Keywords: حوزه مرگ; Death domain; Inflammasome; NALP3; PYD; ASC; ASC2; Molecular modeling; MD simulation; Docking;
مقالات ISI حوزه مرگ (ترجمه نشده)
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Keywords: حوزه مرگ; ANOVA; analysis of variance; Con; control; CPS; complex partial seizures; DD; death domain; EEG; electroencephalography; GFAP; glial fibrillary acidic protein; Iba1; ionized calcium-binding adaptor molecule 1; i.c.v.; intracerebroventricular; IL-1; interl
Keywords: حوزه مرگ; CARD; caspase recruitment domain; CC; coiled coil; DAMP; danger-associated molecular pattern; DD; death domain; DED; death effector domain; NBD; nucleotide-binding domain; NLR; nucleotide binding and oligomerization domain (NOD) leucine-rich repeat (LRR)-
Keywords: حوزه مرگ; Electrostatic stabilization; Cellular localization; Allostery; Caspase; Death domain; Context-dependent activities;
Keywords: حوزه مرگ; Lipid rafts; Signal transduction; IGF-I/PI3K/Akt signaling; Fas/CD95; CASMER; Cancer; APL; alkylphospholipid analogue; CASMER; cluster of apoptotic signaling molecule-enriched rafts; DED; death effector domain; DD; death domain; DISC; death-inducing signa
Overexpression of FADD and Caspase-8 inhibits proliferation and promotes apoptosis of human glioblastoma cells
Keywords: حوزه مرگ; GBM; glioblastoma; NC; negative control; FADD; fas Associated protein with Death Domain; HRP; horse radish peroxidase; OD; optical density; FCM; flow cytometry; qRT-PCR; quantitative real-time polymerase chain reaction; SD; standard deviation; DR5; death
Ontogeny and expression analysis of tube (interleukin-1 receptor-associated kinase-4 homolog) from Penaeus monodon in response to white spot syndrome virus infection and on exposure to ligands
Keywords: حوزه مرگ; ANOVA; analysis of variance; BLAST; basic local alignment search tool; DAMPS; damage-associated molecular patterns; DD; death domain; Dpi; days post infection; EFα; elongation factor α; EsTube; Eriocheir sinensis tube; hpi; hour post-infection; IRAK-4;
The functional domains for Baxâ2 aggregate-mediated caspase 8-dependent cell death
Keywords: حوزه مرگ; Bax; Baxâ2; Caspase 8; Apoptosis; Aggregation; Death domain;
The categorization and mutual modulation of expanded MyD88s in Crassostrea gigas
Keywords: حوزه مرگ; Crassostrea gigas; MyD88; Innate immunity; Death domain; TIR domain; NF-κB
The Paracaspase MALT1
Keywords: حوزه مرگ; NF-κB signaling; Protease; Caspase; Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1); ABC; activated B cell-like; ABC-DLBCL; activated B cell-like diffuse large B cell lymphoma; Ac; acetyl; ALL; acute lymphomblastic leukemia; AM
Targeting the Fas/FasL system in Rheumatoid Arthritis therapy: Promising or risky?
Keywords: حوزه مرگ; AP; activator protein; APAF; apoptosis protease activating factor; CAD; caspase-activated DNase; CHO; Chinese hamster ovary; CIA; collagen-induced arthritis; DD; death domain; DED; death effector domain; DISC; death-inducing signaling complex; DR; death r
The functions of the avian receptor activator of NF-κB ligand (RANKL) and its receptors, RANK and osteoprotegerin, are evolutionarily conserved
Keywords: حوزه مرگ; Aa; amino acids; APC; antigen presenting cells; BMDC; bone marrow-derived dendritic cells; BMM; BM-macrophages; Ca2+; calcium ions; CRD; cysteine rich domain; Ct; cycle threshold; DC; dendritic cells; DD; death domain; OPG; osteoprotegerin; PKC; protein k
Regulation of cell fate by lymphotoxin (LT) receptor signalling: Functional differences and similarities of the LT system to other TNF superfamily (TNFSF) members
Keywords: حوزه مرگ; Lymphotoxin; CD40; Apoptosis; Receptor cross-linking; Cell signalling; AP-1; activator protein-1; APRIL; a proliferation-inducing ligand; BAFF; B-cell activating factor belonging to the TNF family; CLL; chronic lymphocytic leukaemia; DD; death domain; DR;
Agonist antibody activates death receptor 6 downstream signaling involving TRADD recruitment
Keywords: حوزه مرگ; CRD; cysteine-rich domain; DD; death domain; DR; death receptor; FADD; Fas-associated death domain; JNK; c-Jun N-terminal kinase; N-APP; N-terminal β-amyloid precursor protein; siRNA; small interfering RNA; TNFR; tumor necrosis factor receptor; TRADD; TN
Functional assessment of the mutational effects of human IRAK4 and MyD88 genes
Keywords: حوزه مرگ; DD; death domain; HEK; human embryonic kidney; ID; internal domain; IRAK; Interleukin-1 receptor-associated kinase; MyD88; myeloid differentiating factor 88; Mal; MyD88 adaptor-like; NMR; nuclear magnetic resonance; ELISA; enzyme-linked immunosorbent assa
Neuroprotection of S-nitrosoglutathione against ischemic injury by down-regulating Fas S-nitrosylation and downstream signaling
Keywords: حوزه مرگ; 7-NI; 7-nitroindazole; DD; death domain; DED; death effector domain; DISC; death-inducing signaling complex; DTT; dithiothreitol; EDTA; ethylenediaminetetraacetic acid; EGTA; ethylene glycol tetraacetic acid; FADD; Fas-associated death domain; GSNO; S-nit
Molecular basis of the PED/PEA15 interaction with the C-terminal fragment of phospholipase D1 revealed by NMR spectroscopy
Keywords: حوزه مرگ; PED/PEA15; Phosphoprotein Enriched in Diabetes/Phosphoprotein Enriched in Astrocytes 15; DED; death effector domain; PLD1; phospholipase D1; PKC-α; protein kinase C-α isoform; ERK; extracellular signal-regulated kinase; HSQC; heteronuclear single quantu
The HECTD3 E3 Ubiquitin Ligase Suppresses Cisplatin-Induced Apoptosis via Stabilizing MALT1
Keywords: حوزه مرگ; CHX; cycloheximide; DD; death domain; DOC; destruction of cyclin; HECT; homologous to the E6-associated protein carboxyl terminus; HECTD3; HECT domain containing 3; IP; immunoprecipitation; MALT; mucosa-associated lymphoid tissue; SPR; surface plasmon res
The Brucella TIR-like protein TcpB interacts with the death domain of MyD88
Keywords: حوزه مرگ; Death domain; TIR domain; Protein interactions; Host–pathogen; Protein complementation assays
Large-scale RNAi screens add both clarity and complexity to Drosophila NF-κB signaling
Keywords: حوزه مرگ; RNAi; RNA interference; Dif; Dorsal-related immunity factor; AMP; antimicrobial peptide; imd; immune deficiency; JNK pathway; c-Jun N-terminal kinase pathway; Jak-STAT pathway; Janus kinase-Signal Transducer and Activator of Transcription pathway; dsR
Molecular identification and expression analysis of a novel tumor necrosis factor receptor from the black rockfish, Sebastes schlegelii
Keywords: حوزه مرگ; TNFR; TNFRSF6B; TNFRSF11B; Black rockfish; Death domain;
Molecular characterization and functional analysis of MyD88 in Chinese soft-shelled turtle Trionyx sinensis
Keywords: حوزه مرگ; Trionyx sinensis; MyD88; Death domain; TIR domain; NF-κB activity
Molecular cloning and characterisation of the rock bream, Oplegnathus fasciatus, Fas (CD95/APO-1), and its expression analysis in response to bacterial or viral infection
Keywords: حوزه مرگ; Rock bream; Fas; Death domain; Streptococcus iniae; RSIV
The NLRP12 Pyrin Domain: Structure, Dynamics, and Functional Insights
Keywords: حوزه مرگ; NLR proteins; death domain; pyrin domain; NLRP12; FAF-1HSQC, heteronuclear single quantum coherence; NOE, nuclear Overhauser enhancement; NLR, nucleotide-binding domain and leucine-rich repeat-containing receptor; DD, death domain; PYD, pyrin domain; FAF-
TRAIL and Interferon-α Act Synergistically to Induce Renal Cell Carcinoma Apoptosis
Keywords: حوزه مرگ; kidney; carcinoma, renal cell; TNF-related apoptosis-inducing ligand; interferons; extracellular signal-regulated MAP kinases; c-FLIP; cellular FLIP; cIAP; cellular inhibitor of apoptosis; DAPI; 4,6-diamidino-2-phenylindole; DcR; decoy receptor; DD; death
c-Cbl acts as a mediator of Src-induced activation of the PI3K-Akt signal transduction pathway during TRAIL treatment
Keywords: حوزه مرگ; c-Cbl; Casitas B-lineage lymphoma; DD; death domain; DISC; death-inducing signaling complex; DMEM; Dulbecco's modified Eagle's medium; DR4; TRAIL-R1; DR5; TRAIL-R2; DTT; dithiothreitol; EGF; epidermal growth factor; EGFR; EGF receptor; EGTA; ethylene glyc
Contribution of globular death domains and unstructured linkers to MyD88·IRAK-4 heterodimer formation: An explanation for the antagonistic activity of MyD88s
Keywords: حوزه مرگ; DD, death domain; IRAK, IL-1 receptor-associated kinase; TLR, Toll-like receptor; TIR, Toll–IL-1 receptorMyD88; IRAK; Death domain; Toll-like receptor; Monocytes/macrophages
S100A8/9 induces cell death via a novel, RAGE-independent pathway that involves selective release of Smac/DIABLO and Omi/HtrA2
Keywords: حوزه مرگ; ÎΨm; mitochondrial membrane potential; AIF; apoptosis-inducing factor; BH3; Bcl2 homology 3; BNIP3; Bcl2/adenovirus E1B 19 kD-interacting protein 3; DD; death domain; DED; death effector domain; DISC; death inducing signaling complex; Drp; dynamin-rela
TNFR1-induced NF-κB, but not ERK, p38MAPK or JNK activation, mediates TNF-induced ICAM-1 and VCAM-1 expression on endothelial cells
Keywords: حوزه مرگ; caspase; cysteine-aspartate-directed proteases; cPLA2; cytosolic phospholipase A2; DD; death domain; ERK; extracellular signal-regulated kinase; hr-GFP; humanised renilla green fluorescent protein; HUVEC; human umbilical endothelial cells; ICAM; intracell
The Edar subfamily in feather placode formation
Keywords: حوزه مرگ; TNFR; Placode; Feather; Skin; Evolution; Death domain; Edar; Troy; Xedar
Lethal activity of FADD death domain in renal tubular epithelial cells
Keywords: حوزه مرگ; apoptosis; death domain; FADD; kidney; NFκB; tubular cells
The p75NTR tumor suppressor induces cell cycle arrest facilitating caspase mediated apoptosis in prostate tumor cells
Keywords: حوزه مرگ; p75NTR; Death domain; NGF; Cell cycle suppression; Apoptosis; TUNEL staining
Upon intracellular processing, the C-terminal death domain-containing fragment of the p53-inducible PIDD/LRDD protein translocates to the nucleoli and interacts with nucleolin
Keywords: حوزه مرگ; PIDD; LRDD; Nucleolin; Death domain; Death filaments
Sensing and signaling during infection in Drosophila
Keywords: حوزه مرگ; DAP; diaminopimelic acid; DD; death domain; DREDD; death-related ced-3/Nedd2-like DD; FADD; Fas-associated DD-containing protein; GNBP; Gram-negative binding protein; IκB; inhibitory NF-κB; IKK; IκB kinase; JNK; Jun amino-terminal kinase; JAK; Janus fa
Prominent dominant negative effect of a mutant Fas molecule lacking death domain on cell-mediated induction of apoptosis
Keywords: حوزه مرگ; Fas; ALPS; Death domain; Dominant negative effect; DISC;
The expression of p75 neurotrophin receptor protects against the neurotoxicity of soluble oligomers of β-amyloid
Keywords: حوزه مرگ; Aβ; β-amyloid; AD; Alzheimer's disease; APP; β-amyloid precursor protein; DD; death domain; JICD; juxtamembrane domain; p75NTR; p75 neurotrophin receptor; PI3K; phosphatidylinositide 3-kinase; AO; acridine orange; EB; ethidium bromide; WT; wortmannin;
Regulatory roles and molecular signaling of TNF family members in osteoclasts
Keywords: حوزه مرگ; AP-1; activator protein-1; ASK1; apoptosis signal-regulated kinase-1; CARD; caspase recruiting domain; CFU-GM; colony forming unit-granulocyte/macrophage; CRD; cysteine-rich repeat; CTR; calcitonin receptor; DD; death domain; DED; death effector domain; E
Binding of Par-4 to the actin cytoskeleton is essential for Par-4/Dlk-mediated apoptosis
Keywords: حوزه مرگ; Par-4; prostate apoptosis response gene-4; DAP-kinase; death-associated protein kinase; Dlk; DAP like kinase; LZ; leucine zipper; DD; death domain; SAC; selective for apoptosis induction in cancer cells; GFP; green fluorescent protein; CytD; cytochalasin
Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotection for retinal degeneration
Keywords: حوزه مرگ; A2E; N-retinyl-N-retinylidene ethanolamine; AA; arachidonic acid; AAV; adeno-associated virus; ABCR; ATP-binding cassette transporter retina; AIF; apoptosis inducing factor; AMD; age-related macular degeneration; AP-1; activator protein-1; AP24; Mr 24; 00