Keywords: AAV; adeno-associated virus; E2F; E2 transcription factor; FOXO3; Forkhead box protein O3; Nanog; Nanog homeobox transcription factor; NF-κB; nuclear factor-κB; Oct; octamer-binding protein; ODN; oligodeoxynucleotide; Sox; Sox transcription factor (refe
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Keywords: Anti-cancer therapies; Cancer attractors; Cancer stem cells; Hypoxia; Inflammation; Interactome; Metabolic modeling; Networks; Senescence; Signaling; AKT; RAC-alpha serine/threonine protein kinase; BMI1; polycomb ring finger oncogene; C/EBP; CCAAT/enhance
Keywords: Lung adenocarcinoma; Retinoblastoma tumor suppressor protein; Chemotherapy; E2F; Epidermal growth factor receptor
Keywords: Pubchem CID: 444795; Aldh1a2; aldehyde dehydrogenase family 1 member A2; Cdk1; Cyclin-dependent kinase 1, Cdc25, cell division cycle 25; ChIP-seq; chromatin immunoprecipitation followed by next generation sequencing; Crabp1; cellular retinoic acid binding
Keywords: Epigenetics; Phytochemicals; DNA-methylation; Histone-modification; miRNA; Carcinogenesis; Akt; v-akt murine thymoma viral oncogene homolog 1; AP-1; Activator Protein-1; Bax; BCL2-associated X protein; Bcl2; B-cell CLL/lymphoma 2; Bcl-xL; B-cell lymphoma-
Molecular cloning, spatiotemporal and functional expression of GABA receptor subunits RDL1 and RDL2 of the rice stem borer Chilo suppressalis
Keywords: Chilo suppressalis; Electrophysiology; RDL subunits; GABA-gated chloride channel receptor; Spatiotemporal mRNA and heterologous expression; Insecticide actions; ANOVA; analysis of variance; cDNA; complementary DNA; CI; confidence interval; cRNA; capped RN
Transcription Factor E2F3a in Nucleus Accumbens Affects Cocaine Action via Transcription and Alternative Splicing
Keywords: Addiction; ChIP; E2F; Gene expression; RNA sequencing; Splicing;
Transcriptional profiling of the CAM plant Agave salmiana reveals conservation of a genetic program for regeneration
Keywords: CAM; Crassulacean Acid Metabolism; ORF; Opening Reading Frame; NGS; Next-Generation Sequencing; CO2; Carbone Dioxide; PEG; Preferentially Expressed Genes; BAP; 6-benzylaminopurine; CIM; Callus Induction Media; RIN; RNA Integrity Number; FAE; Formaldehyde/
ERK1/2 inhibitors: New weapons to inhibit the RAS-regulated RAF-MEK1/2-ERK1/2 pathway
Keywords: Akt; oncogene in the transforming retrovirus, AKT8; AP-1; activator protein 1; ARAF; v-raf murine sarcoma 3611 viral oncogene homologue; ASK1; apoptosis signal-regulating kinase 1; BCL2; B-cell lymphoma 2; BCL-XL; B-cell lymphoma extra large; BRAF; v-raf
DEPDC1 promotes cell proliferation and tumor growth via activation of E2F signaling in prostate cancer
Keywords: Prostate cancer; DEPDC1; Cell cycle; E2F; Tumorigencity; Bone metastasis;
The phosphatidyl inositol 3 kinase pathway does not suppress activation of the ARF and BIM genes by deregulated E2F1 activity
Keywords: E2F; RB; PI3K; Apoptosis; Gene regulation;
Ectopic expression of the CDK inhibitor p21Cip1 enhances deregulated E2F activity and increases cancer cell-specific cytotoxic gene expression mediated by the ARF tumor suppressor promoter
Keywords: E2F; pRB; ARF; Cancer specific; Suicide gene therapy; Oncolytic virotherapy;
BH3-only protein BIM: An emerging target in chemotherapy
Keywords: A1; Bcl-2-related protein A1; Apaf-1; Apoptotic protease-activating factor 1; ASK1; Apoptosis Signal Regulated Kinase 1; Bad; Bcl-2 associated agonist of cell death; Bak; Bcl-2 homologous antagonist/killer; Bax; Bcl-2-associated X protein; Bcl-2; B-cell l
LXR agonist regulates the proliferation and apoptosis of human T-Cell acute lymphoblastic leukemia cells via the SOCS3 pathway
Keywords: Liver X receptors; Suppressor of cytokine signaling-3; E2F
Functional interaction of CCAAT/enhancer-binding-protein-α basic region mutants with E2F transcription factors and DNA
Keywords: C/EBPα; CCAAT/enhancer-binding protein-α; BRM2; basic region mutation 2; E2F; early gene 2 factor; DP; E2F-dimerization partner; DHFR; dihydrofolate reductase; ACSL1; acyl-CoA synthetase long-chain family member 1; GST; glutathione S-transferase; ITC; i
H19 Noncoding RNA, an Independent Prognostic Factor, Regulates Essential Rb-E2F and CDK8-β-Catenin Signaling in Colorectal Cancer
Keywords: H19; RB1; E2F; CDK8; β-Catenin; Colorectal cancer;
Alternate transcripts of the Drosophila “activator” E2F are necessary for maintenance of cell cycle exit during development
Keywords: E2F; Drosophila; Eye development; Cell cycle;
The evolutionary history of the E2F and DEL genes in Viridiplantae
Keywords: E2F; Plants; Evolutionary history; DNA binding domain; Bayesian analysis;
MicroRNA in prostate cancer
Keywords: DGCR8; Digeorge syndrome chromosomal region 8; CCNDs; cyclin Ds; CDK4; cyclin-dependent kinase 4; CDK6; cyclin-dependent kinase 6; E2F; E2 transcription factor; E2F2; E2 transcription factor 2; IGF1R; insulin-like growth factor 1 receptor; ELK1; ELK1 memb
Regulation of the retinoblastoma–E2F pathway by the ubiquitin–proteasome system
Keywords: Retinoblastoma; RB; p130; p107; E2F; Ubiquitin; Proteasome; Transcription regulation
Disruption of the mevalonate pathway induces dNTP depletion and DNA damage
Keywords: ACN; acetonitrile; BrdU; 5-bromo-2â²-deoxyuridine; DMAPP; dimethylallyl diphosphate; dNs; deoxyribonucleosides; dNTP; deoxyribonucleoside triphosphate; E2F; E2 transcription factor; Fmev; 6-fluoromevalonate; IPP; isopentenyl diphosphate; HU; hydroxyurea;
Proliferating cell unclear antigen-associated factor (PAF15): A novel oncogene
Keywords: APC/C; anaphase-promoting complex/cyclosome; ATF3; transcription factor 3; Bax; B cell lymphoma-associated X; Cdh1; Fizzy/Cell Division Cycle 20 Related 1; CDK; cyclin-dependent kinase; CDT2; chromatin licensing and DNA replication factor 2; CRL4; cytokin
Cancer cell specific cytotoxic gene expression mediated by ARF tumor suppressor promoter constructs
Keywords: E2F; pRB; ARF promoter; E2F1 promoter; Cancer-specific; Normal growing cells;
Regulation of the human ABCB10 gene by E2F transcription factors
Keywords: ABCB10; Promoter; E2F; Transcriptional regulation; Mitochondrial ABC transporters
Modelling cell division and endoreduplication in tomato fruit pericarp
Keywords: CDK; cyclin dependent kinase; CKI; cyclin dependent kinase inhibitor; APC/C; anaphase promoting complex; KRP/ICK; Kip-related protein/Interactor of CDKs, family of CKIs; E2F; family of transcription factors; DP; dimerization partner; DEL; dimerization par
Contrasting roles of E2F2 and E2F3 in endothelial cell growth and ischemic angiogenesis
Keywords: E2F; Endothelial cells; Proliferation; Angiogenesis; Ischemia;
Regulation of the human papillomavirus type 16 late promoter by E7 and the cell cycle
Keywords: Papillomavirus; E7; E2; Differentiation; Late promoter; CDK; E2F;
Azathioprine desensitizes liver cancer cells to insulin-like growth factor 1 and causes apoptosis when it is combined with bafilomycin A1
Keywords: ERK; extracellular signal-regulated kinase; TSC-2; tuberous sclerosis 2 protein; mTOR; mammalian target of rapamycin; IRS; insulin receptor substrate; PI3K; phosphoinositide-3-kinase; AKT; protein kinase B; MAPK; mitogen-activated protein kinase; FOXO1; f
Physiological significance of polyploidization in mammalian cells
Keywords: polyploidization; E2F; hepatocyte; cardiomyocyte; megakaryocyte; trophoblast
MicroRNAs in cancer management and their modulation by dietary agents
Keywords: ACTR1A; ARP1 actin-related protein 1 homolog A centractin alpha; AGTR1; angiotensin II receptor type 1; AICDA; activation-induced cytidine deaminase; AKT; v-akt murine thymoma viral oncogene homolog; ALL; acute lymphocytic leukemia; AML; acute myeloid leu
Arabidopsis G1 cell cycle proteins undergo proteasome-dependent degradation during sucrose starvation
Keywords: Arabidopsis; MM2d cells; RBR; E2F; Sucrose starvation
JNK activation is regulated by E2F and promotes E2F1-induced apoptosis
Keywords: E2F; Apoptosis; JNK
MicroRNAs and the cell cycle
Keywords: E2F; Cancer; Cell cycle; Cyclin; Cyclin-dependent kinase; microRNA; Mitosis; pRB; Transcription
Cell proliferation in the absence of E2F1-3
Keywords: Proliferation; Cell cycle; E2F; Rb; Lens; Repression; Cell survival; Transcription;
Impact of Sodium/Proton Exchanger 3 Gene Variants on Sudden Infant Death Syndrome
Keywords: E2F; General transcription initiation factor; NHE3; Sodium/proton exchanger type 3; NHERF1; NHE regulating factor 1; PCR; Polymerase chain reaction; PP2A; Phosphatase 2A; SIDS; Sudden infant death syndrome;
E2F1 and E2F2 have opposite effects on radiation-induced p53-independent apoptosis in Drosophila
Keywords: Drosophila; Radiation; Apoptosis; p53; E2F
The RB/E2F pathway and regulation of RNA processing
Keywords: RB; Retinoblastoma tumor suppressor; E2F; RNA processing; Pre-mRNA splicing
Expression of E2F transcription factor family genes during chick wing development
Keywords: E2F; Limb; Chick wing; Pattern formation; Growth; Proliferation; Apoptosis; Embryology
Analysis of gene expression in stage I serous tumors identifies critical pathways altered in ovarian cancer
Keywords: Stage I serous carcinoma; Gene expression; Serous borderline tumor; p53; E2F
Identification of PP2A as a novel interactor and regulator of TRIP-Br1
Keywords: TRIP-Br1; PP2A; Protein phosphatase; E2F; Neoplasm
The aryl hydrocarbon receptor cross-talks with multiple signal transduction pathways
Keywords: Aryl hydrocarbon receptor; Phosphorylation; Mitogen-activated kinases; Cell cycle progression; Differentiation; Apoptosis; E2F; RB
DPL-1 (DP) acts in the germ line to coordinate ovulation and fertilization in C. elegans
Keywords: C. elegans; Germline; E2F; Ovulation; Fertilization
E2F-1 overexpression increases viable cell density in batch cultures of Chinese hamster ovary cells
Keywords: Cell cycle; Cell cycle engineering; E2F; E2F-1; Mammalian cell culture; Cell engineering
PEG10 directly regulated by E2Fs might have a role in the development of hepatocellular carcinoma
Keywords: PEG10; E2F; Hepatocelluar carcinoma; Apoptosis
ERK activation is regulated by E2F1 and is essential for E2F1-induced S phase entry
Keywords: E2F; pRB; ERK; MEK; Signal transduction; Transcription;
Positive regulation of the NADPH oxidase NOX4 promoter in vascular smooth muscle cells by E2F
Keywords: Cdks, cyclin-dependent kinases; ChIP, chromatin immunoprecipitation; mASMCs, mouse aortic smooth muscle cells; ROS, reactive oxygen species; VSMC, vascular smooth muscle cellsNOX4; Transcriptional regulation; Promoter; Vascular smooth muscle; E2F
Contribution of extracellular signal-regulated kinases to the IL-1-induced growth inhibition of human melanoma cells A375
Keywords: CDK, cyclin-dependent kinase; ERK, extracellular signal-regulated kinase; ODC, ornithine decarboxylaseCytokines; Melanoma; IL-1; ERK1/2; E2F; CDK; p21; RB
Transcriptional regulation of human polo-like kinases and early mitotic inhibitor
Keywords: polo-like kinase; early mitotic inhibitor; cell cycle; E2F; promoter; gene regulation
Transcriptional regulation of the 5′-flanking region of the human transcription factor Sp3 gene by NF-1, c-Myb, B-Myb, AP-1 and E2F
Keywords: Sp3 promoter; Sp1; Myb; AP-1; NF-1; NF-Y; E2F
1α,25-Dihydroxyvitamin D3-induced down-regulation of the checkpoint proteins, Chk1 and Claspin, is mediated by the pocket proteins p107 and p130
Keywords: Vitamin D; Antiproliferative effects; Chk1; Claspin; E2F; Pocket proteins