دانلود مقالات ISI درباره Dhcr7 + ترجمه فارسی

اهمیت پس زمینه ژنتیکی سیگنالینگ اکسیسترول در سرطان

Importance of genetic background of oxysterol signaling in cancer

Keywords: Oxysterols; Cancer; Polymorphism; Risk; Genetics; Cholesterol; 25(OH)D; 25-hydroxyvitamin D; ABC; ATP-binding cassette; AEBS; antiestrogen-binding site; BC; breast cancer; BCR; biochemical recurrence; CETP; cholesteryl ester transfer protein; CH25H; chole

دانلود رایگان متن کامل مقاله ISI 115 صفحه سال انتشار : 2018 سفارش ترجمه

Propagation rate constants for the peroxidation of sterols on the biosynthetic pathway to cholesterol

Keywords: 7-DHC; 7-dehydrocholesterol; 8-DHC; 8-dehydrocholesterol; SLOS; Smith-Lemli-Opitz syndrome; CDPX2; X-linked dominant chondrodysplasia punctata; DHCR7; 7-dehydro-cholesterol reductase; MeOAMVN; 2,2′-azobis(4-methoxy-2,4-dimethylvaleronitrile); HPLC; high

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

تأثیر درمان دارویی روانگردان بر متابولیسم استرول

Effect of psychotropic drug treatment on sterol metabolism

Keywords: DHCR7; 7-dehydrocholesterol reductase; 7DHC; 7-dehydrocholesterol; SLOS; Smith-Lemli-Opitz syndrome; dhVitD; 1,25-dihydroxyvitamin D; 8DHC; 8-dehydrocholesterol; BHT; butylated hydroxytoluene; TPP; triphenylphosphine; PTAD; 4-phenyl-1,2,4-triazoline-3,5-d

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

پروب برای تزریق پروتئین به اختلالات بیوسنتز کلسترول: آلکینیل لانسترول به عنوان یک پیش ساز استرول زنده

Probes for protein adduction in cholesterol biosynthesis disorders: Alkynyl lanosterol as a viable sterol precursor

Keywords: 7-DHC; 7-dehydrocholesterol; Lath; lathosterol; Lan; lanosterol; Chol; cholesterol; SLOS; Smith-Lemli-Opitz syndrome; DHCR7; 7-dehydrocholesterol reductase; MS; mass spectrometry; APCI; atmospheric pressure chemical ionization; HPLC-; high pressure liquid

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

لیپید ها و فلوویروس ها، دیدگاه های کنونی و آینده برای کنترل بیماری های دنگی، زیکا و نیل غرب

Lipids and flaviviruses, present and future perspectives for the control of dengue, Zika, and West Nile viruses

Keywords: ACC; Acetyl-CoA carboxylase; BMP; bis(monoacylglycero)phosphate; BVDV; bovine viral diarrhea virus; CERS; ceramide synthase; CoA; Coenzyme A; COX-2; cyclooxygenase-2; DENV; dengue virus; DHCR7; 7-dehydrocholesterol reductase; dsRNA; double-stranded RNA; E

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2016 سفارش ترجمه

کلسترول در بیوگرافی میکولین و اختلالات هیپوومینینات

Cholesterol in myelin biogenesis and hypomyelinating disorders

Keywords: 7DHC; 7-dehydrocholesterol; ABC transporter; ATP binding cassette transporter; ApoA1; apolipoprotein A1; ApoE; apolipoprotein E; CNS; central nervous system; CYP46A1; cholesterol 24-hydroxylase; CYP51; lanosterol 14 alpha-demethylase; DHCR7; 7-dehydrochol

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

بر نقش پوست در تنظیم فعالیت های استروئیدوژنیک محلی و سیستمیک

On the role of skin in the regulation of local and systemic steroidogenic activities

Keywords: ABCA1; ATP binding cassette transporter A1; DHCR7; 3β-hydroxysterol Δ7-reductase; CRH; corticotropin releasing hormone; 7DHC; 7-dehydrocholesterol; 7DHP; 7-dehydropregnenolone; HPA; hypothalamic-pituitary-adrenal axis; GH; growth hormone; MC-R; mela

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

مکمل آنتی اکسیدان باعث کاهش نقایص مولکولی در سندرم اسمیت-لملی-اپیتس می شود

Antioxidant Supplementation Ameliorates Molecular Deficits in Smith-Lemli-Opitz Syndrome

Keywords: Antioxidants; 7-dehydrocholesterol; DHCEO; Dhcr7; oxysterol; Smith-Lemli-Opitz Syndrome

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

مدولاتورهای تغذیه ای اثربخشی استاتین در بیماری های قلبی عروقی و شناخت

Dietary modulators of statin efficacy in cardiovascular disease and cognition

Keywords: ABC; ATP binding cassette; ADR; adverse drug reactions; ALA; alpha-linolenic acid; ALT; alanine aminotransferase; CVD; cardiovascular disease; AUC; area under the concentration-time curve; Cmax; maximal plasma concentration; CYP; cytochrome P; EGCG; epi

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2014 سفارش ترجمه

کلسترول 5،6-اپوکسیدها: شیمی، بیوشیمی، سرنوشت متابولیک و سرطان

Cholesterol-5,6-epoxides: Chemistry, biochemistry, metabolic fate and cancer

Keywords: 5,6-Epoxy-cholesterol; Cholesterol oxide; Cholesterol epoxide; Dendrogenin; Cancer; AEBS; antiestrogen binding site; ChEH; cholesterol epoxide hydrolase; Tam, tamoxifen; trans-2-[4-(1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine; D8D7I; 3β-hydrox

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

5،6-اپوکسی کلسترول به داروهای ضد سرطان تاموکسیفن در سلولهای سرطان پستان کمک می کند

5,6-Epoxy-cholesterols contribute to the anticancer pharmacology of Tamoxifen in breast cancer cells

Keywords: AEBS; antiestrogen binding site; ChEH; cholesterol epoxide hydrolase; Tam; tamoxifen, trans-2-[4-(1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine; 4OH-tam; 4-[(Z)-1-[4-(2-dimethylaminoethyloxy)phenyl]-2-phenylbut-1-enyl]phenol; Ralox; raloxifene, [

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

مهندسی متابولیسم مخمر - هدف قرار دادن متابولیسم استرول و تشکیل ترپنوئید

Yeast metabolic engineering - Targeting sterol metabolism and terpenoid formation

Keywords: ABC; ATP-binding cassette; ADH; alcohol dehydrogenase; ADR; adrenodoxin reductase; ADX; adrenodoxin; ARE2; sterol acyltransferase; ARV1; mediator of sterol homeostasis; BTS1; GGPP synthase; CPR; cytochrome P450 reductase; CRT; carotenogenic (genes); CYP;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه

Dichlorophenyl piperazines, including a recently-approved atypical antipsychotic, are potent inhibitors of DHCR7, the last enzyme in cholesterol biosynthesis

Keywords: Antipyschotics; Teratogen; Cholesterol biosynthesis; Neurodevelopment; DHCR7; dehydrocholesterol reductase 7; DHCR24; dehydrocholesterol reductase 24; 7-DHC7; dehydrocholesterol; 8-DHC8; dehydrocholesterol; Des; desmosterol; Lan; lanosterol; Chol; cholest

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

The effect of age and gender on the genetic regulation of serum 25-hydroxyvitamin D - the FIN-D2D population-based study

Keywords: 25OHD; 25-hydroxyvitamin D; BMI; Body mass index; DBP; Vitamin D binding protein; DHCR7; 7-dehydrocholesterol reductase; GC; Group-specific component; NADSYN1; NAD synthetase 1; VDR; Vitamin D receptor; Vitamin D; 25-hydroxyvitamin D; Single nucleotide po

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Part A: Temporal and dose-dependent transcriptional responses in the liver of fathead minnows following short term exposure to the polycyclic aromatic hydrocarbon phenanthrene

Keywords: SREBF1; sterol regulatory element binding transcription factor 1; FASN; fatty acid synthase; HSD17B12; hydroxysteroid (17-beta) dehydrogenase 12; ACACA; acetyl-CoA carboxylase alpha; CYB5A; cytochrome b5 type A (microsomal); SLC27A4; solute carrier family

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Lysophosphatidylcholine induces expression of genes involved in cholesterol biosynthesis in THP-1 derived macrophages

Keywords: LPC; lysophosphatidylcholine; PCA; principal component analysis; FFA; free fatty acids; DMSO; dimethyl sulfoxide; FPKM; fragments per kilobase of transcript per million fragments mapped; RT-PCR; reverse transcription polymerase chain reaction; KEGG; Kyoto

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

The tumor-suppressor cholesterol metabolite, dendrogenin A, is a new class of LXR modulator activating lethal autophagy in cancers

Keywords: Dendrogenin A (PubChem CID: 9806490); Tamoxifen (PubChem CID: 2733526); Zymostenol (PubChem CID: 101770); 5,6α-Epoxycholesterol (PubChem CID: 227037); Histamine (PubChem CID: 774).; AEBS; antiestrogen binding site; ChEH; cholesterol-5,6-epoxide hydrolase

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

Chemistry, biochemistry, metabolic fate and mechanism of action of 6-oxo-cholestan-3β,5α-diol (OCDO), a tumor promoter and cholesterol metabolite

Keywords: Cholesterol; Oxysterol; Oncometabolism; Tumor promoter; Glucocorticoid receptor; Breast cancer; AEBS; antiestrogen binding site; ChEH; cholesterol epoxide hydrolase; Tam; Tamoxifen, trans-2-[4-(1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine; D8D7I

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Short communicationPhosphorylation regulates activity of 7-dehydrocholesterol reductase (DHCR7), a terminal enzyme of cholesterol synthesis

Keywords: 7DHC; 7-dehydrocholesterol; AMPK; AMP-activated protein kinase; CaMKII; calmodulin-dependent kinase II; CHO; Chinese hamster ovary; CKI; casein kinase I; DHCR7; 7-dehydrocholesterol reductase; HMGCR; 3-hydroxy-3-methylglutaryl-CoA reductase; PBGD; porphob

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

New insights into cellular cholesterol acquisition: promoter analysis of human HMGCR and SQLE, two key control enzymes in cholesterol synthesis

Keywords: ChIP-seq; chromatin immunoprecipitation-sequencing; DHCR7; 7-dehydrocholesterol reductase; DHCR24; 24-dehydrocholesterol reductase; EMSA; electrophoretic mobility shift assay; FCLPDS; fetal calf lipoprotein-deficient serum; FCS; fetal calf serum; HMGCR; 3

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Pleiotropic effects of antitumour alkylphospholipids on cholesterol transport and metabolism

Keywords: ABCA1; ATP-binding cassette transporter isoform A1; APL; alkylphospholipid; apoA1; apolipoprotein A1; CETP; cholesteryl ester transfer protein; CYP7A1; cholesterol 7α-hydroxylase; CYP27; sterol 27-hydroxylase; DHCR7; 7-dehydrocholesterol reductase; ER; e

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

HDL and microRNA therapeutics in cardiovascular disease

Keywords: ASO; antisense oligonucleotides; CAD; coronary artery disease; CVD; cardiovascular disease; DHCR7; 7-dehydrocholesterol reductase; HDL; high-density lipoproteins; HDL-C; HDL-cholesterol; HMGCS1; 3-hydroxy-3-methyl-glutaryl-CoA synthase 1; HMGCR; 3-hydroxy

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

DHCR7: A vital enzyme switch between cholesterol and vitamin D production

Keywords: 7DHC; 7-dehydrocholesterol; AEBS; antiestrogen binding site; DHCR7; 7-dehydrocholesterol reductase; DHCR14; Δ14-sterol reductase; DHCR24; 24-dehydrocholesterol reductase; EBP; emopamil binding protein; Hh; Hedgehog; HMGCR; 3-hydroxy-3-methylglutaryl-CoA

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2016 سفارش ترجمه

Oxysterols: From cholesterol metabolites to key mediators

Keywords: ABC; ATP-binding cassette; ACAT; acyl-coenzyme A cholesterol acyltransferase; C4; 7-hydroxycholestenone; CA; cholestanoic acid; CH25H; cholesterol-25-hydroxylase; ChEH; cholesterol epoxide hydrolase; CNS; central nervous system; CSF; cerebrospinal fluid;

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2016 سفارش ترجمه

A global transcriptional analysis of Megalobrama amblycephala revealing the molecular determinants of diet-induced hepatic steatosis

Keywords: Acads; acyl-CoA dehydrogenase; ALT; alanine aminotransferase; apoa1; apolipoprotein a1; Bdh1; 3-hydroxybutyrate dehydrogenase; COG; Cluster of Orthologous Groups; Cyp7a1; cytochrome p450 7a1; DGE; digital gene expression; Dhcr7; 7-dehydrocholesterol reduc

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

The sterol-based transcriptional control of human 7-dehydrocholesterol reductase (DHCR7): Evidence of a cooperative regulatory program in cholesterol synthesis

Keywords: 7DHC; 7-dehydrocholesterol; DHCR7; 7-dehydrocholesterol reductase; DHCR24; 24-dehydrocholesterol reductase; LDLR; low-density lipoprotein receptor; NF-Y; nuclear factor-Y; NPC1L1; Niemann-pick C1 like-1; SLOS; Smith-Lemli-Opitz Syndrome; Sp1; specific

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

A stable yeast strain efficiently producing cholesterol instead of ergosterol is functional for tryptophan uptake, but not weak organic acid resistance

Keywords: Cholesterol; Campesterol; Ergosterol; DHCR7; DHCR24; Yeast; Weak organic acid transport; Tryptophan transport; Membranes; Lipid engineering

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2011 سفارش ترجمه

Increasing cholesterol synthesis in 7-dehydrosterol reductase (DHCR7) deficient mouse models through gene transfer

Keywords: DHC, dehydrocholesterol; C, cholesterol; DHCR7, 7-dehydrocholesterol reductase; AAV, adeno-associated virus; BSTFA, N,O-bis[trimethylsilyl]trifluoroacetamide; TMS, trimethylsilylSmith–Lemli–Opitz syndrome (SLOS); DHCR7; AAV; Gene therapy

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Steroid production and excretion by the pregnant mouse, particularly in relation to pregnancies with fetuses deficient in Δ7-sterol reductase (Dhcr7), the enzyme associated with Smith–Lemli–Opitz syndrome

Keywords: SLOS; Smith–Lemli–Opitz syndrome; Mouse pregnancy steroids; GC/MS; DHCR7

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Cholesterol biosynthesis from birth to adulthood in a mouse model for 7-dehydrosterol reductase deficiency (Smith–Lemli–Opitz syndrome)

Keywords: SLOS; Cholesterol deficiency; Dehydrocholesterol; Mutant mouse model; Sterol metabolism; Dhcr7

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Inability to fully suppress sterol synthesis rates with exogenous sterol in embryonic and extraembyronic fetal tissues

Keywords: SLOS; Smith-Lemli-Opitz syndrome; DHCR7; 3β-hydroxysterol Δ7-reductase; HMGR; HMG-CoA reductase; SREBP; sterol regulatory element binding protein; SCAP; SREBP cleavage-activating protein; DPS; digitonin-precipitable sterols; Shh; Sonic hedgehog; Cho

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Residual cholesterol synthesis and simvastatin induction of cholesterol synthesis in Smith-Lemli-Opitz syndrome fibroblasts

Keywords: Smith-Lemli-Opitz syndrome; SLOS; 7-Dehydrocholesterol reductase; DHCR7; Cholesterol synthesis; Simvastatin;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه