Induction of homotypic aggregation in the rainbow trout macrophage-like cell line, RTS11
Keywords: Homotypic aggregation; Monocyte/macrophage; RTS11; dsRNA; Integrin; Galectin; PKR
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Homodimeric Structure and Double-stranded RNA Cleavage Activity of the C-terminal RNase III Domain of Human Dicer
Keywords: dsRNA, double-stranded RNA; Ec, Escherichia coli; Gi, Giardia intestinalis; dsRBD, dsRNA-binding domain; Aa, Aquifex aeolicus; Mtb, Mycobacterium tuberculosis; Tm, Thermotoga maritimaRNA interference; Dicer; RNase III enzyme; dsRNA; metal-binding protein
An endornavirus from a hypovirulent strain of the violet root rot fungus, Helicobasidium mompa
Keywords: Helicobasidium mompa; Endornavirus; Helicase; RNA-dependent RNA polymerase; dsRNA; Hypovirulence; UDP glycosyltransferase
Hepatocyte nuclear factor-4α and -1 small interfering RNA inhibits hepatocyte differentiation induced by extracellular matrix
Keywords: ECM; extracellular matrix; EHS; Engelbreth-Holm-Swarm; HNF; hepatocyte nuclear factor; RNAi; RNA interference; dsRNA; double-stranded RNA; siRNAs; small interfering RNAs; RISCs; RNA induced silecing complexes; DIG; digoxigenin; Collagen; Engelbreth-Holm-S
Characterisation of small double stranded RNA molecule in Cryptosporidium hominis, Cryptosporidium felis and Cryptosporidium meleagridis
Keywords: Cryptosporidium; dsRNA; RACE; Reverse transcription–polymerase chain reaction
The p53-induced Wig-1 protein binds double-stranded RNAs with structural characteristics of siRNAs and miRNAs
Keywords: ds, double-stranded; dsRBP, double-stranded RNA binding protein; FL, full-length; GST, glutathione S-transferase; miRNA, micro RNA; NLS, nuclear localization signal; siRNA, small interfering RNA; ss, single-stranded; Tet, tetracyclineWig-1; p53; dsRNA; Zi
Double-stranded RNA induces production of RANTES and IL-8 by human nasal fibroblasts
Keywords: dsRNA; poly(I:C); Chemokine; IL-8; RANTES; Nasal fibroblast
Nasal immunization with a dual antigen anthrax vaccine induced strong mucosal and systemic immune responses against toxins and bacilli
Keywords: Mucosal immunization; Toxin-neutralization; Complement-mediated bacterial killing; dsRNA
Role of epithelial nitric oxide in airway viral infection
Keywords: BALF; bronchoalveolar lavage fluid; CF; cystic fibrosis; cGMP; guanosine 3â²,5â²-cyclic monophosphate; CMV; cytomegalovirus; dsRNA; double-stranded RNA; EPO; eosinophil peroxidase; GAS; γ-activated site; GSH; reduced glutathione; HIV; human immunodefic
Hepatitis C Virus Core Protein Is a Potent Inhibitor of RNA Silencing-Based Antiviral Response
Keywords: dsRNA; double-stranded RNA; HCC; hepatocellular carcinoma; HCV; hepatitis C virus; IRES; internal ribosome entry site; RdRP; RNA-dependent RNA polymerase; RNAi; RNA interference; siRNA; short interfering RNA;
High-throughput approaches to dissecting MAPK signaling pathways
Keywords: High-throughput screen; RNAi; dsRNA; ERK; MAPK; RTK signaling; Data mining; dpERK; Drosophila;
Ebp1 is a dsRNA-binding protein associated with ribosomes that modulates eIF2α phosphorylation
Keywords: Ebp1; dsRNA; Ribosome; eIF2α; PKR; Protein translation
Receptors and ligands involved in viral induction of type I interferon production by plasmacytoid dendritic cells
Keywords: Plasmacytoid dendritic cells; Type I interferon; Viral glycoprotein; DCs; dendritic cells; dsRNA; double-stranded RNA; HA; haemagglutinin; HCMV; human cytomegalovirus; HCV; hepatitis C virus; HEK; human embryonic kidney cells; HIV; human immunodeficiency
The N-terminus of PKR is responsible for the activation of the NF-κB signaling pathway by interacting with the IKK complex
Keywords: PKR; NF-κB; IKK; dsRNA; TLR; Innate immunity
Use of double-stranded RNA templates by the tombusvirus replicase in vitro: Implications for the mechanism of plus-strand initiation
Keywords: Replication; dsRNA; Cucumber necrosis virus; Turnip crinckle virus; RdRp assay; Plus-strand initiation
A mosquito 2-Cys peroxiredoxin protects against nitrosative and oxidative stresses associated with malaria parasite infection
Keywords: AS; Angeli's salt, sodium α-oxyhyponitrite with a molecular formula of Na2(ONNO2); BCP; bacterioferritin comigratory protein; CMV; cytomegalovirus; Ct; threshold cycle; DEA-NO; diethylammonium (Z)-1-(N,N-diethylamino)diazen-1-ium-1,2-diolate with a molec
Molecular characterization of Entamoeba histolytica RNase III and AGO2, two RNA interference hallmark proteins
Keywords: RNAi; RNA interference; siRNA; small interfering RNA; dsRNA; double strand RNA; Gal4AD; Gal4 activation domain; Gal4BD; Gal4 DNA binding domain; Entamoeba histolytica; RNase III; AGO2; RNA interference;
The use of reverse transcriptase for efficient first- and second-strand cDNA synthesis from single- and double-stranded RNA templates
Keywords: dsRNA; RNA virus cloning; cDNA synthesis; Reverse transcriptase;
Serogrouping of United States and some African serotypes of bluetongue virus using RT-PCR
Keywords: Bluetongue virus; dsRNA; RT-PCR; Molecular diagnostics;
The potential of RNA interference as a tool in the management of viral hepatitis
Keywords: RNAi; RNA interference; siRNA; short-interfering ribonucleic acid; dsRNA; double-stranded ribonucleic acid; RISC; RNA-induced silencing complex; shRNA; short hairpin ribonucleic acid; ORF; open reading frame; RT-PCR; reverse transcription-polymerase chain
The developmental role of microRNA in plants
Keywords: AGO; ARGONAUTE; AP2; APETALA2; ARF; auxin response factor; AtXRN4; Arabidopsis thaliana EXORIBONUCLEASE4; CUC; CUP-SHAPED COTYLEDONS; DCL3; DICER-LIKE3; dsRNA; double-stranded RNA; GA; gibberellic acid; HEN1; HUA-ENHANCER1; HST; HASTY; HYL1; HYPONASTIC LE
Absence of non-specific effects of RNA interference triggered by long double-stranded RNA in mouse oocytes
Keywords: RNAi; dsRNA; Oocyte; Interferon response; Off-targeting;
Nucleotide sequence of a mitochondrial RNA virus from the plant pathogenic fungus, Helicobasidium mompa Tanaka
Keywords: Helicobasidium mompa; Mitovirus; Panhandle structure; RNA-dependent RNA polymerase; DsRNA;
RNAi mechanisms in Caenorhabditis elegans
Keywords: RNAi; dsRNA; Gene silencing; Caenorhabditis elegans
Characteristics of nucleic acid TLR ligands
Keywords: DC; dendritic cell; TLR; Toll-like receptor; LPS; Lipopolysaccharides; PAMPs; pathogen-associated molecular patterns; APC; Ag presenting cell; IFN; interferon; PDC; plasmacytoid DC; dsRNA; double-stranded RNA; SLE; systemic lupus erythematosus; RF; rheuma
Analysis of chitin synthase function in a plant parasitic nematode, Meloidogyne artiellia, using RNAi
Keywords: Ct; threshold cycle; dsRNA; double-stranded RNA; RISC; RNA-induced silencing complex; siRNA; short interfering RNA; Gene silencing; Chitin synthase; Parasitic nematodes;
dsRNA formed as an intermediate during Coxsackievirus infection does not induce NO production in a β-cell line with or without addition of IFN-γ
Keywords: Type 1 diabetes; The Coxsackie-adenovirus-receptor; Nitric oxide; dsRNA; β-cell; Enterovirus;
Three unrelated viruses occur in a single isolate of Gremmeniella abietina var. abietina type A
Keywords: Gremmeniella abietina; dsRNA; Mitovirus; Partitivirus; Totivirus;
Evaluation of rotavirus dsRNA load in specimens and body fluids from experimentally infected juvenile macaques by real-time PCR
Keywords: Rotavirus; Rhesus; dsRNA; RT-PCR; Nested PCR; Real-time PCR;
Enhancement of apoptosis via an extrinsic factor, TNF-α, in cells infected with cytopathic bovine viral diarrhea virus
Keywords: Bovine viral diarrhea virus; Apoptosis; Tumor necrosis factor; Inducible nitric oxide synthase; Mucosal disease; BFM; bovine fetal muscle; BVDV; bovine viral diarrhea virus; CP; cytopathic; CPE; cytopathic effect; DMEM; Dulbecco's modified Eagle's medium;
Interferons (IFNs) are key cytokines in both innate and adaptive antiviral immune responses-and viruses counteract IFN action
Keywords: Interferons; Innate antiviral immunity; Interferon-regulatory factor; Toll-like receptors; AP-1; activating protein 1; CARD; caspase recruitment domain; CpG DNA; unmethylated double-stranded DNA; DC; dendritic cell; dsRNA; double-stranded RNA; GAS; IFN ga
Evidence for an evolutionary force that prevents epigenetic silencing between tail-to-tail rice genes with a short spacer
Keywords: EPSPs; 5-enolpyruvylshikimate-3-phosphate synthase; rps20; ribosomal protein small subunit 20; 3â²-UTR; 3â²-untranslated region; PTGS; posttranscriptional gene silencing; wx; waxy; CV; coefficient of variation; dsRNA; double-stranded RNA; RT-PCR; revers
Thogoto virus ML protein suppresses IRF3 function
Keywords: dsRNA; double-stranded RNA; FF-Luc; firefly luciferase; FLUAV; influenza A virus; IFN; interferon; M; matrix protein; ML; matrix protein long; NDV; Newcastle disease virus; NP; nucleoprotein; PFU; plaque forming units; REN-Luc; Renilla luciferase; THOV; T
Identification of two novel human genes, DIPLA1 and DIPAS, expressed in placenta tissue
Keywords: AMV; avian myeloblastosis virus; ASTN2; astrotactin 2; bp; base pair(s); CaM; calmodulin; cDNA; DNA complementary to RNA; DD RT-PCR; differential display RT-PCR; DIPLA1; differentially expressed in placenta 1; DIPAS; DIPLA1 antisense; DPE; downstream prom
In vivo RNA-RNA duplexes from human α3 and α5 nicotinic receptor subunit mRNAs
Keywords: bp; base pair(s); kb; kilobase(s); CHRNA3; cholinergic receptor nicotinic alpha subunit 3; CHRNA5; cholinergic receptor nicotinic alpha subunit 5; CHRNB4; cholinergic receptor nicotinic beta subunit 4; dsRNA; double-stranded RNA; nAChR; nicotinic acetylch
Links between the innate immune system and sleep
Keywords: Sleep; infection; innate immunity; virus; bacteria; toll-like receptors; cytokines; circadian rhythms; stress; asthma; APR; Acute-phase response; dsRNA; Double-stranded RNA; EEG; Electroencephalographic; GHRH; Growth hormone-releasing hormone; NK cells;
Cloning, expression and phylogenetic analysis of Hemolin, from the Chinese oak silkmoth, Antheraea pernyi
Keywords: Hemolin; Chinese oak silkmoth; Antheraea pernyi; Innate immunity; Sequence analysis; Structure prediction; SDS; sodium dodecyl sulfate; dsRNA; double stranded RNA; RNAi; RNA interference; LPS; lipopolysaccharides; PBS; phosphate buffered saline; RT-PCR; r
GCP-2/CXCL6 synergizes with other endothelial cell-derived chemokines in neutrophil mobilization and is associated with angiogenesis in gastrointestinal tumors
Keywords: b-FGF; basic fibroblast growth factor; BSA; bovine serum albumin; CI; chemotactic index; ConA; concanavalin A; dsRNA; double-stranded RNA; ELR; Glu-Leu-Arg; GCP-2; granulocyte chemotactic protein-2; ENA-78; epithelial cell-derived neutrophil attractant-78
GENE impedance: a natural process for control of gene expression and the origin of RNA interference
Keywords: TTRC; Transcription termination/repression complex; TTU; Transcription termination unit; TRU; Transcription repression unit; 3â² UTR; 3â² untranslated region; 3â² AUT; 3â² adjacent untranscribed region; siRNAs; Small interfering RNAs; dsRNA; double-st
Preferential induction of apoptosis in the rainbow trout macrophage cell line, RTS11, by actinomycin D, cycloheximide and double stranded RNA
Keywords: dsRNA; Macrophages; Apoptosis; Ribotoxic stress; PKR; Fish; RTS11; Cell line;
RNA interference: From gene silencing to gene-specific therapeutics
Keywords: RNAi; siRNA; shRNA; Disease; Validation; Therapy; AAV; adeno-associated virus; ABCA1; ATP-binding cassette, subfamily A, member 1; Bcl-2; B-cell chronic lymphocytic leukemia/lymphoma 2; BCR-ABL; breakpoint cluster region-protooncogene tyrosine-protein kin