دانلود مقالات ISI درباره آسیب کبدی ناشی از مواد مخدر + ترجمه فارسی

Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study

Keywords: آسیب کبدی ناشی از مواد مخدر; Medication; Liver Damage; Side Effect; Anti-Fungal Agent; AF; allele frequency; CM; cholestatic-mixed; DILI; drug-induced liver injury; DILIN; Drug-Induced Liver Injury Network; GWAS; genome-wide association study; HC; hepatocellular; iDILIC; Internationa

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Safety assessment of the dietary supplement OxyELITE™ Pro (New Formula) in inbred and outbred mouse strains

Keywords: آسیب کبدی ناشی از مواد مخدر; Dietary supplements; Drug-induced liver injury; Hepatotoxicity; Phytochemicals; ALT; alanine aminotransferase; APAP; acetaminophen; AST; aspartate aminotransferase; DILI; drug-induced liver injury; DILIN; Drug-Induced Liver Injury Network; DMAA; 1,3-dimet

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

CORAL: Binary classifications (active/inactive) for drug-induced liver injury

Keywords: آسیب کبدی ناشی از مواد مخدر; QSAR; Drug-induced liver injury; Monte Carlo method; Predictive toxicology; Risk assessment;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2017 سفارش ترجمه

Metabolically active extracellular vesicles released from hepatocytes under drug-induced liver-damaging conditions modify serum metabolome and might affect different pathophysiological processes

Keywords: آسیب کبدی ناشی از مواد مخدر; Extracellular vesicles; Metabolomics; Drug-induced liver injury; Serum; Diclofenac; Acetaminophen; Exosomes;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

3D in vitro models of liver fibrosis

Keywords: آسیب کبدی ناشی از مواد مخدر; HSCs; hepatic stellate cells; ALT; alanine aminotransferase; APAP; acetaminophen; AST; aminotransferase; CBDL; common biled duct ligation; DAMPs; damage associated molecular patterns; DCM; decellularized matrix; DILI; drug-induced liver injury; ECM; extra

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Identification of Bile Acids Responsible for Inhibiting the Bile Salt Export Pump, Leading to Bile Acid Accumulation and Cell Toxicity in Rat Hepatocytes

Keywords: آسیب کبدی ناشی از مواد مخدر; biliary excretion; in vitro models; toxicology; bile acid transporters; efflux pumps; BA; bile acid; BSEP; bile salt export pump; CA; cholic acid; CDCA; chenodeoxycholic acid; CsA; cyclosporin A; DCA; deoxycholic acid; DILI; drug-induced liver injury; DM

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

Rifampicin-induced injury in HepG2 cells is alleviated by TUDCA via increasing bile acid transporters expression and enhancing the Nrf2-mediated adaptive response

Keywords: آسیب کبدی ناشی از مواد مخدر; RFP; rifampicin; TUDCA; tauroursodeoxycholic acid; Nrf2; nuclear factor erythroid 2-related factor; DILI; drug-induced liver injury; ALF; acute liver failure; TB; tuberculosis; INH; isoniazid; GSH; glutathione; BAs; bile acids; ER; endoplasmic reticulum;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Sertraline-Associated Cholestasis and Ductopenia Consistent with Vanishing Bile Duct Syndrome

Keywords: آسیب کبدی ناشی از مواد مخدر; DILI; Drug-induced liver injury; SSRI; Selective serotonin reuptake inhibitor; VBDS; Vanishing bile duct syndrome;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Acute Hepatitis in the DRESS Syndrome

Keywords: آسیب کبدی ناشی از مواد مخدر; Drug Hypersensitivity Syndrome; Drug-Induced Liver Injury; Liver Failure, Acute/chemically induced; Sulfasalazine/adverse effects; Doença Hepática Induzida por Medicamentos; Falência Hepática Aguda/induzida quimicamente; Síndrome de Hipersensibilidad

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Chronic hepatitis B infection and risk of antituberculosis drug-induced liver injury: Systematic review and meta-analysis

Keywords: آسیب کبدی ناشی از مواد مخدر; drug-induced liver injury; hepatitis B; meta-analysis; tuberculosis

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Assessment of mitochondrial dysfunction-related, drug-induced hepatotoxicity in primary rat hepatocytes

Keywords: آسیب کبدی ناشی از مواد مخدر; Primary rat hepatocytes; Mitochondrial toxicity; Oxygen requirement; Galactose; Transferrin; Drug-induced liver injury

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

High content analysis assay for prediction of human hepatotoxicity in HepaRG and HepG2 cells

Keywords: آسیب کبدی ناشی از مواد مخدر; DILI; drug-induced liver injury; GLP; good laboratory practice; HCA; high content analysis; ROS; reactive oxygen species; GSH; glutathione; MMP; mitochondrial membrane potential; MP; membrane permeability; CM-H2DCFDA; 5-(and-6)-chloromethyl-2′,7′-dich

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Exosomes in liver pathology

Keywords: آسیب کبدی ناشی از مواد مخدر; CCA; cholangiocarcinoma; DILI; drug-induced liver injury; EV; extracellular vesicle; MVBs; multivesicular bodies; HBV; hepatitis B virus; HCC; hepatocellular carcinoma; HCV; hepatitis C virus; IFN; interferon; LPS; lipopolysaccharide; miRNA; microRNA; MSC

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibition of bile salt transport by drugs associated with liver injury in primary hepatocytes from human, monkey, dog, rat, and mouse

Keywords: آسیب کبدی ناشی از مواد مخدر; Bile salt export pump; BSEP; ABCB11; Drug-induced liver injury; DILI; Bile salts; Hepatocytes; Species differenceBSEP, bile salt export pump; CA, cholic acid; CDCA, chenodeoxycholic acid; DILI, drug-induced liver injury; GCA, glycocholic acid; GCDCA, glyc

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Caffeic acid attenuated acetaminophen-induced hepatotoxicity by inhibiting ERK1/2-mediated early growth response-1 transcriptional activation

Keywords: آسیب کبدی ناشی از مواد مخدر; Caffeic acid; Acetaminophen; Hepatotoxicity; Detoxification; Egr1; ERK1/2; ALT/AST; alanine/aspartate aminotransferase; CA; caffeic acid; CYP450; cytochrome P450; DILI; Drug-induced liver injury; Egr1; early growth response1; ELISA; Enzyme-linked immunoso

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Establishment of a Drug-Induced, Bile Acid-Dependent Hepatotoxicity Model Using HepaRG Cells

Keywords: آسیب کبدی ناشی از مواد مخدر; hepatocytes; bile acid transporters; biliary excretion; in vitro models; toxicology; cell lines; ALP; alkaline phosphatase; BA; bile acid; BEI; biliary excretion index; BSEP/Bsep; bile salt export pump; CsA; cyclosporine A; DILI; drug-induced liver injur

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Pathogenetic analyses of carbamazepine-induced liver injury in F344 rats focused on immune- and inflammation-related factors

Keywords: آسیب کبدی ناشی از مواد مخدر; ALT; alanine aminotransferase; APAP; acetaminophen; ATP; adenosine triphosphate; BSO; l-buthionine S,R-sulfoximine; CBZ; carbamazepine; CD; cluster of differentiation; CV; centrilobular vein; CYP; cytochrome P450; DAMPs; damage-associated molecular patter

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Drug-induced cholestasis risk assessment in sandwich-cultured human hepatocytes

Keywords: آسیب کبدی ناشی از مواد مخدر; BAs; bile acids; Cmax; maximum plasma concentration; CDF(DA); 5-(6)-carboxy-2′,7′-dichlorofluorescein (diacetate); DIC(I); drug-induced cholestasis (index); DILI; drug-induced liver injury; IMI; Innovative Medicine Initiative; MIP-DILI; Mechanism-Base

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2016 سفارش ترجمه

MDCT dynamic enhancement appearances in acute liver failure

Keywords: آسیب کبدی ناشی از مواد مخدر; Acute liver failure; Drug-induced liver injury; Multidetector CT; Necrosis of hepatocytes; Nodular regeneration

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2015 سفارش ترجمه

Drug biokinetic and toxicity assessments in rat and human primary hepatocytes and HepaRG cells within the EU-funded Predict-IV project

Keywords: آسیب کبدی ناشی از مواد مخدر; AMI; amiodarone; ADR; adverse drug reaction; CPZ; chlorpromazine; CsA; cyclosporine A; CYP; cytochrome P450-dependent monooxygenases; DICI; Drug Induced Cholestasis Index; DILI; drug-induced liver injury; DME; drug metabolizing enzyme; IBU; ibuprofen; NSA

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

The utility of HepG2 cells to identify direct mitochondrial dysfunction in the absence of cell death

Keywords: آسیب کبدی ناشی از مواد مخدر; ADR; adverse drug reaction; CCCP; carbonyl cyanide m-chlorophenyl hydrazine; DILI; drug-induced liver injury; ETC; electron transport chain; EC50-ATP; drug concentration which decreases cellular ATP level by 50%; EC150-CT; drug concentration which increas

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Multiparametric assay using HepaRG cells for predicting drug-induced liver injury

Keywords: آسیب کبدی ناشی از مواد مخدر; HepaRG cells; Multiparametric assay; Drug-induced liver injury

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Hepatitis E Virus Infection as a Possible Cause of Acute Liver Failure in Europe

Keywords: آسیب کبدی ناشی از مواد مخدر; Liver Disease; Hepatitis E; Blood Test; Diagnosis; ALF; acute liver failure; ALT; alanine aminotransferase; AST; aspartate aminotransferase; DILI; drug-induced liver injury; ELT; emergency liver transplantation; GVHD; graft-versus-host disease; HEV; hepat

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Comedications alter drug-induced liver injury reporting frequency: Data mining in the WHO VigiBase™

Keywords: آسیب کبدی ناشی از مواد مخدر; ACEI; angiotensin converting enzyme inhibitor; ADE; adverse drug events; AERS; adverse event reporting system; APAP; acetaminophen; ATC classification; Anatomical Therapeutic Chemical Classification; ATIIA; angiotensin II receptor antagonist; BSEP; bile s

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

GastrointestinalRegorafenib suppresses sinusoidal obstruction syndrome in rats

Keywords: آسیب کبدی ناشی از مواد مخدر; Colorectal liver metastasis; Kinase inhibitor; Drug-induced liver injury; Metalloproteinase-9; Extracellular signal-regulated kinase;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Herbal Products and the Liver: A Review of Adverse Effects and Mechanisms

Keywords: آسیب کبدی ناشی از مواد مخدر; Dietary Supplement Health and Education Act; Contamination and Adulteration; Herbal Therapie; sSilymarin; ALT; alanine aminotransferase; CAM; complementary and alternative medicine; CHC; chronic hepatitis C; CYP; cytochrome P450; DILI; drug-induced liver

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2015 سفارش ترجمه

Quinolones-induced hypersensitivity reactions

Keywords: آسیب کبدی ناشی از مواد مخدر; ADR; adverse drug reaction; ALT; alanine aminotransferase; AST; aspartate aminotransferase; CI; confidence interval; DILI; drug-induced liver injury; FDE; fixed drug eruption; HSR; hypersensitivity syndrome reaction; γGT; gamma gluthamyl transferase; IDH

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2015 سفارش ترجمه

EASL Clinical Practice Guidelines: Autoimmune hepatitis

Keywords: آسیب کبدی ناشی از مواد مخدر; ACG; American College of Gastroenterology; AGA; American Gastroenterological Association; ANCA; Antineutrophil cytoplasmic antibodies; APECED; Autoimmune polyendocrinopathy-cadidiasis ectodermal dystrophy; AS; acute severe autoimmune; CNI; Calcineurin inh

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2015 سفارش ترجمه

Zebrafish: An Important Tool for Liver Disease Research

Keywords: آسیب کبدی ناشی از مواد مخدر; Development; Technology; Liver Cancer; Toxicology; Regeneration; ALD; alcoholic liver disease; CYP; cytochrome P450; DILI; drug-induced liver injury; DMBA; dimethylbenzanthracene; dpf; days postfertilization; ER; endoplasmic reticulum; FLD; fatty liver di

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2015 سفارش ترجمه

Research ArticleRivaroxaban postmarketing risk of liver injury

Keywords: آسیب کبدی ناشی از مواد مخدر; Rivaroxaban; Drug-induced liver injury; Hepatotoxicity; Adverse drug reactions; Postmarketing; Pharmacovigilance; Anticoagulants; Factor Xa inhibitors; Drug safety;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

The role of intrahepatic CD3 +/CD4 −/CD8 − double negative T (DN T) cells in enhanced acetaminophen toxicity

Keywords: آسیب کبدی ناشی از مواد مخدر; GrB; granzyme B; DN T; double negative T; APAP; acetaminophen; DILI; drug-induced liver injury; NAPQI; n-acetyl-benzoquinone imine; NK; natural killer; CTL; cytotoxic T lymphocytes; FasL; Fas ligand; Gr; granzyme; i.p; intraperitoneally; ALT; alanine tran

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Mechanisms of acetaminophen-induced cell death in primary human hepatocytes

Keywords: آسیب کبدی ناشی از مواد مخدر; Drug-induced liver injury; Acetaminophen protein adducts; Oncotic necrosis; c-Jun-N-terminal kinase; Mitochondrial dysfunction

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Involvement of miRNAs in the early phase of halothane-induced liver injury

Keywords: آسیب کبدی ناشی از مواد مخدر; ACTB; β-actin; ALT; alanine aminotransferase; APAP; acetaminophen; CXCL1; chemokine (C-X-C motif) ligand 1; CYP; cytochrome P450; DILI; drug-induced liver injury; GAPDH; glyceraldehyde-3-phoshate dehydrogenase; Ct; cycle threshold; HAL; halothane; IL; in

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

The Impact of Obesity and Metabolic Syndrome on Chronic Hepatitis B and Drug-Induced Liver Disease

Keywords: آسیب کبدی ناشی از مواد مخدر; Fatty liver; Steatosis; Metabolic syndrome; Chronic hepatitis B; Drug-induced liver injury; Fibrosis; Cirrhosis; Hepatocellular carcinoma;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Use of Hy's Law and a New Composite Algorithm to Predict Acute Liver Failure in Patients With Drug-Induced Liver Injury

Keywords: آسیب کبدی ناشی از مواد مخدر; Idiosyncratic Hepatotoxicity; Prognostic Risk Factor; Prediction; Progression; ALF; acute liver failure; ALP; alkaline phosphatase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; AUROC; area under receiver operating characteristic curve;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

Case ReportSevere immune-mediated drug-induced liver injury linked to ibandronate: A case report

Keywords: آسیب کبدی ناشی از مواد مخدر; AST; aspartate aminotransferase; ALT; alanine aminotransferase; CT; computed tomography; HIV; human immunodeficiency virus; N; normal; DILI; drug-induced liver injury; AIH; auto-immune hepatitis; ULN; upper limit of normal; RUCAM; Roussel Uclaf Causality

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Isoniazid-induced cell death is precipitated by underlying mitochondrial complex I dysfunction in mouse hepatocytes

Keywords: آسیب کبدی ناشی از مواد مخدر; ALT; Alanine aminotransferase; AST; Aspartate aminotransferase; BNPP; Bis-p-nitrophenyl phosphate; DILI; Drug-induced liver injury; ETC; Electron transport chain; HzN; Hydrazine; INH; Isoniazid (isonicotinic acid hydrazide); LDH; Lactate dehydrogenase; OC

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Insuffisances hépatiques aiguës sévères d’origine toxique : prise en charge étiologique et symptomatique

Keywords: آسیب کبدی ناشی از مواد مخدر; Hépatite toxique; Hépatite médicamenteuse; Insuffisance hépatique aiguëToxic hepatitis; Drug-induced liver injury; Acute liver failure

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Clinical Manifestations and Treatment of Drug-induced Hepatotoxicity

Keywords: آسیب کبدی ناشی از مواد مخدر; Drug-induced liver injury; Drug-induced cholestasis; Drug-induced hepatocellular injury; Management of drug-induced liver injury;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Liver Injury From Tumor Necrosis Factor-α Antagonists: Analysis of Thirty-four Cases

Keywords: آسیب کبدی ناشی از مواد مخدر; Drug-Induced Liver Injury; Tumor Necrosis Factor; TNF-α Antagonists; Hepatotoxicity; Autoimmunity; AIH; autoimmune hepatitis; Alk Phos; alkaline phosphatase; ALT; alanine aminotransferase; ANA; antinuclear antibody; ASMA; anti-smooth muscle antibody; A

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Human induced pluripotent stem cells and their use in drug discovery for toxicity testing

Keywords: آسیب کبدی ناشی از مواد مخدر; Induced pluripotent stem cells; Drug-induced liver injury; Cardiomyocytes; Microelectrode array; Toxicity

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Drug-Induced Liver Injury from Antiepileptic Drugs

Keywords: آسیب کبدی ناشی از مواد مخدر; Antiepileptic drugs; Drug-induced liver injury; Hepatotoxicity;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Hepatotoxicity Related to Anti-tuberculosis Drugs: Mechanisms and Management

Keywords: آسیب کبدی ناشی از مواد مخدر; drug-induced liver injury; hepatotoxicity; tuberculosis; genetic; pathogenesisTB, tuberculosis; WHO, World Health Organization; DILI, drug-induced liver injury; ALT, alanine transaminase; AST, aspartate transaminase; ULN, upper limit of normal range; FDA,

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Antiretroviral and Anti-Hepatitis C Virus Direct-Acting Antiviral-Related Hepatotoxicity

Keywords: آسیب کبدی ناشی از مواد مخدر; HIV; HCV; Coinfection; ARV; DAAs; Hepatotoxicity; Drug-induced liver injury;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Nonsteroidal Anti-Inflammatory Drug-Induced Hepatoxicity

Keywords: آسیب کبدی ناشی از مواد مخدر; Nonsteroidal anti-inflammatory drugs; Drug-induced liver injury; Acute liver injury; Liver transplantation; Idiosyncratic hepatotoxicity; Hy's law; Drug safety; Drug surveillance;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Lipid-Lowering Agents and Hepatotoxicity

Keywords: آسیب کبدی ناشی از مواد مخدر; Lipid-lowering agents; Hepatotoxicity; Statins; Drug-induced liver injury;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

How to Avoid Being Surprised by Hepatotoxicity at the Final Stages of Drug Development and Approval

Keywords: آسیب کبدی ناشی از مواد مخدر; Drug-induced liver injury; Hy's Law; Causality assessment; Drug development;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2013 سفارش ترجمه

Acetaminophen-related Hepatotoxicity

Keywords: آسیب کبدی ناشی از مواد مخدر; Acetaminophen; Hepatotoxicity; Overdose; Drug-induced liver injury; Acute liver failure; N-acetylcysteine; Liver transplantation;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2013 سفارش ترجمه

Hepatotoxicity of Antibiotics

Keywords: آسیب کبدی ناشی از مواد مخدر; Drug-induced liver injury; Antibiotics; Drug safety; Monitoring;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2013 سفارش ترجمه

A prospective study on the safety of herbal medicines, used alone or with conventional medicines

Keywords: آسیب کبدی ناشی از مواد مخدر; Safety; Drug-induced liver injury; Adverse drug reaction; Herbal medicine;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه