دانلود مقالات ISI درباره شکست دو رشته DNA + ترجمه فارسی

گلایکوزیدهای قلبی: از اهداف مولکولی تا مرگ سلولی ایمنولوژیک

Cardiac glycosides: From molecular targets to immunogenic cell death

Keywords: شکست دو رشته DNA; 53BP1; p53 binding protein 1; ACTH; adrenocorticotropic hormone; AIF; apoptosis-inducing factor; ATG5; autophagy-related 5; Bad; Bcl-2-associated death promoter; Bcl-2; B-cell lymphoma 2; Bcl-xL; B cell lymphoma extra-large; DSB; DNA double-strand break;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

نقاط نقد و بررسی و ارتباط با بیماری های انسانی

ReviewR Loops and Links to Human Disease

Keywords: شکست دو رشته DNA; DSB; DNA double-strand break; RNAP; RNA polymerase; FXS; fragile X syndrome; FXTAS; fragile X-associated tremor/ataxia syndrome; ssDNA; single-stranded DNA; G-Q; G-quadruplex; KD; knockdown; TDRD3; tudor domain-containing protein 3; FA; Fanconi anemia; AL

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

نقش مکانیزم های مرتبط با سرطان زایی در کاتاراکتوژنز و پیامدهای آن برای کاتاراکتوژنز تابش یونیزه

Role of carcinogenesis related mechanisms in cataractogenesis and its implications for ionizing radiation cataractogenesis

Keywords: شکست دو رشته DNA; Crystalline lens; Ionizing radiation; DNA repair factors; Nontargeted effects; Inflammation; Tumor suppressors; A-bomb; atomic-bomb; Acvr1; activin A type 1 receptor; AP; apurinic/apyrimidinic; APE1; apurinic/apyrimidinic endonuclease 1; AQP; aquaporin; A

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

شبکه هسته ای میتوکندری برای پایداری ژنوم

Mitochondria-nucleus network for genome stability

Keywords: شکست دو رشته DNA; used: AP; apurinic/apyrimidinic, i.e., abasic; BER; base excision repair; DSB; DNA double-strand break; 5′-dRP; 5′-deoxyribose phosphate; CIA; cytosolic iron-sulfur protein assembly; DG; DNA glycosylase; DRM(D); direct repeat-mediated (deletion); ET

دانلود رایگان متن کامل مقاله ISI 84 صفحه سال انتشار : 2015 سفارش ترجمه

سندرم شکستن نیهمگن: راه های ترخیص برای پروتئین نایروانی جهش یافته خاص آلل است

Nijmegen breakage syndrome: The clearance pathway for mutant nibrin protein is allele specific

Keywords: شکست دو رشته DNA; BRCT; BRCA1 C-Terminus; DSB; DNA double-strand break; LCL; lymphoblastoid cell line; NBN; nibrin; NBS; Nijmegen breakage syndrome; PMN; piecemeal microautophagy of the nucleus; RT-PCR; reverse transcription polymerase chain reaction; DNA repair; Proteasom

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Quantitative assessment of HR and NHEJ activities via CRISPR/Cas9-induced oligodeoxynucleotide-mediated DSB repair

Keywords: شکست دو رشته DNA; CRISPR/Cas9; Oligodeoxynucleotide; DNA double-strand break; Homologous recombination; Non-homologous end joining; DNA repair;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2018 سفارش ترجمه

Genotoxicity analysis of five particle matter toxicants from cigarette smoke based on γH2AX assay combined with Hill/Two-component model

Keywords: شکست دو رشته DNA; DSB; double-strand breaks; ELISA; enzyme-linked immunosorbent assay; WB; western blot; FC; flow cytometry; HCS; high content screening; PAHs; polyaromatic hydrocarbons; WHO FCTC; World Health Organization Framework Convention on Tobacco Control; CCK8; cel

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Outcome of hematopoietic cell transplantation for DNA double-strand break repair disorders

Keywords: شکست دو رشته DNA; Ataxia-telangiectasia; Cernunnos-XLF deficiency; DNA repair disorders; DNA ligase IV deficiency; hematopoietic stem cell transplantation; Nijmegen breakage syndrome; aGvHD; Acute graft-versus-host disease; AT; Ataxia-telangiectasia; ATG; Anti-thymocyte gl

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2018 سفارش ترجمه

Synthesis, cytotoxic evaluation and target identification of thieno[2,3-d]pyrimidine derivatives with a dithiocarbamate side chain at C2 position

Keywords: شکست دو رشته DNA; Thieno[2,3-d]pyrimidine; Dithiocarbamate; Cytotoxicity; Probe; Target identification; Tubulin; Boc; tert-butyloxycarbonyl; CPT; camptothecin; DMF; N,N-dimethylformamide; DMSO; dimethyl sulphoxide; DSB; DNA double-strand break; EDCI; 1-ethyl-3-(3-dimethyla

دانلود رایگان متن کامل مقاله ISI 70 صفحه سال انتشار : 2018 سفارش ترجمه

Defects in recombination activity caused by somatic and germline mutations in the multimerization/BRCA2 binding region of human RAD51 protein

Keywords: شکست دو رشته DNA; HR; homologous recombination; HDR; homology-directed repair; DSB; DNA double-strand break; dsDNA; double-stranded DNA; ssDNA; single-stranded DNA; WT; wild-type; NTD; N-terminal domain; RHD; RecA homology domain; RAD51; Recombination; Homology-directed re

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Radiation-induced DNA-protein cross-links: Mechanisms and biological significance

Keywords: شکست دو رشته DNA; C-ion; carbon-ion; DNMT; DNA methyltransferase; DPC; DNA-protein cross-link; DSB; DNA double-strand break; FITC; fluorescein isothiocyanate; GC-MS; gas chromatography-mass spectrometry; HR; homologous recombination; LET; linear energy transfer; MAR; mat

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Quantification and genome-wide mapping of DNA double-strand breaks

Keywords: شکست دو رشته DNA; DSB; DNA double-strand break; SSB; DNA single-strand break; TdT; terminal deoxynucleotidyl transferase; NGR; DNA nick and gap repair; dBrIC; DNA break immunocapture; qTUNEL; quantitative TUNEL; NGS; next-generation sequencing; %IP; percentage of immunopre

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Lovastatin protects keratinocytes from DNA damage-related pro-apoptotic stress responses stimulated by anticancer therapeutics

Keywords: شکست دو رشته DNA; 53BP1; tumor suppressor p53 binding protein 1; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and Rad3-related; Chk; checkpoint kinase; DSB; DNA double-strand break; DDR; DNA damage response; DNA-PKcs; DNA-dependent protein kinase, catalyt

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Repression of harmful meiotic recombination in centromeric regions

Keywords: شکست دو رشته DNA; DSB; DNA double-strand break; MI; first meiotic division; MII; second meiotic division; PSSC; precocious separation of sister chromatids; H3 K9me; histone H3 methylated on lysine 9; siRNA; small interfering RNA; IH; interhomolog; IS; intersister; MRN; Mre

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2016 سفارش ترجمه

Exo1 and Mre11 execute meiotic DSB end resection in the protist Tetrahymena

Keywords: شکست دو رشته DNA; Meiosis; Recombination; DNA double-strand break; Crossover;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

XRCC4 deficiency in human subjects causes a marked neurological phenotype but no overt immunodeficiency

Keywords: شکست دو رشته DNA; DNA double-strand break repair; nonhomologous end-joining; double-strand break repair deficiency; XRCC4/LIG4; immunodeficiency; microcephaly; CID; Combined immunodeficiency; CS; Cockayne syndrome; CSR; Class-switch recombination; DNA-PK; DNA-dependent pro

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Cell cycle regulation of human DNA repair and chromatin remodeling genes

Keywords: شکست دو رشته DNA; MMR; mismatch repair; NER; nucleotide excision repair; BER; base excision repair; DSB; DNA double-strand break; NHEJ; non-homologous end joining; HR; homologous recombination; FA; Fanconi anemia; SS; serum starvation; TT; double thymidine block; NZ; nocod

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

RecQ helicases and PARP1 team up in maintaining genome integrity

Keywords: شکست دو رشته DNA; ARTD; ADP-ribosyltransferase diphtheria toxin-like; BER; base excision repair; BG; Baller-Gerold syndrome; BLM; Bloom syndrome protein; BRCT; BRCA1 C-terminus domain; BS; Bloom syndrome; CPT; camptothecin; dHJ; double Holliday junction; DSB; DNA double-st

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

Induction of DNA double-strand breaks in primary gingival fibroblasts by exposure to dental resin composites

Keywords: شکست دو رشته DNA; Dental resin composites; HGFs; DNA damage; DNA double-strand break; γ-H2AX

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Protein ADP-ribosylation and the cellular response to DNA strand breaks

Keywords: شکست دو رشته DNA; DNA double-strand break; DNA single-strand break; Non-homologous end-joining; Homologous recombination; Single-strand break repair; Base excision repair; Poly(ADP-ribose) polymerase;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

The catalytic subunit of DNA-dependent protein kinase is required for cellular resistance to oxidative stress independent of DNA double-strand break repair

Keywords: شکست دو رشته DNA; APE1; apurinic/apyrimidinic endonuclease; A-T; ataxia telangiectasia; ATM; ataxia telangiectasia mutated; BER; base excision repair; DNA-PKcs; DNA-dependent protein kinase catalytic subunit; DSB; DNA double-strand break; ECL; enhanced chemiluminescence; F

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Mechanisms of cohesin-mediated gene regulation and lessons learned from cohesinopathies

Keywords: شکست دو رشته DNA; ChIP-loop; 3C combined with ChIP; ATR-X; Alpha-Thalassemia mental Retardation, X-linked; ARS; autonomously replicating sequence; CTCF; CCCTC-binding factor; ChIP; chromatin immunoprecipitation; ChIA-PET; Chromatin Interaction Analysis by Paired-End Tag se

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

NR4A nuclear receptors are orphans but not lonesome

Keywords: شکست دو رشته DNA; 6-MP; 6-mercaptopurine; 9-cis-RA; 9-cis-retinoic acid; AMP; adenosine monophosphate; AMPK; AMP-activated protein kinase; Cam-kinase; calcium/calmodulin-dependent protein kinase; CREB; cAMP response element binding protein; DBD; DNA-binding domain; DSB; DN

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Manual versus automated γ-H2AX foci analysis across five European laboratories: Can this assay be used for rapid biodosimetry in a large scale radiation accident?

Keywords: شکست دو رشته DNA; Biological dosimetry; Gamma-H2AX; Radiation-induced foci; Ionizing radiation; DNA double-strand break; Biomarker;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Ionizing-radiation induced DNA double-strand breaks: A direct and indirect lighting up

Keywords: شکست دو رشته DNA; bp; base-pair; DDR; DNA damage response; DNA-PKcs; catalytic subunit of the DNA-dependent protein kinase; DSB; DNA Double-Strand Break; HR; homologous recombination; IR; ionizing radiation; IRIF; ionizing radiation induced foci; LET; Linear Energy Transfe

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Cylindrospermopsin induced transcriptional responses in human hepatoma HepG2 cells

Keywords: شکست دو رشته DNA; AP-1; activator protein; BER; base excision repair; CDK; cyclin-dependant kinase; CDKI; cyclin-dependant kinase inhibitor; CYN; cylindrospermopsin; CYP450; cytochrome P450; DSB; DNA double-strand break; ER; endoplasmic reticulum; GST; glutathione S-transf

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Redox-regulating sirtuins in aging, caloric restriction, and exercise

Keywords: شکست دو رشته DNA; 8-oxoG, 8-oxo-7; 8-dihydroguanine; APE1; apurinic/apyrimidinic endonuclease 1; BER; DNA base excision repair; CR; caloric restriction; DSB; DNA double-strand break; FOXO; forkhead homeobox type O protein; eIF2α; eukaryotic initiation factor 2α; eNOS; en

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

A proteome-wide visual screen identifies fission yeast proteins localizing to DNA double-strand breaks

Keywords: شکست دو رشته DNA; Fission yeast; Schizosaccharomyces pombe; DNA double-strand break; DNA damage response; DNA repair; ORFeome

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

The histone variant macroH2A1.1 is recruited to DSBs through a mechanism involving PARP1

Keywords: شکست دو رشته DNA; ChIP; chromatin immunoprecipitation; BER; base excision repair; DSB; DNA double-strand break; HR; homologous recombination; mH2A1; macroH2A1; IF; immunofluorescence; IR; ionizing radiation; MMS; methylmethane sulfonate; MRN; Mre11-Rad50-Nbs1; NHEJ; non-ho

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

The BRCA1 alternative splicing variant Δ14-15 with an in-frame deletion of part of the regulatory serine-containing domain (SCD) impairs the DNA repair capacity in MCF-7 cells

Keywords: شکست دو رشته DNA; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and Rad3-related; AURKA; Aurora kinase A; BC; breast cancer; BRCA1/2; breast cancer-associated gene 1/2; BRCT; BRCA1 C-terminal domain; B2M; beta-2-microglobulin; Cdk2; cyclin-dependent kinase

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

γ-H2AX and other histone post-translational modifications in the clinic

Keywords: شکست دو رشته DNA; γ-H2AX focus; DNA double-strand break; Ionizing radiation; Biodosimeter; Chemotherapy; Clinical study

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

c-Myc Suppression of DNA Double-strand Break Repair

Keywords: شکست دو رشته DNA; HR; homologous recombination; NHEJ; nonhomologous end-joining; DSB; DNA double-strand break; PFGE; pulsed-field gel electrophoresis; siRNA; small interfering RNA; RNAi; RNA interference; DOX; doxycycline; DNA-PKcs; DNA-dependent protein kinase catalytic s

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2012 سفارش ترجمه

Residual DNA and chromosomal damage in ex vivo irradiated blood lymphocytes correlated with late normal tissue response to breast radiotherapy

Keywords: شکست دو رشته DNA; DNA double-strand break; γH2AX; Chromosomal aberration; Blood lymphocyte radiosensitivity; Late normal tissue damage;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Inter-individual and inter-cell type variation in residual DNA damage after in vivo irradiation of human skin

Keywords: شکست دو رشته DNA; DNA double-strand break; Inter-individual variation; Inter-cell type variation; In vivo irradiation; Human skin

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Recruitment of the cohesin loading factor NIPBL to DNA double-strand breaks depends on MDC1, RNF168 and HP1γ in human cells

Keywords: شکست دو رشته DNA; DNA double-strand break; DNA damage signaling; NIPBL; Heterochromatin protein 1;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks

Keywords: شکست دو رشته DNA; DNA double-strand break; Ubiquitin; SUMO; Chromatin; DNA repair;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Photosensitization by iodinated DNA minor groove binding ligands: Evaluation of DNA double-strand break induction and repair

Keywords: شکست دو رشته DNA; Phototherapy; Photochemotherapy; Iodinated DNA ligand; DNA double-strand break; γH2AX; Trichostatin A

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

MDC1 is ubiquitylated on its tandem BRCT domain and directly binds RAP80 in a UBC13-dependent manner

Keywords: شکست دو رشته DNA; BRCT; BRCA1 C-terminus; DDR; DNA damage response; DSB; DNA double-strand break; DUB; deubiquitinase; FHA; forkhead associated; GST; glutathione S-transferase; a.a.; amino acids; NCS; neocarzinostatin; IP; immunoprecipitate; IR; ionizing radiation; PTM; po

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

DNA double-strand break repair pathways, chromosomal rearrangements and cancer

Keywords: شکست دو رشته DNA; DNA double-strand break; Homologous recombination; Non-homologous end joining; Chromosomal rearrangement; Cancer

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Mechanisms of the formation of radiation-induced chromosomal aberrations

Keywords: شکست دو رشته DNA; DNA double-strand break; Radiation; Chromatid break mechanisms; Topoisomerase IIα, siRNA; Human lymphocytes

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Acetylation of H2AX on lysine 36 plays a key role in the DNA double-strand break repair pathway

Keywords: شکست دو رشته DNA; DSB; DNA double-strand break; IR; ionizing radiation; HAT; histone acetyltransferase; HDAC; histone deacetylase; H2AXK36Ac; H2AX acetylated on lysine 36; TSA; trichostatin A; H2AX; Acetylation; Chromatin; DNA double-strand break; Histone acetyltransferase

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Pathways for Double-strand Break Repair in Genetically Unstable Z-DNA-forming Sequences

Keywords: شکست دو رشته DNA; DSB, DNA double-strand break; NHEJ, non-homologous end-joining; HR, homologous recombination; ssDNA, single-stranded DNA; WT, wild type; LMPCR, linker-mediated PCR; Mt, Mycobacterium tuberculosisZ-DNA; DNA double-strand break; genetic instability; non-hom

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Cernunnos/XLF: A new player in DNA double-strand break repair

Keywords: شکست دو رشته DNA; Cernunnos; DNA double-strand break; DNA repair; Non-homologous end-joining; XLF

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

A Nonhomologous End-joining Pathway Is Required for Protein Phosphatase 2A Promotion of DNA Double-Strand Break Repair

Keywords: شکست دو رشته DNA; NHEJ; nonhomologous end-joining; DSB; DNA double-strand break; PP2A/C; protein phosphatase 2A catalytic subunit; small T; the SV40 small tumor antigen; PFGE; pulsed-field gel electrophoresis; HA; hemagglutinin; siRNA; small interfering RNA; RNAi; RNA inte

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2009 سفارش ترجمه

Radiation-induced bystander effects enhanced by elevated sodium chloride through sensitizing cells to bystander factors

Keywords: شکست دو رشته DNA; RIBE; radiation-induced bystander effects; MN; micronuclei; ROS; reactive oxygen species; NO; nitric oxide; DSB; DNA double-strand break; γ-H2AX; phosphorylated form of H2AX protein; Elevated NaCl; Radiation-induced bystander effect; α-Particle irradiat

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Flavopiridol Potentiates the Cytotoxic Effects of Radiation in Radioresistant Tumor Cells in Which p53 is Mutated or Bcl-2 is Overexpressed

Keywords: شکست دو رشته DNA; Flavopiridol; p53; Bcl-2; DNA double-strand break;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Deficiency in the response to DNA double-strand breaks in mouse early preimplantation embryos

Keywords: شکست دو رشته DNA; Preimplantation embryo; Check point; DNA double-strand break; DNA repair; γ-H2AX

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Cytogenetic study of the induction mechanism of chromosome-type aberrations by 1-β-d-arabinofuranosylcytosine

Keywords: شکست دو رشته DNA; 1-β-d-Arabinofuranosylcytosine; Chromosome-type aberration; DNA double-strand break; Endonucleolytic protein(s); DNA repair

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Phosphorylation of p53 at serine 15 in A549 pulmonary epithelial cells exposed to vanadate: Involvement of ATM pathway

Keywords: شکست دو رشته DNA; ATM; ataxia telangiectasia mutated; ATR; ATM-Rad3-related protein; DMSO; dimethyl sulfoxide; DNA-PK; DNA-activated protein kinase; DSB; DNA double-strand break; ERK; extracellular signal-regulated protein kinase; HRP; horseradish peroxidase; MAPK; mitogen

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

DNA double-strand break repair: From mechanistic understanding to cancer treatment

Keywords: شکست دو رشته DNA; Homologous recombination; DNA double-strand break; Non-homologous end joining; DNA damage response; Replication; DNA repair

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه