دانلود مقالات ISI درباره Dock8 + ترجمه فارسی

تشخیص مبتنی بر جریان سیاتومتر بیماری های اولیه کمبود ایمنی

Flow cytometry-based diagnosis of primary immunodeficiency diseases

Keywords: Flow cytometry; Intracellular protein; Monoclonal antibody; Primary immunodeficiency disease; Surface protein; ADA; adenosine deaminase; ALPS; autoimmune lymphoproliferative syndrome; APECED; autoimmune polyendocrinopathy-candidiasis-ectodermal dystrop

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

متخصص کمبود ایمنی در ارتباط با جهش های مرتبط با سیتوکینیس 8: تجربه تک مرکز از هند

Dedicator of cytokinesis 8 mutation related combined immune deficiency: A single centre experience from India

Keywords: Combined immunodeficiency; DOCK8; Children;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

شیوع و الگوی اختلالات پوستی در خدمات اضطراری کودکان

Prevalence and pattern of dermatological disorders in the pediatric emergency service

Keywords: CMCC; chronic mucocutaneous candidiasis; DOCK8; dedicator of cytokinesis 8; ER; emergency room; VZV; varicella zoster virus; Curriculum development; Dermatology; Emergency care; Pediatrics; Primary care education; Rash;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

پیشرفت در ایمنی اولیه و بالینی در سال 2016

Advances in basic and clinical immunology in 2016

Keywords: Immunology; primary immunodeficiency; whole-exome sequencing; hematopoietic stem cell transplantation; common variable immunodeficiency; severe combined immunodeficiency; hyper-IgE syndrome; AIP1; Actin-interacting protein 1; APDS; Activated PI3Kδ syndro

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

زیست شناسی سلول های قاتل طبیعی با سندرم های کمبود ابتدایی در انسان روشن می شود

Natural killer cell biology illuminated by primary immunodeficiency syndromes in humans

Keywords: ADCC; antibody-dependent cell-mediated cytotoxicity; AP3; adaptor protein 3; CHS; Chediak-Higashi syndrome; CMV; cytomegalovirus; CNKD; classical natural killer cell deficiency; CrkL; chicken tumor virus number 10 regulator of kinase-like; CTL; cytotoxi

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2017 سفارش ترجمه

تقاطع خودکارآموزی و کمبود ایمنی: درسهایی از ویژگیهای پلی¬گنیک و نقایص مونوژنیک

The crossroads of autoimmunity and immunodeficiency: Lessons from polygenic traits and monogenic defects

Keywords: Autoimmunity; primary immunodeficiency diseases; B cells; T cells; AID; Activation-induced cytidine deaminase; AIHA; Autoimmune hemolytic anemia; AIRE; Autoimmune regulator; ALPS; Autoimmune lymphoproliferative disease; ANA; Anti-nuclear autoantibody; AP

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

بروز ابتلا به کمبود ایمنی

Primary immunodeficiency update

Keywords: AD; autosomal dominant; AD-HIES; autosomal dominant hyper-immunoglobulin E syndrome; AR; autosomal recessive; BMD; bone mineral density; CMC; chronic mucocutaneous candidiasis; DOCK8; dedicator of cytokinesis 8; EBV; Epstein-Barr virus; FOXP3; forkhea

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

پیشرفت در ایمنی اولیه و بالینی در سال 2014

Advances in basic and clinical immunology in 2014

Keywords: Immunology; primary immunodeficiency; dedicator of cytokinesis 8; HIV1; recombination-activating gene 1; intravenous immunoglobulin; common variable immunodeficiency; severe combined immunodeficiency; newborn screening; ADA; Adenosine deaminase; ApoE; Apo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

بینش کمبود ایمنی اولیه از میکروسکوپ کمی

Insights into primary immune deficiency from quantitative microscopy

Keywords: Primary immune deficiency; microscopy; cell biology; cytoskeleton; host defense; AP3; Adaptor protein 3; Arp2/3; Actin-related proteins 2 and 3; CDC42; Cell division cycle 42; CGD; Chronic granulomatous disease; CHS; Chediak-Higashi syndrome; CTL; Cytotox

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

بروز ابتلا به کمبود ایمنی

Primary immunodeficiency update

Keywords: ADA; adenosine deaminase; AIRE; autoimmune regulator; AML; acute myeloid leukemia; APECED; autoimmune polyendocrinopathy, candidiasis, and ectodermal dysplasia; APLAID; autoinflammation and PLCγ2-associated antibody deficiency and immune dysregulation; A

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

تغییرات جسمی در تلقیح از سیتوکینز 8 کمبود ایمنی، فنوتیپ بیماری را مدوله می کند

Somatic reversion in dedicator of cytokinesis 8 immunodeficiency modulates disease phenotype

Keywords: Dedicator of cytokinesis 8; reversion; somatic repair; recombination; gene conversion; intragenic single crossover; T cell; natural killer cell; allergy; immunodeficiency; DOCK8; Dedicator of cytokinesis 8; HCT; Hematopoietic cell transplantation; NK; Na

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

عواملی از مبادله فاکتور در مهاجرت سلولی و بیماری

Dock-family exchange factors in cell migration and disease

Keywords: Dock180; Dock1; Dock2; Dock3; Dock4; Dock5; Dock6; Dock7; Dock8; Dock9; Dock10; Dock11; Zizimin; DHR2; Rac1; Cdc42; Adhesion; Migration; Cancer; Exchange factor; Rho GTPase; Osteoclast; Amoeboid; GPCR; Integrin; Synapse;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

نقصان تجمع اکتین در عملکرد بیماران مبتلا به طبیعی قاتل طبیعی در بیماران مبتلا به کمبود سیتوکینزی 8 اختلال ایجاد میکند

Defective actin accumulation impairs human natural killer cell function in patients with dedicator of cytokinesis 8 deficiency

Keywords: DOCK8 deficiency; natural killer cells; actin; cytotoxicity; immunologic synapse; Cdc42; Cell division cycle 42; DOCK8; Dedicator of cytokinesis 8; F-actin; Filamentous actin; HIES; Hyper-IgE syndrome; IS; Immunologic synapse; MTOC; Microtuble organizing

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

IL-21 alleviates allergic asthma in DOCK8-knockout mice

Keywords: DOCK8 gene; Allergic asthma; Ovalbumin; Murine model; IL-21; rmIL-21; recombinant mouse interleukin-21; DOCK8; dedicator of cytokinesis 8; STAT3; signal transducer and activator of transcription 3; TYK2; tyrosine kinase 2; DIDS; DOCK8 immunodeficiency syn

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Diagnosis of DOCK8 deficiency using Flow cytometry Biomarkers: an Egyptian Center experience

Keywords: DOCK8; pSTAT3; Th17; AR-HIES; Flow cytometry;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

DOCK8 and STAT3 dependent inhibition of IgE isotype switching by TLR9 ligation in human B cells

Keywords: Hyper IgE Syndrome; IgE synthesis; CpG; DOCK8; STAT3;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

DOCK8 deficiency: Insights into pathophysiology, clinical features and management

Keywords: Actin; CDC42; Combined immunodeficiency; Dedicator of cytokinesis; DOCK2; DOCK8; Hyper IgE syndrome; Primary immunodeficiency; RAC1; STAT3; AR-HIES; autosomal recessive hyper IgE syndrome; AD-HIES; autosomal dominant hyper IgE syndrome; CDC42; cell divisi

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2017 سفارش ترجمه

Brief CommunicationHypomorphic function and somatic reversion of DOCK8 cause combined immunodeficiency without hyper-IgE

Keywords: CFSE; Carboxyfluorescein diacetate, succinimidyl ester; DHR1/2; DOCK homology region; DOCK8; Dedicator of cytokinesis 8; EBV; Epstein-Barr-Virus; HC; Healthy control; Mut; Mutated DOCK8 transcript (referring to c.6019dupT); PBMC; Peripheral blood mononu

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Interstitial 9p24.3 deletion involving only DOCK8 and KANK1 genes in two patients with non-overlapping phenotypic traits

Keywords: 9p24.3 deletion; DOCK8; KANK1; Trigonocephaly; Array-CGH;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Dock8 interacts with Nck1 in mediating Schwann cell precursor migration

Keywords: Dock8; Nck1; PDGF; Schwann cell precursor; Migration

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

The transcriptional programs of iNKT cells

Keywords: α-GalCer; α-galactosylceramide; BTB-POZ-ZF; broad complex, tramtrack, bric-a-brac or poxvirus and zinc finger; CCR2; C-C chemokine receptor type 2; CCR10; C-C chemokine receptor type 10; ChIP-seq; chromatin immunoprecipitation with deep sequencing

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Brief CommunicationFlow cytometry biomarkers distinguish DOCK8 deficiency from severe atopic dermatitis

Keywords: DOCK8; dedicator of cytokinesis-8; AD; atopic dermatitis; TEMRA; exhausted effector memory cells; MZ; marginal zone.; DOCK8;; Hyper-IgE;; Atopic dermatitis;; T cell;; B cell;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Successful interferon-alpha 2b therapy for unremitting warts in a patient with DOCK8 deficiency

Keywords: DOCK8; dedicator of cytokinesis 8 deficiency; DT; diphtheria and tetanus; EBV; Epstein-Barr virus; HIES; hyper-immunoglobulin E; IFN-α 2b; interferon-alpha 2b; MMR; measles, mumps and rubella; TLR; Toll-like receptors; DOCK8 deficiency; Hyper -immunogl

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Expansion of CCR4 + activated T cells is associated with memory B cell reduction in DOCK8-deficient patients

Keywords: Hyper-IgE syndrome; DOCK8; Th2 commitment; Recent thymic emigrants; Memory B cells;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Immune deficiencies, infection, and systemic immune disordersDedicator of cytokinesis 8-deficient patients have a breakdown in peripheral B-cell tolerance and defective regulatory T cells

Keywords: Dedicator of cytokinesis 8; autoimmunity; B-cell tolerance; regulatory T cells; ANA; Anti-nuclear antibody; BAFF; B-cell activating factor; BCR; B-cell receptor; DOCK8; Dedicator of cytokinesis 8; dsDNA; Double-stranded DNA; FOXP3; Forkhead box P3; HD; He

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Autosomal recessive phosphoglucomutase 3 (PGM3) mutations link glycosylation defects to atopy, immune deficiency, autoimmunity, and neurocognitive impairment

Keywords: Atopy; immune deficiency; hyper-IgE; neurocognitive impairment; phosphoglucomutase 3; glycosylation; allergy; autoimmunity; APC; Allophycocyanin; CDG; Congenital disorder of glycosylation; CFSE; Carboxyfluorescein succinimidyl ester; DOCK8; Dedicator of c

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

Sphingosine-1-phosphate receptors control B-cell migration through signaling components associated with primary immunodeficiencies, chronic lymphocytic leukemia, and multiple sclerosis

Keywords: Sphingosine-1-phosphate; B cells; migration; autoimmunity; circulation; fingolimod; FTY720; primary immunodeficiencies; ALL; Acute lymphoblastic leukemia; B-CLL; B-cell chronic lymphocytic leukemia; BCR; B-cell receptor; BFP; Blue fluorescent protein; BTK

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2014 سفارش ترجمه

Brief CommunicationAberrant humoral immune reactivity in DOCK8 deficiency with follicular hyperplasia and nodal plasmacytosis

Keywords: Hyper-IgE; DOCK8; Molluscum contagiosum; HSCT; Antigen-specificity; Memory response;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

B-cell biology and development

Keywords: B cell; B lymphocyte; immunodeficiency; development; humoral immunity; autoimmunity; tolerance; AID; Activation-induced cytidine deaminase; APRIL; A proliferation-inducing ligand; BAFF; B-cell activator of the TNF-α family (aka BLYS); BAFF-R; BAFF recept

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

TH17 deficiency in human disease

Keywords: TH cells; Candida species; fungi; TH17 cell; pathogen-recognition receptors; cytokines; transcription factors; differentiation; chronic mucocutaneous candidiasis; AD; Autosomal dominant; AIRE; Autoimmune regulator; APECED; Autoimmune polyendocrinopathy-

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Warts and all: Human papillomavirus in primary immunodeficiencies

Keywords: Immunodeficiency; human papillomavirus; warts; squamous; carcinoma; dysplastic; ADA; Adenosine deaminase; A-T; Ataxia-telangiectasia; ATM; Ataxia-telangiectasia mutated gene; CD40L; CD40 ligand; CMV; Cytomegalovirus; CVID; Common variable immunodeficiency

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2012 سفارش ترجمه

Generalized verrucosis: A review of the associated diseases, evaluation, and treatments

Keywords: CD4+ lymphocytopenia; epidermodysplasia verruciformis; extensive human papillomavirus; extensive human papillomavirus infection; extensive verrucosis; extensive warts; generalized verrucae treatment; generalized verrucosis; generalized warts; human papill

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2012 سفارش ترجمه

Deficient T Cell Receptor Excision Circles (TRECs) in autosomal recessive hyper IgE syndrome caused by DOCK8 mutation: Implications for pathogenesis and potential detection by newborn screening

Keywords: Hyper-IgE; Dermatitis; DOCK8; Job sdynrome; Immunodeficiency; TRECs

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Clinical, immunological and genetic features in Taiwanese patients with the phenotype of hyper-immunoglobulin E recurrent infection syndromes (HIES)

Keywords: Hyper IgE recurrent infection syndromes (HIES); STAT3; TYK2; DOCK8; Primary immunodeficiency diseases (PIDs); Taiwan; Chinese;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Primary immunodeficiency diseases associated with increased susceptibility to viral infections and malignancies

Keywords: Immunodeficiency; viral infection; malignancies; X-linked lymphoproliferative syndrome; AR-HIES; Autosomal recessive hyper-IgE syndrome; CVID; Common variable immunodeficiency; DDR; DNA damage response; DOCK8; Dedicator of cytokinesis 8; EV; Epidermodyspl

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2011 سفارش ترجمه

Large deletions and point mutations involving the dedicator of cytokinesis 8 (DOCK8) in the autosomal-recessive form of hyper-IgE syndrome

Keywords: Autosomal recessive hyper-IgE syndrome; human gene mutation; DOCK8; primary immunodeficiency; molluscum contagiosum; recurrent infection; T cells; TH17 cells; eosinophils; IgE regulation; copy number variations; genomic deletions; AR; Autosomal-recessive;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2009 سفارش ترجمه

Dedicator of cytokinesis 8 is disrupted in two patients with mental retardation and developmental disabilities

Keywords: Subtelomere; Mental retardation; Chromosome translocation; DOCK8; Autosome

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه