دانلود مقالات ISI درباره Dmap + ترجمه فارسی

New bis(hydroxymethyl) alkanoate curcuminoid derivatives exhibit activity against triple-negative breast cancer in vitro and in vivo

Keywords: Antiproliferative agents; Antitumor agents; Bis(hydroxymethyl) alkanoate curcuminoids; Curcumin; Triple-negative breast cancer; BUN; blood urea nitrogen; DMAP; N,N-dimethylaminopyridine; DMF; dimethylformamide; DMSO; dimethylsulfoxide; EtOAc; ethyl acetat

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

Natural product-inspired esters and amides of ferulic and caffeic acid as dual inhibitors of HIV-1 reverse transcriptase

Keywords: Ocimum sanctum; HIV-1; RNase H; Reverse transcriptase; Triterpenes; Ferulic acid derivatives; AIDS; Acquired Immunodeficiency Syndrome; DCM; dichloromethane; DMAP; 4-dimethylaminopyridine; DP; DNA polymerase; DQF-COSY; Double Quantum Filtered-COrrelation

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis, characterization and molecular docking studies of substituted 4-coumarinylpyrano[2,3-c]pyrazole derivatives as potent antibacterial and anti-inflammatory agents

Keywords: DMAP; Pyrano[2,3-c]pyrazole; Pyranopyrazolo-pyrimidine; 3-Coumarinyl-3-pyrazolylpropanoic acids; C4C4 pyranone; Antibacterial; Anti-inflammatory; Molecular docking;

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2017 سفارش ترجمه

Structure−activity relationship study of novel 2-aminobenzofuran derivatives as P-glycoprotein inhibitors

Keywords: 2-Aminobenzofuran; Multidrug resistance; MDR; P-glycoprotein; P-gp; ABCB1; VVDIVTCFGFHMCM-UHFFFAOYSA-N; YISKRIBGSLFCKI-UHFFFAOYSA-N; JGWRKYGEHKPWNP-UHFFFAOYSA-N; XEHLQJGGWBPGQJ-UHFFFAOYSA-N; KXEXTQDMUJUNPJ-UHFFFAOYSA-N; LJOIMSPNCSVKOQ-UHFFFAOYSA-N; LRKBQV

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2017 سفارش ترجمه

Rare-earth metal complexes of β-diketiminato ligands bearing pendant nitrogen or oxygen donors

Keywords: Ln; rare-earth metal; Cp; cyclopentadienyl and cyclopentadienyl derivatives; THF; tetrahydrofuran; DMAP; 4-dimethylamino pyridine; Me; methyl; Et; ethyl; iPr; isopropyl; Bu; butyl; Ph; phenyl; Dipp; 2,6-diisopropylphenyl; Xyl; 2,6-dimethylphenyl; Mes*; 2,

دانلود رایگان متن کامل مقاله ISI 55 صفحه سال انتشار : 2017 سفارش ترجمه

Multidentate N-heterocyclic carbene complexes of the 3d metals: Synthesis, structure, reactivity and catalysis

Keywords: δ; Chemical shift; 1D; One dimension; 2D; Two dimensions; Ac; Acetate; Acac; Acetylacetonate; Ad; Adamantyl; Ar; Aryl; BARF; Tetrakis(3,5-di-trifluoromethylphenyl)borate); Bipy; 2,2′-bipyridine; Bu; Butyl; Bn; Benzyl; COD; Cyclooctadiene; COE; Cyclooct

دانلود رایگان متن کامل مقاله ISI 290 صفحه سال انتشار : 2017 سفارش ترجمه

4-Hydroxy-N-propyl-1,8-naphthalimide esters: New fluorescence-based assay for analysing lipase and esterase activity

Keywords: Carboxylester hydrolase; Enzyme assay; Fluorescence; Lipase; 1,8-Naphthalimide; BSA; bovine serum albumin; CalA; Candida antarctica lipase A; CalB; Candida antarctica lipase B; DMAP; 4-dimethylaminopyridine; DMSO; dimethyl sulfoxide; EDCI; 1-ethyl-3-(3-di

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

DMAP-based flexible polymer networks formed via Heck coupling as efficient heterogeneous organocatalysts

Keywords: Flexible polymer; Heterogeneous catalyst; Organocatalysis; Acylation; DMAP;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Novel internally quenched substrate of the trypsin-like subunit of 20S eukaryotic proteasome

Keywords: 20S Eukaryotic proteasome; Internally quenched peptides; Fluorescence; UPS; ubiquitin-proteasome system; ACC; 7-amino-4-carbamoylmethylcoumarin; AMC; 7-amino-4-methylocoumarin; FRET; fluorescent resonance energy transfer; ABZ; 2-aminobenzoic acid; Tyr(3

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

One-pot three component synthesis of 3,5-disubstituted 2,6-dicyanoaniline derivatives using 4-dimethylaminopyridine (DMAP) as a catalyst

Keywords: One-pot synthesis; β-Nitro-olefin; Aldehydes; Malononitrile; DMAP; 3,5-Disubstituted 2,6-dicyanoaniline;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

8-Halo-substituted naphtho[2,3-b]thiophene-4,9-diones as redox-active inhibitors of keratinocyte hyperproliferation with reduced membrane-damaging properties

Keywords: Antiproliferative activity; HaCaT cells; Naphtho[2,3-b]thiophene-4,9-diones; Quinone; Redox activation; Superoxide radical; CPR; NADPH-cytochrome P450 oxidoreductase; DCC; N,N′-dicyclohexylcarbodiimide; DHE; dihydroethidium; DMAP; 4-dimethylaminopyridin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Structural requirements of acylated Gly-l-Ala-d-Glu analogs for activation of the innate immune receptor NOD2

Keywords: Muramyl dipeptide; Immunomodulator; Desmuramylpeptide; NOD2 agonist; Immunostimulant; Immunoadjuvant; CARD; caspase activation and recruitment domain; DCC; dicyclohexylcarbodiimide; DMAP; 4-dimethylaminopyridine; EDC; 1-ethyl-3-(3-dimethylaminopropyl)carb

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Structure-activity relationships of 2-arylquinazolin-4-ones as highly selective and potent inhibitors of the tankyrases

Keywords: Tankyrase; PARP; 2-Arylquinazolin-4-one; Wnt; Hydrophobic cavity; ADP; adenosine diphosphate; Bn; benzyl; Cbz; benzyloxycarbonyl; DMAP; 4-dimethylaminopyridine; EDC; N′-ethyl-N-3-(dimethylaminopropyl)carbodiimide; ES; electrospray; HMBC; heteronuclear m

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

A thermo-responsive and photo-polymerizable chondroitin sulfate-based hydrogel for 3D printing applications

Keywords: bFGF; recombinant human Fibroblast Growth Factor-basic; CS; chondroitin sulfate; CS-TBA; CS in form of TBA salt; CSMA; methacrylated CS; CP; Cloud Point; DAPI; 4′,6-diamidino-2-phenylindole; DM; degree of methacrylation; DMAP; 4-(N,N-dimethylamino)pyrid

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

In vivo effective dibenzo[b,d]furan-1-yl-thiazoles as novel PDE-4 inhibitors

Keywords: PDE; phosphodiesterase; TNF-α; tumour necrosis factor; nm; nanomolar; IL; interleukin; μM; micromolar; @; at; PBMC; peripheral blood mononuclear cells; LPS; lipopolysaccharides; COPD; chronic obstructive pulmonary disease; CC; column chromatography; HCl

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Recent advances in η2-disilene and η2-disilyne mononuclear transition metal complexes and related compounds

Keywords: 2-Ad; 2-adamantylidene; cod; 1,5-cyclooctadiene; Cp; η5-cyclopentadienyl; Cp*; η5-pentamethylcyclopentadienyl; Cy; cyclohexyl; dcpe; 1,2-bis(dicyclohexylphosphino)ethane; DCD; Dewar-Chatt-Duncanson; DFT; density functional theory; DMAP; 4-(dimethyla

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

Development, synthesis and structure-activity-relationships of inhibitors of the macrophage infectivity potentiator (Mip) proteins of Legionella pneumophila and Burkholderia pseudomallei

Keywords: Mip; macrophage infectivity potentiator; PPIase; peptidyl-prolyl cis/trans isomerase; LpMip; L. pneumophila Mip; BpMip; B. pseudomallei Mip; SAR; structure-activity relationship; HSQC; Heteronuclear Single Quantum Coherence; NMM; N-methylmorpholine; DIP

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2016 سفارش ترجمه

Achievement of regioselectivity in transition metal-catalyzed direct C-H (hetero)arylation reactions of heteroarenes with one heteroatom through the use of removable protecting/blocking substituents or traceless directing groups

Keywords: Chemoselectivity; Regioselectivity; Direct C-H (hetero)arylation; Transition metal catalysts; Removable groups; Traceless directing groups; Deprotection; Ac; acetyl; acac; acetylacetonate; 1-Ad; 1-adamantyl; AIBN; azobisisobutyronitrile; Ar; aryl; Boc;

دانلود رایگان متن کامل مقاله ISI 62 صفحه سال انتشار : 2016 سفارش ترجمه

Biaryl thioether synthesis via CuI catalyzed dominothiolation of aryl halides in the presence of DMAP as ligand

Keywords: DMAP; CuI; C-S coupling; Aryl halide; Thiourea;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2015 سفارش ترجمه

α,β-Unsaturated aldehyde of hyaluronan-Synthesis, analysis and applications

Keywords: 3T3; standard fibroblast cell line; COSY; correlation spectroscopy; DMAP; 4-dimethylaminopyridine; DOSY; diffusion ordered spectroscopy; DS; degree of substitution; FTIR; Fourier transform infrared spectroscopy; HA; hyaluronan; h; hour; HSQC; heteronuclea

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Cyclen-based double-tailed lipids for DNA delivery: Synthesis and the effect of linking group structures

Keywords: Boc; tert-butoxycarbonyl; cyclen; 1, 4, 7, 10-tetraazacyclododecane; lipoplexes; liposome/DNA complexes; TE; gene transfection efficiency; EDC HCl; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride; HOBt; 1-hydroxybenzotriazole; TFA; trifluoroac

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Structure-activity relationship study using peptide arrays to optimize Api137 for an increased antimicrobial activity against Pseudomonas aeruginosa

Keywords: Apidaecin; Gram-negative bacterium; Proline-rich antimicrobial peptide (PrAMP); Pseudomonas aeruginosa; SPOT synthesis; AMP; antimicrobial peptide; DIC; N,N′-diisopropylcarbodiimide; DIPEA; N-ethyldiisopropylamine; DMAP; 4-dimethylaminopyridine; gu; N,N

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Synthesis of photoreactive ivermectin B1a derivatives and their actions on Haemonchus and Bombyx glutamate-gated chloride channels

Keywords: AVM; avermectin; DCC; dicyclohexylcarbodiimide; DIPEA; N,N-diisopropylethylamine; DMAP; 4-(dimethylamino)pyridine; DMF; N,N-dimethylformamide; DMSO; dimethyl sulfoxide; EDC; 1-ethyl-3-(3-dimethylamino-propyl)carbodiimide; GABA; γ-aminobutyric acid; GABAC

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Synthesis, biological evaluation and docking analysis of a new series of methylsulfonyl and sulfamoyl acetamides and ethyl acetates as potent COX-2 inhibitors

Keywords: AA; arachidonic acid; CMC; carboxymethylcellulose; COX; cyclooxygenase; Coxibs; COX-2 selective inhibitors; Das; accuracies percentages; DIPA; diisopropylamine; DMAP; dimethylaminopyridine; EDCI; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide; EIA; enzyme

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Phylloxera (Daktulosphaira vitifoliae Fitch) alters the carbohydrate metabolism in root galls to allowing the compatible interaction with grapevine (Vitis ssp.) roots

Keywords: ATP; adenosin-triphosphate; BLAST; basic local alignment search tool; BLAT; BLAST-like alignment tool; BSTFA; N,O-bis(trimethylsilyl)trifluoroacetamide; CFDA; carboxyfluorescein diacetate; DFCI; Dana Farber Cancer Institute; DMAP; 4-dimethylaminopyridine;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Synthesis, molecular modeling, and biological evaluation of novel RAD51 inhibitors

Keywords: RAD51 inhibitor; Indole alkaloid; Breast cancer; Triple-negative; QSAR; Synthesis; DMAP; 4,4-dimethylaminopyridine; XTT; sodium 3′-[1-(phenylaminocarbonyl)-3,4-tetrazolium]-bis(4-methoxy-6-nitro-) benzene sulfonate; IBR; RAD51 inhibitor;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Synthesis, characterization and targeting chemotherapy for ovarian cancer of trastuzumab-SN-38 conjugates

Keywords: ADCs; antibody-drug conjugates; DAR; drug-to-antibody ratio; SALCL; systemic anaplastic large cell lymphoma; LC/MS/MS; liquid chromatography tandem mass spectrometry; DIC; N,N′-diisopropylcarbodiimide; DCC; dicyclohexylcarbodiimide; DCM; dichloromethane

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Synthesis and SAR studies of analogues of 4-(3,3-dimethyl-butyrylamino)-3,5-difluoro-N-thiazol-2-yl-benzamide (Lu AA41063) as adenosine A2A receptor ligands with improved aqueous solubility

Keywords: HATU; 2-(1H-7-azabenzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate; EDC; N-ethyl-N′-dimethylaminopropyl-carbodiimide hydrochloride; HOBt; 1-hydroxy-benzotriazole; DMAP; 4-dimethylaminopyridine; DMF; dimethylformamide; DMSO; dimethyl sulf

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Addition compounds between carbones, CL2, and main group Lewis acids: A new glance at old and new compounds

Keywords: Bipy; bipyridine; DCM; dichloromethane; DFT; density functional theory; DME; dimethoxyethane; DMSO; dimethylsulfoxide; DMAP; 4-dimethylaminopyridine; Dppm; tetraphenyldiphosphino methane; EDA; energy decomposition analysis; FLP; frustrated Lewis pair; HOM

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2015 سفارش ترجمه

Stereoselective synthesis of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors

Keywords: HMG-CoA reductase inhibitors; Statins; Chiral β-hydroxy-δ-lactone; Chiral 3,5-syn-diol acid; Asymmetric synthesis; Ac; acetyl; Ar; aryl; Bn; benzyl; Bz; benzoyl; n-Bu; butyl; t-Bu; tert-butyl; CDI; 1,1′-carbonyldiimidazole; BINOL; 1,1′-bi-2-naphthol

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2015 سفارش ترجمه

Aromatic abietane diterpenoids: total syntheses and synthetic studies

Keywords: Diterpene; Abietane; Total synthesis; Semisynthesis; AcCl; acetyl chloride; Ac2O; acetic anhydride; BnCl; benzyl chloride; n-BuLi; n-butyllithium; DCC; N,N′-dicyclohexylcarbodiimide; DCM; dichloromethane; DDQ; 2,3-dichloro-5,6-dicyano-1,4-benzoquinone;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2015 سفارش ترجمه

Beyond Triphos - New hinges for a classical chelating ligand

Keywords: R′EP3R; in general structures with general formula R′E(CH2PR2)3; AACVD; aerosol-assisted chemical vapour deposition; acac; acetylacetone; ATRA; atom-transfer radical additions; ATRP; atom-transfer radical polymerization; cod; 1,5-cyclooctadiene; Cp−

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2015 سفارش ترجمه

(−)-Meptazinol-melatonin hybrids as novel dual inhibitors of cholinesterases and amyloid-β aggregation with high antioxidant potency for Alzheimer's therapy

Keywords: AD; Alzheimer's disease; Aβ; amyloid-β; ACh; acetylcholine; AChE; acetylcholinesterase; AChEIs; acetylcholinesterase inhibitors; BChE; butyrylcholinesterase; BBB; blood-brain barrier; CAS; catalytic anionic site; ChEs; cholinesterases; CCK-8; cell c

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2015 سفارش ترجمه

An update on the stereoselective synthesis of α-aminophosphonic acids and derivatives

Keywords: α-Aminophosphonic acids; α-Aminophosphonates; Stereoselective synthesis; Three-component reaction; ABSA; 4-acetamidobenzenesulfonyl azide; Abu; aminobutyric acid; Ac; acetyl; ACE; angiotensin-converting enzyme; Ala; alanine; Ar; aryl; BINAP; 2,2′-bis(

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2015 سفارش ترجمه

Is RK-682 a promiscuous enzyme inhibitor? Synthesis and in vitro evaluation of protein tyrosine phosphatase inhibition of racemic RK-682 and analogues

Keywords: Tyrosine phosphatases inhibitors; Natural 3-acyl-5-hydroxymethyltetronic acid; RK-682; Meldrum's acid derivatives; Enzyme inhibition; Promiscuous enzyme inhibition; PTP-1B; protein tyrosine phosphatase 1B; LMW-PTP; low molecular weight protein tyrosine ph

دانلود رایگان متن کامل مقاله ISI 105 صفحه سال انتشار : 2015 سفارش ترجمه

Synthesis of {[5-(adenin-9-yl)-2-furyl]methoxy}methyl phosphonic acid and evaluations against human adenylate kinases

Keywords: ADP; adenosine diphosphate; AK; adenylate kinase; ANP; acyclic nucleotide phosphonate; AMP; adenosine monophosphate; AMPK; AMP-activated kinase; ATP; adenosine triphosphate; Ap4P; P1,P4-di(adenosine-5′) tetraphosphate; Ap5P; P1,P5-di(adenosine-5′)pent

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Design and synthesis of novel small molecule CCR2 antagonists: Evaluation of 4-aminopiperidine derivatives

Keywords: AcOH; acetic acid; Boc; tert-butyloxycarbonyl; CCL2; chemokine ligand 2; CCR2; chemokine receptor 2; DCE; dichloroethane; DCM; dichloromethane; DIPEA; N,N-diisopropylethylamine; DMAP; N,N-dimethylaminopyridine; DMSO; dimethylsulfoxide; INCB3344; N-(2-(((3

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

A DMAP-catalyzed mild and efficient synthesis of 1,2-dihydroquinazolines via a one-pot three-component protocol

Keywords: Multicomponent reaction; 1,2-Dihydroquinazolines; DMAP; 2-Aminobenzophenone;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

A total synthesis of a highly N-methylated cyclodepsipeptide [2S,3S-Hmp]-aureobasidin L using solid-phase methods

Keywords: Aureobasidin; N-Methylated cyclodepsipeptide; Depsidipeptide; Fmoc-based solid-phase peptide synthesis; Boc; tert-butyloxycarbonyl; BTC; bis-(trichloromethyl)-carbonate; 13C NMR; carbon-13 nuclear magnetic resonance; COSY; correlation spectroscopy; DBU; 1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Design, synthesis and biological evaluation of new 5-nitro benzimidazole derivatives as AT1 antagonists with anti-hypertension activities

Keywords: RAS; rennin-angiotensin system; AII; angiotensin II; ARBs; angiotensin II receptor blockers; FDA; US Food and Drug Administration; DMAP; 4-(dimethylamino)pyridine; NMR; nuclear magnetic resonance; HRMS; high-resolution mass spectrometry; ESI; electrospr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Allosteric modulators of human A2B adenosine receptor

Keywords: ADA; adenosine deaminase; AR; adenosine receptor; cAMP; 3′,5′-cyclic adenosine monophosphate; BAY 60-6583; 2-[6-amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]pyridin-2-ylsulfanyl]acetamide; CHO; Chinese hamster ovary; DMAP; 4-dimethylaminopyridine

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Stereoselective total synthesis of cananginones (D-I) using Ireland-Claisen rearrangement as a key step

Keywords: Cananginones; Ireland-Claisen rearrangement; Cadiot-Chodkiewicz coupling; Sonogashira reaction; Lactonization; TBAI; tetrabutyl ammonium iodide; TMSI; trimethyl sulphonium iodide; DCC; N,N′-dicyclohexylcarbodiimide; DMAP; 4-dimethylaminopyridine; Li

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Tetrahedron report number 1048Synthesis and synthetic chemistry of pleuromutilin

Keywords: Pleuromutilin; Total synthesis; Medicinal chemistry; Antibacterials; Ac; acyl; AIBN; Azobisisobutyronitrile; Bn; benzyl; cap; caprolactamate; CYP; cytochrome P450; DIBAL; diisobutylaluminium hydride; DLP; dilauroyl peroxide; DMAP; N,N-dimethylaminopyridin

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2014 سفارش ترجمه

Intramolecular Diels-Alder reaction as a key step in tandem or sequential processes: a versatile tool for the synthesis of fused and bridged bicyclic or polycyclic compounds

Keywords: Diels-Alder; Natural product; One-pot; Sequential; Tandem; IMDA; intramolecular Diels-Alder; IMHDA; intramolecular hetero Diels-Alder; DA; Diels-Alder; IEDDA; intramolecular inverse-electron-demand Diels-Alder; DAIB or DIB; diacetoxyiodobenzene;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2014 سفارش ترجمه

Discovery of potent N-(isoxazol-5-yl)amides as HSP90 inhibitors

Keywords: HSP90; Fragment-based drug discovery; Crystallography; CDI; 1,1′-carbonyldiimidazole; DCM; dichloromethane; DHP; 3,4-dihydro-2H-pyran; DMAP; 4-dimethylaminopyridine; DMF; N,N-dimethylformamide; LHMDS; lithium hexamethyldisilazide;

دانلود رایگان متن کامل مقاله ISI 58 صفحه سال انتشار : 2014 سفارش ترجمه

Rapid access to homoallylic alcohols via Pd(OAc)2 catalyzed Barbier type allylation in presence of DMAP

Keywords: Barbier allylation; Allyl bromide; SnCl2; Pd(OAc)2; DMAP;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Discovery of a new HIV-1 inhibitor scaffold and synthesis of potential prodrugs of indazoles

Keywords: CDKs; cyclin-dependent kinases; CKII; casein kinase 2; DMAP; dimethylaminopyridine; EDCI; N-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride; LIMK; LIM kinases; PK; pharmacokinetics; TFA; trifluoroacetic acid; HIV; Drug target; Oxazoles; Prodrugs

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Discovery and SAR studies of methionine-proline anilides as dengue virus NS2B-NS3 protease inhibitors

Keywords: HQRJJHXKCFABSI-UONOGXRCSA-N; SAR; structure and activity relationship; NS2B-NS3; nonstructural protein 2B and 3; DENV; dengue virus; Ki; inhibition constant; TFA; trifluoroacetic acid; EtOAc; ethyl acetate; DCM; dichloromethylene; EtOH; ethyl alcohol; DMA

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Small-molecule inhibition of the uPAR·uPA interaction: Synthesis, biochemical, cellular, in vivo pharmacokinetics and efficacy studies in breast cancer metastasis

Keywords: uPAR; urokinase receptor; uPA; urokinase-type plasminogen activator; suPAR; soluble urokinase receptor; uPAATF; amino terminal fragment of uPA; MMP; matrix metalloproteinase; FP; fluorescence polarization; NOD/SCID; non-obese diabetic severe combined immu

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Effects of mycophenolic acid-glucosamine conjugates on the base of kidney targeted drug delivery

Keywords: CKD; chronic kidney disease; MGC; mycophenolic acid-glucosamine conjugate; MPA; mycophenolic acid; LMWC; low molecular weight chitosan; MMF; mycophenolate mofetil; DMF; N,N-Dimethylformamide; DCM; dichloromethane; DCC; dicyclohexylcarbodiimide; DMAP; 4-

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه