دانلود مقالات ISI درباره DSB، شکست دو رشته + ترجمه فارسی

نقش اکسید نیتریک در اثر تابش ناشی از تابش

Role of nitric oxide in the radiation-induced bystander effect

Keywords: DSB، شکست دو رشته; BRCA1, breast cancer type 1 susceptibility protein; Cav-1, caveolin 1 protein; cGy, centigray; cNOS, constitutive nitric oxide synthase; c-PTIO, 2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide; DSB, double-strand break; E2F4, transcripti

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

تقویت هم افزایی از سمیت سلولی (-) - lomaiviticin توسط مهارکننده ATR VE-821

Synergistic potentiation of (−)-lomaiviticin A cytotoxicity by the ATR inhibitor VE-821

Keywords: DSB، شکست دو رشته; ATR, ataxia telangiectasia and Rad3-related protein; SSB, single-strand break; DSB, double-strand break; PI3KK, phosphatidylinositol 3-kinase-related kinase; ATM, ataxia telangiectasia mutated; DNA-PKcs, DNA-dependent protein kinase catalytic subunit; BRC

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

T0070907 باعث مهار ترمیم آسیب DNA ناشی از تشعشع با هدف قرار دادن RAD51 می شود

T0070907 inhibits repair of radiation-induced DNA damage by targeting RAD51

Keywords: DSB، شکست دو رشته; DNA-PK, DNA-dependent protein kinase; DNA-PKcs, DNA-dependent protein kinase catalytic subunit; DSB, double-strand break; FBS, foetal bovine serum; HR, homologous recombination; IR, ionising radiation; NHEJ, non-homologous end joining; PPARγ, peroxisome p

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

SNF2H interacts with XRCC1 and is involved in repair of H2O2-induced DNA damage

Keywords: DSB، شکست دو رشته; AP sites, apurinic/apyrimidinic sites; BER, base excision repair; CBB, Coomassie Brilliant Blue; CK2, , casein kinase 2; DSB, double-strand break; OGG1, 8-oxoguanine DNA glycosylase; PAR, poly(ADP-ribose); PARP, poly(ADP-ribose) polymerase; SNF2H, sucrose

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Ku antigen displays the AP lyase activity on a certain type of duplex DNA

Keywords: DSB، شکست دو رشته; AP site, apurinic/apyrimidinic site; APE1, apurinic/apyrimidinic endonuclease 1; BER, base excision repair; dRP, deoxyribose phosphate; DSB, double-strand break; Endo III, Escherichia coli endonuclease III; GAPDH, glyceraldehyde-3-phosphate dehydrogenase;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

A Selective Small Molecule DNA2 Inhibitor for Sensitization of Human Cancer Cells to Chemotherapy

Keywords: DSB، شکست دو رشته; BLM, Bloom Syndrome; CPT, camptothecin; DNA2, DNA2 nuclease/helicase; DSB, double-strand break; EMSA, electrophoretic mobility shift assay; EXO1, exonuclesae 1; FA, Fanconi anemia; FEN1, flap endonuclease 1; HDR, homology direct repair; HTS, high throughp

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Zinc finger nuclease technology: Advances and obstacles in modelling and treating genetic disorders

Keywords: DSB، شکست دو رشته; ZFN, Zinc finger nuclease; DSB, double-strand break; TFIII, transcription factor III; NHEJ, non-homologous end joining; TF, transcription factor; HDR, homology directed repair; HR, homologous recombination; XSCID, human X-linked sever combined immunodefic

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Yet another job for Dna2: Checkpoint activation

Keywords: DSB، شکست دو رشته; 9–1–1, human Rad9, Rad1, Hus1 (yeast Ddc1, Rad17, Mec3) checkpoint clamp; ATM, ataxia-telangiectasia mutated; ATR, ATM and Rad3–related; ATRIP, ATR interacting protein; DSB, double-strand break; dsDNA, double-stranded DNA; ssDNA, single-stranded DNA; FEN1

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Chromatin dynamics after DNA damage: The legacy of the access–repair–restore model

Keywords: DSB، شکست دو رشته; ARR, access–repair–restore; ASF1, anti-silencing function 1; BRG1, Brahma-related gene 1; CAF-1, chromatin assembly factor-1; CENPA, centromeric protein A; DAXX, death domain-associated protein; DDB2, DNA damage binding protein 2; DSB, double-strand break

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Biochemical mechanism of DSB end resection and its regulation

Keywords: DSB، شکست دو رشته; DSB, double-strand break; HR, homologous recombination; NHEJ, nonhomologous end joining; MMEJ, microhomolgy-mediated end joining; MRN, MRE11–RAD50–NBS1 complex; RPA, replication protein AResection; Recombination; Double-strand breaks; Nucleases; Helicases

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Sensitization of Pancreatic Cancers to Gemcitabine Chemoradiation by WEE1 Kinase Inhibition Depends on Homologous Recombination Repair 12

Keywords: DSB، شکست دو رشته; DSB, double-strand break; HR, homologous recombination; RER, radiation enhancement ratio; RT, radiation

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Multifaceted control of DNA repair pathways by the hypoxic tumor microenvironment

Keywords: DSB، شکست دو رشته; ATM, ataxia telangiectasia mutated; ATR, ataxia telangiectasia and Rad3-related; BER, base excision repair; DSB, double-strand break; H3K4me2, histone H3 lysine 4 dimethylation; H3K4me3, histone H3 lysine 4 trimethylation; H3K9me2, histone H3 lysine 9 dim

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

A complex microcephaly syndrome in a Pakistani family associated with a novel missense mutation in RBBP8 and a heterozygous deletion in NRXN1

Keywords: DSB، شکست دو رشته; ATR, ataxia–telangiectasia and RAD3-related; BMI, Body mass index; CBC, complete blood count; CNV, copy number variation; DDR, DNA-damage response; DSB, Double-strand break; EGF, epidermal growth factor; ID, intellectual disability; Mb, megabase; MIM, Men

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

TALEN construction via “Unit Assembly” method and targeted genome modifications in zebrafish

Keywords: DSB، شکست دو رشته; Cas, CRISPR-associated; CRISPR, clustered regularly-interspaced short palindromic repeats; dpf, days post-fertilization; DSB, double-strand break; HR, homologous recombination; NHEJ, non-homologous end-joining; TALE, transcription activator-like effector;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

p53-Dependent suppression of genome instability in germ cells

Keywords: DSB، شکست دو رشته; Medaka fish; Microsatellite instability; Radiation; Spermatogonial stem cell; msh2; p53CE, fluorescent capillary electrophoresis; DDR, DNA damage response; DSB, double-strand break; ESTR, expanded simple tandem repeat; HRM, high-resolution melting; MMR, m

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Endonucleases: new tools to edit the mouse genome

Keywords: DSB، شکست دو رشته; CRISPR/Cas, clustered regularly interspaced short palindromic repeats/CRISPR-associated; crRNA, CRISPR RNA; DSB, double-strand break; dsDNA, double-strand DNA; ES, embryonic stem; FLASH, fast ligation-based automatable solid-phase high-throughput; gRNA, g

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

A Preclinical Study Combining the DNA Repair Inhibitor Dbait with Radiotherapy for the Treatment of Melanoma 1

Keywords: DSB، شکست دو رشته; DNA-PK, DNA-dependent kinase; DSB, double-strand break; PARP, poly-adenyl-ribose polymerase; RT, radiation therapy; SSB, single-strand break; TGD, tumor growth delay

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

PARP-mediated repair, homologous recombination, and back-up non-homologous end joining-like repair of single-strand nicks

Keywords: DSB، شکست دو رشته; DSB, double-strand break; HR, homologous recombination; NHEJ, non-homologous end-joining; TLR, Traffic Light ReporterHomologous recombination; Non-homologous end-joining; PARP; Single-strand nick; Nickase; Gene correction

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

A recombinase paralog from the hyperthermophilic crenarchaeon Sulfolobus solfataricus enhances SsoRadA ssDNA binding and strand displacement

Keywords: DSB، شکست دو رشته; dsDNA, double-strand DNA; ssDNA, single-strand DNA; Gy, Gray; IR, ionizing radiation; UV, ultraviolet; DSB, double-strand break; HR, homologous recombination; bp, basepairs; EMSA, electrophoretic mobility shift assay; ORF, open reading frameArchaea; Recom

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Recombinase-mediated cassette exchange (RMCE) — A rapidly-expanding toolbox for targeted genomic modifications

Keywords: DSB، شکست دو رشته; attB/attP, recombinase-attachment sites within the bacterial and phage genomes; ccc, covalently-closed circular; Cre, cyclization recombinase/causes recombination; DSB, double-strand break; ESC, embryonic stem cell; flexing, Flp-mediated excision; EUCOMM,

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2013 سفارش ترجمه

SIRT1 as a therapeutic target in inflammaging of the pulmonary disease

Keywords: DSB، شکست دو رشته; AICAR, 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside; AMPK, AMP-activated kinase; ATM, ataxia telangiectasia mutated; CHK2, checkpoint kinase 2; COPD, chronic obstructive pulmonary disease; DDR, DNA damage response; DSB, double-strand break; EGCG, e

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Fully functional global genome repair of (6-4) photoproducts and compromised transcription-coupled repair of cyclobutane pyrimidine dimers in condensed mitotic chromatin

Keywords: DSB، شکست دو رشته; CPD, cyclobutane pyrimidine dimer; DHFR, dihydrofolate reductase; DSB, double-strand break; ELISA, enzyme-linked immunosorbent assay; HR, homologous recombination; NHEJ, nonhomologous end joining; 6-4PP, (6-4) pyrimidine–pyrimidone photoproduct; T4 endo V

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

“Delayed death” phenomenon: A synergistic action of cyclophosphamide and exogenous DNA

Keywords: DSB، شکست دو رشته; CP, cyclophosphamide; ICL, interstrand cross-link; HSC, hematopoietic stem cell; DSB, double-strand break; BMC, bone marrow cellBone marrow cells; Systemic inflammation; Involution of lymphoid organs; Mouse short interspersed elements; Apoptosis

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

ATR–Chk1 signaling pathway and homologous recombinational repair protect cells from 5-fluorouracil cytotoxicity

Keywords: DSB، شکست دو رشته; 5-FU, 5-fluorouracil; FUTP, fluorouridine triphosphate; FdUTP, fluorodeoxyuridine triphosphate; FdUMP, fluorodeoxyuridine monophosphate; TS, thymidylate synthase; BER, base excision repair; MMR, mismatch repair; DSB, double-strand break; HRR, homologous r

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Involvement of MRE11A and XPA gene polymorphisms in the modulation of DNA double-strand break repair activity: A genotype–phenotype correlation study

Keywords: DSB، شکست دو رشته; SNP, single nucleotide polymorphism; PBMC, peripheral blood mononuclear cells; DSB, double-strand break; DSBR, double-strand break repair; IR, ionizing radiation; NER, nucleotide excision repair; LD, linkage disequilibrium; MRN complex, MRE11–RAD50–NBS1 c

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Sequences in PSF/SFPQ mediate radioresistance and recruitment of PSF/SFPQ-containing complexes to DNA damage sites in human cells

Keywords: DSB، شکست دو رشته; RRM, RNA recognition motif; PSF, polypyrimidine tract binding protein-associated splicing factor; DSB, double-strand break; DBHS, Drosophila behavior human splicingPSF; Radiation sensitivity; Double-strand break repair; Laser-induced DNA damage

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Detection of DNA damage in oocytes of small ovarian follicles following phosphoramide mustard exposures of cultured rodent ovaries in vitro

Keywords: DSB، شکست دو رشته; Ab, antibody; ATM, ataxia-telangiectasia mutated; ATR, ATM-related; CPA, cyclophosphamide; DMSO, dimethyl sulfoxide; DNA-PK, DNA-dependent protein kinases; DSB, double-strand break; IHC, immunohistochemistry; IR, ionizing radiation; PIKK, phosphatidylinos

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

The DNA damage checkpoint allows recombination between divergent DNA sequences in budding yeast

Keywords: DSB، شکست دو رشته; DDR, DNA damage response; SSA, single-strand annealing; DSB, double-strand break; BIR, break-induced replication; HR, homologous recombination; ssDNA, single-stranded DNA; NHEJ, non-homologous end joining; SDSA, synthesis-dependent strand annealing; TLS,

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Physiological consequences of defects in ERCC1–XPF DNA repair endonuclease

Keywords: DSB، شکست دو رشته; CS, Cockayne syndrome; COFS, cerebro-oculo-facio-skeletal syndrome; CPD, cyclopyrimidine dimer; CSR, class switch recombination; DSB, double-strand break; ERCC1, excision repair cross complementation group 1; HR, homologous recombination; ICL, interstrand

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Repair of DNA Double-Strand Breaks Induced by Ionizing Radiation Damage Correlates with Upregulation of Homologous Recombination Genes in Sulfolobus solfataricus

Keywords: DSB، شکست دو رشته; archaea; Sulfolobus; radiation; DNA repair kinetics; recombinationssDNA, single-strand DNA; IR, ionizing radiation; DSB, double-strand break; HR, homologous recombination; PFGE, pulsed-field gel electrophoresis; NHEJ, nonhomologous end-joining; qRT-PCR, q

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

Spatiotemporal analysis of DNA repair using charged particle radiation

Keywords: DSB، شکست دو رشته; RIF, radiation-induced foci; DSB, double-strand break; LET, linear energy transfer (typical unit: keV/μm); HZE, ions with high energy and high atomic number; Amu, atomic mass units; NHEJ, Non-Homologous End Joining; HR, Homologous Recombination; DDR, DNA

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Inter-individual variation in DNA double-strand break repair in human fibroblasts before and after exposure to low doses of ionizing radiation

Keywords: DSB، شکست دو رشته; A-T, ataxia-telangiectasia; ATM, ataxia-telangiectasia mutated; ATR, ATM and Rad3-related; LIG, ligase; DSB, double-strand break; FANC, Fanconi anemia; IR, ionizing radiation; NBN, nibrin; NBS, Nijmegen breakage syndrome; NHEJ, nonhomologous end joiningγ-

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

A single-strand specific lesion drives MMS-induced hyper-mutability at a double-strand break in yeast

Keywords: DSB، شکست دو رشته; LHM, localized hyper-mutability; ssDNA, single-strand DNA; dsDNA, double-strand DNA; MMS, methyl methanesulfonate; DSB, double-strand break; TLS, DNA translesion synthesis; BER, base excision repair; HR, homologous recombination; NER, nucleotide excision

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Cooperative biological effects between ionizing radiation and other physical and chemical agents

Keywords: DSB، شکست دو رشته; BER, base excision repair; DSB, double-strand break; ELF EMFs, extremely low-frequency electromagnetic fields; IR, ionizing radiation; MN, micronucleus; NER, nucleotide excision repair; SAR, specific absorption rateCombined exposure; Ionizing radiation; E

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Role of oxidatively induced DNA lesions in human pathogenesis

Keywords: DSB، شکست دو رشته; 8-oxo-dG, 8-oxo-2′-deoxyguanosine; BER, base excision repair; DEANO, diethylamine NONOate; DSB, double-strand break; FISH, fluorescent in situ hybridization; Mbp, mega base pair; mtDNA, mitochondrial DNA; NO, nitric oxide; OCDL, oxidative clustered DNA le

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Structural Insight into p53 Recognition by the 53BP1 Tandem Tudor Domain

Keywords: DSB، شکست دو رشته; 53BP1, p53 binding protein 1; PDB, Protein Data Bank; DSB, double-strand break; ChIP, chromatin immunoprecipitation; Fmoc, 9-fluorenylmethoxycarbonylTudor domain; methylated p53; 53BP1; structure; cancer

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

DNA ligase 4 stabilizes the ribosomal DNA array upon fork collapse at the replication fork barrier

Keywords: DSB، شکست دو رشته; ARS, origin of replication; DSB, double-strand break; EM, electron microscopy; ERC, extrachromosomal rDNA circle; HR, homologous recombination; IGS, intergenic spacer; NHEJ, non-homologous end-joining; rDNA, ribosomal DNA; RF, replication fork; RFB, repli

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Consequences of ionizing radiation-induced damage in human neural stem cells

Keywords: DSB، شکست دو رشته; hNSCs, human neural stem cells; γ-H2AX, phospho-histone (Ser139) H2AX; DSB, double-strand break; PARP, poly(ADP-ribose) polymerase; PFA, paraformaldehyde; BrdU, bromodeoxyuridine; ROS, reactive oxygen species; RNS, reactive nitrogen species; CM-H2DCF, 5-(

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Photoactivated multivitamin preparation induces poly(ADP-ribosyl)ation, a DNA damage response in mammalian cells

Keywords: DSB، شکست دو رشته; TPN, total parenteral nutrition; MVP, multivitamin preparation; AA, ascorbic acid; Rib, riboflavin; ROS, reactive oxygen species; BPD, bronchopulmonary dysplasia; SSB, single-strand break; DSB, double-strand break; PARP, poly(ADP-ribose) polymerase; MVP(−

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Cellular pathways for DNA repair and damage tolerance of formaldehyde-induced DNA-protein crosslinks

Keywords: DSB، شکست دو رشته; BER, base excision repair; DPC, DNA-protein crosslink; DSB, double-strand break; NER, nucleotide excision repair; HR, homologous recombination; PFGE, pulsed field gel electrophoresis; SSB, single-strand breakDNA repair; Homologous recombination; Nucleotid

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Choreography of recombination proteins during the DNA damage response

Keywords: DSB، شکست دو رشته; DSB, double-strand break; DSBR, double-strand break repair; HR, homologous recombination; IR, ionizing radiation; MMS, methyl methanesulfonate; NHEJ, non-homologous end-joining; RPA, replication protein A; GFP, green fluorescent protein; CFP, cyan fluores

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

In utero and acute exposure to benzene: Investigation of DNA double-strand breaks and DNA recombination in mice

Keywords: DSB، شکست دو رشته; DSB, double-strand break; GD, gestational day; i.p., intraperitoneal; V(D)J, variable diversity joining; X-gal, 5-bromo-4-chloro-3-indolyl-β-d-galactosideChildhood leukemia; Benzene; DNA double-strand breaks; Micronuclei; Genotoxicity tests

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Regulation of rDNA stability by sumoylation

Keywords: DSB، شکست دو رشته; 4-NQO, 4-nitroquinoline 1-oxide; BIR, break-induced repair; DSB, double-strand break; GC, gene conversion; HR, homologous recombination; IR, ionizing radiation; MMS, methyl methanesulfonate; NHEJ, non-homologous end-joining; rDNA, ribosomal DNA; RFB, repl

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

In vitro complementation of Tdp1 deficiency indicates a stabilized enzyme-DNA adduct from tyrosyl but not glycolate lesions as a consequence of the SCAN1 mutation

Keywords: DSB، شکست دو رشته; Apex1, apurinic/apyrimidinic endonuclease 1; DSB, double-strand break; HRR, homologous recombination repair; IR, ionizing radiation; MEFs, mouse embryonic fibroblasts; NHEJ, non-homologous end-joining; PG, phosphoglycolate; pTyr, phosphotyrosyl; Pnkp, pol

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

DNA-PKcs and ATM co-regulate DNA double-strand break repair

Keywords: DSB، شکست دو رشته; DSB, double-strand break; HR, homologous recombination; NHEJ, non-homologous end-joining; PIK, phosphotidylinositol-3-kinase; IR, ionizing radiationDNA repair; Homologous recombination; Genome stability

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Rag-dependent and Rag-independent mechanisms of Notch1 rearrangement in thymic lymphomas of Atm−/− and scid mice

Keywords: DSB، شکست دو رشته; Atm, ataxia telangiectasia mutated; DSB, double-strand break; IAP, intracisternal A particle; MHEJ, microhomology-mediated end-joining; NHEJ, nonhomologous end-joining; Prkdc, protein kinase, DNA-activated, catalytic subunit; Rag, recombination activating

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Dynamic Regulatory Interactions of Rad51, Rad52, and Replication Protein-A in Recombination Intermediates

Keywords: DSB، شکست دو رشته; RPA, replication protein-A; ssDNA, single-stranded DNA; DSB, double-strand break; HR, homologous recombination; SSA, single-strand annealing; dsDNA, double-stranded DNA; DAPI, 4′,6-diamidino-2-phenylindolehomologous recombination; genome integrity; single

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

DNA Double-Strand Break Formation upon UV-Induced Replication Stress Activates ATM and DNA-PKcs Kinases

Keywords: DSB، شکست دو رشته; ATM, ataxia-telangiectasia mutated; ATR, ataxia-telangiectasia and Rad3 related; DNA-PKcs, DNA-dependent protein kinase catalytic subunit; CPD, cyclobutane pyrimidine dimer; NER, nucleotide excision repair; DSB, double-strand break; ssDNA, single-stranded

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Curcumin derivatives: Molecular basis of their anti-cancer activity

Keywords: DSB، شکست دو رشته; bDMC, bis-DemethoxyCurcumin; DAC, diAcetylCurcumin; MIT, microtubule-targeting agents; BrdU, bromodeoxyuridine; PI, propidium iodide; DMSO, dimethylsulfoxide; DSB, double-strand break; FACS, Fluorescence Activated Cell Sorter; ChIP, Chromatin immunoprecip

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Radioprotective effects of manganese-containing superoxide dismutase mimics on ataxia–telangiectasia cells

Keywords: DSB، شکست دو رشته; A-T, ataxia–telangiectasia; WT, wild type; SOD, superoxide dismutase; IR, ionizing radiation; DSB, double-strand break; IRIF, irradiation-induced immunofluorescent nuclear focus; MnTM-2-PyP5+, manganese(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)por

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه