Keywords: Deferiprone; Aluminum chloride; Immunotoxicity; Lymphocyte; Oxidative stress; Apoptosis;
مقالات ISI (ترجمه نشده)
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Keywords: DFP; deferiprone; HD; Huntington's disease; PD; Parkinson's disease; AD; Alzheimer's disease; TBARS; thiobarbituric acid-reactive substances; ABCB8; ATP binding cassette subfamily B member 8; ISC; iron-sulfur cluster; SDH; succinate dehydrogenase; LDH; la
Keywords: ACSL4; acyl-CoA synthetase long-chain family member 4; AD; Alzheimer's disease; ARE; antioxidant-responsive element; ANT; adenine nucleotide translocase; AP-1; activator protein-1; ATP; adenosine triphosphate; Bak; Bcl-2 antagonist/killer; BCEC; brain c
Keywords: Deferiprone; Cocrystal; Syntheses; Characterization; Dissolution
Keywords: Iron overload cardiomyopathy; Iron chelator; Deferoxamine; Deferiprone; Deferasirox; Antioxidant;
Keywords: Deferiprone; Solubility; Prediction; Jouyban-Acree model; van't Hoff equation; Cosolvency; Mixed solvent;
Keywords: Deferiprone; Iron chelation; Photolysis; Electron transfer; Free radical; Phototoxicity
Keywords: MDS; Myelodysplastic syndrome; Iron chelation; Iron overload; Transfusion-dependent; Deferasirox; Deferoxamine; Deferiprone
Keywords: Thalassemia major; Sickle cell disease; Iron overload; Iron chelation; Deferoxamine; Deferiprone; Deferasirox;
Keywords: Iron overload; Thalassemia; Sickle cell disease; Deferoxamine; Deferiprone; Deferasirox; Surcharge en fer; Thalassémie; Drépanocytose; Deferoxamine; Deferiprone; Deferasirox;
Keywords: DMSA; DMPS; Deferiprone; Deferasirox; Deferoxamine
From small deferiprone to macromolecular micelles: Self-assembly enhances iron chelation
Keywords: BLG; l-glutamic acid-5-benzyl ester; CMC; critical micelle concentrations; DCC; N,Nâ²-dicyclohexylcarbodiimide; DFP; deferiprone; DFO; desferoxamine; DFX; deferasirox; DMF; N-dimethylformamide; mPEG-PGlu; poly(ethylene glycol)-poly(glutamic acid); NCA; N
Investigation of deferiprone binding to different essential metal ions using microscale thermophoresis and electrospray ionization mass spectrometry
Keywords: Microscale thermophoresis; Mass spectrometry; Deferiprone; Essential metal ions; EC50; Hill coefficient;
Effects of the iron chelator deferiprone and the T-type calcium channel blocker efonidipine on cardiac function and Ca2+ regulation in iron-overloaded thalassemic mice
Keywords: ATP; adenosine triphosphate; [Ca2+]i; intracellular calcium; CICR; calcium-induced calcium release; DFP; deferiprone; EF; ejection fraction; EFO; efonidipine; FE; iron diet; FS; fraction shortening; HRV; heart rate variability; HT; β-thalassemic type; IC
Bone disease in β thalassemia patients: past, present and future perspectives
Keywords: AL; aledronate; BMD; bone mineral density; bw; body weight; BMD-L; lumbar spine bone mineral density; Ca; calcium supplementation; CLO; clodronate; COLIA1; collagen type I A1; D; vitamin D; DEXA; dual energy X-ray absorptiometry; DFO; desferrioxamine; DFP
Development of a new voltammetric sensor by using a hybrid material consisting of gold nanoparticles and S-organic compounds for detection of deferiprone-anti-thalassemia and anti HIV-1 drug
Keywords: Hybrid material; 3D-Self-assembled layer; Voltammetric drug sensing; Gold nanoparticle; Deferiprone;
To chelate or not to chelate in MDS: That is the question!
Keywords: Myelodysplastic syndromes; Transfusion; Iron chelation; Deferasirox; Deferoxamine; Deferiprone;
Iron accumulation and microglia activation contribute to substantia nigra hyperechogenicity in the 6-OHDA-induced rat model of Parkinson's disease
Keywords: Parkinson's disease; Transcranial sonography; Substantia nigra hyperechogenicity; 6-Hydroxydopamine; Deferiprone;
Deferiprone attenuates inflammation and myocardial fibrosis in diabetic cardiomyopathy rats
Keywords: Deferiprone; Diabetic cardiomyopathy; Fibrosis; Inflammatory;
Measurement and correlation of deferiprone solubility: Investigation of solubility parameter and application of van't Hoff equation and Jouyban-Acree model
Keywords: Solubility; Prediction; Deferiprone; Jouyban-Acree model; van't Hoff equation;
Iron distribution and histopathological study of the effects of deferoxamine and deferiprone in the kidneys of iron overloaded β-thalassemic mice
Keywords: Beta-knockout mice; Deferoxamine; Deferiprone; Kidney pathology; Iron overload;
Thermodynamic investigation on acid-base equilibria of deferiprone and deferasirox at different ionic strengths and various temperatures
Keywords: Deferiprone; Deferasirox; Protonation constant; Ionic strength; Temperature; Thermodynamic functions;
Efficient attenuation of Friedreich's ataxia (FRDA) cardiomyopathy by modulation of iron homeostasis-human induced pluripotent stem cell (hiPSC) as a drug screening platform for FRDA
Keywords: Friedreich's ataxia; Induced pluripotent stem cells; Cardiomyopathy; Idebenone; Deferiprone;
Hierarchical electrodeposition of methylene blue on ZnO nanocrystals thin films layered on SnO2/F electrode for in vitro sensing of anti-thalassemic drug
Keywords: Deferiprone; Zinc oxide nanocrystals; Methylene blue; Composites; Thalassemia; SnO2/F; Sensor;
A combination of an iron chelator with an antioxidant effectively diminishes the dendritic loss, tau-hyperphosphorylation, amyloids-β accumulation and brain mitochondrial dynamic disruption in rats with chronic iron-overload
Keywords: AD; Alzheimer's disease; APP; amyloid precursor protein; Aβ; amyloid-β; BBB; blood-brain barrier; DFO; deferoxamine; DFP; deferiprone; DFX; deferasirox; Drp1; dynamin-related protein 1; HFe; high-iron diet; Mfn2; mitofusin2; NAC; n-acetyl cysteine;
Retinal abnormalities in β-thalassemia major
Keywords: beta-thalassemia major; iron; iron overload; desferrioxamine retinopathy; deferiprone; hepcidin; pseudoxanthoma elasticum; PXE-like syndrome
Tacrine-(hydroxybenzoyl-pyridone) hybrids as potential multifunctional anti-Alzheimer's agents: AChE inhibition, antioxidant activity and metal chelating capacity
Keywords: Hydroxybenzoyl-pyridones; Tacrine; Anti-neurodegeneratives; Anti-AChE activity; Anti-oxidant activity; Metal chelation; Aβ; amyloid-β; ACh; acetylcholine; AChE; acetylcholinesterase; AChI; acetylthiocholine iodide; AD; Alzheimer's disease; BuChE; butyry
Prediction of deferiprone solubility in some non-aqueous binary solvent mixtures at various temperatures
Keywords: Deferiprone; Solubilization; Prediction; Jouyban-Acree model; van't Hoff equation; Cosolvency;
Inhibition of Fe2+- and Fe3+- induced hydroxyl radical production by the iron-chelating drug deferiprone
Keywords: EPR; Spin traps; Deferiprone; Iron chelation; Fenton reaction; Photo-Fenton reaction; Hydroxyl radical; Phototoxicity; Free radicals;
Electrochemical impediometric detection of anti-HIV drug taking gold nanorods as a sensing interface
Keywords: Deferiprone; Gold nanorods; Horse radish peroxidase; PGE electrode; Biosensor;
Deferiprone, a non-toxic reagent for determination of iron in samples via sequential injection analysis
Keywords: Deferiprone; Iron; Sequential injection
Novel aberrant genetic and epigenetic events in Friedreich׳s ataxia
Keywords: FRDA; Friedreich׳s ataxia; FXN; frataxin; ISC; iron-sulphur cluster; hPDL; human periodontal ligament; CASP3; active caspase-3; DNMT; DNA methyltransferase; CpG; cytosine phosphate group guanine; TSS; transcription start site; UP; upstream GAA repetiti
Comparative solution equilibrium studies on pentamethylcyclopentadienyl rhodium complexes of 2,2ʹ-bipyridine and ethylenediamine and their interaction with human serum albumin
Keywords: Cp*; pentamethylcyclopentadienyl; bpy; 2,2ʹ-bipyridine; DG; dansylglycine; dhp; 1,2-dimethyl-3-hydroxy-pyrid-4(1H)-one (deferiprone); DSS; 4,4-dimethyl-4-silapentane-1-sulfonic acid; en; ethylenediamine; HMM; high molecular mass; HSA; human serum albumin
Efficacy and safety of deferiprone for the treatment of pantothenate kinase-associated neurodegeneration (PKAN) and neurodegeneration with brain iron accumulation (NBIA): Results from a four years follow-up
Keywords: PKAN; NBIA; Iron; Deferiprone; Magnetic resonance imaging;
Thermodynamics of proton binding and weak (Cl−, Na+ and K+) species formation, and activity coefficients of 1,2-dimethyl-3-hydroxypyridin-4-one (deferiprone)
Keywords: Deferiprone; Medium effect; Solubility; Activity coefficients; Pitzer; Weak complexes
Multitargeted inhibition of hepatic fibrosis in chronic iron-overloaded mice by Salvia miltiorrhiza
Keywords: DFO; deferoxamine; DFP; deferiprone; ECM; extracellular matrix; GSH; glutathione; H&E; hematoxylin and eosin; HPLC-UV; high performance liquid chromatography-ultra violet; HSCs; hepatic stellate cells; Hyp; hydroxyproline; IL-1α; interleukin-1α; i.p
Long-term treatment with deferiprone enhances left ventricular ejection function when compared to deferoxamine in patients with thalassemia major
Keywords: Thalassemia major; Left ventricular ejection fraction (LVEF); Deferiprone; Deferoxamine; Echocardiography; Chelation
A comparative study of deferasirox and deferiprone in the treatment of iron overload in patients with myelodysplastic syndromes
Keywords: Deferiprone; Deferasirox, Chelation; Myelodysplasia; Toxicity; Side effects
Three most common nonsynonymous UGT1A6*2 polymorphisms (Thr181Ala, Arg184Serand Ser7Ala) and therapeutic response to deferiprone in β-thalassemia major patients
Keywords: ADRs, adverse drug reactions; UGTs, UDP-glucuronosyltransferases; PCR-RFLP, polymerase chain reaction–restriction fragment length polymorphism; WBC, white blood cell; PCM, paracetamolβ-Thalassemia; Deferiprone; Pharmacogenetics; UGT1A6*2 gene polymorphism
Hierro e infección fúngica invasiva
Keywords: Mucormicosis; Aspergilosis; Quelantes del hierro; Deferoxamina; Deferasirox; Deferiprona; Mucormycosis; Aspergillosis; Iron chelators; Deferoxamine; Deferasirox; Deferiprone;
Conjugation to 4-aminoquinoline improves the anti-trypanosomal activity of Deferiprone-type iron chelators
Keywords: Iron chelator; Anti-parasitic; Trypanosoma; Hybrid drugs; Deferiprone
When is iron overload deleterious, and when and how should iron chelation therapy be administered in myelodysplastic syndromes?
Keywords: iron; red blood cell transfusion [complications]; haemosiderosis; myelodysplastic syndromes; chelation therapy; deferasirox; deferoxamine; deferiprone
Surcharge en fer d'origine hématologique
Keywords: Surcharge en fer; Transfusion; Hémochromatose; Imagerie par résonance magnétique nucléaire; Chélation; Déférasirox; Défériprone; Post-transfusional iron overload; Transfusion; Iron loading anemia; Deferasirox; Deferiprone;
Systemic administration of the iron chelator deferiprone protects against light-induced photoreceptor degeneration in the mouse retina
Keywords: Deferiprone; Iron; Light damage; Retinal degeneration; Chelator
Management of thalassaemia
Keywords: anaemia; chelation; deferasirox; deferiprone; desferrioxamine; thalassaemia
Deferiprone modulates in vitro responses by peripheral blood T cells from control and relapsing-remitting multiple sclerosis subjects
Keywords: CD4 T cells; CD8 T cells; Regulatory T cells; T cell proliferation; Multiple sclerosis; Deferiprone;
Oral chelators in transfusion-dependent thalassemia major patients may prevent or reverse iron overload complications
Keywords: Thalassemia major; Combined chelation; Deferiprone; Deferasirox; Iron overload complications
Experience with Combination Therapy of Deferiprone and Desferrioxamine in β-Thalassemia Major Patients with Iron Overload at Maternity and Children Hospital, Al Madinah Al Munawarah, Saudi Arabia
Keywords: β-Thalassemia; Deferiprone; Desferrioxamine; iron overload
Iron Overload in Thalassemia and Related Conditions: Therapeutic Goals and Assessment of Response to Chelation Therapies
Keywords: Chelation; Iron; Deferiprone; Deferoxamine; Deferasirox; Thalassemia; Sickle;
Electrocatalytic oxidation of deferiprone and its determination on a carbon nanotube-modified glassy carbon electrode
Keywords: Carbon nanotube; Modified electrode; Deferiprone; Anti-thalassaemia drug; Electrocatalysis; HIV-1 replication inhibitor