Keywords: 4- Shogaol (PubChem CID: 9794897); 6- Shogaol (PubChem CID: 5281794); Apigenin (PubChem CID: 5280443); Berberine (PubChem CID: 2353); Bergamottin (PubChem CID: 5471349); Caffeic acid (PubChem CID: 689043)Capsaicin (PubChem CID: 1548943); Cardamonin (PubCh
مقالات ISI (ترجمه نشده)
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Keywords: ACC1; acetyl-CoA carboxylase 1; AHCY; S-adenosylhomocysteine hydrolase; AMPK; AMP-activated protein kinase; ATGL; adipose triglyceride lipase; BHMT; betaine homocysteine methyltransferase; CD36; fatty acid translocase; CPT1α; carnitine palmitoyltransfera
Keywords: Oxysterols; Cancer; Polymorphism; Risk; Genetics; Cholesterol; 25(OH)D; 25-hydroxyvitamin D; ABC; ATP-binding cassette; AEBS; antiestrogen-binding site; BC; breast cancer; BCR; biochemical recurrence; CETP; cholesteryl ester transfer protein; CH25H; chole
Keywords: TME; tumour microenvironment; PD-1; programmed cell death 1; PD-L1; programmed death ligand 1; PD-L2; programmed death ligand 2; PTMs; post-translational histone modifications; DNMTi; DNA methyltransferase inhibitor; HDACi; histone deacetylase inhibitor;
Keywords: â¢OH; hydroxyl radical; 2,2-BP; 2,2-bipyridyl; ABC; ATP-binding cassette; AIF; apoptosis-inducing factor; AMPK; AMP-activated protein kinase; AMPKK; AMPK kinase; ANT; adenine nucleotide translocase; AP-1; activator protein 1; Apaf-1; protease activating
Keywords: 2-DG; 2-deoxyglucose; 2-HG; 2-hydroxyglutarate; 5mC; 5-methlycystosine; ACACA; acetyl-CoA carboxylase; AML; acute myeloid leukemia; AMPK; adenosine monophosphate-activated protein kinase; ATP; adenosine triphosphate; ALDH; aldehyde dehydrogenase; ADCs; an
Keywords: α-synuclein; Methamphetamine; DNA methylation; Methyl CpG binding protein 2; DNA methyltransferase 1;
Keywords: NAFLD; Non-alcoholic fatty liver disease; dG-TAM; (E)-α-(deoxyguanosin-N2-yl)-tamoxifen; dG-DesMeTAM; (E)-α-(deoxyguanosin-N2-yl)-N-desmethyltamoxifen; ALT; alanine transaminase; AST; aspartate transaminase; LDH; lactate dehydrogenase; α-SMA; α-smooth
Keywords: A; adenine; AFLP; amplified fragment length polymorphism; AHR; aryl-hydrocarbon receptor; As; arsenic; B[a]P; benzo[a]pyrene; BPA; Bisphenol A; C; cytosine; Cd; cadmium; CpA; cytosine-phosphate-adenine; CpG; cytosine-phosphate-guanine; Cr; chromium; C
Dietary betaine supplementation in hens modulates hypothalamic expression of cholesterol metabolic genes in F1 cockerels through modification of DNA methylation
Keywords: ACAT1; acetyl-CoA cholesterol acyltransferase 1; APOA1; apolipoprotein A1; BHMT; betaine homocysteine methyltransferase; BBB; blood brain barrier; CYP46A1; cholesterol 24-hydroxylase A 1; DNMT1; DNA methyltransferase 1; DNMT3A; DNA methyltransferase 3 A;
CCRK is a novel signalling hub exploitable in cancer immunotherapy
Keywords: 9G8; serine and arginine rich splicing factor 7; AKT; AKT serine/threonine kinase; AR; androgen receptor; ARE; androgen response element; ARG1; arginase 1; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and rad3-related protein; BMDC; mous
Regulation of cancer immune escape: The roles of miRNAs in immune checkpoint proteins
Keywords: Immune checkpoint proteins (ICPs); miRNAs; Cancer immune escape; Antigen-MHC; antigen-major histocompatibility complex; ICPs; immune checkpoint proteins; 3â²UTR; 3â² untransltated region; PD-1; programmed cell death protein; Tregs; regulatory T cells; H
Maternal betaine administration modulates hepatic type 1 iodothyronine deiodinase (Dio1) expression in chicken offspring through epigenetic modifications
Keywords: AHCYL1; adenosylhomocysteinase-like 1; BHMT; betaineâhomocysteineâSâmethyltransferase; DNMT1; DNA methyltransferase 1; Dio1; type 1 iodothyronine deiodinase; Dio2; type 2 iodothyronine deiodinase; Dio3; type 3 iodothyronine deiodinase; LAT1; L-type
DNMT1 mediated promoter methylation of GNAO1 in hepatoma carcinoma cells
Keywords: HCC; hepatic celluler cancer; GNAO1; Guanine nucleotide-binding protein α1; BSP; bisulfite sequence PCR; DAC; 5-Aza-2â²-deoxycytidine; TSA; Trichostatin A; DNMT-1; DNA methyltransferase 1; TGF-β; transforming growth factor β; Src; steroid receptor cof
Fresh red raspberry phytochemicals suppress the growth of hepatocellular carcinoma cells by PTEN/AKT pathway
Keywords: RRE; red raspberry extract; CCK8; cell counting Kit-8; DNMT1; DNA methyltransferase 1; PTEN; phosphatase and tensin homologue deleted on chromosome 10; HCC; hepatocellular carcinoma; HPLC; high performance liquid chromatography; LC-MS; liquid chromatogr
TRPM2 mediates mitochondria-dependent apoptosis of melanocytes under oxidative stress
Keywords: ROS; reactive oxygen species; MMP; mitochondrial membrane potential; TRPM2; transient receptor potential cation channel subfamily M member 2; H2O2; hydrogen peroxide; NHMs; Normal human melanocytes; NAC; N-acety-L-cysteine; Ru360; Ruthenium 360; 5-aza-dC;
HOTAIR-mediated reciprocal regulation of EZH2 and DNMT1 contribute to polyphyllin I-inhibited growth of castration-resistant prostate cancer cells in vitro and in vivo
Keywords: PPI; polyphyllin I; CRPC; castration-resistant prostate cancer; EZH2; Zeste homolog 2; DNMT1; DNA methyltransferase 1; HOTAIR; HOX transcript antisense RNA; ADT; androgen deprivation therapy; NF-κB; nuclear factor-kappaB; lncRNA; Long non-coding RNA; DNM
Presence of a consensus DNA motif at nearby DNA sequence of the mutation susceptible CG nucleotides
Keywords: TS; tumor suppressor; DNMT1; DNA methyltransferase 1; NTDs; nucleotides; AAs; amino acids; RMSD; root mean square deviation; MD; molecular dynamics; HB; hydrogen bond; PWM; position weight matrix; Mutation; Epigenetics; CpG islands; Tumor suppressors; Onc
Downregulation of microRNA-370 in esophageal squamous-cell carcinoma is associated with cancer progression and promotes cancer cell proliferation via upregulating PIN1
Keywords: EC; esophageal cancer; ESCC; esophageal squamous-cell carcinoma; EA; esophageal adenocarcinoma; PIN1; Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; RUX3; runt-related transcription factor 3; UTR; untranslated region; qRT-PCR; quantitative real-t
Long non-coding RNAs regulation in adipogenesis and lipid metabolism: Emerging insights in obesity
Keywords: lncRNAs; Obesity; White adipogenesis; Brown adipocyte differentiation; Lipid metabolism; Therapeutics; WAT; white adipose tissue; BAT; brown adipose tissue; Pparg; peroxisome proliferator-activated receptor γ; Cebpa; CCAAT/enhancer binding protein α; Fa
Multi-PK antibodies: Powerful analytical tools to explore the protein kinase world
Keywords: 2D-PAGE; two-dimensional polyacrylamide gel electrophoresis; CaMK; Ca2+/calmodulin-dependent protein kinase; CDKL5; cyclin-dependent kinase-like 5; CNBr; cyanogen bromide; DCLK; double-cortin like protein kinase; Dnmt1; DNA methyltransferase 1; FAK; focal
DNA methylation and histone deacetylation regulating insulin sensitivity due to chronic cold exposure
Keywords: Chronic cold exposure; DNA methylation; Histone deacetylation; Insulin resistance; Mitochondrion; CpG; cytosine-phosphate-guanine; cytC; cytochrome C; Dnmt1; DNA methyltransferase 1; DNMT3a; DNA methyltransferase 3a; FPG; fasting plasma glucose; FINS; fas
Innate immunity related pathogen recognition receptors and chronic hepatitis B infection
Keywords: acLDL; acylated LDL; AIM2; absent in melanoma 2; AP-1; activator protein 1; BDCA-2; blood DC antigen; BEC; biliary epithelial cells; CARD; caspase recruitment and activation domains; cDC; common dendritic cells; CL-L1; collectin liver 1; CL-K1; collectin
Dnmt1 activity is dispensable in δ-cells but is essential for α-cell homeostasis
Keywords: Cre; Cre recombinase; Dnmt1; DNA methyltransferase 1; Dox; doxycycline; DT; diphtheria toxin; DTR; diphtheria toxin receptor; Ezh2; enhancer of zeste homolog 2; Gcg; glucagon; IAP; intracisternal A-particle; Ins; insulin; m-o; month-old; PRC; polycomb rep
Dynamics and Context-Dependent Roles of DNA Methylation
Keywords: mES; murine embryonic stem; DNMT; DNA methyltransferase; DNMT3A; DNA methyltransferase 3A; DNMT3B; DNA methyltransferase 3B; DNMT1; DNA methyltransferase 1; H3K36me3; histone H3 lysine-36 trimethylation; ES; embryonic stem; UHRF1; ubiquitin-like with PHD
Subcellular distribution of cyclin-dependent kinase-like 5 (CDKL5) is regulated through phosphorylation by dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A)
Keywords: CDKL5; DYRK1A; Protein phosphorylation; Rett syndrome; Down syndrome; Amph1; amphiphysin 1; CDKL5; cyclin-dependent kinase-like 5; Dnmt1; DNA methyltransferase 1; DYRK1A; dual specificity tyrosine-phosphorylation-regulated kinase 1A; GST; glutathione S-tr
Epigenetic regulation of RELN and GAD1 in the frontal cortex (FC) of autism spectrum disorder (ASD) subjects
Keywords: 5fC; 5-formylcytosine; 5caC; 5-carboxycytosine; 5mC; 5-methylcytosine; 5hmC; 5-hydroxymethylcytosine; ACTB; b-actin; ASD; autism spectrum disorder; BA; Brodmann area; BDNF; brain derived neurotrophic factor; BDNF-IV; BDNF-promoter 4; BDNF-IX; BDNF-promote
The RNAs of RNA-directed DNA methylation
Keywords: AGO1; ARGONAUTE 1; AGO2; ARGONAUTE 2; AGO4; ARGONAUTE 4; AGO6; ARGONAUTE 6; CLSY1; CLASSY 1; CMT2; CHROMOMETHYLASE 2; CMT3; CHROMOMETHYLASE 3; CTD; carboxy-terminal domain; DCL1; DICER-LIKE 1; DCL2; DICER-LIKE 2; DCL3; DICER-LIKE 3; DCL4; DICER-LIKE 4; DD
MicroRNAs: Milk's epigenetic regulators
Keywords: epigenetic regulation; DNA methyltransferase 1; formula; milk; miRNA-148a; p53;
Hotair facilitates hepatic stellate cells activation and fibrogenesis in the liver
Keywords: Hotair; LncRNA HOX transcript antisense RNA; HSCs; hepatic stellate cells; PRC2; polycomb repressive complex 2; H3K27me3; histone H3-lysine27; DNMT1; DNA methyltransferase 1; α-SMA; alpha smooth muscle actin; Col1a1; alpha1(1) collagen; NcRNA; non-coding
Effects of Klotho on fibrosis and cancer: A renal focus on mechanisms and therapeutic strategies
Keywords: ACE; angiotensin converting enzyme; ADAM; a disintegrin and metalloproteinase; AKI; acute kidney injury; ANGII; angiotensin II; AT1; angiotensin II receptor type 1; AMPKα; AMP-activated protein kinase α; α-SMA; α-smooth muscle actin; CKD; chronic kidn
miR-140-5p regulates hypoxia-mediated human pulmonary artery smooth muscle cell proliferation, apoptosis and differentiation by targeting Dnmt1 and promoting SOD2 expression
Keywords: Pulmonary arterial hypertension; miR-140-5p; DNA methyltransferase 1; Superoxide dismutase 2
AMPK/Snf1 signaling regulates histone acetylation: Impact on gene expression and epigenetic functions
Keywords: ACAT1; acetoacetyl-CoA thiolase; ACC; acetyl-CoA carboxylase; AICAR; 5-aminoimidazole-4-carboxamide ribonucleoside; AMPK; AMP-activated protein kinase; ATAC; Ada-two-A-containing; BET; bromodomains and extra-terminal motif; BMAL1; PAS domain-containing pr
The association of DNA methyltransferase 1 gene polymorphisms with susceptibility to childhood acute lymphoblastic leukemia
Keywords: Acute lymphoblastic leukemia; DNA methyltransferase 1; Polymorphism; Susceptibility
Quercetin protects mouse liver against nickel-induced DNA methylation and inflammation associated with the Nrf2/HO-1 and p38/STAT1/NF-κB pathway
Keywords: Quercetin; Nickel; Inflammation; Nrf2; STAT1; Liver; ALT; alanine aminotransferase; AST; aspartate aminotransferase; DNMT1; DNA methyltransferase 1; HO-1; heme oxygenase-1; IL-1β; interleukin-1 beta; iNOS; inducible nitric oxide synthase; NF-κB; nuclear
Perinatal nicotine exposure suppresses PPARγ epigenetically in lung alveolar interstitial fibroblasts
Keywords: α-SMA; Alpha smooth muscle actin; ATII; Alveolar epithelial type II; Aza-CdR; 5-Aza-2â²-deoxycytidine; ChIP; Chromatin immunoprecipitation; DMSO; Dimethyl sulfoxide; DNMT1; DNA methyltransferase 1; LIFs; Lipofibroblasts; MSP; Methylation-specific-PCR; M
Non-coding RNA repertoires in malignant pleural mesothelioma
Keywords: AD; adenocarcinoma; ADARB2; RNA-specific adenosine deaminase, B2; aCGH; array comparative genomic hybridization; BAPE; benign asbestos-related pleural effusion; CCND1; cyclin D1; ceRNA; competing endogenous RNA; CREB; cAMP response element binding protein
Expression of DNMT1 in neural stem/precursor cells is critical for survival of newly generated neurons in the adult hippocampus
Keywords: DNA methyltransferase 1; Adult neurogenesis; DNA methylation; Neuronal survival; Neural stem cells;
New Experimental Models of Skin Homeostasis and Diseases
Keywords: SkinModel-CM software; Epidermal stem cells; DNA methyltransferase 1; Endoglin; Podoplanin; Genetically modified mice; Three-dimensional skin equivalents; Skin-humanized mice; Photodynamic therapyPrograma SkinModel-CM; Células madre epidérmicas; ADN metil
SOCS1 hypermethylation mediated by DNMT1 is associated with lipopolysaccharide-induced inflammatory cytokines in macrophages
Keywords: RAW264.7 mouse macrophage cell line; Suppressors of cytokine signaling1 (SOCS1); Hypermethylation; DNA methyltransferase1 (DNMT1); Pro-inflammatory cytokines; LPS; lipopolysaccharide; TNF-α; tumor necrosis factor-α; IL-6; interleukin 6; SOCS; suppressor
Methylglyoxal induces endoplasmic reticulum stress and DNA demethylation in the Keap1 promoter of human lens epithelial cells and age-related cataracts
Keywords: H2-DCFH-DA; 2â²,7â²-dichlorodihydrofluorescein diacetate; 5-Aza; 5-aza-2â²-deoxycytidine; 5-mC; 5-methylcytosine; ATF; activating transcription factor; AID; activation-induced deaminase; AGE; advanced glycation end-product; ARC; age-related cataract; A
DNA methylation: New therapeutic implications for hepatic fibrosis
Keywords: HSCs; hepatic stellate cells; ECMs; extracellular matrices; α-SMA; α-smooth muscle actin; TGF-β; transforming growth factor-β; PDGF; platelet-derived growth factor; DNMTs; DNA methyltransferases; DNMT1; DNA methyltransferase 1; 5-Aza-dC; 5-Aza-2â²-de
Epigallocatechin-3-gallate up-regulates tumor suppressor gene expression via a reactive oxygen species-dependent down-regulation of UHRF1
Keywords: DNMT1; DNA methyltransferase1; EGCG; epigallocatechin-3-gallate; ROS; reactive oxygen species; UHRF1; Ubiquitin-like PHD, Ring finger 1; DNA methyltransferase 1; Epigallocatechin-3-gallate; P16INK4A; Tumor suppressor gene; Ubiquitin-like containing PHD an
The H19 induction triggers trophoblast lineage commitment in mouse ES cells
Keywords: ESCs; embryonic stem cells; ICM; inner cell mass; PE; primitive ectoderm; TE; trophectoderm; Parp-1; poly(ADP-ribose) polymerase 1; Plf1; proliferin 1; Dnmt1; DNA methyltransferase 1; Gapdh; glyceraldehyde 3-phosphate dehydrogenase; Tc; tetracycline; Zeo;
Development of a rapid and sensitivity magnetic chemiluminescence immunoassay for DNA methyltransferase 1 in human serum
Keywords: DNA methyltransferase 1; Biomarker; Chemiluminescence immunoassay; Magnetic particles; Human serum;
Ultraviolet B enhances DNA hypomethylation of CD4+ T cells in systemic lupus erythematosus via inhibiting DNMT1 catalytic activity
Keywords: DNA methylation; DNA methyltransferase 1; Lupus erythematosus; Systemic; Ultraviolet
Epigallocatechin gallate and sulforaphane combination treatment induce apoptosis in paclitaxel-resistant ovarian cancer cells through hTERT and Bcl-2 down-regulation
Keywords: EGCG; epigallocatechin gallate; SFN; sulforaphane; PARP; poly(ADP-ribose) polymerase; HDAC; histone deacetylase; DMSO; dimethyl sulfoxide; DNMT1; DNA methyltransferase 1; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; PI; propidium iod
Phosphorylation of human DNMT1: Implication of cyclin-dependent kinases
Keywords: Cyclin-dependent kinase; DNA methyltransferase 1; Protein phosphorylation; DNA methylation
A glycobiology review: Carbohydrates, lectins and implications in cancer therapeutics
Keywords: Glycobiology review; Carbohydrates; Lectins; Cancer therapeutics; Cancer glycans; APC; antigen presenting cell; B4GALNT2; β-1,4-N-acetyl-galactosaminyltransferase; CDKL5; cyclin-dependent kinase-like 5; CNS; central nervous system; Con A; concanavalin A;
TSA-induced DNMT1 down-regulation represses hTERT expression via recruiting CTCF into demethylated core promoter region of hTERT in HCT116
Keywords: DNA methylation; DNA methyltransferase 1; Epigenetic regulation; Human telomerase reverse transcriptase; Trichostatin A;