دانلود مقالات ISI درباره حد تفکیک + ترجمه فارسی

Analysis of the substrate recognition state of TDP-43 to single-stranded DNA using fluorescence correlation spectroscopy

Keywords: حد تفکیک; Transactivation response DNA/RNA-binding protein 43 kDa; Dissociation constant; Binding stoichiometry; Fluorescence correlation spectroscopy; Electrophoretic mobility shift assay;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2018 سفارش ترجمه

Topography of human cytochrome b5/cytochrome b5 reductase interacting domain and redox alterations upon complex formation

Keywords: حد تفکیک; Cytochrome b5; Cb5; Cytochrome b5 reductase; Cb5R; Cytochrome c; Cyt c; Cytoglobin; Cyg; Ethylene diamine tetra acetic acid; EDTA; Flavin adenine dinucleotide; FAD; Heteronuclear single quantum coherence spectroscopy; HSQC; Isopropyl ß-D-1-thiogalactopyr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

A synergistic effect of phosphate, pH and Phe159 substitution on the formycin A association to the E. coli purine nucleoside phosphorylase

Keywords: حد تفکیک; Absorption; Association; Emission; Formycin A; E.coli purine nucleoside phosphorylase (PNPWT); E.coli PNP mutants; Asp; aspartic acid; Arg; arginine; E; efficiency of FRET; f; fractional intensity; FA; formycin A; FA−; formycin A anion; FRET; Fluorescen

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Nanobodies targeting cortactin proline rich, helical and actin binding regions downregulate invadopodium formation and matrix degradation in SCC-61 cancer cells

Keywords: حد تفکیک; Abl; ableson kinase; ABR; actin binding repeat; Arg; ableson related gene kinase; Arp2/3; actin related protein 2/3; ATAT1; alpha-tubulin N-acetyltransferase 1; DMEM; Dulbecco's modified Eagle's medium; DOX; doxycycline; Erk; extracellular signal-re

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Molecular and thyroid hormone binding properties of lamprey transthyretins: The role of an N-terminal histidine-rich segment in hormone binding with high affinity

Keywords: حد تفکیک; Transthyretin; Thyroid hormone; Zinc; 5-hydroxyisourate hydrolase; Lamprey; BSA; bovine serum albumin; CBB; Coomassie Brilliant Blue; EDTA; ethylenediaminetetraacetic acid; HIC; hydrophobic interaction column chromatography; HIU; 5-hydroxyisourate; HIUHas

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Extraction of information on macromolecular interactions from fluorescence micro-spectroscopy measurements in the presence and absence of FRET

Keywords: حد تفکیک; Fluorescence; Förster resonance energy transfer (FRET); Protein-protein interactions; Stoichiometry; Quaternary structure; Dissociation constant;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

Purification of equine IgG3 by lectin affinity and an interaction analysis via microscale thermophoresis

Keywords: حد تفکیک; Jacalin-Sepharose; Affinity chromatography; Equine IgG3; Dissociation constant;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

MS methods to study macromolecule-ligand interaction: Applications in drug discovery

Keywords: حد تفکیک; MS; mass spectrometry; IM-MS; ion mobility mass spectrometry; HR-MS; high resolution mass spectrometry; MS/MS; tandem mass spectrometry; ESI; electrospray ionization; NSI; nanoelectrospray ionization; MALDI; matrix assisted laser desorption ionization; FT

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Determination of pKa(s) of nilutamide through UV-visible spectroscopy

Keywords: حد تفکیک; Nilutamide; Dissociation constant; Spectrophotometry; pKa; Absorbance; UV-vis;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

Tea polyphenols enhance binding of porcine pancreatic α-amylase with starch granules but reduce catalytic activity

Keywords: حد تفکیک; Tea polyphenols; Enzyme binding; Starch granules; Dissociation constant; Binding rate;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Physico-chemical properties of the C70-l-lysine aqueous solutions

Keywords: حد تفکیک; Fullerene; l-Lysine; Refractometry; Specific conductivity; Molar conductivity; Dissociation constant; Excess thermodynamic functions; Viscosity;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Tricyclic antidepressants inhibit hippocampal α7* and α9α10 nicotinic acetylcholine receptors by different mechanisms

Keywords: حد تفکیک; AChR; nicotinic acetylcholine receptor; ACh; acetylcholine; TCAs; tricyclic antidepressants; α-BTx; α-bungarotoxin; MLA; methyllycaconitine; RT; room temperature; IC50; ligand concentration that produces 50% inhibition (of binding or of agonist activati

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Minimal physiologically-based pharmacokinetic model to investigate the effect of pH dependent FcRn affinity and the endothelial endocytosis on the pharmacokinetics of anti-VEGF humanized IgG1 antibody in cynomolgus monkey

Keywords: حد تفکیک; AIC; Akaike Information Criterion; ATA; anti-therapeutic antibody; AUC; area under the curve; CLe; antibody clearance in endothelial space; CDP; Complex Dedrick Plot; CV; coefficient of variations; FR; recycling fraction of IgG; F1; modulation factor of m

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

Quantitative and systems pharmacology 2. In silico polypharmacology of G protein-coupled receptor ligands via network-based approaches

Keywords: حد تفکیک; GPCR; G protein-coupled receptor; EP4; prostaglandin E2 receptor EP4 subtype; LPAR; lysophosphatidic acid receptor; DTI; drug-target interaction; ADE; adverse drug event; MoA; mechanism of action; Ki; inhibition constant; Kd; dissociation constant; IC50;

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

Neuroanatomical distribution and function of the vasopressin V1B receptor in the rat brain deciphered using specific fluorescent ligands

Keywords: حد تفکیک; ACTH; adrenocorticotropic hormone; AVP; arginine8 vasopressin; AC; adenylyl cyclase; BSA; bovine serum albumin; CaMKII; calmoduline-dependent serine/threonine kinase II; CHO; chinese hamster ovary; DG; dentate gyrus; DMEM; Dulbecco's modified Eagles'

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2018 سفارش ترجمه

Genetic variations in the DNA replication origins of human papillomavirus family correlate with their oncogenic potential

Keywords: حد تفکیک; HPV; human papillomavirus; BS1; E2 binding site 1; BS2; E2 binding site 2; BS3; E2 binding site 3; BS4; E2 binding site 4; C1; complex 1; C2; complex 2; C3; complex 3; EMSA; electrophoretic mobility shift assay; KD; dissociation constant; SNV; single nucl

دانلود رایگان متن کامل مقاله ISI 58 صفحه سال انتشار : 2018 سفارش ترجمه

Graphene- and CNTs-based carbocatalysts in persulfates activation: Material design and catalytic mechanisms

Keywords: حد تفکیک; Carbon nanotubes; Graphene; Peroxydisulfate; Peroxymonosulfate; Reaction pathways; AO7; acid orange 7; Eads; adsorption energy; AOPs; advanced oxidation processes; NH2-G; aminated graphene/NH2 functionalized graphene; BA; benzoic acid; BG; boron-doped gra

دانلود رایگان متن کامل مقاله ISI 121 صفحه سال انتشار : 2018 سفارش ترجمه

RP-HPLC determination of dissociation constant using solely aqueous mobile phase

Keywords: حد تفکیک; Dissociation constant; Reversed phase; HPLC; High-throughput measurement;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Binding of boronic acids with sugars in aqueous solution at physiological pH - Estimation of association and dissociation constants using spectroscopic method

Keywords: حد تفکیک; Boronic acid; Mono and disugars; Binding constant; Dissociation constant; Glucose level; Fluorescence intensity;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Development of a ssDNA aptamer for detection of residual benzylpenicillin

Keywords: حد تفکیک; Antibiotics; BenzylPenicillin; Aptamer; SELEX; rGO-SELEX; SELEX; systematic evolution of ligands by exponential enrichment; rGO; reduced graphene oxide; Kd; dissociation constant; LOD; limit of detection; MRL; maximum residue limit;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Ion mobility-mass spectrometry reveals evidence of specific complex formation between human histone deacetylase 8 and poly-r(C)-binding protein 1

Keywords: حد تفکیک; Protein-protein complex; Native mass spectrometry; Dissociation constant; Metalloenzymes; Carbonic anhydrase; Electrospray ionization;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

13C and 1H NMR measurements to investigate the kinetics and the mechanism of acetic acid (CH3CO2H) ionization as a model for organic acid dissociation dynamics for polymeric membrane water filtration

Keywords: حد تفکیک; Acetic acid; Nuclear magnetic resonance (NMR); Ionic formation; Ionic strength; Dissociation constant; NMR self-diffusion; Ionic pollutant; Nanofiltration;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Interactions between stepwise-eluted sub-fractions of fulvic acids and protons revealed by fluorescence titration combined with EEM-PARAFAC

Keywords: حد تفکیک; Binding; Functional groups; Fulvic-like components; Protein-like components; Dissociation constant;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Modulation effect of acidulated human serum albumin on Cu2 +-mediated amyloid β-protein aggregation and cytotoxicity under a mildly acidic condition

Keywords: حد تفکیک; Amyloid β-protein; Copper ion; Albumin; Negative charge; Mildly acidic condition; Aggregation; Aβ; amyloid β-proteins; AD; Alzheimer's disease; A-HSA; acidulated human serum albumin; ROS; reactive oxygen species; HSA; human serum albumin; ThT; thioflav

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

DNA aptamer identification and characterization for E. coli O157 detection using cell based SELEX method

Keywords: حد تفکیک; DNA aptamer; Cell SELEX; Dissociation constant;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis and preclinical evaluation of [11C]MA-PB-1 for in vivo imaging of brain monoacylglycerol lipase (MAGL)

Keywords: حد تفکیک; MAGL; [11C]MA-PB-1; MJN110; Biodistribution; PET imaging; AA; arachidonic acid; AEA; N-arachidonoyl ethanolamine; 2-AG; 2-arachidonoyl glycerol; BBB; blood brain barrier; Bmax; enzyme expression; BBr3; boron tribromide; CB1; cannabinoid 1 receptors; CDCl3

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Physico-chemical properties of the C60-l-lysine water solutions

Keywords: حد تفکیک; Fullerene; l-lysine; Solubility; Refractometry; Specific conductivity; Molar conductivity; Dissociation constant;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Screening of strong bicarbonate forming solvents for CO2 capture

Keywords: حد تفکیک; Screening; Bicarbonate forming solvent; CO2 capture; Dissociation constant;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Effect of PPAR-β/δ agonist GW0742 treatment in the acute phase response and blood-brain barrier permeability following brain injury

Keywords: حد تفکیک; APR; acute phase response; BBB; blood-brain barrier; CBF; cerebral blood flow; CCR; chemokine receptors; CNS; central nervous system; CXCL; chemokine (C-X-C motif) ligand; DAB; diaminobenzidine; EB; Evans Blue; GAPDH; glyceraldehyde 3-phosphate dehydrog

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2017 سفارش ترجمه

Selectivity of coronaridine congeners at nicotinic acetylcholine receptors and inhibitory activity on mouse medial habenula

Keywords: حد تفکیک; AChR; nicotinic acetylcholine receptor; ACh; acetylcholine; NCA; noncompetitive antagonist; RT; room temperature; MHb; medial habenula; VI; ventral inferior; Ki; inhibition constant; Kd; dissociation constant; IC50; ligand concentration that produces 50%

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Overview of experimental and computational methods for the determination of the pKa values of 5-fluorouracil, cyclophosphamide, ifosfamide, imatinib and methotrexate

Keywords: حد تفکیک; Dissociation constant; Anticancer drugs; Acid-base equilibrium; Experimental and computational methods; Cytostatic drugs;

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

Differential binding of monovalent cations to KcsA: Deciphering the mechanisms of potassium channel selectivity

Keywords: حد تفکیک; KcsA; potassium channel from Streptomyces lividans; DDM; dodecyl β-d-maltoside; SDS-PAGE; sodium dodecyl sulfate-polyacrylamide gel electrophoresis; tm; midpoint denaturation temperature (in degrees Celsius); ΔHo; enthalpy change upon protein unfolding

دانلود رایگان متن کامل مقاله ISI 62 صفحه سال انتشار : 2017 سفارش ترجمه

Binding studies of antimicrobial peptides to Escherichia coli cells

Keywords: حد تفکیک; Peptide; Antimicrobial; Cell; Binding; Temporin; Dissociation constant;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

The effect of pH on the glucose response of the glucose–galactose binding protein L255C labeled with Acrylodan

Keywords: حد تفکیک; Glucose-binding protein; pH effect; Fluorescence; Dissociation constant; Lifetime measurements; Biosensor

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

A class-A GPCR solubilized under high hydrostatic pressure retains its ligand binding ability

Keywords: حد تفکیک; G protein-coupled receptor; High hydrostatic pressure; Pheromone biosynthesis-activating neuropeptide receptor; Solubilization; Ligand binding ability; AEBSF; 4-(2-aminoethyl)benzensulfonyl fluoride; AP; ambient pressure; CBB; Coomassie Brilliant Blue; CH

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

The use of zeta potential to investigate the pKa of saturated fatty acids

Keywords: حد تفکیک; Dissociation constant; Saturated fatty acids; Isoelectric point; Surface pKa

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Solubility measurements of amoxicillin in mixtures of water and ethanol from 283.15 to 298.15 K

Keywords: حد تفکیک; Amoxicillin; Solubility; Enzymatic synthesis; Ethanol; Dissociation constant

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

NADP+ binding effects tryptophan accessibility, folding and stability of recombinant B. malayi G6PD

Keywords: حد تفکیک; ANS; 1-anilinonaphthalene-8-sulfonate; BmG6PD; Brugia malayi glucose-6-phosphate dehydrogenase; G6P; glucose 6-phosphate; GdmCl; guanidine hydrochloride; KI; potassium iodide; Brugia malayi G6PD; Dissociation constant; Homology model;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Bupropion and its photoreactive analog (±)-SADU-3-72 interact with luminal and non-luminal sites at human α4β2 nicotinic acetylcholine receptors

Keywords: حد تفکیک; Human α4β2 nicotinic acetylcholine receptor; Bupropion; (±)-SADU-3-72; Molecular docking; Luminal and non-luminal sites; Ca2+ influx; AChR; nicotinic acetylcholine receptor; NCA; noncompetitive antagonist; (±)-BP; (±)-bupropion [(±)-2-(tert-butylami

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

l-tryptophan and dipeptide derivatives for supercoiled plasmid DNA purification

Keywords: حد تفکیک; NMR; nuclear magnetic resonance; STD; Saturation Transfer Difference; HR-MAS; high resolution magic angle spinning; SPR; surface plasmon resonance; 5´-GMP; guanosine 5′-monophosphate; 3´-AMP; adenosine 5′-monophosphate; 5´-TMP; thymidine 5′-monop

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

The C-terminal region of the transcriptional regulator THAP11 forms a parallel coiled-coil domain involved in protein dimerization

Keywords: حد تفکیک; THAP; Thanatos-associated protein; HCF-1; host cell factor 1; HBM; HCF-1 binding motif; TEV; tobacco etch virus; LB; Luria-Bertani; IPTG; isopropyl-β-d-1-thiogalactopyranoside; IMAC; immobilized metal affinity chromatography; SEC; size exclusion chroma

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2016 سفارش ترجمه

Asparagine deamidation reduces DNA-binding affinity of the Drosophila melanogaster Scr homeodomain

Keywords: حد تفکیک; Asparagine deamidation; Dissociation constant; DNA binding; Hox transcription factor; Sex Combs Reduced; NMR spectroscopy;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Radiosynthesis and in vitro validation of 3H-NS14492 as a novel high affinity alpha7 nicotinic receptor radioligand

Keywords: حد تفکیک; Bmax; maximum density; 125I-BTX; 125I-α-bungarotoxin; Kd; dissociation constant; Ki; inhibition constant; NSB; non-specific binding; OD; optical density; PAM; positive allosteric modulator; SB; specific binding; TB; total binding; TE; tissue equivalent;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Fractionation of oil sands-process affected water using pH-dependent extractions: A study of dissociation constants for naphthenic acids species

Keywords: حد تفکیک; Oil sands process-affected water; Naphthenic acids; pH fractionation; Ultra-performance liquid chromatography time-of-flight mass spectrometry; Dissociation constant

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Determination of dissociation constant of some quinazoline derivatives at different temperatures in DMF-water medium

Keywords: حد تفکیک; Pyrazolo[5,1-b]quinazolines; Dissociation constant; Enthalpy; Gibb's energy; Half integral method; Average method;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Mercury (II) sensor based on monitoring dissociation rate of the trans-acting factor MerR from cis-element by surface plasmon resonance

Keywords: حد تفکیک; SPR; Metalloregulatory protein; Mercury; Dissociation constant; Promoter;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Dissecting the functional roles of the conserved NXXE and HXE motifs of the ADP-dependent glucokinase from Thermococcus litoralis

Keywords: حد تفکیک; ADP; adenosine-diphosphate; ATP; adenosine triphosphate; GK; glucokinase; TlGK; glucokinase from Thermococcus litoralis; glucose-6-P; glucose-6-phosphate; KM; Michaelis constant; kcat; turnover rate; Ki; inhibition constant; Ka; activation constant; KD; d

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Physico-chemical properties of the water-soluble C70-tris-malonic solutions

Keywords: حد تفکیک; Carboxylated fullerene; Solubility; Refractometry; Specific conductivity; Molar conductivity; Dissociation constant;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

A tyrosine-containing analog of mu-conotoxin GIIIA as ligand in the receptor binding assay for paralytic shellfish poisons

Keywords: حد تفکیک; Mu-conotoxin GIIIA; Paralytic shellfish poisoning; Receptor binding assay; Saxitoxin; μ1; skeletal muscle Na channel subtype; μ-CTX; μ-conotoxin; AOAC; Association of Official Analytical Communities, current official name is AOAC International; Bmax; m

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

In vitro selection and characterization of deoxyribonucleic acid aptamers against connective tissue growth factor

Keywords: حد تفکیک; Aptamer; Connective tissue growth factor; Systematic evolution of ligands by exponential enrichment; Deoxyribonucleic acid; Dissociation constant;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه