Keywords: AOB; accessory olfactory bulb; MePD; posterodorsal medial amygdala; MePV; posteroventral medial amygdala; Me; medial amygdala; VNO; vomeronasal organ; VNS; vomeronasal neural system; MeA; anterior amygdala; MOB; main olfactory bulb; AAV; adeno-associated
مقالات ISI (ترجمه نشده)
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Keywords: Dopamine; Motivation; DREADD; TH-Cre rats; Ventral tegmental area; Substantia nigra;
Keywords: BLA; basolateral amygdaloid nucleus, anterior part; BLP; basolateral amygdaloid nucleus, posterior part; Ce; central amygdaloid nucleus; Cg1; cingulate cortex, area 1; CRF; corticotropin-releasing factor; DR; dorsal raphe nucleus; DRC; dorsal raphe nucleu
Keywords: Temporal lobe epilepsy; Pharmaco-genetic; Parvalbumin neurons; Pyramidal neurons; ADD; Afterdischarge duration; ADT; Afterdischarge threshold; AEDs; Anti-epileptic drugs; ACSF; Artificial cerebrospinal fluid; CNO; Clozapine-N-oxide; DREADD; Designer Recep
Keywords: AA; amino acid; Aβo; oligomeric β-amyloid; Aβ; β-amyloid; AD; Alzheimer's disease; α7nAChR; α7 nicotinic acetylcholine receptor; ALS; amyotrophic lateral sclerosis; APLP1; amyloid beta precursor-like protein 1; APP; amyloid precursor protein; β-A
Keywords: L-DOPA induced dyskinesias; Parkinson's disease; Animal models; Chemogenetics; DREADD; Cholinergic interneurons; AAV; Transgenic rats; Indirect pathway; Direct pathway;
Keywords: BNST; VTA; CPP; Ethanol; DREADD; HSV;
Keywords: ASD; autism spectrum disorders; BTBR; BTBR T+Itpr3tf/J mouse strain; cKO; conditional knockout; CNS; central nervous system; CNTNAP2; contactin-associated protein-like 2; DREADD; designer receptors exclusively activated by designer drugs; DSM-5; Diagnosti
Keywords: ABC; avidin-biotin complex; AD; anterodorsal thalamic nucleus; AM; anteromedial thalamic nucleus; AV; anteroventral thalamic nucleus; DREADD; designer receptors exclusively activated by designer drugs; EGTA; ethylene glycol-bis(β-aminoethyl ether)-N,N,
Keywords: ACh; acetylcholine; ACSF; artificial cerebrospinal fluid; ARAS; ascending reticular activating system; BF; basal forebrain; BRET; bioluminescence resonance energy transfer; CFP; cyan fluorescent protein; ChAT; choline acetyltransferase; ChR2; channelrhodo
Keywords: ACh; acetylcholine; ACSF; artificial cerebrospinal fluid; AlstR; allatostatin receptor; Amyg; amygdala; ANOVA; analysis of variance; ATD; double-positive mouse receiving drug; BCIP; 5-bromo-4-chloro-3â²-indolyphosphate; CaMKII; calmodulin activated prote
Keywords: ADHD; attention deficit/hyperactivity disorder; DICE-K; doxycycline-inhibited circuit-exocytosis knockdown; DREADD; designer receptors exclusively activated by designer drugs; DRN; dorsal raphe nucleus; mPFC; medial prefrontal cortex; OB; olfactory bulbec
Keywords: Alcohol; Frontal cortex; Excitotoxic lesion; DREADD; LOFC; lateral orbitofrontal cortex; CIE; chronic intermittent ethanol; CNO; clozapine-N-oxide; DREADD; designer receptor exclusively activated by designer drug; GFP; green fluorescent protein; mPFC; med
Keywords: AAV; adeno-associated virus; Cav; voltage-gated calcium channel; CCD; conventional drug discovery; CNS; central nervous system; CRISPR/Cas9; clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9; DRG; dorsal root ganglion;
Keywords: DREADD; CNO; Chemogenetic; Kindling; Amygdala; Seizure; Rat;
Keywords: ACC; Anterior Cingulate Cortex; BLA; Baso-Lateral Amygdala; DLS; Dorsolateral Striatum; DMS; Dorsomedial; IL; Infra-Limbic Cortex; lOFC; Lateral Orbitofrontal Cortex; MD; mediodorsal thalamus; mOFC; Medial Orbitofrontal Cortex; mPFC; medial prefrontal cor
Keywords: Bed nucleus of the stria terminalis (BNST); vBNST; dBNST; Amygdala; Place preference; CPP; Ethanol; Alcohol; hM4Di; DREADD; RASSL; Chemogenetic; c-Fos; Clozapine-N-oxide (CNO); DBA/2J; Lesion; Inactivation; Microinfusion; Microinjection;
Keywords: Orexin; Hypothalamus; Pharmacogenetics; Feeding; Metabolism; AAV; adeno-associated virus; Arc; arcuate nucleus; CNO; clozapine-N-oxide; DREADD; designer receptors exclusively activated by designer drugs; DTA; diphtheria toxin fragment A; ICV; intracerebro
Keywords: AAV; adeno-associated virus; aRNB; asymmetric reversible neurotransmission blocking; CB1; cannabinoid receptors type 1; CPP; conditioned place preference; DA; dopamine; DOX; doxycycline; DREADD; designer receptors exclusively activated by designer drugs;
Keywords: G protein-coupled receptor; designer GPCR; DREADD; metabolism; diabetes; obesity
Mature Hippocampal Neurons Require LIS1 for Synaptic Integrity: Implications for Cognition
Keywords: Cognitive behavior; DREADD; LIS1; Plasticity; Synaptic excitation-inhibition; Synaptic homeostasis;
Gi protein functions in thalamic neurons to decrease orofacial nociceptive response
Keywords: VP; ventroposterior thalamic complex; Gi; inhibitory G protein; DREADD; designer receptor exclusively activated by a designer drug; LFP; Local field potentials; GIRK; Gi-coupled inwardly-rectifying potassium channels; VGLUT2; glutamate vesicular transport
Dopamine loss alters the hippocampus-nucleus accumbens synaptic transmission in the Tg2576 mouse model of Alzheimer's disease
Keywords: AAV; adeno-associated virus; aCSF; artificial cerebro-spinal fluid; AD; Alzheimer's disease; ANOVA; analysis of variance; AP; action potential; CaMKIIα; Ca2+/calmodulin-dependent protein kinase II alpha; Cm; cell capacitance; CNO; clozapine-N-oxide; DA;
Research articleInhibiting medial septal cholinergic neurons with DREADD alleviated anxiety-like behaviors in mice
Keywords: ChAT; choline acetyltransferase; CNO; clozapine N-oxide; DREADD; designer receptors exclusively activated by designer drugs; EPM; elevated plus-maze; MB; marble burying; MS; medial septum; NSF; novelty-suppressed feeding; OF; open field; PFA; paraformalde
Research PaperVentral medullary control of rapid eye movement sleep and atonia
Keywords: REM arousal; GABA; VGAT; DREADD; AAV;
Acute activation of GLP-1-expressing neurons promotes glucose homeostasis and insulin sensitivity
Keywords: Preproglucagon neurons; Glucagon-like peptides; Glucagon-Cre mice; Insulin sensitivity; Endogenous glucose production; Gluconeogenesis; aCSF; artificial cerebrospinal fluid; AP; area postrema; ARC; the arcuate nucleus; CC; central canal; ChAT; choline ace
Catecholaminergic A1/C1 neurons contribute to the maintenance of upper airway muscle tone but may not participate in NREM sleep-related depression of these muscles
Keywords: Obstructive sleep apnea; Sleep; hM4Di receptors; AAV; Genioglossus; DREADD; EEG;
Opioid-induced rewards, locomotion, and dopamine activation: A proposed model for control by mesopontine and rostromedial tegmental neurons
Keywords: μOR; mu opioid receptor; ACh; acetylcholine; AChR; acetylcholine receptor; ChAT; choline acetyltransferase; CPP; conditioned place preference; DA; dopamine; DREADD; designer receptors exclusively activated by designer drugs; GABA; gamma-aminobutyric acid
Effects of chemogenetic excitation or inhibition of the ventrolateral periaqueductal gray on the acquisition and extinction of Pavlovian fear conditioning
Keywords: Periaqueductal gray; DREADD; Extinction; Fear; Conditioning; Conditioned suppression;
The role of ghrelin-responsive mediobasal hypothalamic neurons in mediating feeding responses to fasting
Keywords: GHSR; Ghrelin receptors; Ghsr-IRES-Cre; DREADD; Food intake; Mediobasal hypothalamus;
Back to the Future: Circuit-testing TS & OCD
Keywords: ACH; acetylcholine; AMY; amygdala; cAMP; 3â²,5â²-cyclic adenosine monophosphate; CSTC; cortico/amygdalo-striato-thalamo-cortical; CT; cholera toxin; CTX; cortex; D1; dopamine receptor subtype 1; D1+; D1 receptor-expressing; D1CT-7; Dopamine receptor D1
Chemogenetic activation of dopamine neurons in the ventral tegmental area, but not substantia nigra, induces hyperactivity in rats
Keywords: Dopamine; DREADD; Chemogenetics; Ventral tegmental area; Substantia nigra; Locomotor activity;
DREADDs for Neuroscientists
Keywords: DREADD; chemogenetic; chemical biology; synthetic biology
Gq-DREADD Selectively Initiates Glial Glutamate Release and Inhibits Cue-induced Cocaine Seeking
Keywords: Astrocytes; Biosensor; Cocaine; DREADD; Glutamate; Reinstatement
New paradigms in GPCR drug discovery
Keywords: cAMP; 3â²,5â²-cyclic adenosine monophosphate; ADP; adenosine 5â²- diphosphate; GPCR; G protein-coupled receptor; TM; transmembrane helix; ERK; extracellular signal-regulated kinase; T4L; T-4 lysozyme; BRIL; thermostabilized apocytochrome b562; StaRs; s
Leptin receptor neurons in the dorsomedial hypothalamus are key regulators of energy expenditure and body weight, but not food intake
Keywords: Leptin; Thermoregulation; Energy expenditure; Dorsomedial hypothalamus; DREADD
Recent advances in optogenetics and pharmacogenetics
Keywords: Optogenetics; Pharmacogenetics; Channelrhodopsin; DREADD; Designer receptor; Viral transduction; Neurotransmitter signaling; Motivation/cognition; Autonomic function; Sensory function; Translational neuroscience
New tricks for old dogmas: Optogenetic and designer receptor insights for Parkinson's disease
Keywords: Optogenetic; DREADD; Parkinson's disease; Basal ganglia; Non-motor; Norepinephrine; Dopamine; Striatum
Pharmacosynthetics: Reimagining the pharmacogenetic approach
Keywords: Pharmacosynthetics; Pharmacogenetics; DREADD; RASSL; Synthetic biology