دانلود مقالات ISI درباره Dhfr + ترجمه فارسی

Distinct haplotypes of dhfr and dhps among Plasmodium falciparum isolates in an area of high level of sulfadoxine–pyrimethamine (SP) resistance in eastern Sudan

Keywords: Dhfr; dhfr; dhps haplotypes; Pyrimethamine; Sulfadoxine resistance; Plasmodium falciparum; Evolution; Sudan

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Probing the roles of non-homologous insertions in the N-terminal domain of Plasmodium falciparum hydroxymethylpterin pyrophosphokinase-dihydropteroate synthase

Keywords: Dhfr; DHFR; dihydrofolate reductase; DHFS; dihydrofolate synthetase; DHPS; dihydropteroate synthase; HPPK; hydroxymethylpterin pyrophosphokinase; TS; thymidylate synthase; HMP; 6-hydroxymethylpterin; HMDP; 6-hydroxymethyl-7,8-dihydropterin; HMDPP; 6-hydroxymeth

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

The GroEL/GroES cis cavity as a passive anti-aggregation device

Keywords: Dhfr; DM-MBP; double mutant of maltose-binding protein; GSH/GSSG; reduced and oxidized glutathione, respectively; TG; trypsinogen; BSA; bovine serum albumin; NMR; nuclear magnetic resonance; DHFR; dihydrofolate reductase; GFP; green fluorescent protein; R. rubr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Spread and evolution of Plasmodium falciparum drug resistance

Keywords: Dhfr; Malaria; Drug resistance; pfcrt; dhfr; Evolution; Spread

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Catalytic and ligand-binding characteristics of Plasmodium falciparum serine hydroxymethyltransferase

Keywords: Dhfr; DHFR; dihydrofolate reductase; TS; thymidylate synthase; mTHF; 5,10-methylenetetrahydrofolate; THF; tetrahydrofolate; dUMP; 2′-deoxyuridine monophosphate; Malaria; Inhibitor; Enzyme; Kinetics; RNA binding;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

X-ray structure of the ternary MTX·NADPH complex of the anthrax dihydrofolate reductase: A pharmacophore for dual-site inhibitor design

Keywords: Dhfr; DHFR; dihydrofolate reductase; ba; Bacillus anthracis; ec; Escherichia coli; hs; Homo sapiens; MTX; methotrexate; p-ABA; para-aminobenzoic acid; NADPH; nicotinamide adenine dinucleotide phosphate (reduced form); DHF; dihydrofolate; IC50; inhibitor concent

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Methylenetetrahydrofolate reductase (MTHFR) C677T and thymidylate synthase promoter (TSER) polymorphisms in Indonesian children with and without leukemia

Keywords: Dhfr; ALL; acute lymphoblastic leukemia; CH2-THF; 5,10-methylenetetrahydrofolate; DDH; double distilled water; DHF; dihydrofolate; DHFR; dihydrofolate reductase; dTMP; deoxythymidine monophosphate; dTTP; deoxythymidine triphosphate; dUMP; deoxyuridine monophosp

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Short hairpin RNA targeted to dihydrofolate reductase enhances the immunoglobulin G expression in gene-amplified stable Chinese hamster ovary cells

Keywords: Dhfr; ShRna; Dhfr; IgG expression; CHO cells

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Expression, purification and characterization of recombinant mouse translation initiation factor eIF4E as a dihydrofolate reductase (DHFR) fusion protein

Keywords: Dhfr; Translational initiation factor; eIF4E; Fluorescence quenching; DHFR

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Dihydrofolate reductase I164L mutations in Plasmodium falciparum isolates: clinical outcome of 14 Kenyan adults infected with parasites harbouring the I164L mutation

Keywords: Dhfr; Malaria; Plasmodium falciparum; Drug resistance; Sulfadoxine-pyrimethamine; Mutation; DHFR;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Transcriptional regulation of aldo-keto reductase 1C1 in HT29 human colon cancer cells resistant to methotrexate: Role in the cell cycle and apoptosis

Keywords: Dhfr; AKR1C1, aldo-keto reductase 1 member C1; MTX, methotrexate; DHFR, dihydrofolate reductase; Sp1, specificity protein 1; APRT, adenine phosphoribosyltransferaseMethotrexate; AKR1C1; Transcriptional regulation; Sp1 binding; DHFR; Drug-resistance

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Variation and expression of dihydrofolate reductase (DHFR) in relation to spina bifida

Keywords: Dhfr; DHFR; Spina bifida; Real-time quantitative PCR;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Haloadaptation: Insights from comparative modeling studies of halophilic archaeal DHFRs

Keywords: Dhfr; DHFR; Extremophiles; Halophiles; Archaea; Homology (comparative) modeling; Haloadaptation

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Characterisation of exogenous folate transport in Plasmodium falciparum

Keywords: Dhfr; BCECF-AM; 2′,7′-bis-(2-carboxyethyl)-5,6-carboxylfluorescein acetoxymethyl ester; DHFR; dihydrofolate reductase; DHPS; dihydropteroate synthase; DNP; 2,4-dinitrophenol; pABA; p-aminobenzoic acid; MTX; methotrexate; NPP; new permeability pathway(s); PB

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

Discrete functional elements required for initiation activity of the Chinese hamster dihydrofolate reductase origin beta at ectopic chromosomal sites

Keywords: Dhfr; DNA replication; Origin; DHFR; Dinucleotide repeat; Transcription factor; Ori-beta

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

Negative selection using yeast cytosine deaminase/uracil phosphoribosyl transferase in Plasmodium falciparum for targeted gene deletion by double crossover recombination

Keywords: Dhfr; CD; cytosine deaminase; DHFR; dihydrofolate reductase; 5-FC; 5-fluorocytosine; FCU; chimeric gene of Saccharomyces cerevisiae CD and URPT; TK; thymidine kinase; URPT; uracil phosphoribosyl transferase; Malaria; Transfection; Negative selection; Gene knock

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2006 سفارش ترجمه

Defining the origin of Plasmodium falciparum resistant dhfr isolates in Senegal

Keywords: Dhfr; Plasmodium falciparum; Drug resistance; Senegal; Dhfr; Sulfadoxine–pyrimethamine

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Rapid selection of dhfr mutant allele in Plasmodium falciparum isolates after the introduction of sulfadoxine/pyrimethamine in combination with 4-aminoquinolines in Papua New Guinea

Keywords: Dhfr; Plasmodium falciparum; Chloroquine; Sulfadoxine/pyrimethamine; Resistance; Dhfr; Dhps; Combination therapy; Microsatellite

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Computer modelling of antifolate inhibition of folate metabolism using hybrid functional petri nets

Keywords: Dhfr; Folate metabolism; Purine; Pyrimidine; Enzyme inhibition; Antifolates; HFPN; hybrid functional petri nets; GON; genomic object net; DHF; dihydrofolate; THF; tetrahydrofolate; 5-CHO-THF; 5-formyl-THF; 5; 10-CH2-THF; 5; 10-methylene-THF; MTX; methotrexate;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Uniqueness of the mechanism of protein import into the peroxisome matrix: Transport of folded, co-factor-bound and oligomeric proteins by shuttling receptors

Keywords: Dhfr; AGT; alanine glyoxylate aminotransferase; BSA; bovine serum albumin; CAT; chloramphenicol acetyltransferase; DHFR; dihydrofolate reductase; ERAD; endoplasmic reticulum associated degradation; GFP; green fluorescent protein; HSA; human serum albumin; mPTS;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه

No evidence for a forced-unfolding mechanism during ATP/GroES binding to substrate-bound GroEL: no observable protection of metastable Rubisco intermediate or GroEL-bound Rubisco from tritium exchange

Keywords: Dhfr; DHFR; dihydrofolate reductase; FRET; fluorescence resonance energy tranfer; HX-MS; hydrogen exchange mass spectrometry; Rubisco; ribulose-1,5-bisphosphate carboxylase-oxygenase; GroEL; GroES; Rubisco; Tritium exchange; Metastable intermediate;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2005 سفارش ترجمه

Shikimate and folate pathways in the protozoan parasite, Perkinsus olseni

Keywords: Dhfr; DHPS; dihydropteorate synthase; DHFR; dihydrofolate reductase; EPSP; 5-enolpyruvyl shikimate 3-phosphate; PABA; p-aminobenzoate; Perkinsus olseni; Perkinsus atlanticus; Protozoan parasite; Shikimate pathway; Folate;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2005 سفارش ترجمه

Differential drug binding by the highly conserved Plasmodium falciparum thymidylate synthase

Keywords: Dhfr; DHFR; dihydrofolate reductase; TS; thymidylate synthase; mTHF; 5,10-methylenetetrahydrofolate; dUMP; 2′-deoxyuridine monophosphate; Malaria; Species-specific; Inhibitor; Enzyme; Conformation; Kinetics;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2005 سفارش ترجمه

Identification of a novel member of yeast mitochondrial Hsp70-associated motor and chaperone proteins that facilitates protein translocation across the inner membrane

Keywords: Dhfr; TOM; the translocase of the outer mitochondrial membrane; TIM; the translocase of the inner mitochondrial membrane; mtHsp70; mitochondrial Hsp70; MMC; mitochondrial Hsp70-associated motor and chaperone; FOA; fluoroorotic acid; PK; proteinase K; DHFR; mous

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2005 سفارش ترجمه

Selective chemical labeling of proteins in living cells

Keywords: Dhfr; ACP; acyl carrier protein; CoA; coenzyme A; DHFR; dihydrofolate reductase; EDT; 1,2-ethanedithiol; FlAsH; 4′,5′-bis(1,3,2-dithioarsolan-2-yl)fluorescein; GFP; green fluorescent protein; hAGT; human O6-alkylguanine-DNA alkyltransferase; Mtx; methotrexa

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Site-specific labeling of proteins with small molecules in live cells

Keywords: Dhfr; ACP; acyl carrier protein; DHFR; dihydrofolate reductase; GFP; green fluorescent protein; hAGT; human O6-alkylguanine transferase; Ni-NTA; nickel-nitrilotriacetic acid; PPtase; phosphopantetheine transferase;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

A new format of bispecific antibody: highly efficient heterodimerization, expression and tumor cell lysis

Keywords: Dhfr; BsAb; bispecific antibody; CH2 and CH3; constant region 2 and 3 of immunoglobulin heavy chain; DHFR; dihydrofolate reductase; ELISA; enzyme-linked immunosorbent assay; FCS; fetal calf serum; FITC; fluorescein isothiocyanate; Fv; variable fragment of antib

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Malaria in the Nuba Mountains of Sudan: baseline genotypic resistance and efficacy of the artesunate plus sulfadoxine-pyrimethamine and artesunate plus amodiaquine combinations

Keywords: Dhfr; Artesunate; Amodiaquine; Sulfadoxine-pyrimethamine; Pfcrt; Dhfr; Sudan;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Subunit complementation of thymidylate synthase in Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase

Keywords: Dhfr; Pf; Plasmodium falciparum; Lc; Lactobacillus casei; DHFR; dihydrofolate reductase; TS; thymidylate synthase; DHFR-TS; dihydrofolate reductase-thymidylate synthase; dUMP; deoxyuridine 5′-monophosphate; dTMP; deoxythymidine 5′-monophosphate; CH2H4folate

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

The relationship between folate transport activity at low pH and reduced folate carrier function in human Huh7 hepatoma cells

Keywords: Dhfr; 5-CHO-THF; 5-formyltetrahydrofolate; DHFR; dihydrofolate reductase; MTX; methotrexate; RFC; reduced folate carrier; PT523; Nα-(-4-amino-4-deoxypteroyl)-Nδ-hemiphthaloyl-1-ornithine; PT632; 5,8-dideaza analog of PT523; Folate transport; Folic acid; Metho

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Low tumor cell density environment yields survival advantage of tumor cells exposed to MTX in vitro

Keywords: Dhfr; DHFR; dihydrofolate reductase gene; FBS; fetal bovine serum; IC50; 50% inhibitory drug concentration; LCD; low cell density; MTX; methotrexate; NBMPR; nitrobenzyl-mercaptopurine ribonucleoside; DP; dipyridamole; SCD; standard cell density; Drug resistance

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Homocysteine and folate metabolism in depression

Keywords: Dhfr; BH4; tetrahydrobiopterin; BHMT; betaine-homocysteine methyltransferase; CBS; cystathionine-beta-synthetase; CNS; central nervous system; COMT; catechol methyl-transferease; DHFR; dihydrofolate reductase; HAM-D; Hamilton depression scale; Hcy; homocysteine

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Prevalence of pfcrt mutations in Congolese and Malawian Plasmodium falciparum isolates as determined by a new Taqman assay

Keywords: Dhfr; FAM; 6-carboxy-fluorescein; PCR; Polymerase chain reaction; MGB; minor groove binding non-fluorescent quencher; pfcrt; Plasmodium falciparum chloroquine resistance transporter; ASPCR; allele-specific PCR; DHPS; dihydropteroate synthase; DHFR; dihydrofolat

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

The anti-inflammatory action of methotrexate is not mediated by lymphocyte apoptosis, but by the suppression of activation and adhesion molecules

Keywords: Dhfr; MTX; methotrexate; PBMC; peripheral blood mononuclear cell; DHFR; dihydrofolate reductase; DPX; 1,3-dipropyl-8-phenylxanthine; DMPX; 3,7-dimethyl-1-propargylxanthine; DPCPX; 8-cyclopentyl-1,3-dipropylxanthine; CCPA; 2-chloro-N-cyclopentyladenosine; ICAM;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Entamoeba histolytica: Biochemical and molecular insights into the activities within microsomal fractions

Keywords: Dhfr; ALG; asparagine-linked glycosylation; AP; acid phosphatase; DPMS; dolichol-P-mannose synthase; ER; endoplasmic reticulum; Glc; glucose; GPI; glycosyl phosphatidylinositol; Man; mannose; β-NAcGase; β-N-acetyl-glucosaminidase; NAGPT; UDP-d-N-acetylglucosa

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Polymorphisms in Plasmodium falciparum dhfr and dhps genes and age related in vivo sulfadoxine-pyrimethamine resistance in malaria-infected patients from Nigeria

Keywords: Dhfr; Malaria; Plasmodium falciparum; dhfr; dhps; Sulfadoxine-pyrimethamine resistance; Nigeria;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

The origins and spread of antimalarial drug resistance: Lessons for policy makers

Keywords: Dhfr; Microsatellite; Drug resistance; Origins; pfcrt; dhfr; dhps; pfmdr; Plasmodium falciparum;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Molecular chemoprevention by selenium: A genomic approach

Keywords: Dhfr; APO-E; apolipoprotein-E; AOM; azoxymethane; AR; androgen receptor; CYP450; cytochrome p450; DHFR; dihydrofolate reductase; DMBA; 7,12-dimethylbenz[a]anthracene; EGR1; early growth response gene 1; ER; estrogen receptor; FABP; fatty acid binding protein; G

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

Transcription arrest at DNA damage sites

Keywords: Dhfr; T7 RNAP; T7 RNA polymerase; RNAPII; RNA polymerase II; GTFs; general transcription initiation factors; CPD; cyclobutane pyrimidine dimer; (6-4)PP; (6-4) photoproduct; cisplatin; diamminedichloroplatinum(II); cis-1,2-d(GG); cis-[Pt-(NH3)2{d(GpG)-N7(1),N7(2

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2005 سفارش ترجمه