دانلود مقالات ISI درباره Dna-Pkcs + ترجمه فارسی

Ionizing-radiation induced DNA double-strand breaks: A direct and indirect lighting up

Keywords: bp; base-pair; DDR; DNA damage response; DNA-PKcs; catalytic subunit of the DNA-dependent protein kinase; DSB; DNA Double-Strand Break; HR; homologous recombination; IR; ionizing radiation; IRIF; ionizing radiation induced foci; LET; Linear Energy Transfe

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

XRCC1 deficiency increased the DNA damage induced by γ-ray in HepG2 cell: Involvement of DSB repair and cell cycle arrest

Keywords: XRCC1 gene; Hepatocellular carcinoma cells; γ-ray irradiation; DNA damage; DNA repair; BER; base excision repair; DNA-PKcs; DNA-dependent protein kinase catalytic subunit; DSB; double strand break; DSBR; double strand break repair; gadd153; growth arrest

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Studying the cerebellar DNA damage response in the tissue culture dish

Keywords: 53BP1; p53 binding protein 1; AOA1/2; ataxia with oculomotor apraxia type 1; A-T; ataxia-telangiectasia; A-TLD; ataxia-telangiectasia-like disorder/disease; ATM; ataxia-telangiectasia, mutated; ATR; ATM- and Rad3-related protein kinase; CaBP; calbindin pr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Inhibition of ERK activation enhances the repair of double-stranded breaks via non-homologous end joining by increasing DNA-PKcs activation

Keywords: ERK1/2 kinases; DNA damage repair; Non-homologous end joining (NHEJ); DNA damage response (DDR); Ku; DNA-PKcs;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Oxidative stress, DNA damage, and the telomeric complex as therapeutic targets in acute neurodegeneration

Keywords: MDA; malondialdehyde; 4-HNE; 4-hydroxynonenal; EAE; experimental allergic encephalomyelitis; MS; mutiple sclerosis; SSB; single strand break; DSB; double strand break; 8-OxoG; 8-hydroxyguanosine; 8-NO(2)-G; 8-nitroguanine; AP; apurinic/apyrmidinic; OGG1;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

DNA repair mechanisms in dividing and non-dividing cells

Keywords: DNA repair; Neural cells; Neurological disorder; Dividing and non-dividing; Endogenous DNA damage; AOA1; ataxia with ocular motor apraxia 1; AP; apurinic/apyrimidinic; APE1; AP endonuclease 1; APTX; aprataxin; ATM; ataxia telangiectasia mutated; CPDs; cyc

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه

The catalytic subunit of DNA-dependent protein kinase is downstream of ATM and feeds forward oxidative stress in the selenium-induced senescence response

Keywords: ATM; ataxia-telangiectasia mutated; CM-H2DCFDA; 5-(and-6)-chloromethyl-2',7'-dichlorodihydrofluorescein diacetate, acetyl ester; DAPI; 4,6-diamidino-2-phenylindole; DNA-PKcs; the catalytic subunit of DNA-dependent protein kinase; DSBs; double-strand bre

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Instability at the FRA8I common fragile site disrupts the genomic integrity of the KIAA0146, CEBPD and PRKDC genes in colorectal cancer

Keywords: DNA-PKcs; L1 (LINE); Isochromosome 8q; IGH translocation; BCP-ALL;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Lipofection and nucleofection of substrate plasmid can generate widely different readings of DNA end-joining efficiency in different cell lines

Keywords: Non-homologous end-joining (NHEJ); DNA double strand breaks (DSB); Nucleofection; Lipofection; Ku; DNA-PKcs; DNA Ligase IV

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Regulation of DNA repair by S-nitrosylation

Keywords: 8-oxoG; 8-oxoguanine; AGT; O6-alkylguanine-DNA-alkyltransferase; AP; apurinic-apyrimidinic; APE1; AP endonuclease 1; BER; base excision repair; DEN; diethylnitrosamine; DNA-PKcs; DNA-dependent protein kinase catalytic subunit; DSB; double-strand break; DT

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Inhibition of DNA-dependent protein kinase promotes ultrasound-induced cell death including apoptosis in human leukemia cells

Keywords: Ultrasound; DNA-PKcs; Akt; ATM; Cell death; Apoptosis

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

c-Jun N-terminal kinase controls a negative loop in the regulation of glial fibrillary acidic protein expression by retinoic acid

Keywords: GFAP; c-Jun N-terminal kinase; retinoic acid; neural precursor cells; BMP-2; bone morphogenetic protein-2; DNA-PKcs; DNA-protein kinase catalytic subunit; ERK; extracelular-regulated kinase; GFAP; glial fibrillary acidic protein; GSK-β; glycogen synthase

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

ATM and DNA-PKcs make a complementary couple in DNA double strand break repair

Keywords: ATM; DNA-PKcs; DSB repair; Residual DSBs; Illegitimate repair

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

New insights into the roles of ATM and DNA-PKcs in the cellular response to oxidative stress

Keywords: ATM; DNA-PKcs; ATR; Oxidative stress; Hypoxia; OCDL;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Negative regulation of human U6 snRNA promoter by p38 kinase through Oct-1

Keywords: PMA; phorbol 12-myristate 13-acetate; snRNA; small nuclear RNA; RNA Pol III; RNA polymerase III; PSE; proximal sequence element; DSE; distal sequence element; SNAPc; snRNA activating-protein complex; MAPK; mitogen-activated protein kinase; ERKs; extracell

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Identification and Characterization of a Small Inhibitory Peptide That Can Target DNA-PKcs Autophosphorylation and Increase Tumor Radiosensitivity

Keywords: DNA-PKcs; Peptides; Radiosensitivity;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

The hormesis effect of BDE-47 in HepG2 cells and the potential molecular mechanism

Keywords: BDE-47; ROS; DNA-PKcs; Akt; Cyclin D1; Hormesis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

DNA polymerase μ is a global player in the repair of non-homologous end-joining substrates

Keywords: Gapped DNA synthesis; Wortmannin; NU7441; DNA-PKcs; Alternative NHEJ; Microhomology;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

c-Myc Suppression of DNA Double-strand Break Repair

Keywords: HR; homologous recombination; NHEJ; nonhomologous end-joining; DSB; DNA double-strand break; PFGE; pulsed-field gel electrophoresis; siRNA; small interfering RNA; RNAi; RNA interference; DOX; doxycycline; DNA-PKcs; DNA-dependent protein kinase catalytic s

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2012 سفارش ترجمه

Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: The molecular choreography

Keywords: 53BP1; Tp53 binding protein 1; 9-1-1; RAD9-RAD1-HUS1 checkpoint clamp complex; a.a.; amino acid; ACF1; ATP-utilizing chromatin assembly and remodeling factor 1; ALC1; amplified in liver cancer 1; APLF/PALF; aprataxin and PNKP-like factor; Aprataxi

دانلود رایگان متن کامل مقاله ISI 89 صفحه سال انتشار : 2012 سفارش ترجمه

microRNA-7 increases radiosensitivity of human cancer cells with activated EGFR-associated signaling

Keywords: miRNA; microRNA; EGFR; epidermal growth factor receptor; PI3K; phosphatidyl inositide 3 kinase; DNA-PKcs; DNA-dependent protein kinase; microRNA-7; EGFR; PI3K; Akt; Radiosensitivity;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Radiosensitizing Effects of Ectopic miR-101 on Non-Small-Cell Lung Cancer Cells Depend on the Endogenous miR-101 Level

Keywords: Ionizing radiation; miR-101; Radiation sensitization; Non-small-cell lung cancer cells; ATM; DNA-PKcs;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Function of erbB receptors and DNA-PKcs on phosphorylation of cytoplasmic and nuclear Akt at S473 induced by erbB1 ligand and ionizing radiation

Keywords: P-Akt (S473); DNA-PKcs; Ionizing radiation; erbB1-ligands;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Survivin inhibition and DNA double-strand break repair: A molecular mechanism to overcome radioresistance in glioblastoma

Keywords: Survivin; Glioblastoma; DNA-repair; DNA-PKcs; Apoptosis; Phospho-histone H2AX;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

K-RAS(V12) Induces Autocrine Production of EGFR Ligands and Mediates Radioresistance Through EGFR-Dependent Akt Signaling and Activation of DNA-PKcs

Keywords: K-RAS mutation; DNA-PKcs; EGFR ligands; Radiation resistance;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Choosing the right path: Does DNA-PK help make the decision?

Keywords: a-NHEJ; alternative non-homologous end joining; B-NHEJ; backup non-homologous end joining; c-NHEJ; classical non-homologous end joining; DNA-PK; DNA-dependent protein kinase; DNA-PKcs; DNA-dependent kinase catalytic subunit; DSB; double strand break; HR;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

Gene expression in benzene-exposed workers by microarray analysis of peripheral mononuclear blood cells: Induction and silencing of CYP4F3A and regulation of DNA-dependent protein kinase catalytic subunit in DNA double strand break repair

Keywords: Benzene; Microarray; CYP4F3; DNA-PKcs; DNA double strand break repair;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Radiation-Induced Survivin Nuclear Accumulation is Linked to DNA Damage Repair

Keywords: Survivin; Colorectal cancer; DNA repair; DNA-PKcs; MDC1; Phospho-histone H2AX;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

DNA-PKcs deficiency leads to persistence of oxidatively induced clustered DNA lesions in human tumor cells

Keywords: Oxidative clustered DNA lesions; DNA-PKcs; Cancer; DNA damage; γ-H2AX; Free radicals

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Accessibility of chromosomal recombination breaks in nuclei of wild-type and DNA-PKcs-deficient cells

Keywords: DNA-PKcs; RAG1; RAG2; Scid; V(D)J recombination;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Enhanced gene amplification in human cells knocked down for DNA-PKcs

Keywords: Gene amplification; Double minutes; DNA-PKcs; shRNA; Human cells

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Sensitization of human K562 leukemic cells to TRAIL-induced apoptosis by inhibiting the DNA-PKcs/Akt-mediated cell survival pathway

Keywords: TRAIL; DNA-PKcs; Death receptors; Akt; Apoptosis; DMNB

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Tissue-specific DNA-PK-dependent H2AX phosphorylation and γ-H2AX elimination after X-irradiation in vivo

Keywords: DSB, DNA double-strand break; ECL, enhanced chemiluminescence; γ-H2AX, phosphorylated H2AXATM; DNA-PKcs; Histone H2AX phosphorylation; Ionizing radiation; SCID

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Ku, Artemis, and ataxia-telangiectasia-mutated: Signalling networks in DNA damage

Keywords: AT; ataxia-telangiectasia; ATM; ataxia-telangiectasia-mutated; ATR; ataxia-telangiectasia and Rad3-related; DNA-PK; DNA-dependent protein kinase; DNA-PKcs; catalytic subunit of DNA-dependent protein kinase; DSBs; double-strand breaks; ROS; reactive oxygen

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Stimulation of the DNA unwinding activity of human DNA helicase II/Ku by phosphorylation

Keywords: DNA binding; DNA-dependent ATPase; DNA-PKcs; DNA metabolism; DNA unwinding enzyme; HDH II/Ku; Protein phosphorylation; Protein dephosphorylation

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Radioprotection of 4-hydroxy-3,5-dimethoxybenzaldehyde (VND3207) in culture cells is associated with minimizing DNA damage and activating Akt

Keywords: Vanillin derivative; DNA repair; Radioprotection; Free radical; Akt; DNA-PKcs

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Distinct effects of DNA-PKcs and Artemis inactivation on signal joint formation in vivo

Keywords: TR; T cell receptor; Ig; immunoglobulin; RSS; recombination signal sequence; SE; signal end; CE; coding end; SJ; signal joint; CJ; coding joint; NHEJ; non-homologous end joining; DSB; double strand break; TdT; terminal nucleotidyl transferase; DNA-PK; DNA

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Processing of clustered DNA damage in human breast cancer cells MCF-7 with partial DNA-PKcs deficiency

Keywords: Clustered DNA damage; Human breast cancer; DNA-PKcs; Oxidative stress

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

PI3K-Akt signaling regulates basal, but MAP-kinase signaling regulates radiation-induced XRCC1 expression in human tumor cells in vitro

Keywords: XRCC1; Ionizing radiation; DNA-PKcs; PI3K/Akt;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Elevated levels of Ser/Thr protein phosphatase 5 (PP5) in human breast cancer

Keywords: DCIS; ductal carcinoma in situ; IDC; invasive ductal carcinoma; FACS; fluorescence activated cell sorting; ASK1; apoptosis signal regulating kinase 1; HIF-1; hypoxia inducible factor 1; MKK4; Map-kinase kinase-4; DNA-PKcs; DNA-dependent ser/thr protein ki

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Dynamic change of histone H2AX phosphorylation independent of ATM and DNA-PK in mouse skin in situ

Keywords: DSB, DNA double-strand break; ECL, enhanced chemiluminescence; ORS, outer root sheath; γ-H2AX, phosphorylated H2AXATM; DNA-PKcs; Histone H2AX phosphorylation; Ionizing radiation; Skin

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

WRN counteracts the NHEJ pathway upon camptothecin exposure

Keywords: RecQ; WRN; Ku70; DNA-PKcs; DT40; BLM; CPT; TopI; Etoposide; PARP-1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

DNA-PKcs-Dependent Modulation of Cellular Radiosensitivity by a Selective Cyclooxygenase-2 Inhibitor

Keywords: Cellular radiosensitivity; Celecoxib; DNA-PKcs; Chinese hamster ovarian; Cycloxoygenase-2 inhibitors;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Induction of apoptosis and autophagic cell death by the vanillin derivative 6-bromine-5-hydroxy-4-methoxybenzaldehyde is accompanied by the cleavage of DNA-PKcs and rapid destruction of c-Myc oncoprotein in HepG2 cells

Keywords: Vanillin derivative; Apoptosis; Autophagy; DNA damage; DNA-PKcs; c-Myc; Antiproliferation

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Partial deficiency of DNA-PKcs increases ionizing radiation-induced mutagenesis and telomere instability in human cells

Keywords: Partial deficiency; DNA-PKcs; Ionizing radiation; Mutagenesis; Telomere

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

The DNA repair complex DNA-PK, a pharmacological target in cancer chemotherapy and radiotherapy

Keywords: DNA repair; DNA-dependent protein kinase (DNA-PK); Chemotherapy; RadiotherapyRéparation de l'ADN; Protéine kinase dépendante de l'ADN (DNA-PK); Chimiothérapie; RadiothérapieCLL, chronic lymphocytic leukemia; DNA-PK, DNA-dependent protein kinase; DNA-PKcs

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

HIV-1 Tat depresses DNA-PKCS expression and DNA repair, and sensitizes cells to ionizing radiation

Keywords: HIV-1 Tat; DNA-PKcs; DNA repair; Cell cycle arrest; Radiosensitivity;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Expressions of Ku70 and DNA-PKcs as prognostic indicators of local control in nasopharyngeal carcinoma

Keywords: Chemotherapy; DNA-PKcs; Immunohistochemistry; Nasopharyngeal carcinoma; Radiotherapy; Ku70;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Construction of a novel expression system on a human artificial chromosome

Keywords: Human artificial chromosome; Tetracycline-regulatable system; Expression control; Insulator; DNA-PKcs; V3; DNA repair; Microcell-mediated chromosome transfer;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Shortened telomeres in murine scid cells expressing mutant hRAD54 coincide with reduction in recombination at telomeres

Keywords: Telomeres; DNA-PKcs; RAD54; Recombination; CO-FISH;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه