary adenoid cystic carcinoma and its relation to Ki-67 and prognosis
Keywords: Salivary adenoid cystic carcinoma; Clinicopathological features; Cyr61; Ki-67; Prognosis;
Expression of cysteine-rich 61 is correlated with poor prognosis in patients with esophageal squamous cell carcinoma
Keywords: Cyr61; Esophageal squamous cell carcinoma; Biomarker; Prognosis
Suppression of human prostate cancer PC-3 cell growth by N-acetylcysteine involves over-expression of Cyr61
Keywords: NAC, N-acetylcysteine; PI3K, phosphoinositide 3-kinase; PC, prostate cancer; ROS, reactive oxygen species; CHX, cycloheximide; DCF-DA, 2′,7′-Dichlorofluorescin diacetate; ECL, enhanced chemiluminescenceN-acetylcysteine; Cyr61; Prostate cancers; ROS; Antio
Protective effects of Chlorella-derived peptide on UVB-induced production of MMP-1 and degradation of procollagen genes in human skin fibroblasts
Keywords: UVB; MMP-1; CYR61; Procollagen; TbRII; c-fos; c-jun; MCP-1; Skin fibroblasts; Chlorella
Radiation-induced modifications of the tumor microenvironment promote metastasis
Keywords: radiotherapy; angiogenesis; integrins; αVβ5; CYR61; TGF-β; tumor bed effect; invasion; metastasis;
Cell cycle regulated expression of NCoR might control cyclic expression of androgen responsive genes in an immortalized prostate cell line
Keywords: AR; androgen receptor; ARBS3.12AR; binding site on chromosome 3; ARE; androgen response element; CBP; calmoduline binding peptide; CDK4; cyclin dependent kinase 4; ChIP; chromatin immunoprecipitation; CYR61; cysteine-rich, angiogenic inducer, 61; DNA; deo
Major Histocompatibility Complex Class II Transactivator Inhibits Cysteine-rich 61 Expression in Osteoblastic Cells and Its Implication in the Pathogenesis of Periapical Lesions
Keywords: Apical periodontitis; bone resorption; CIITA; Cyr61; osteoblasts
Sclerostin binds and regulates the activity of cysteine-rich protein 61
Keywords: Sclerostin; Cyr61; CCN1; Osteoblasts; Osteoclasts; High bone mass; LRP5; Wnt
An Extract of Green Tea, Epigallocatechin-3-Gallate, Reduces Periapical Lesions by Inhibiting Cysteine-rich 61 Expression in Osteoblasts
Keywords: Cyr61; EGCG; human osteoblastic cells; periapical lesion
Simvastatin as a Novel Strategy To Alleviate Periapical Lesions
Keywords: Cyr61; human osteoblastic cells; periapical lesion; simvastatin
Cyr61, a member of ccn (connective tissue growth factor/cysteine-rich 61/nephroblastoma overexpressed) family, predicts survival of patients with endometrial cancer of endometrioid subtype
Keywords: Cyr61; Endometrial carcinoma; Immunohistochemistry; Survival; Prognostic factor
Transcriptome profiling and network pathway analysis of genes associated with invasive phenotype in oral cancer
Keywords: Oral cancer; Invasion mechanism; Cyr61; CD44; Network pathway
Molecular and preclinical models enhancing anti-tumour activity of zoledronic acid
Keywords: Aminobisphosphonates; Zoledronic acid; Clinical activity; Farnesyltransferase inhibitors; Prostate cancer; Breast cancer; Docetaxel; Cyr61; Microarray; Invasion;
Cyr61/CCN1 is a tumor suppressor in human hepatocellular carcinoma and involved in DNA damage response
Keywords: Cyr61; Hepatocellular carcinoma; Tumor suppressor; p53; Genotoxic stress
Bacteria induce CTGF and CYR61 expression in epithelial cells in a lysophosphatidic acid receptor-dependent manner
Keywords: CTGF; CYR61; Epithelial cells; Yersinia; LPA receptor; Bacteria–host interaction
The human Cyr61 gene is a transcriptional target of transforming growth factor beta in cancer cells
Keywords: TGFbeta; CCN; Cyr61; CTGF; Smad; promoter
Smad3 and Extracellular Signal-Regulated Kinase 1/2 Coordinately Mediate Transforming Growth Factor-β-Induced Expression of Connective Tissue Growth Factor in Human Fibroblasts
Keywords: connective tissue growth factor; cyr61; mitogen-activated protein kinase; Smad; TGF-β;