دانلود مقالات ISI درباره Dmap + ترجمه فارسی

شیمیدرمانی ضد مالاریا: کربناتهای دیمر و تری کربنات حاصل از آرتمیسینین

Antimalarial chemotherapy: Artemisinin-derived dimer carbonates and thiocarbonates

Keywords: SAR; structure-activity relationship; ACT; artemisinin combination therapy; HPLC; high performance liquid chromatography; DMAP; 4-dimethylaminopyridine; Py; pyridine; Antimalarial chemotherapy; Trioxane dimers; Single oral dose ACT; Oral bioavailability

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

بر اساس لیتیوم های کاتیونی گروه بنزوتیازول: سنتز و کاربرد برای تحویل ژن

Benzothiazole head group based cationic lipids: Synthesis and application for gene delivery

Keywords: Gene delivery; Cationic liposome; Lipoplexes; Reducible tocopherol-based cationic amphiphiles; Lipofection; DNA release; Lipofect; LipofectAmine-2000; DMEM; Dulbecco's modified Eagle's medium; DMAP; 4-(dimethylamino)pyridine; FBS; fetal bovine serum; PBS;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

مشتقات جدید تریپرپوئید لوپان باعث اختلال در میتوکندری سرطان پستان می شود و باعث مرگ سلول می شود

New derivatives of lupane triterpenoids disturb breast cancer mitochondria and induce cell death

Keywords: ADP; adenosine diphosphate; ATP; adenosine triphosphate; CsA; cyclosporin A; DMSO; dimethylsulfoxide; DMAP; dimethylaminopyridine; FCCP; carbonyl cyanide p-trifluoromethoxyphenylhydrazone; MPT; mitochondrial permeability transition; Log P; partition coef

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2014 سفارش ترجمه

مکانیزم کنترل نانوساختارهای فلزی در ماتریس های ساختار پلیمری از طریق راه حل های مبتنی بر مصنوعی استراتژی

Controlled accommodation of metal nanostructures within the matrices of polymer architectures through solution-based synthetic strategies

Keywords: 1D; one-dimensional; 2D; two-dimensional; ATRP; atom transfer radical polymerization; CS; chitosan; CT; X-ray computed tomography; CTAB; trimethylammonium bromide; DMAP; 4-dimethylaminopyridine; DMF; dimethylformamide; DNA; deoxyribonucleic acid; DT; dode

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2014 سفارش ترجمه

استراتژی تحویل فاکتورهای بیولوژیک از هیدروژل های پلیمری مهندسی برای درمان درمانی

Bioactive factor delivery strategies from engineered polymer hydrogels for therapeutic medicine

Keywords: GFs; growth factors; ALG; alginate; HA; hyaluronic acid; HEP; heparin; PEI; polyethyleneimine; PHEMA; poly(2-hydroxyethyl methacrylate); PEG; poly(ethylene glycol); PEO; poly(ethylene oxide); DEX; dextran; PPO; poly(propylene oxide); PPG; poly(propylene g

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2014 سفارش ترجمه

ساختار-فعالیت های مرتبط با اکسیکسال آمید ها را به عنوان بازدارنده هیدرولاز اپوکسی محلول در انسان جایگزین کرده است

Structure-activity relationships of substituted oxyoxalamides as inhibitors of the human soluble epoxide hydrolase

Keywords: EETs; epoxyeicosatrienoic acids; sEH; soluble epoxide hydrolase; EDCI; 1-[3-(dimethylamino)propyl]-3-ethyl-carbodiimide; DMAP; 4-dimethylaminopyridine; DMF; N,N-dimethylformamide; CMNPC; cyano-(2-methoxynaphthalen-6-yl)-methyl trans-(3-phenyl-oxyran-2-yl)

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2014 سفارش ترجمه

لیپوئید اسید هیالورونیک: سنتز و خواص فیزیکوشیمیایی

Hyaluronic acid lipoate: Synthesis and physicochemical properties

Keywords: BTH; bovine testicular hyaluronidase endo; CDI; 1,1′-carbonyldiimidazole; DMAc; N,N-dimethylacetamide; DMAP; 4-dimethylaminopyridine; DMSO; dimethyl sulphoxide; DOSY; diffusion ordered spectroscopy; DS; degree of substitution; FA; formamide; FTIR-ATR;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

متیلهای دی متیل آمینوپیریدین تریپرپوئید لوپان باعث اختلال میتوکندری می شوند و موجب انتقال گذار

Dimethylaminopyridine derivatives of lupane triterpenoids cause mitochondrial disruption and induce the permeability transition

Keywords: ΔΨm; mitochondrial transmembrane electric potential; BSA; bovine serum albumin; compound (1); 28-(4′-dimethylaminopyridinium-1′-acetoxy)-3β-hydroxylup-20(29)-ene chloride; compound (2); betulin 30-[4′-(dimethylamino) pyridinium-1′-yl]-3β,28-di

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

تداوم مایکل دیکمن / واکنش کلاسین ارتو-تلوات - حلال استونتون-وینبر

Tandem Michael-Dieckmann/Claisen reaction of ortho-toluates-the Staunton-Weinreb annulation

Keywords: Ac; acetyl; acac; acetylacetonate; 9-BBN; 9-borabicyclo[3.3.1]nonane; Bn; benzyl; Boc; tert-butyloxycarbonyl; BOM; benzyloxymethyl; brsm; based on recovered starting material; Bz; benzoyl; CAN; ammonium cerium(IV) nitrate; Cbz; benzyloxycarbonyl; CD; circ

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2013 سفارش ترجمه

DMAP catalysed vinylogous Rauhut-Currier reaction of allenoates with para-quinone methides

Keywords: Allenoate; DMAP; Zwitterion; p-Quinone methide; Vinylogous Rauhut-Currier reaction;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2018 سفارش ترجمه

N-acetylcysteine modified hyaluronic acid-paclitaxel conjugate for efficient oral chemotherapy through mucosal bioadhesion ability

Keywords: HA; hyaluronic acid; PTX; paclitaxel; NAC; N-acetylcysteine; DCC; dicyclohexylcarbodiimide; DMAP; 4-dimethylaminopyridine; DMF; N,N-dimethylformamide; NAC-HA-PTX; NAC modified HA-PTX; CMC; critical micelle concentration; C6; coumarin 6; DS; the degree of

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Structure-activity relationships of rationally designed AMACR 1A inhibitors

Keywords: α-Methylacyl-CoA racemase (AMACR, P504S); Drug lipophilicity; Enzyme inhibitors; Rational drug design; Structure-activity relationships; AMACR; α-methylacyl-CoA racemase; CDI; carbonyldiimidazole; DAST; (Diethylamino)sulfur trifluoride; DCC; Dicyclohexy

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

The evaluation of potent antitumor activities of shikonin coumarin-carboxylic acid, PMMB232 through HIF-1α-mediated apoptosis

Keywords: HIF-1α; hypoxia-inducible factor alpha 1; DMAP; 4 dimethyamino- pyridine; DCC; N, N' dicyclohexylcarbodiimide; DMEM; Dulbecco's modified Eagle's medium; MTT; 3-(4 5-dimethyl-2-thiazolyl)-2 5-diphenyl-2-H-tetrazolium bromide; IC50; Half of maximal i

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Design and synthesis of new potent N,N-bis(arylalkyl)piperazine derivatives as multidrug resistance (MDR) reversing agents

Keywords: MDR reversers; P-gp modulators; Piperazine derivatives; Chemosensitizers; Doxorubicin-resistant human erythroleukemia K562 cells (K562/DOX); Pirarubicin uptake; P-gp; P-glycoprotein; MRP1; Multidrug Resistance associated Protein 1; BCRP; Breast Cancer R

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Design and synthesis of aminoester heterodimers containing flavone or chromone moieties as modulators of P-glycoprotein-based multidrug resistance (MDR)

Keywords: P-gp; P-glycoprotein; SAR; Structure-activity relationships; DOX; Doxorubicin; EDCI; 1-(3-dimethylaminopropyl)-3-ethylcarbodiimmide hydrochloride; HOBt; 1-Hydroxybenzotriazole hydrate; DMAP; 4-dimethylaminopyridine; P-gp modulators; MDR reversers; Heterod

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Promoting effect of 4-dimethylaminopyridine on selective oxidation of benzyl alcohol over MoVTeNb mixed oxides

Keywords: Multicomponent vanadium-based metal oxides; Selective oxidation; DMAP; Nucleophilic assistance;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

Identification of an oxime-containing C-glucosylarene as a potential inhibitor of sodium-dependent glucose co-transporter 2

Keywords: Oxime; Sodium-dependent glucose co-transporter; Aryl C-glycosides; Diabetes management; Ac2O; acetic anhydride; AMG; α-methyl-d-glucopyranoside; BF3·OEt2; boron trifluoride etherate; CHO; Chinese hamster ovary; DMAP; 4-N,N-dimethylaminopyridine; hERG; h

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

New aziridine-based inhibitors of cathepsin L-like cysteine proteases with selectivity for the Leishmania cysteine protease LmCPB2.8

Keywords: Cysteine protease; Inhibitor; Aziridine; Rhodesain; Cruzain; Leishmania; DCC; Dicyclohexylcarbodiimide; DMAP; 4-(Dimethylamino)pyridine; DPSI; (S,S)-Diphenylsulfimine; GB/VI methodology; Generalized Born/Volume Integral methodology; LE; ligand efficiency;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

In vivo efficacy and pharmacokinetics of bi-aryl oxazolidinone RBx 11760 loaded polylactic acid-polyethylene glycol nanoparticles in mouse hematogenous bronchopneumonia and rat groin abscess caused by Staphylococcus aureus

Keywords: Nanoparticles; PLA-PEG; Oxazolidinone; Staphylococcus aureus; Antibacterial; Nanomedicine; ATCC; American type culture collection; ATR-FTIR; attenuated total reflectance-Fourier transforms infrared spectroscopy; ACN; acetonitrile; ADME; absorption, dist

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Design, synthesis and biological screening of 2-aminobenzamides as selective HDAC3 inhibitors with promising anticancer effects

Keywords: B16F10; murine melanoma cells; CDCl3; deuterated chloroform; CTCL; cutaneous T-cell lymphoma; DCM; dichloromethane; DFT; density functional theory; DMAP; 4-Dimethylaminopyridine; DMEM; Dulbecco's modified Eagle's media; DMF; dimethylformamide; DMSO; dimet

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2018 سفارش ترجمه

Peramivir conjugates as orally available agents against influenza H275Y mutant

Keywords: Peramivir; Caffeic acid; Conjugate; Neuraminidase; Inhibitor; Influenza; Drug resistance; Ala; alanine; All; allyl; Asn; asparagine; Asp; aspartic acid; CDI; 1,1′-carbonyl diimidazole; DIBAL-H; diisobutylaluminium hydride; DMAP; 4-dimethylaminopyridine;

دانلود رایگان متن کامل مقاله ISI 55 صفحه سال انتشار : 2018 سفارش ترجمه

Old meets new: Combination of PLA and RDRP to obtain sophisticated macromolecular architectures

Keywords: AGET; activator generated by electron transfer; AlpGP; 1,2:3,4-Di-O-isopropylidene-6-O-acryloyl-α-d-galactopyranose; ATRP; atom-transfer radical polymerization; BEMP; 2-tert-butylimino-2-diethylamino-1,3-dimethylperhydro-1,3,2-diazaphosphorine; BGMA; cis

دانلود رایگان متن کامل مقاله ISI 106 صفحه سال انتشار : 2018 سفارش ترجمه

Synthesis of hybrid materials using graft copolymerization on non-cellulosic polysaccharides via homogenous ATRP

Keywords: AAP; 4-aminoantipyrine; AGET; activators generated by electron transfer; AGP; agarose palmitate; AGU; anhydroglucose unit; AMIMB; 1-allyl-3-methylimidazolium bromide; AS; acetylated starch; Au NPs; gold nanoparticles; BIBA; α-bromoisobutyric acid; BIBB;

دانلود رایگان متن کامل مقاله ISI 125 صفحه سال انتشار : 2018 سفارش ترجمه

Discovery and evaluation of Cav3.1-selective T-type calcium channel blockers

Keywords: AcOH; acetic acid; 9-BBN; 9-borabicyclo(3.3.1)nonane; DAST; diethylaminosulfur trifluoride; DIPEA; N,N-diisopropylethylamine; DMAP; 4-(dimethylamino)pyridine; DMF; N,N-dimethylformamide; EDC·HCl; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochlorid

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

Aqueous microwave-assisted DMAP catalyzed synthesis of β-phosphonomalonates and 2-amino-4H-chromen-4-ylphosphonates via a domino Knoevenagel-phospha-Michael reaction

Keywords: DMAP; Microwave; Domino reaction; β-Phosphonomalonates; 2-Amino-4H-chromen-4-ylphosphonates; Aqueous condition;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery and evaluation of Cav3.2-selective T-type calcium channel blockers

Keywords: AcOH; acetic acid; Boc; tert-butylocycarbonyl; DIPEA; N,N-diisopropylethylamine; DMAP; 4-(dimethylamino)pyridine; DMF; N,N-dimethylformamide; EDC·HCl; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride; HOBt; hydroxybenzotriazole; KHMDS; potassi

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Simple determination of L-hydroxyproline in idiopathic pulmonary fibrosis lung tissues of rats using non-extractive high-performance liquid chromatography coupled with fluorescence detection after pre-column derivatization with novel synthetic 9-acetylimi

Keywords: AIC; 9-acetylimidazol-carbazole; DABSYL-Cl; dimethylaminoazobenzenesulfonyl chloride; DMAP; 4-dimethylaminopyridine; DMS-Cl; 4-(5,6-dimethoxy-2-phthalimidinyl)-2-methoxyphenylsulfonyl chloride; FMOC-Cl; fluorenylmethyl chloroformate; HPAEC-PAD; high perfo

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Investigation of epigallocatechin-3-O-caffeoate and epigallocatechin-3-O-p-coumaroate in tea leaves by LC/MS-MS analysis

Keywords: EGC derivative; Epigallocatechin-3-O-caffeoate; Epigallocatechin-3-O-p-coumaroate; Antioxidant activity; Tea; DMAP; N,N-dimethylaminopyridine; DPPH; 2,2-diphenyl-1-picrylhydrazyl; EDCI-HCl; 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide hydrochloride; EGC

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Cardioprotective effect of an exopolysaccharide from Lachnum YM130 and its derivatives on diabetic mice

Keywords: DM; diabetes mellitus; STZ; streptozotocin; SOD; superoxide dismutase; GPx; glutathione peroxidase; CAT; catalase; MDA; malondialdehyde; AGEs; advanced glycation end products; hs-CRP; high-sensitivity CRP; sICAM-1; intercellular adhesion molecule-1; NO; n

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis and evaluation of analogs of 5′-(((Z)-4-amino-2-butenyl)methylamino)-5′-deoxyadenosine (MDL 73811, or AbeAdo) - An inhibitor of S-adenosylmethionine decarboxylase with antitrypanosomal activity

Keywords: AdoMet; S-adenosyl-l-methionine; AdoMetDC; S-adenosylmethionine decarboxylase; BBB; bloodbrain barrier; Boc; tert-butoxycarbonyl; BSA; N,O-bis(trimethylsilyl)acetamide; CNS; central nervous system; DEAD; diethyl azodicarboxylate; DIAD; diisopropyl azodica

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis and energy transfer in original poly(3-alkylthiophene)-g-poly(fluorene) toothbrush copolymers

Keywords: Conjugated polymers; Block copolymers; Self-assembly; Fluorescence; Graft copolymers; CuAAC; (copper(I) catalyzed acetylene-azide cycloaddition); DCC; (N,N'-dicyclohexyl carbodiimide); DP; (degree of polymerization); DMAP; (N,N′-4-dimethylaminopyridin

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Coating lanthanide nanoparticles with carbohydrate ligands elicits affinity for HeLa and RAW264.7 cells, enhancing their photodamaging effect

Keywords: DIC; 1,3-diisopropylcarbodiimide; DIPEA; N,N-diisopropylethylamine; DLS; dynamic light scattering; DMAP; N,N-dimethyl-4-aminopyridine; DMF; N,N-dimethylformamide; DMEM; Dulbecco's Modified Eagle Medium; EPR effect; enhanced permeability and retention ef

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Conjugates of salicylaldoximes and peripheral site ligands: Novel efficient nonquaternary reactivators for nerve agent-inhibited acetylcholinesterase

Keywords: OP; organophosphate; hAChE; human acetylcholinesterase; ACh; acetylcholine; 2-PAM; pralidoxime; MINA; monoisonitrosoacetone; BBB; bloodbrain barrier; CNS; central nervous system; P-site; peripheral anionic site; PSL; peripheral site ligand; TIQ; tetrahydr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Environmental exposure to human carcinogens in teenagers and the association with DNA damage

Keywords: 8-OHdG; 8-hydroxydeoxyguanosine; CALUX; Chemical-Activated LUciferase gene eXpression; CI; confidence interval; DAP; dialkyl phosphate; 2; 5-DCP, 2,5-dichlorophenol; DDT; dichlorodiphenyltrichloroethane; DEAP; diethylalkyl phosphate; DEHP; di(2-ethylhexyl

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Dual 7-ethyl-10-hydroxycamptothecin conjugated phospholipid prodrug assembled liposomes with in vitro anticancer effects

Keywords: SN38; 7-ethyl-10-hydroxycamptothecin; CPT-11; irinotecan; TEM; transmission electron microscopy; cyro-TEM; cryogenic transmission electron microscopy; FDA; Food and Drug Administration; DDS; drug delivery system; EPR; enhanced permeability and retention;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis and in vitro evaluation of 5-substituted benzovesamicol analogs containing N-substituted amides as potential positron emission tomography tracers for the vesicular acetylcholine transporter

Keywords: ACh; acetylcholine; VAChT; vesicular acetylcholine transporter; PET; positron emission tomography; AD; Alzheimer's disease; PD; Parkinson's disease; vesamicol; (±)-trans-2-(4-phenylpiperidino)cyclohexanol; benzovesamicol; 3-(4-phenyl-piperidin-1-yl)-1,2,

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

2-Aminomethylthieno[3,2-d]pyrimidin-4(3H)-ones bearing 3-methylpyrazole hinge binding moiety: Highly potent, selective, and time-dependent inhibitors of Cdc7 kinase

Keywords: CPME; cyclopentyl methyl ether; DCM; dichloromethane; DMA; N,N-dimethylacetamide; DMAP; 4-dimethylaminopyridine; DME; 1,2-dimethoxyethane; DMF; N,N-dimethylformamide; DMSO; dimethyl sulfoxide; EDCI; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochlor

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

N-alkanol-N-cyclohexanol amine aryl esters: Multidrug resistance (MDR) reversing agents with high potency and efficacy

Keywords: MDR reversers; P-gp modulators; N-alkanol-N-cyclohexanol amine aryl esters; Chemosensitizers; Doxorubicin-resistant human erythroleukemia K562 cells (K562/DOX); Pirarubicin uptake; P-gp; P-glycoprotein; BCRP; Breast Cancer Resistance Protein; MRP1; Multi

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery of pentacyclic triterpene 3β-ester derivatives as a new class of cholesterol ester transfer protein inhibitors

Keywords: CETP inhibitor; Pentacyclic triterpenes; Non-HDL-C; Dyslipidemia; CVDs; cardiovascular diseases; CETP; cholesteryl ester transfer protein; HDL-C; high density lipoprotein-cholesterol; LDL-C; low density lipoprotein-cholesterol; VLDL; very-low-density lipo

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Oxadiazole-substituted naphtho[2,3-b]thiophene-4,9-diones as potent inhibitors of keratinocyte hyperproliferation. Structure−activity relationships of the tricyclic quinone skeleton and the oxadiazole substituent

Keywords: Antiproliferative activity; HaCaT cells; Quinone; Redox activation; Superoxide radical; 7-AAD; 7-aminoactinomycin D; CPR; NADPH-cytochrome P450 oxidoreductase; DCC; N,N'-dicyclohexylcarbodiimide; DHE; dihydroethidium; DMAP; 4-(dimethylamino)pyridine; DTPA

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery of orally bioavailable cyclohexanol-based NR2B-selective NMDA receptor antagonists with analgesic activity utilizing a scaffold hopping approach

Keywords: AcOEt; ethyl acetate; chloramine-T; N-chloro 4-methylbenzenesulfonamide sodium salt; DMAP; N,N-4-dimethylaminopyridine; DMF; N,N-dimethylformamide; hERG; human Ether-a-go-go Related Gene; HOBt; 1-hydroxybenzotriazole; IBX; o-iodoxybenzoic acid; LDA; lithi

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Studies of CDK 8/19 inhibitors: Discovery of novel and selective CDK8/19 dual inhibitors and elimination of their CYP3A4 time-dependent inhibition potential

Keywords: ADME; absorption, distribution, metabolism, and excretion; AML; acute myelogenous leukemia; AUC; area under the blood concentration time curve; b.i.d.; twice a day; CDK; Cyclin-dependent kinase; CLtotal; clearance; Cmax; maximum drug concentration; CRC; c

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

Improved synthesis and comparative analysis of the tool properties of new and existing D-ring modified (S)-blebbistatin analogs

Keywords: Blebbistatin; Myosin II; Photostability; Solubility; Cell membrane permeability; 2-mTHF; 2-methyltetrahydrofuran; A-B; apical-to-basolateral; B-A; basolateral-to-apical; CV; column volume; DMAP; 4-(dimethylamino)pyridine; DMEM; Dulbecco's modified Eagle m

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Cationic lipids bearing succinic-based, acyclic and macrocyclic hydrophobic domains: Synthetic studies and in vitro gene transfer

Keywords: Macrocyclic lipids; Cationic; Succinic; Lipoplex formulation; In vitro DNA transfer; pDNA; plasmid DNA; CHO-K1; Chinese hamster ovarian cells; DMA; dimethylamine; TMA; trimethylamine; DOPE; 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine; Chol; cholesterol

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2017 سفارش ترجمه

Anorexigenic effects induced by RVD-hemopressin(α) administration

Keywords: ACN; acetonitrile; AgRP; agouti related peptide; ARC; arcuate nucleus; BAT; brown adipose tissue; CART; cocaine and amphetamine-regulated transcript; CRH; corticotrophin releasing hormone; DA; dopamine; DCM; dichloromethane; DIPEA; N,N-Diisopropylethylami

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis of α,β-unsaturated aldehydes as potential substrates for bacterial luciferases

Keywords: DIBALH; diisobutylaluminum hydride; DMAP; 4-(dimethylamino)-pyridine; DMF; N,N-dimethylformamide; DCM; dichloromethane; THF; tetrahydrofuran; Bacterial bioluminescence; Luciferase; Molecular docking; α,β-unsaturated aldehydes;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis, experimental and theoretical characterizations of some new pyrrolo[2,3-d]pyrimidine derivatives bearing an aromatic sulfonamide moiety

Keywords: Pyrrolo[2,3-d]pyrimidine; DMAP; DFT; Tautomerism; Intramolecular proton transfer;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Stereoselective synthesis of modified cysteines

Keywords: Alloc; allyloxycarbonyl; Ar; aryl; Bn; benzyl; Cbz; benzyloxycarbonyl; Cbz-OSu; benzyloxycarbonylsuccinimide; NBS; N-bromosuccinimide; Boc; tert-butoxycarbonyl; m-CPBA; m-chloroperbenzoic acid; DABCO; 1,4-diazabicyclo[2.2.2]octane; DBU; 1,8-diazabicyclo[5

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis and in vitro evaluation of new fluorinated quinoline derivatives with high affinity for PDE5: Towards the development of new PET neuroimaging probes

Keywords: Quinoline; Fluorination; Phosphodiesterase 5; Radiotracer; Positron emission tomography; AD; alzheimer's disease; AllocCl; allyl chloroformate; ATR; attenuated total reflectance; cAMP; cyclic adenosine 3′,5′-monophosphate; cGMP; cyclic guanosine 3′,

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

Exploring the influence of indololactone structure on selectivity for binding to the C1 domains of PKCα, PKCε, and RasGRP

Keywords: BCl3; boron trichloride; CAN; ceric ammonium nitrate; DAG; diacylglycerol; DBU; 1,8-diazabicyclo[5.4.0]undec-7-ene; DMAP; 4-dimethylaminopyridine; GEFs; guanine nucleotide exchange factors; LiHMDS; lithium hexamethyldisilazide; MRCKs; myotonic dystrophy k

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه