Keywords: Cannabidiol; Antidepressant; Fluoxetine; Desipramine; Serotonin; Noradrenaline;
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Keywords: Desipramine; Fluoxetine; Mitochondria; Functional proteomics; Brain energy metabolism; 5-HT; 5-hydroxytryptamine; AD; Antidepressant Drugs; CBF; Cerebral Blood Flow; CCRS; NADH-cytochrome c Reductase Rotenone-Sensitive; CCRT; NADH-cytochrome c Reductase a
Keywords: Depression; Anxiety; Microdialysis; Norepinephrine release; Bed nucleus of the stria terminalis; Forced swimming test; RIS; repeated immobilization stress; CSD; chronic social defeat; CUS; chronic unpredictable stress; DMI; desipramine; NE; norepinephrine
Keywords: Mephedrone; Drug discrimination; Rimcazole; Desipramine; Fluoxetine; Cathinone; Bath salts; Mephedrone; (4-methylmethcathinone); PCP; (Phencyclidine); R-DOI; (2,5-Dimethoxy-4-iodoamphetamine); Î9-THC; (Î9-tetrahydrocannabinol); MDA; (3,4-Methylenedioxya
Keywords: Mesoporous silica nanoparticles; pH-sensitive; Desipramine; Polydopamine; Cancer nanotechnology
Keywords: 4EBP1; eukaryotic translation initiation factor 4E-binding protein 1; aCDase; acid ceramidase; Akt; Akt/protein kinase B; aSMase; acid sphingomyelinase; CalA; calyculin A; CAPP; ceramide activated protein phosphatase; CDase; ceramidase; Cer; ceramide; Des
Keywords: DA; dopamine; NE; norepinephrine; 6-OHDA; 6-hydroxydopamine; DMI; desipramine; PFC; prefrontal cortex; HPLC; high-performance liquid chromatography; Catecholamine; Medial prefrontal cortex; Body weight; Glucose preference;
Keywords: ANOVA; analysis of variance; BDNF; brain-derived neurotrophic factor; BrdU; 5-bromo-2â²-deoxyuridine; BSA; bovine serum albumin; Cdk-5; cyclin-dependent kinase-5; DAB; diaminobenzidine; DG; dentate gyrus; DMI; desipramine; FADD; Fas-associated protein wi
Keywords: Adrafinil; (PubChem CID: 3033226); Bupropion; (PubChem CID: 444); Cocaine; (PubChem CID: 656832); Desipramine; (PubChem CID: 65327); Methoxamine; (PubChem CID: 6081); Modafinil; (PubChem CID: 4236); Nifedipine; (PubChem CID: 4485); Noradrenaline; (PubChem
Keywords: Venlafaxine; Desipramine; Attention-deficit/hyperactivity disorder (ADHD); Noradrenaline; Dopamine; Mouse;
Keywords: Clonidine; Guanfacine; Propranolol; Prazosin; Desipramine; Yohimbine; Paranoid schizophrenia;
Keywords: ACTH; Adrenocorticotrophic hormone; DA; dopamine; DHBA; Dihydroxybenzylamine; DMI; desipramine; DOPAC; 3,4-Dihydroxyphenylacetic acid; EPM; Elevated plus maze; HPA; Hypothalamic-pituitary-adrenal; HPLC-EC; High performance liquid chromatography-el
Keywords: Desipramine; Open field; Natural killer cells; Response to novelty; Social position; Plasma cytokines;
Keywords: Desipramine; Almorexant; Orexin; Interaction; Pharmacokinetics; Pharmacodynamics;
Keywords: 5-HT; 5-Hydroxytryptamine or serotonin; AA-5-HT; N-arachidonoyl-serotonin; ACEA; arachidonoyl 2â²-chloroethylamide; AEA; N-arachidonoylethanolamine; 2-AG; 2-arachidonoylglycerol; AM251; N-(piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-
Male rats with same-sex preference show higher immobility in the forced swim test, but similar effects of fluoxetine and desipramine than males that prefer females
Keywords: FLX; fluoxetine; DMI; desipramine; FST; forced swim test; ATD; 1,4,6-androstatriene-3,17-dione; ADT; androst-4-ene-3,6,17-trione; LET; letrozole; SAL; saline; VEH; vehicle, corn oil; Rat sexual preference; Depression; FST; Fluoxetine; Desipramine;
Stimulatory effect of desipramine on lung metastases of adenocarcinoma MADB 106 in stress highly-sensitive and stress non-reactive rats
Keywords: Stress sensitivity; Metastasis; MADB 106 adenocarcinoma; Desipramine; Natural killer cell; Macrophage;
Desipramine increases cardiac parasympathetic activity via α2-adrenergic mechanism in rats
Keywords: Acetylcholine; Cardiac microdialysis; Desipramine; Rats; Yohimbine;
Desipramine rescues age-related phenotypes in depression-like rats induced by chronic mild stress
Keywords: Desipramine; Major depressive disorder; Aging; Oxidative damage; Telomerase activity;
Research articleThe hippocampus and dorsal raphe nucleus are key brain areas associated with the antidepressant effects of lithium augmentation of desipramine
Keywords: Depression; Antidepressant; Lithium; Desipramine; ÎFosB; FosB;
Prodepressant- and anxiogenic-like effects of serotonin-selective, but not noradrenaline-selective, antidepressant agents in mice lacking α2-containing GABAA receptors
Keywords: Gabra2; Fluoxetine; Desipramine; Anxiety; Behavioral despair;
Desipramine decreases expression of human and murine indoleamine-2,3-dioxygenases
Keywords: Desipramine; Kynurenine pathway; Ido1; Inflammation; Depression; PBMCs;
Ca2+ dependent surface trafficking of norepinephrine transporters depends on threonine 30 and Ca2+ calmodulin kinases
Keywords: AP; anterior-posterior; BAPTA/AM; 1,2-bis(2-aminophenoxy)ethane-N,N,Nâ²,Nâ²-tetraacetic acid tetrakis(acetoxymethyl ester); BIM; bisindolylmaleimide; Ca2+-free KRH; (Krebs-Ringer Bicarbonate), KRH without Ca2+ and with 0.2Â mM EGTA (ethylene glycol-bis(
Desipramine targets astrocytes to attenuate synaptic plasticity via modulation of the ephrinA3/EphA4 signalling
Keywords: Desipramine; astrocytes; Synaptic plasticity; ephrinA3/EphA4 signalling; ERK/MAPK; extracellular signal-regulated kinase/mitogen-activated protein kinase;
Role of TrkB in the anxiolytic-like and antidepressant-like effects of vagal nerve stimulation: Comparison with desipramine
Keywords: AD; antidepressant; ANOVA; analysis of variance; BDNF; brain-derived neurotrophic factor; BSA; bovine serum albumin; DMI; desipramine; DMSO; dimethyl sulfoxide; EDTA; ethylenediaminetetraacetic acid; FST; forced swim test; ICV; intracerebroventricular; IM
Prophylactic treatment with the tricyclic antidepressant desipramine prevents development of paclitaxel-induced neuropathic pain through activation of endogenous analgesic systems
Keywords: ANOVA; analysis of variance; CB1; cannabinoid receptor 1; CB2; cannabinoid receptor 2; CR; cremophor; DMI; desipramine; DMSO; dimethyl sulfoxide; DMEM; Dulbecco's Modified Eagle Medium; DRG; dorsal root ganglion; FBS; Fetal bovine serum; FDA; US Food an
Effect of desipramine on gene expression in the mouse frontal cortex – Microarray study
Keywords: Desipramine; Gene expression; Microarray; Mice
Astrocytic TNFα regulates the behavioral response to antidepressants
Keywords: Depression; Cytokine; TNFα; Fluoxetine; Desipramine; FST; TST;
Effect of antidepressant drugs on the vmPFC-limbic circuitry
Keywords: Desipramine; Fluoxetine; Ketamine; Nucleus accumbens; Depression; cFos;
Changes in blood CD4+T and CD8+T lymphocytes in stressed rats pretreated chronically with desipramine are more pronounced after chronic open field stress challenge
Keywords: Antidepressants; Desipramine; Open field stress; CD4+/CD8+T cell ratio; IFN-γ/IL-10 ratio; Rat
Life-long norepinephrine transporter (NET) knock-out leads to the increase in the NET mRNA in brain regions rich in norepinephrine terminals
Keywords: Norepinephrine transporter; Knock-out mice; Desipramine; Gene expression; Ago2 protein;
Rapid-acting antidepressant-like effects of acetyl-l-carnitine mediated by PI3K/AKT/BDNF/VGF signaling pathway in mice
Keywords: ACSF; artificial cerebrospinal fluid; ALC; acetyl-l-carnitine; BDNF; brain-derived neurotrophic factor; CNS; central nervous system; CUMS; chronic unpredictable mild stress; DMI; desipramine; FST; forced swimming test; HDACs; histone deacetylases; ICR; im
The effects of acute pharmacological stimulation of the 5-HT, NA and DA systems on the cognitive judgement bias of rats in the ambiguous-cue interpretation paradigm
Keywords: Rat; Cognitive bias; Ambiguous-cue; d-Amphetamine; Desipramine; Citalopram;
The tricyclic antidepressant desipramine inhibited the neurotoxic, kainate-induced [Ca2+]i increases in CA1 pyramidal cells in acute hippocampal slices
Keywords: Kainic acid; AMPA receptors; CA1 pyramidal cells; Rat hippocampal slices; [Ca2+]i; Desipramine
Brain monoamines and antidepressant-like responses in MRL/MpJ versus C57BL/6J mice
Keywords: C57BL/6J; MRL/MpJ; Citalopram; Desipramine; Tail suspension test; Serotonin; Norepinephrine; In vivo microdialysis; Hippocampus;
Electrochemical sensor for determination of desipramine in biological material
Keywords: Screen-printed electrode; Oral fluid; Simplex method; Desipramine
Crosstalk between contact hypersensitivity reaction and antidepressant drugs
Keywords: antidepressant drugs; contact hypersensitivity; cytokines; depression; desipramine; fluoxetine
Effect of tapentadol on neurons in the locus coeruleus
Keywords: Tapentadol; Opioid receptor; Alpha2-adrenoceptor; Locus coeruleus; Desipramine; Morphine
Inhibitory effect of antidepressants on B16F10 melanoma tumor growth
Keywords: antidepressants; fluoxetine; desipramine; mirtazapine; B16F10 melanoma; cytokines
Inhibition of 2,4-dinitrofluorobenzene-induced contact hypersensitivity reaction by antidepressant drugs
Keywords: antidepressant; contact hypersensitivity; DNFB; desipramine; fluoxetine; interleukin 10
Chronic antidepressant desipramine treatment increases open field-induced brain expression and spleen production of interleukin 10 in rats
Keywords: Desipramine; Open field; Interleukin 10; Natural killer cells; Response to novelty; Social position
GluN2B-containing NMDA receptors as possible targets for the neuroprotective and antidepressant effects of fluoxetine
Keywords: Neuroprotection; Depression; NMDA receptor subtypes; GluN2B subunit; Fluoxetine; Desipramine; Whole-cell patch-clamp
Magnesium deficiency induces anxiety and HPA axis dysregulation: Modulation by therapeutic drug treatment
Keywords: Magnesium; Anxiety; Stress axis; Selective serotonin re-uptake inhibitor; Diazepam; Corticotropin releasing hormone; ACTH; Desipramine;
The effects of isolated and enriched housing conditions on baseline and drug-induced behavioural responses in the male rat
Keywords: Elevated plus maze; Forced swim test; Homecage activity; Diazepam; Desipramine; AmphetamineEE, environmental enrichment; SC, standard conditions; IC, isolated conditions; EP, Melevated plus maze; FST, forced swim test; NA, noradrenaline; 5HT, serotonin; P
Noradrenergic antidepressant responses to desipramine in vivo are reciprocally regulated by arrestin3 and spinophilin
Keywords: α2 Adrenergic receptor; Arrestin; Depression; Desipramine; Forced swim test; Spinophilin5HT, serotonin; AR, adrenergic receptor; Arr, arrestin; DMI, desipramine; EPM, elevated plus maze; FLX, fluoxetine; FST, forced swim test; GPCR, G protein-coupled rece
Inhibitory effect of antidepressant drugs on contact hypersensitivity reaction
Keywords: contact hypersensitivity; desipramine; fluoxetine; interleukin 10;
Influence of chronic administration of antidepressant drugs on mRNA for galanin, galanin receptors, and tyrosine hydroxylase in catecholaminergic and serotonergic cell-body regions in rat brain
Keywords: Galanin; Norepinephrine; Locus coeruleus; Ventral tegmentum; Antidepressant; Desipramine; Paroxetine; Phenelzine
Morris water maze performance deficit produced by intermittent swim stress is partially mediated by norepinephrine
Keywords: Rat; Behavioral depression; Stress; Clonidine; Desipramine; Reboxetine; Morris water maze;
Analgesic antidepressants promote the responsiveness of locus coeruleus neurons to noxious stimulation: Implications for neuropathic pain
Keywords: Locus coeruleus; Neuropathic pain; Duloxetine; Desipramine; Noxious stimulation; Electrophysiology;
Synuclein modulation of monoamine transporters
Keywords: α-Syn; α-synuclein; β-Syn; β-synuclein; γ-Syn; γ-synuclein; AD; Alzheimer's disease; CNS; central nervous system; DA; dopamine; DAT; dopamine transporter; DMI; desipramine; MAT; presynaptic plasma membrane monoamine transporters; NAC; non-Aβ comp