Keywords: 4- Shogaol (PubChem CID: 9794897); 6- Shogaol (PubChem CID: 5281794); Apigenin (PubChem CID: 5280443); Berberine (PubChem CID: 2353); Bergamottin (PubChem CID: 5471349); Caffeic acid (PubChem CID: 689043)Capsaicin (PubChem CID: 1548943); Cardamonin (PubCh
مقالات ISI (ترجمه نشده)
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Keywords: ACC1; acetyl-CoA carboxylase 1; AHCY; S-adenosylhomocysteine hydrolase; AMPK; AMP-activated protein kinase; ATGL; adipose triglyceride lipase; BHMT; betaine homocysteine methyltransferase; CD36; fatty acid translocase; CPT1α; carnitine palmitoyltransfera
Keywords: MGE; medial ganglionic eminence; POA; pre-optic area; CGE; caudal ganglionic eminence; GABA; Glutamate; DNMT1; DNA methylation; Histone modifications;
Keywords: Oxysterols; Cancer; Polymorphism; Risk; Genetics; Cholesterol; 25(OH)D; 25-hydroxyvitamin D; ABC; ATP-binding cassette; AEBS; antiestrogen-binding site; BC; breast cancer; BCR; biochemical recurrence; CETP; cholesteryl ester transfer protein; CH25H; chole
Keywords: TME; tumour microenvironment; PD-1; programmed cell death 1; PD-L1; programmed death ligand 1; PD-L2; programmed death ligand 2; PTMs; post-translational histone modifications; DNMTi; DNA methyltransferase inhibitor; HDACi; histone deacetylase inhibitor;
Keywords: â¢OH; hydroxyl radical; 2,2-BP; 2,2-bipyridyl; ABC; ATP-binding cassette; AIF; apoptosis-inducing factor; AMPK; AMP-activated protein kinase; AMPKK; AMPK kinase; ANT; adenine nucleotide translocase; AP-1; activator protein 1; Apaf-1; protease activating
Keywords: 2-DG; 2-deoxyglucose; 2-HG; 2-hydroxyglutarate; 5mC; 5-methlycystosine; ACACA; acetyl-CoA carboxylase; AML; acute myeloid leukemia; AMPK; adenosine monophosphate-activated protein kinase; ATP; adenosine triphosphate; ALDH; aldehyde dehydrogenase; ADCs; an
Keywords: HG; Hyperglycemia; DM; Diabetes mellitus; MM; Metabolic memory; DM/MM; Diabetes mellitus/Metabolic Memory; GLUT; Glucose transporter; ROS; Reactive oxygen species; VEGF; Vascular endothelial growth factor; STZ; Streptozotocin; AGE; Advanced glycation end
Keywords: Genomic imprinting; Lipids; Triacylglycerols; Mitochondria; DNMT1;
Keywords: SAXS, small-angle X-ray scattering; SIC, selected-ion chromatogramDNA methylation; DNMT1; epigenetics; allosteric regulation; autoinhibition
Keywords: NAFLD; Non-alcoholic fatty liver disease; dG-TAM; (E)-α-(deoxyguanosin-N2-yl)-tamoxifen; dG-DesMeTAM; (E)-α-(deoxyguanosin-N2-yl)-N-desmethyltamoxifen; ALT; alanine transaminase; AST; aspartate transaminase; LDH; lactate dehydrogenase; α-SMA; α-smooth
Keywords: A; adenine; AFLP; amplified fragment length polymorphism; AHR; aryl-hydrocarbon receptor; As; arsenic; B[a]P; benzo[a]pyrene; BPA; Bisphenol A; C; cytosine; Cd; cadmium; CpA; cytosine-phosphate-adenine; CpG; cytosine-phosphate-guanine; Cr; chromium; C
Keywords: AHR; aryl hydrocarbon receptor; AIP; aryl hydrocarbon receptor interacting protein; BMP-4; bone morphogenetic protein 4; CDK; cyclin-dependent kinases; CDKN1A; cyclin-dependent kinase inhibitor 1A; CDKN1B; cyclin-dependent kinase inhibitor 1B; CDKN2A; cyc
Keywords: DNMT1; Cancer; Non-nucleosides; Drug development
Keywords: Physical exercise; Repeated restraint stress; DNA methylation; Dnmt1; Epigenetics
Dietary betaine supplementation in hens modulates hypothalamic expression of cholesterol metabolic genes in F1 cockerels through modification of DNA methylation
Keywords: ACAT1; acetyl-CoA cholesterol acyltransferase 1; APOA1; apolipoprotein A1; BHMT; betaine homocysteine methyltransferase; BBB; blood brain barrier; CYP46A1; cholesterol 24-hydroxylase A 1; DNMT1; DNA methyltransferase 1; DNMT3A; DNA methyltransferase 3 A;
Repression of Dok7 expression mediated by DNMT1 promotes glioma cells proliferation
Keywords: Glioma; Dok7; 5-Aza; DNMT1;
MiR-139-5p suppresses osteosarcoma cell growth and invasion through regulating DNMT1
Keywords: Osteosarcoma; miR-139-5p; DNMT1; Migration; Invasion;
Homocysteine inhibits endothelial progenitor cells proliferation via DNMT1-mediated hypomethylation of Cyclin A
Keywords: Homocysteine; Endothelial progenitor cells; Cyclin A; DNA methylation; DNMT1;
HBP1 phosphorylation by AKT regulates its transcriptional activity and glioblastoma cell proliferation
Keywords: DNMT1; DNA-methyltransferase 1; FOXO; Forkhead box O transcription factors; GST; glutathione S-transferase; HBP1; HMG-box protein 1; HEK; human embryonic kidney; HMG; high mobility group; HPLC; high performance liquid chromatography; KD; kinase dead; MS;
CCRK is a novel signalling hub exploitable in cancer immunotherapy
Keywords: 9G8; serine and arginine rich splicing factor 7; AKT; AKT serine/threonine kinase; AR; androgen receptor; ARE; androgen response element; ARG1; arginase 1; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and rad3-related protein; BMDC; mous
Matrix stiffness determines the phenotype of vascular smooth muscle cell in vitro and in vivo: Role of DNA methyltransferase 1
Keywords: Arterial stiffening; DNA methylation; DNMT1; Smooth muscle cell calcification; Cellular stiffening;
Kindlin-2 interacts with and stabilizes DNMT1 to promote breast cancer development
Keywords: Kindlin-2; Breast cancer; DNMT1; E-cadherin;
Regulation of cancer immune escape: The roles of miRNAs in immune checkpoint proteins
Keywords: Immune checkpoint proteins (ICPs); miRNAs; Cancer immune escape; Antigen-MHC; antigen-major histocompatibility complex; ICPs; immune checkpoint proteins; 3â²UTR; 3â² untransltated region; PD-1; programmed cell death protein; Tregs; regulatory T cells; H
DNMT1 is associated with cell cycle and DNA replication gene sets in diffuse large B-cell lymphoma
Keywords: Diffuse large B-cell lymphoma; DNMT1; Cell cycle; DNA replication; Gene set enrichment analysis;
Maternal betaine administration modulates hepatic type 1 iodothyronine deiodinase (Dio1) expression in chicken offspring through epigenetic modifications
Keywords: AHCYL1; adenosylhomocysteinase-like 1; BHMT; betaineâhomocysteineâSâmethyltransferase; DNMT1; DNA methyltransferase 1; Dio1; type 1 iodothyronine deiodinase; Dio2; type 2 iodothyronine deiodinase; Dio3; type 3 iodothyronine deiodinase; LAT1; L-type
Amentoflavone induces apoptosis and suppresses glycolysis in glioma cells by targeting miR-124-3p
Keywords: Amentoflavone; Glioma; Apoptosis; Glycolysis; miR-124-3p; DNMT1;
Overexpression of DNMT1 leads to hypermethylation of H19 promoter and inhibition of Erk signaling pathway in disuse osteoporosis
Keywords: Disuse osteoporosis; DNA methylation; DNMT1; Long-noncoding RNA-H19, Erk-MAPK signaling pathway;
Fresh red raspberry phytochemicals suppress the growth of hepatocellular carcinoma cells by PTEN/AKT pathway
Keywords: RRE; red raspberry extract; CCK8; cell counting Kit-8; DNMT1; DNA methyltransferase 1; PTEN; phosphatase and tensin homologue deleted on chromosome 10; HCC; hepatocellular carcinoma; HPLC; high performance liquid chromatography; LC-MS; liquid chromatogr
Antagonistic activities of miR-148a and DNMT1: Ectopic expression of miR-148a impairs DNMT1 mRNA and dwindle cell proliferation and survival
Keywords: Micro RNA; miRNA; DNA methyltransferase; DNMT1; 3-(4, 5-Dimethylthiazol-2-yl)-2, 5-Diphenyltetrazolium Bromide; MTT; Extracellular matrix; ECM; Chromatin immunoprecipitation; ChIP; miRNA-148; miR-148; Quantitative real time polymerase chain reaction; qRT-
TRPM2 mediates mitochondria-dependent apoptosis of melanocytes under oxidative stress
Keywords: ROS; reactive oxygen species; MMP; mitochondrial membrane potential; TRPM2; transient receptor potential cation channel subfamily M member 2; H2O2; hydrogen peroxide; NHMs; Normal human melanocytes; NAC; N-acety-L-cysteine; Ru360; Ruthenium 360; 5-aza-dC;
HOTAIR-mediated reciprocal regulation of EZH2 and DNMT1 contribute to polyphyllin I-inhibited growth of castration-resistant prostate cancer cells in vitro and in vivo
Keywords: PPI; polyphyllin I; CRPC; castration-resistant prostate cancer; EZH2; Zeste homolog 2; DNMT1; DNA methyltransferase 1; HOTAIR; HOX transcript antisense RNA; ADT; androgen deprivation therapy; NF-κB; nuclear factor-kappaB; lncRNA; Long non-coding RNA; DNM
Presence of a consensus DNA motif at nearby DNA sequence of the mutation susceptible CG nucleotides
Keywords: TS; tumor suppressor; DNMT1; DNA methyltransferase 1; NTDs; nucleotides; AAs; amino acids; RMSD; root mean square deviation; MD; molecular dynamics; HB; hydrogen bond; PWM; position weight matrix; Mutation; Epigenetics; CpG islands; Tumor suppressors; Onc
STAT3-mediated epigenetic silencing of FOXP3 in LADA T cells is regulated through HDAC5 and DNMT1
Keywords: LADA; STAT3; HDAC5; DNMT1; FOXP3;
Downregulation of microRNA-370 in esophageal squamous-cell carcinoma is associated with cancer progression and promotes cancer cell proliferation via upregulating PIN1
Keywords: EC; esophageal cancer; ESCC; esophageal squamous-cell carcinoma; EA; esophageal adenocarcinoma; PIN1; Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; RUX3; runt-related transcription factor 3; UTR; untranslated region; qRT-PCR; quantitative real-t
Long non-coding RNAs regulation in adipogenesis and lipid metabolism: Emerging insights in obesity
Keywords: lncRNAs; Obesity; White adipogenesis; Brown adipocyte differentiation; Lipid metabolism; Therapeutics; WAT; white adipose tissue; BAT; brown adipose tissue; Pparg; peroxisome proliferator-activated receptor γ; Cebpa; CCAAT/enhancer binding protein α; Fa
A Trichostatin A (TSA)/Sp1-mediated mechanism for the regulation of SALL2 tumor suppressor in Jurkat T cells
Keywords: AP4; Activating Protein 4; BAX; Bcl-2-associated X protein; Brd4; Bromodomain-containing protein 4; Brg1; Brahma-related gene-1; C2H2; Cys2-His2 zinc finger; CBP; CREB-binding protein; CDKN2A; Cyclin-Dependent Kinase Inhibitor 2A gene; CDKN1A; Cyclin-Depe
DNA methyltransferase 1 mediated aberrant methylation and silencing of SHP-1 gene in chronic myelogenous leukemia cells
Keywords: CML; chronic myelogenous leukemia; DNMT; DNA methyltransferase; PCR; polymerase chain reaction; BSP; bisulfite sequencing PCR; MSP; methylation-specific PCR; SHP-1; Methylation; Gene silencing; DNMT1;
Multi-PK antibodies: Powerful analytical tools to explore the protein kinase world
Keywords: 2D-PAGE; two-dimensional polyacrylamide gel electrophoresis; CaMK; Ca2+/calmodulin-dependent protein kinase; CDKL5; cyclin-dependent kinase-like 5; CNBr; cyanogen bromide; DCLK; double-cortin like protein kinase; Dnmt1; DNA methyltransferase 1; FAK; focal
Sirt7 stabilizes rDNA heterochromatin through recruitment of DNMT1 and Sirt1
Keywords: Sirt7; Sirt1; DNMT1; rDNA repeats; Heterochromatin; Nucleolus;
Assay of DNA methyltransferase 1 activity based on uracil-specific excision reagent digestion induced G-quadruplex formation
Keywords: Electrochemical biosensor; DNMT1; USER; G-quadruplex;
DNA methylation and histone deacetylation regulating insulin sensitivity due to chronic cold exposure
Keywords: Chronic cold exposure; DNA methylation; Histone deacetylation; Insulin resistance; Mitochondrion; CpG; cytosine-phosphate-guanine; cytC; cytochrome C; Dnmt1; DNA methyltransferase 1; DNMT3a; DNA methyltransferase 3a; FPG; fasting plasma glucose; FINS; fas
TGF-β-mediated repression of MST1 by DNMT1 promotes glioma malignancy
Keywords: WHO; World Health Organization; MST1; Mammalian Sterile 20 Like Kinase 1; NES; nuclear export sites; DNMTs; DNA methyltransferases; Glioma; MST1; DNMT1;
Modulations of DNMT1 and HDAC1 are involved in the OTA-induced cytotoxicity and apoptosis in vitro
Keywords: Ochratoxin A; DNMT1; HDAC1; Cytotoxicity; Apoptosis;
Original articlePhyscion 8-O-β-glucopyranoside suppresses the metastasis of breast cancer in vitro and in vivo by modulating DNMT1
Keywords: Physcion 8-O-β-glucopyranoside; Breast cancer; Metastasis; DNMT1; Sp1; AMPK;
Icaritin induces mitochondrial apoptosis by up-regulating miR-124 in human oral squamous cell carcinoma cells
Keywords: Icaritin; Apoptosis; MiR-124; DNMT1; Sp1;
DNMT1 is predictive of survival and associated with Ki-67 expression in R-CHOP-treated diffuse large B-cell lymphomas
Keywords: Diffuse large B-cell lymphoma; DNMT1; survival; Ki-67; BCL6;
Dnmt1 activity is dispensable in δ-cells but is essential for α-cell homeostasis
Keywords: Cre; Cre recombinase; Dnmt1; DNA methyltransferase 1; Dox; doxycycline; DT; diphtheria toxin; DTR; diphtheria toxin receptor; Ezh2; enhancer of zeste homolog 2; Gcg; glucagon; IAP; intracisternal A-particle; Ins; insulin; m-o; month-old; PRC; polycomb rep
Dynamics and Context-Dependent Roles of DNA Methylation
Keywords: mES; murine embryonic stem; DNMT; DNA methyltransferase; DNMT3A; DNA methyltransferase 3A; DNMT3B; DNA methyltransferase 3B; DNMT1; DNA methyltransferase 1; H3K36me3; histone H3 lysine-36 trimethylation; ES; embryonic stem; UHRF1; ubiquitin-like with PHD
LncRNA-SNHG1 contributes to gastric cancer cell proliferation by regulating DNMT1
Keywords: Gastric cancer; Long-chain non-coding RNA SNHG1; Prognosis; DNMT1;