Exon 4-skipping GLT-1: A new form of an abundantly expressed glutamate transporter
Keywords: EAAT; Splice-variant; Astrocyte;
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Total oligomeric flavonoids of Cyperus rotundus ameliorates neurological deficits, excitotoxicity and behavioral alterations induced by cerebral ischemic-reperfusion injury in rats
Keywords: AMPA; α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate; ANSA; amino napthol sulphonic acid; ATP; adenosine triphosphates; BHT; butylated hydroxyl toluene; CA; cornu ammonis; CR; Cyperus rotundus; DNPH; dinitrophenyl hydrazine; DTNB; 2,4-dithionitrobenz
Modeling neurodegenerative disease pathophysiology in thiamine deficiency: Consequences of impaired oxidative metabolism
Keywords: AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; AQP-4; aquaporin-4; ATP; adenosine triphosphate; Aβ; amyloid-β peptide; APP; amyloid precursor protein; BBB; blood-brain barrier; BCSFB; blood-cerebrospinal fluid barrier; CT; computed tom
The calcineurin inhibitor, FK506, does not alter glutamate transport in the ischaemic mouse retina
Keywords: Ischemia; neuroprotection; retina; glaucoma; calcineurin; glutamate transporter; EAAT; FK506
Astrocytes: Glutamate transport and alternate splicing of transporters
Keywords: Astrocytes; Glutamate transport; EAAT; Alternate splicing;
Glutamate uptake shapes low-[Mg2+] induced epileptiform activity in juvenile rat hippocampal slices
Keywords: ACSF; artificial cerebrospinal fluid; dl-TBOA; dl-threo-β-benzyloxyaspartate; DHK; dihydrokainic acid; EAAT; excitatory amino acid transporter; Glu; glutamic acid; SLE; seizure-like event; tPDC; l-trans-pyrrolidine-2,4-dicarboxylate; Glu; Glu uptake; Glu
Reduced expression of glutamate transporters vGluT1, EAAT2 and EAAT4 in learned helpless rats, an animal model of depression
Keywords: Depression; EAAT; Glia; Glutamate; Learned helplessness; Transporter
Water transport between CNS compartments: contributions of aquaporins and cotransporters
Keywords: cotransporters; cell swelling; aquaporins; water transport; glial cells; choroid plexus; AQP4; aquaporin 4; CSF; cerebrospinal fluid; EAAT; glutamate transporter; GAT; GABA transporter; KCC; K+/Clâ cotransporter; MCT; monocarboxylate transporter; NKCC;
Regulation of brain aquaporins
Keywords: ANP; atrial natriuretic peptide; AQP; aquaporin; ATP; adenosine triphosphate; BBB; blood-brain barrier; BSE; bovine spongiform encephalopathy; CaMKII; calcium/calmodulin dependent protein kinase II; cAMP; cyclic adenosine monophosphate; cGMP; cyclic gua
Astrocytes are a major target in thiamine deficiency and Wernicke's encephalopathy
Keywords: Thiamine deficiency; Glutamate; Excitotoxicity; Astrocyte; EAAT; Inflammation; Vitamin B1; Oxidative stress
Targeting glial physiology and glutamate cycling in the treatment of depression
Keywords: AANt; amino acid neurotransmitters; AMPA; alpha-amino-3-hydroxy-5-methyl-4-isoxazole-4-propionate; BDNF; brain-derived neurotrophic factor; CREB; cyclic AMP response element binding protein; CUS; chronic unpredictable stress; EAAT; excitatory amino acid t
Functional expression of two system A glutamine transporter isoforms in rat auditory brainstem neurons
Keywords: Slc38a1; Slc38a2; SAT1; SAT2; SNAT1; SNAT2; APV; dl-2-amino-5-phosphonopentanoic acid; BCH; 2-aminobicyclo-[2.2.1]-heptane-2-carboxylic acid; dl-TBOA; dl-threo-b-benzyloxyaspartate; EAAT; excitatory amino acid transporter; GST; glutathione-S-transferase;
Zinc and cortical plasticity
Keywords: 5-HT; 5-hydroxytryptamine; ADP; adenosine diphosphate; AD; Alzheimer's disease; AMPA; α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid; ATP; adenosine triphosphate; BDNF; brain derived neurotrophic factor; Ca-EDTA; calcium ethylenediaminetetraacetic
Glutamate transporter blockade affects Ca2+ responses in astrocytes
Keywords: astrocytes; Ca2+ responses; glutamate; glutamate transporter blockade; glutamate receptors; calcium imaging; [Ca2+]i; intracellular Ca2+ concentration; DMEM/F12HAM; Dulbecco's Modified Eagle's Medium Nutrient Mixture F-12 HAM; EAAT; excitatory amino a
Selective overexpression of excitatory amino acid transporter 2 (EAAT2) in astrocytes enhances neuroprotection from moderate but not severe hypoxia-ischemia
Keywords: hypoxia; ischemia; glutamate transport; ceftriaxone; EAAT2; BSS; balanced salt solution; DHK; dihydrokainic acid; EAAT; excitatory amino acid transport; EAAT2; excitatory amino acid transporter 2; GFAP; glial fibrillary acidic protein; gp; genomic particl
Hydrogen sulfide protects astrocytes against H2O2-induced neural injury via enhancing glutamate uptake
Keywords: AD, Alzheimer's disease; AOAA, amino-oxyacetate; CBS, cystathionine β-synthase; CNS, central nervous system; CSE, cystathionineγ-lyase; DCFH-DA, 2′,7′- dichlorofluorescin diacetate; DMEM, Dulbecco's modified Eagle's medium; DMSO, dimethyl sulphoxide; EAAT
Expression of the exon 9–skipping form of EAAT2 in astrocytes of rats
Keywords: glutamate transporter; EAAT; ALS; white matter; astrocyte; excitotoxicityBSA, bovine serum albumin; EAAT, excitatory amino acid transporter; GFAP, glial fibrillary acidic protein; GLAST, glutamate aspartate transporter; GLT-1, glutamate transporter 1; P,
Changes in glial glutamate transporters in human epileptogenic hippocampus: Inadequate explanation for high extracellular glutamate during seizures
Keywords: Astrocytes; Glutamate; Hippocampus; Temporal lobe epilepsy; MTLE; EAAT; GLAST; GLT-1
GLAST1b, the exon-9 skipping form of the glutamate-aspartate transporter EAAT1 is a sensitive marker of neuronal dysfunction in the hypoxic brain
Keywords: EAAT; excitotoxicity; hypoxia; ischemia; splice; stroke; variant; DAB; 3,3â²-diaminobenzidene; EDTA; ethylenediaminetetraacetic acid; GFAP; flial fibrillary acidic protein; GLAST; glutamate-aspartate transporter; GLT-1; glutamine transporter 1; HRP; hors
Corticosterone inhibits expression of the microglial glutamate transporter GLT-1 in vitro
Keywords: EAAT; glucocorticoid; microglia; lipopolysaccharide; TNF-α; ratANOVA, analysis of variance; BSA, bovine serum albumin; EAAT, excitatory amino acid transporter; ELISA, enzyme-linked immunosorbent assay; FITC, fluorescein isothiocyanate; HEPES, N-(2-hydroxy
Thrombin-stimulated glutamate uptake in human platelets is predominantly mediated by the glial glutamate transporter EAAT2
Keywords: CNS; central nervous system; EAAT; excitatory amino acid transporter; PRP; platelet-rich plasma; Glutamate transport; EAAT2; Blood platelets; Thrombin;
Carbamazepine enhances the activity of glutamate transporter type 3 via phosphatidylinositol 3-kinase
Keywords: cDNA; complementary DNA; CNS; central nervous system; EAAT; excitatory amino acid transporter/glutamate transporter; GABA; γ-aminobutyric acid; IPSC; inhibitory post-synaptic current; PI3K; phosphatidylinositol 3-kinase; PKC; protein kinase C; Carbamazep
Quantitative analysis of immunolabeling for serotonin and for glutamate transporters after administration of imipramine and citalopram
Keywords: Neurotransmitters, modulators, transporters, and receptors, Development and regeneration; Serotonin, Formation and specificity of synapses; 5-HT; Indolamine; Catecholamine; Astrocyte; Neurotransmitter; EAAT; SSRI;
Stimulation of group I metabotropic glutamate receptors evokes calcium signals and c-jun and c-fos gene expression in human T cells
Keywords: iGlu; ionotropic glutamate; mGlu; metabotropic glutamate; NMDA; N-methyl-d-aspartate; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; PLC; phospholipase C; AC; adenylate cyclase; [Ca2+]i; intracellular Ca2+ concentration; mAb; monoclonal anti
Specificity of antibodies: Unexpected cross-reactivity of antibodies directed against the excitatory amino acid transporter 3 (EAAT3)
Keywords: glutamate uptake; immunocytochemistry; polyreactive; antibodies; tubulin; specificity testing; oligodendrocyte; BSA; bovine serum albumin; CHAPS; 3-[(3-cholamido-propyl)dimethylammonio]-1-propanesulphonate; EAAC1; rabbit glutamate transporter (Kanai and H
Excitatory amino acid transporters expressed by synovial fibroblasts in rats with collagen-induced arthritis
Keywords: A.B.; Alcian Blue; AMPA; dl-α-amino-3-hydroxy-5-methylisoxasole-4-propionate; BrdU; 5-bromo-2â²-deoxyuridine; CIA; collagen-induced arthritis; EAAC1; excitatory amino acid carrier-1; EAAT; excitatory amino acid transporter; GAPDH; glyceraldehydes-3-phos
Neuron-Astrocyte Interactions: Partnership for Normal Function and Disease in the Central Nervous System
Keywords: ADP; adenosine diphosphate; ALS; amyotrophic lateral sclerosis; AQP; aquaporin; ATP; adenosine triphosphate; ATPase; adenosine triphosphatase; AVP; arginine vasopressin; BBB; blood-brain barrier; [Ca2+]i; intracellular Ca2+; CBF; cerebral blood flow; CO2;
The excitatory amino acid transporters: Pharmacological insights on substrate and inhibitor specificity of the EAAT subtypes
Keywords: AMPA; (RS)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid; (4S,2ʹS)-APOC; (4S,2ʹS)-2-[2ʹ-aminopropionate]-4,5-dihydro-oxazole-4-carboxylic acid; L-CCG; (carboxycyclopropyl)glycines; EAA; excitatory amino acid; EAAT; excitatory amino acid tra
Macrophages and HIV-1: dangerous liaisons
Keywords: AMM; activated macrophages and microglial cells; APC; antigen-presenting cells; BBB; blood brain barrier; CAF; CD8 antiviral factor; C/EBPβ; CCAAT/enhancer binding protein β; CNF; central nervous system; Cppt; central polypurine tract; EAAT; excitatory