دانلود مقالات ISI درباره آسیب کبدی ناشی از مواد مخدر + ترجمه فارسی

Pathogenesis of Liver Injury in Acute Liver Failure

Keywords: آسیب کبدی ناشی از مواد مخدر; ALF; acute liver failure; ALFSG; US Acute Liver Failure Study Group; APAP; acetaminophen; DAMP; damage-associated molecular pattern; DILI; drug-induced liver injury; GWAS; genome-wide association study; HMGB-1; high-mobility group box-1; IL; interleukin;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Background incidence of liver chemistry abnormalities in pediatric clinical trials for conditions with and without underlying liver disease

Keywords: آسیب کبدی ناشی از مواد مخدر; ALT; alanine aminotransferase; TBIL; total bilirubin; ALP; alkaline phosphatase; LD; liver disease; HIV; human immunodeficiency virus; HBV; hepatitis B virus; ULN; upper limit of normal; CDC; Center for Disease Control and Prevention; Liver function tests

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticleHepatotoxicity associated with statins: Reports of idiosyncratic liver injury post-marketing

Keywords: آسیب کبدی ناشی از مواد مخدر; Hepatoxicity; Statins; Drug-induced liver injury;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Involvement of immune-related factors in diclofenac-induced acute liver injury in mice

Keywords: آسیب کبدی ناشی از مواد مخدر; Diclofenac; Drug-induced liver injury; Inflammation; IL-1β; IL-17

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Factores de riesgo y mecanismos de toxicidad hepática. Daño hepático inducido por medicamentos y tóxicos (excluido el alcohol)

Keywords: آسیب کبدی ناشی از مواد مخدر; Hepatotoxicidad; Daño hepático; Factores de riesgo; Causalidad; CronicidadHepatotoxicity; Drug-induced liver injury; Risk factors; Causality; Chronicity

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Case-crossover design: an alternative strategy for detecting drug-induced liver injury

Keywords: آسیب کبدی ناشی از مواد مخدر; Pharmacoepidemiology; Large databases; Case-control study; Case-crossover study; Poisoning; Drug-induced liver injury;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Mechanisms of the hepatoprotective effects of tamoxifen against drug-induced and chemical-induced acute liver injuries

Keywords: آسیب کبدی ناشی از مواد مخدر; Monocyte to macrophage differentiation-associated 2 (Mmd2); Estrogen receptor α; Species differences; Drug-induced liver injury; Chemical-induced liver injury

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

An overview of the preclinical toxicity and potential carcinogenicity of sitaxentan (Thelin®), a potent endothelin receptor antagonist developed for pulmonary arterial hypertension

Keywords: آسیب کبدی ناشی از مواد مخدر; ALP; alkaline phosphatase; ALT; alanaine aminotransferase; APTT; activated partial thromboplastin time; AST; aspartate aminotransferase; AUC; area under the curve; BID; twice daily; BSEP; bile salt export pump; CMC; carboxymethylcellulose; DILI; drug-indu

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticleMolecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity

Keywords: آسیب کبدی ناشی از مواد مخدر; ALF; acute liver failure; ALI; acute liver injury; ALT; alanine aminotransferase; APAP; acetaminophen; DILI; drug-induced liver injury; HMGB1; High Mobility Group Box-1 protein; KCC; Kings College Criteria; K18; keratin-18; LFT; liver function test; NAC;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Bile salt export pump inhibitors are associated with bile acid-dependent drug-induced toxicity in sandwich-cultured hepatocytes

Keywords: آسیب کبدی ناشی از مواد مخدر; 1-ABT; 1-aminobenzotriazole; BA; bile acid; BSEP/Bsep; human/rat bile salt export pump; CYP450; cytochrome P450; DILI; drug-induced liver injury; IC50; 50% inhibitory concentration; Ki; inhibition constant; LDH; lactate dehydrogenase; NAPQI; N-acetyl-p-be

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Drug-induced liver injury

Keywords: آسیب کبدی ناشی از مواد مخدر; cholestatic; direct toxic effect; drug-induced liver injury; drug metabolism; genetic susceptibility; hepatocellular; immunological

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Research ArticleAssociation of the hemochromatosis gene with pazopanib-induced transaminase elevation in renal cell carcinoma

Keywords: آسیب کبدی ناشی از مواد مخدر; VEGFR; vascular endothelial growth factor receptor; RCC; renal cell carcinoma; ALT; alanine aminotransferase; ULN; upper limit of the normal range; HLA; human leukocytic antigen; DILI; drug-induced liver injury; CC; case-control; QTA; quantitative trait

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Regulatory causality evaluation methods applied in kava hepatotoxicity: Are they appropriate?

Keywords: آسیب کبدی ناشی از مواد مخدر; Kava; Kava hepatotoxicity; Herbal hepatotoxicity; Drug-induced liver injury; Herbs induced liver injury; Hepatotoxicity; Toxic liver disease; Toxic liver injury; Causality assessment;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

IL-4 mediates dicloxacillin-induced liver injury in mice

Keywords: آسیب کبدی ناشی از مواد مخدر; 13,14-Dihydro-15-keto-prostaglandin D2; Drug-induced liver injury; IL-4

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Estradiol and progesterone modulate halothane-induced liver injury in mice

Keywords: آسیب کبدی ناشی از مواد مخدر; Drug-induced liver injury; Halothane; Estradiol; Progesterone

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

An Overview of Drug-induced Liver Injury

Keywords: آسیب کبدی ناشی از مواد مخدر; causality assessment method; cholestatic injury; direct hepatotoxicity; drug-induced liver injury; idiosyncratic immune reaction; hepatocellular injury; mixed injury

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Research ArticleNew insights on the mechanisms of valproate-induced hyperammonemia: Inhibition of hepatic N-acetylglutamate synthase activity by valproyl-CoA

Keywords: آسیب کبدی ناشی از مواد مخدر; Hyperammonemia; Urea cycle; Drug-induced liver injury; Drug-induced hepatotoxicity; N-acetylglutamate synthase; N-acetylglutamate; Valproate; Valproyl-CoA; VPA; valproic acid or 2-n-propylpentanoic acid; VP-CoA; valproyl-CoA; NAG; N-acetylglutamate; NAGS;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Current issues with acetaminophen hepatotoxicity—A clinically relevant model to test the efficacy of natural products

Keywords: آسیب کبدی ناشی از مواد مخدر; Drug-induced liver injury; Sterile inflammation; Oncotic necrosis and apoptosis; Oxidant stress and lipid peroxidation; Mitochondrial dysfunction

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Susceptibility to Amoxicillin-Clavulanate-Induced Liver Injury Is Influenced by Multiple HLA Class I and II Alleles

Keywords: آسیب کبدی ناشی از مواد مخدر; Hepatotoxicity; Genome-Wide Association Study; GWAS; Pharmacogenomics; AC; amoxicillin-clavulanate; AC-DILI; DILI following AC administration; ADME; drug absorption, distribution, metabolism, and excretion; ALP; alkaline phosphatase; ALT; alanine transami

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Toxic Hepatitis Induced by Gymnema sylvestre, a Natural Remedy for Type 2 Diabetes Mellitus

Keywords: آسیب کبدی ناشی از مواد مخدر; Drug-induced liver injury; Diabetes; Gymnema sylvestre; Natural remedy;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

The evaluation of drug rechallenge: The casopitant Phase III program

Keywords: آسیب کبدی ناشی از مواد مخدر; Rechallenge; Drug-induced liver injury; Hepatotoxicity; Mitochondrial dysfunction; Immunoallergic injury; Liver injury; Liver safety; Clinical trial; Casopitant

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Terbinafine stimulates the pro-inflammatory responses in human monocytic THP-1 cells through an ERK signaling pathway

Keywords: آسیب کبدی ناشی از مواد مخدر; Terbinafine; Butenafine; THP-1; Drug-induced liver injury

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Interleukin-17 is involved in α-naphthylisothiocyanate-induced liver injury in mice

Keywords: آسیب کبدی ناشی از مواد مخدر; Drug-induced liver injury; Cytokines; MIP-2; Neutrophils; Helper T cells

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Differential effect of covalent protein modification and glutathione depletion on the transcriptional response of Nrf2 and NF-κB

Keywords: آسیب کبدی ناشی از مواد مخدر; DILI; drug-induced liver injury; CRMs; chemically reactive metabolites; GSH; glutathione; Nrf2; nuclear factor-erythroid 2 (NF-E2)-related factor; NF-κB; NF-kappa B; ARE; anti-oxidant response element; NAPQI; N-acetyl-p-benzoquinineimine; DNCB; dinitroch

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Gastrointestinal and liver side effects of drugs in elderly patients

Keywords: آسیب کبدی ناشی از مواد مخدر; Amoxicillin/clavulanic acid; Drug-induced constipation; Drug-induced diarrhoea; Drug-induced gastrointestinal lesions; Drug-induced liver injury; Elderly; Hepatotoxicity; Isoniazid; Pill oesophagitis

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

The effect of active hexose correlated compound in modulating cytosine arabinoside-induced hair loss, and 6-mercaptopurine- and methotrexate-induced liver injury in rodents

Keywords: آسیب کبدی ناشی از مواد مخدر; Active hexose correlated compound (AHCC); 6-Mercaptopurine; Methotrexate; Cytosine arabinoside; Alopecia (hair loss); Drug-induced liver injury; Anticancer drugs; Cancer chemotherapy-side effects; Complementary medicine; Economics of cancer therapy

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

The long-term follow-up after idiosyncratic drug-induced liver injury with jaundice

Keywords: آسیب کبدی ناشی از مواد مخدر; DILI; drug-induced liver injury; HC; hepatocellular; CS; cholestatic; AIH; autoimmune hepatitis; SADRAC; Swedish Adverse Drug Reactions Advisory Committee; ULN; upper limit of normal; ADR; adverse drug reaction; Drug-induced liver injury; Adverse reaction

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Intravenous N-Acetylcysteine Improves Transplant-Free Survival in Early Stage Non-Acetaminophen Acute Liver Failure

Keywords: آسیب کبدی ناشی از مواد مخدر; CI; confidence interval; DILI; drug-induced liver injury; NAC; N-acetylcysteine;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Underlying mitochondrial dysfunction triggers flutamide-induced oxidative liver injury in a mouse model of idiosyncratic drug toxicity

Keywords: آسیب کبدی ناشی از مواد مخدر; ALT; alanine aminotransferase; BIC; bicalutamide; DILI; drug-induced liver injury; FLU; flutamide; OXPHOS; oxidative phosphorylation; ROS; reactive oxygen species; SOD2; superoxide dismutase-2 (Mn-SOD); TUNEL; terminal deoxynucleotidyl transferase-mediate

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Kava hepatotoxicity: Regulatory data selection and causality assessment

Keywords: آسیب کبدی ناشی از مواد مخدر; Drug-induced liver injury; Herbal hepatotoxicity; Kava hepatotoxicity; Liver disease

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Identification of structure-activity relationships for adverse effects of pharmaceuticals in humans: Part B. Use of (Q)SAR systems for early detection of drug-induced hepatobiliary and urinary tract toxicities

Keywords: آسیب کبدی ناشی از مواد مخدر; AERS; Computational toxicology; Drug adverse effects; Drug-induced liver injury; Drug-induced renal toxicity; In silico; Post-market reporting; Quantitative structure-activity relationships; QSAR software; SAR; SRS

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2009 سفارش ترجمه

EASL Clinical Practice Guidelines: Management of cholestatic liver diseases

Keywords: آسیب کبدی ناشی از مواد مخدر; Primary biliary cirrhosis; Primary sclerosing cholangitis; Overlap syndrome; Immunoglobulin G4-associated cholangitis; Drug-induced cholestatic liver disease; Genetic cholestatic liver disease; Cholestatic liver diseases in pregnancy; Intrahepatic cholest

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2009 سفارش ترجمه

Flucloxacillin-induced liver injury

Keywords: آسیب کبدی ناشی از مواد مخدر; Flucloxacillin; Drug-induced liver injury; Cytochrome P450

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Troglitazone-induced hepatic mitochondrial proteome expression dynamics in heterozygous Sod2+/− mice: Two-stage oxidative injury

Keywords: آسیب کبدی ناشی از مواد مخدر; ACO2, aconitase-2 (mitochondrial form); 2D-DIGE, two-dimensional difference gel electrophoresis; DILI, drug-induced liver injury; ETC, electron transport chain; SOD, superoxide dismutase.Troglitazone; Idiosyncratic drug toxicity; Drug-induced liver injury

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Are HIV-infected patients candidates for liver transplantation?

Keywords: آسیب کبدی ناشی از مواد مخدر; DILI; drug-induced liver injury; AUC; area under the curve; HBV; hepatitis B Virus; HCV; hepatitis C virus; HIV; human immunodeficiency virus; AIDS; acquired immunodeficiency syndrome; MELD; model for end-stage liver disease; CPT; child-pugh-turcott;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Causes, Clinical Features, and Outcomes From a Prospective Study of Drug-Induced Liver Injury in the United States

Keywords: آسیب کبدی ناشی از مواد مخدر; DILI; drug-induced liver injury; DILIN; Drug-Induced Liver Injury Network; INR; international normalized ratio; RUCAM; Roussel Uclaf Causality Assessment Method; ULN; upper limit of normal;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2008 سفارش ترجمه

Serum Apoptosis Markers in Acute Liver Failure: A Pilot Study

Keywords: آسیب کبدی ناشی از مواد مخدر; ALF; acute liver failure; ALFSG; Acute Liver Failure Study Group; DILI; drug-induced liver injury; ELISA; enzyme-linked immunosorbent assay; HGF; hepatocyte growth factor; IFN; interferon; IL-6; interleukin-6; INR; international normalized ratio; sFas; so

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Genetic polymorphisms of manganese superoxide dismutase, NAD(P)H:quinone oxidoreductase, glutathione S-transferase M1 and T1, and the susceptibility to drug-induced liver injury

Keywords: آسیب کبدی ناشی از مواد مخدر; Manganese superoxide dismutase; NAD(P)H:quinone oxidoreductase; Glutathione S-transferase; Drug-induced liver injury; Toxic hepatitis; Drug metabolizing enzyme; Genetic polymorphism

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Mitochondrial abnormalities-A link to idiosyncratic drug hepatotoxicity?

Keywords: آسیب کبدی ناشی از مواد مخدر; Mitochondria; Drug-induced liver injury; Susceptibility factors; Drug idiosyncrasy; Oxidative stress;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2007 سفارش ترجمه

Clinical characteristics and prognostic markers in disulfiram-induced liver injury

Keywords: آسیب کبدی ناشی از مواد مخدر; Drug-induced liver injury; Disulfiram: hepatotoxicity; Liver transplantation; MortalityHC, hepatocellular; DILD, drug-induced liver disease; SADRAC, Swedish Adverse Drug Reactions Advisory Committee; ULN, upper limit of normal; IQR, interquartile range; A

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Genetics of Hepatobiliary Diseases

Keywords: آسیب کبدی ناشی از مواد مخدر; α1-AT; alpha 1 anti-trypsin; ADH; alcohol dehydrogenase; ADPKD; autosomal dominant polycystic kidney disease; ADPLD; autosomal dominant polycystic liver disease; ALD; alcoholic liver disease; AOR; adjusted odds ratio; CI; confidence interval; CTLA-4; cyt

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Drug-Induced Liver Injury: An Analysis of 461 Incidences Submitted to the Spanish Registry Over a 10-Year Period

Keywords: آسیب کبدی ناشی از مواد مخدر; DILI; drug-induced liver injury; FHF; fulminant hepatic failure;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه