دانلود مقالات ISI درباره واکنش به آسیب DNA + ترجمه فارسی

Dietary restriction delays the secretion of senescence associated secretory phenotype by reducing DNA damage response in the process of renal aging

Keywords: واکنش به آسیب DNA ; Renal aging; DNA damage response; Dietary restriction; NF-κB; Senescence-associated secretory phenotypes;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Negative regulation of BRCA1 by transforming acidic coiled-coil protein 3 (TACC3)

Keywords: واکنش به آسیب DNA ; TACC3; DNA damage response; Genomic instability; BRCA1; BARD1; Protein stability;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Broad spectrum detection of DNA damage by Repair Assisted Damage Detection (RADD)

Keywords: واکنش به آسیب DNA ; RADD; repair assisted DNA damage detection; TUNEL; Terminal deoxynucleotidyl transferase nick end labeling; ISEL; In situ end label; DDR; DNA damage response; TdT; terminal deoxynucleotidyl transferase; dUTP; deoxyuracil triphosphate; CSK; cytoskeletal bu

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Transcriptome-based biological dosimetry of gamma radiation in Arabidopsis using DNA damage response genes

Keywords: واکنش به آسیب DNA ; Phytodosimetry; Arabidopsis thaliana; Transcriptome; DNA damage response;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Induction of reproductive cell death in Caenorhabditis elegans across entire linear-energy-transfer range of carbon-ion irradiation

Keywords: واکنش به آسیب DNA ; Carbon-ion irradiation; Bragg peak; Range-distribution; Reproductive cell death; DNA damage response; Vulval tissue model;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

PATRIOT: A phase I study to assess the tolerability, safety and biological effects of a specific ataxia telangiectasia and Rad3-related (ATR) inhibitor (AZD6738) as a single agent and in combination with palliative radiation therapy in patients with solid

Keywords: واکنش به آسیب DNA ; Phase I; Radiosensitization; ATR inhibition; DNA damage response; Clinical trial;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Phase 2 Trial of Gemcitabine, Cisplatin, plus Ipilimumab in Patients with Metastatic Urothelial Cancer and Impact of DNA Damage Response Gene Mutations on Outcomes

Keywords: واکنش به آسیب DNA ; Urothelial cancer; Immunotherapy; CTLA-4; Gemcitabine; Cisplatin; Chemotherapy; DNA damage response; DDR; Metastatic;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

DNA damage response genes mark the early transition from colitis to neoplasia in colitis-associated colon cancer

Keywords: واکنش به آسیب DNA ; DDR; DNA Damage Response; IBD; Inflammatory Bowel Disease; CAC; Colitis-Associated Cancer; MSI; microsatellite instability; AOM; Azoxymethane; DSS; Dextran sodium sulfate; HMSL; high magnification surgical lenses; MVT; macroscopically visible tumor; NMVT;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Enhanced H3K4me3 modifications are involved in the transactivation of DNA damage responsive genes in workers exposed to low-level benzene

Keywords: واکنش به آسیب DNA ; Benzene; Histone modification; H3K4me3; Hematotoxicity; DNA damage response;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

hMTH1 is required for maintaining migration and invasion potential of human thyroid cancer cells

Keywords: واکنش به آسیب DNA ; ATC; anaplastic thyroid cancer; BER; base excision repair; CREB; cAMP response element binding protein; DAPI; 4′,6-diamidine-2-phenylindole dihydrochloride; DDR; DNA damage response; dNTP; deoxynucleoside triphosphate; DSBs; double-stand breaks; DTC; di

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

DNA damage, metabolism and aging in pro-inflammatory T cells

Keywords: واکنش به آسیب DNA ; EC; endothelial cell; ROS; reactive oxygen species; ATP; adenosine 5′-triphosphate; ER; endoplasmic reticulum; mtDNA; mitochondrial DNA; ETC; electron transport chain; mROS; mitochondrial ROS; NADPH; nicotinamide adenine dinucleotide phosphate; TNF-α;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

XPF plays an indispensable role in relieving silver nanoparticle induced DNA damage stress in human cells

Keywords: واکنش به آسیب DNA ; Silver nanoparticle; XPF; DNA damage response;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Eukaryotic DNA damage responses: Homologous recombination factors and ubiquitin modification

Keywords: واکنش به آسیب DNA ; DNA damage response; Homologous recombination repair pathway; Ubiquitin modification;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Neurotoxicity of cytarabine (Ara-C) in dorsal root ganglion neurons originates from impediment of mtDNA synthesis and compromise of mitochondrial function

Keywords: واکنش به آسیب DNA ; DRG; dorsal root ganglion; mtDNA; mitochondrial DNA; BER; base excision repair; NER; nucleotide excision repair; DDR; DNA damage response; OCR; oxygen consumption rate; PNS; peripheral nervous system; pol γ; DNA polymerase γ; ROS; reactive oxygen specie

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Serotype-specific restriction of wild-type adenoviruses by the cellular Mre11-Rad50-Nbs1 complex

Keywords: واکنش به آسیب DNA ; Adenovirus; DNA damage response; Serotypes; MRN; ATM; E4orf3;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Telomeric Recombination Induced by DNA Damage Results in Telomere Extension and Length Heterogeneity

Keywords: واکنش به آسیب DNA ; ALT; Alternative lengthening of telomeres; APBs; ALT-associated PML bodies; BIR; Break-induced replication; CO-FISH; Chromosome orientation fluorescence in situ hybridization; DDR; DNA damage response; DOX; Doxycycline; DSBs; Double-strand breaks; HR; Hom

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Melanoma antigen-D2 controls cell cycle progression and modulates the DNA damage response

Keywords: واکنش به آسیب DNA ; APC/C; anaphase-promoting complex or cyclosome; ATM; ataxia-telangiectasia mutated protein; ATR; ataxia-telangiectasia- and rad3-related protein; CDC20; cell division cycle protein 20; CDK; cyclin-dependent kinase; CHK1; checkpoint kinase 1; CHK2; checkpo

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

TERT regulates telomere-related senescence and apoptosis through DNA damage response in male germ cells exposed to BPDE in vitro and to B[a]P in vivo

Keywords: واکنش به آسیب DNA ; Benzo[a]pyrene; Benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide; Telomerase reverse transcriptase; DNA damage response; Reproductive toxicity;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

GIT2-A keystone in ageing and age-related disease

Keywords: واکنش به آسیب DNA ; AD; Alzheimer's disease; ArfGAP; ADP-ribosylation factor GTPase-activating proteins; AT; adipose tissue; ATM; Ataxia Telangiectasia Mutated; ATP; adenosine tri-phosphate; BRCA1; breast cancer type 1 susceptibility protein; CNS; central nervous system; D

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

Integrating plant and animal biology for the search of novel DNA damage biomarkers

Keywords: واکنش به آسیب DNA ; ARP; actin related protein; ASK; Arabidopsis SPK1-like; At; Arabidopsis thaliana; ATAF; arabidopsis transcription activation factor; ATM; ataxia telangiectasia mutated; ATR; ATM and Rad3-related; ATRIP; ATR-interacting protein; BARD; BRCA1-associated RING

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

SIPS as a model to study age-related changes in proteolysis and aggregate formation

Keywords: واکنش به آسیب DNA ; AGEs; advanced glycation endproducts; ALP; autophagy-lysosomal pathway; ATM; ataxia teleangiectasia mutated; BrdU; bromodeoxyuridine; DDR; DNA damage response; DOX; doxorubicin; HDFs; Human diploid fibroblasts; H2O2; hydrogen peroxide; ICAM; intercellular

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Harmines inhibit cancer cell growth through coordinated activation of apoptosis and inhibition of autophagy

Keywords: واکنش به آسیب DNA ; Harmine; Anticancer effect; DNA damage response; Autophagy; Apoptosis; ATR; ATM and Rad3-related; CPT; camptothecin; cck-8; cell count kit-8; Chk1; checkpoint kinase 1; DOX; doxorubicin; PARP; poly (ADP-ribose) polymerase; PI; propidium iodide; UPLC-Q-TOF

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

Is DNA damage indispensable for stress-induced senescence?

Keywords: واکنش به آسیب DNA ; Chromatin; DNA damage response; Oncogenes; Stress; Tumour supressors;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Acetylation of TIP60 at K104 is essential for metabolic stress-induced apoptosis in cells of hepatocellular cancer

Keywords: واکنش به آسیب DNA ; HAT; histone acetyltransferase; PTM; post translational modification; ROS; reactive oxygen species; PARP; poly ADP-ribose polymerase; Dox; doxycycline; TRRAP; transformation/transcription domain associated protein; p400; E1A binding protein p400; RUVBL1;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

The hypoxic tumor microenvironment in vivo selects tumor cells with increased survival against genotoxic stresses

Keywords: واکنش به آسیب DNA ; Checkpoint kinases; DNA damage response; Hypoxia; Tumor microenvironment; Xenograft;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

High-throughput gene expression analysis identifies p53-dependent and -independent pathways contributing to the adrenocortical dysplasia (acd) phenotype

Keywords: واکنش به آسیب DNA ; TPP1; protein encoded by adrenocortical dysplasia gene; Acd; adrenocortical dysplasia gene; acd; adrenocortical dysplasia mutation; p53; transformation related protein 53; DNA; Deoxyribonucleic acid; DC; Dyskeratosis congenita; HHS; Hoyeraal-Hreidarsson s

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Antiviral activity of pyrrole-imidazole polyamides against SV40 and BK polyomaviruses

Keywords: واکنش به آسیب DNA ; DNA damage response; Mre11; SV40; Polyomavirus; BK polyomavirus; Polyamide; Antiviral;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

The FOXO3-FOXM1 axis: A key cancer drug target and a modulator of cancer drug resistance

Keywords: واکنش به آسیب DNA ; ABCB1; ATP-binding cassette sub-family B member 1; AML; acute myeloid leukaemia; AMPK; adenosine monophosphate-activated protein kinase; ATM; Ataxia-telangiectasia mutated; AURKA; aurora kinase A; BER; base excision repair; Bim; B-cell lymphoma 2 interact

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Mechanisms of DNA damage repair in adult stem cells and implications for cancer formation

Keywords: واکنش به آسیب DNA ; DNA damage response; Cancer mutational signatures; Stem cells; Cell of origin of cancer;

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

The identification of the ATR inhibitor VE-822 as a therapeutic strategy for enhancing cisplatin chemosensitivity in esophageal squamous cell carcinoma

Keywords: واکنش به آسیب DNA ; DNA damage response; Chemoresistance; ATM deficiency; ATR inhibitor;

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

Abnormal nuclear morphology is independent of longevity in a zmpste24-deficient fish model of Hutchinson-Gilford progeria syndrome (HGPS)

Keywords: واکنش به آسیب DNA ; CMV; cytomegalovirus; DDR; DNA damage response; GFP; green fluorescent protein; Gy; gray; H2B; histone H2B; n.s.; not significant; qPCR; quantitative polymerase chain reaction; s.d.; standard deviation; zmpste24; zinc metallopeptidase, STE24 homolog; Lami

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2018 سفارش ترجمه

Redox control of cancer cell destruction

Keywords: واکنش به آسیب DNA ; ABC transporters; ATP-binding cassette transporters; ADCC; antibody-dependent cell-mediated cytotoxicity; ADCP; antibody-dependent cancer cell phagocytosis; AML; acute myeloid leukemia; APE1; apurinic/apyrimidinic endonuclease 1; ASK-1; apoptosis signal-r

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2018 سفارش ترجمه

mTORC1 pathway in DNA damage response

Keywords: واکنش به آسیب DNA ; mTORC1 pathway; DNA damage response; PI3K-AKT; p53; SESTRINS; GATOR1; Autophagy; Mitochondria; Anticancer drugs;

دانلود رایگان متن کامل مقاله ISI 68 صفحه سال انتشار : 2018 سفارش ترجمه

R-loops cause genomic instability in T helper lymphocytes from patients with Wiskott-Aldrich syndrome

Keywords: واکنش به آسیب DNA ; Primary immunodeficiency; Wiskott-Aldrich syndrome; X-linked thrombocytopenia; TH1/TH2 differentiation; R-loops; DNA damage; genomic instability; ChIP; Chromatin immunoprecipitation; DDR; DNA damage response; DRB; 5,6-Dichlorobenzimidazole-1-β-D-ribofura

دانلود رایگان متن کامل مقاله ISI 87 صفحه سال انتشار : 2018 سفارش ترجمه

Impact of obesity and overweight on DNA stability: Few facts and many hypotheses

Keywords: واکنش به آسیب DNA ; AGEs; advanced glycation end products; AP-1; activating protein -1; APE1; apurinic/apyrimidinic endonuclease 1; BER; base excision repair; BMI; body mass index; CAF; cafeteria diet; CAT; Catalase; CBMN-Cyt; cytokinesis block micronucleus cytome assay; CEL

دانلود رایگان متن کامل مقاله ISI 89 صفحه سال انتشار : 2018 سفارش ترجمه

The RAG recombinase: Beyond breaking

Keywords: واکنش به آسیب DNA ; V(D)J recombination; RAG recombinase; DNA damage response; NHEJ; Adaptive immunity;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

The polyanionic C-terminal tail of human Rad17 regulates interaction with the 9-1-1 complex

Keywords: واکنش به آسیب DNA ; DNA damage response; Cell cycle checkpoint; ATR; Rad17; The 9-1-1 complex; a. a.; amino acids; ATR; ataxia telangiectasia and Rad3-related; endo.; endogenous; exo.; exogenous; iVERGE; IxxYxS in Vertebrates at the Edge of Rad17 with Glutamate/aspartate

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Experimental radiobiologyInhibition of ataxia telangiectasia related-3 (ATR) improves therapeutic index in preclinical models of non-small cell lung cancer (NSCLC) radiotherapy

Keywords: واکنش به آسیب DNA ; Ataxia telangiectasia related-3 (ATR); AZD6738; DNA damage response; Non-small cell lung cancer (NSCLC); Fibrosis; Small animal radiotherapy research platform (SARRP);

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Increase of DNA damage and alteration of the DNA damage response in myelodysplastic syndromes and acute myeloid leukemias

Keywords: واکنش به آسیب DNA ; Myelodysplastic syndromes; Acute myeloid leukemias; Genetic instability; DNA double-strand breaks; DNA damage response;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Increased age-adjusted hazard of death associated with a common single nucleotide polymorphism of the human RAD52 gene in a cardiovascular cohort

Keywords: واکنش به آسیب DNA ; Aging; DNA damage; RAD52; Double strand breaks; DNA damage response; Longitudinal study;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Taming Tricky DSBs: ATM on duty

Keywords: واکنش به آسیب DNA ; ATM; ataxia telangiectasia mutated; DSB; double strand breaks; DDR; DNA damage response; HR; homologous recombination; NHEJ; non-homologous end joining; PI3K; phosphoinositide 3-kinase; RNA pol II; RNA polymerase II; TAD; topologically associated domain;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

ReviewBalancing act: To be, or not to be ubiquitylated

Keywords: واکنش به آسیب DNA ; DNA double-strand breaks; DNA damage response; DNA repair; Ubiquitylation; Deubiquitylation;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Molecular radiobiologyG9a governs colon cancer stem cell phenotype and chemoradioresistance through PP2A-RPA axis-mediated DNA damage response

Keywords: واکنش به آسیب DNA ; G9a; CD133; DNA damage response; Chemoradioresistance; Cancer stem cells; PP2A;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Research paperA novel spliced variant of the TIN2 shelterin is present in chronic lymphocytic leukemia

Keywords: واکنش به آسیب DNA ; ACD or TPP1; adrenocortical dysplasia homolog; B2M; β2-microglobulin; CIRS; cumulative illness rating scale; CLL; chronic lymphocytic leukemia; DDR; DNA damage response; EV; empty vector; FL; full-length; HD; healthy donors; IGHV; immunoglobulin variable

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Modulating the DNA Damage Response to Improve Treatment Response in Cervical Cancer

Keywords: واکنش به آسیب DNA ; Cervical cancer; DNA damage response; HPV;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleThe depletion of ATM inhibits colon cancer proliferation and migration via B56γ2-mediated Chk1/p53/CD44 cascades

Keywords: واکنش به آسیب DNA ; ATM; Colon cancer; B56γ2; CD44; Tumorigenic potential; ATM; Ataxia-telangiectasia mutated; PIKK; phosphatidylinositol-3 kinase related kinase; FAT; FRAP-ATM-TRRAP domain; FATC; FAT-C-terminal domain; DDR; DNA damage response; DSBs; double strand breaks;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Cell cycle-dependent positive and negative functions of Fun30 chromatin remodeler in DNA damage response

Keywords: واکنش به آسیب DNA ; CPT; camptothecin; DDC; DNA damage checkpoint; DDT; DNA damage tolerance; DSB; double stranded DNA break; G6PD; Glucose-6-phosphate dehydrogenase; HR; homologous recombination; HU; hydroxyurea; MMS; methyl methanesulfonate; ssDNA; single stranded DNA; TLS

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

ARID2 modulates DNA damage response in human hepatocellular carcinoma cells

Keywords: واکنش به آسیب DNA ; Hepatocellular carcinoma; ARID2; DNA damage response; Nucleotide excision repair; SWI/SNF; XPC; CRISPR/Cas9; XPG; Benzo[a]pyrene;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Endosulfan induces cell dysfunction through cycle arrest resulting from DNA damage and DNA damage response signaling pathways

Keywords: واکنش به آسیب DNA ; Endosulfan; DNA damage; DNA damage response; HUVECs;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

DNA damage repair in breast cancer and its therapeutic implications

Keywords: واکنش به آسیب DNA ; DNA damage response; breast cancer; DDR; defects; therapeutic implications;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه