Epigallocatechin gallate and sulforaphane combination treatment induce apoptosis in paclitaxel-resistant ovarian cancer cells through hTERT and Bcl-2 down-regulation

► Epigallocatechin gallate (EGCG) plus sulforaphane (SFN) inhibit resistant cancer. ► This inhibition of resistant ovarian cancer cells causes G2/M arrest and apoptosis. ► EGCG and SFN treatment causes DNA damage to the ovarian cancer cells. ► These treatments also decrease hTERT and Bcl-2 expression in ovarian cancer cells. ► EGCG and SFN are effective in treating paclitaxel-resistant ovarian cancer cells.