دانلود مقالات ISI درباره Edci + ترجمه فارسی

هیدروکسی تریروسول کلافیبرات چند منظوره جدید با اثرات ضد التهابی، آنتی اکسیدان و هپاتوپروتئین

A new multifunctional hydroxytyrosol-clofibrate with hypolipidemic, antioxidant, and hepatoprotective effects

Keywords: ALP; alkaline phosphatase; ALT; alanine aminotransferase; AST; , aspartate transaminase; CA; clofibric acid; CAT; catalase; CF; clofibrate; CF-HT; hydroxytyrosol-clofibrate 13C NMR, 13C-nuclear magnetic resonance; DMAP; 4-dimethylaminopyridine; DMF; N,N-d

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2018 سفارش ترجمه

سنتز، خصوصیات و اثرات مهاری ترکیبات مشتق شده از سکتین در سرطان و التهاب

Synthesis, characterization and inhibitory effects of crocetin derivative compounds in cancer and inflammation

Keywords: 1H NMR; 1H -nuclear magnetic resonance spectroscopy; 13C NMR; 13C-nuclear magnetic resonance spectroscopy; TCM; traditional Chinese medicine; HRMS; high-resolution mass spectral; HOBt; 1-hydroxy, benzotriazole, hydrate; EDCI; 1-(3-dimethylaminopropyl)-3-e

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

سنتز و بررسی بیولوژیکی آمینوتیازول ها در برابر هیستوپلاسما کپسولاتوم و کریپتوکوک نوورفنس

Synthesis and biological evaluation of aminothiazoles against Histoplasma capsulatum and Cryptococcus neoformans

Keywords: Boc; tert-butyloxycarbonyl; DMAP; 4-dimethylaminopyridine; DCM; dichloromethane; DMF; dimethylformamide; DMSO; dimethyl sulfoxide; EDCI; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide; HIV; human immunodeficiency virus; HOBt; hydroxybenzotriazole; HR-ESI;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

طراحی مبتنی بر ساختار مهارکننده های ترانس گلیکوزیلاز باکتری شامل بفنیل، آمین لینکر و 2-آلکوکسی -3 فسفریل پروپانائو

Structure-based design of bacterial transglycosylase inhibitors incorporating biphenyl, amine linker and 2-alkoxy-3-phosphorylpropanoate moieties

Keywords: Transglycosylase; Moenomycin; Inhibitor; Biphenyl; Phosphorylpropanoate; Amine linker; A. baumannii; Acinetobacter baumannii; Arg; arginine; Asn; asparagine; Asp; aspartic acid; ATCC; american type culture collection; DMF; N,N-dimethylformamide; DMSO; di

دانلود رایگان متن کامل مقاله ISI 77 صفحه سال انتشار : 2018 سفارش ترجمه

آنالوگ های لکتون سوزوکی تریپن را به عنوان عوامل سرطانی ضد سرطان معرفی می کنند

Novel sesquiterpene lactone analogues as potent anti-breast cancer agents

Keywords: Deoxyelephantopin; DET derivatives; Triple-negative breast cancer; Lung metastasis; Paclitaxel; DEAD; diethyl azodicarboxylate; DET; deoxyelephantopin; DETD; deoxyelephantopin derivative; DMAP; dimethylaminopyridine; EDCI; 1-(3-dimethylaminopropyl)-3-ethy

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

توسعه پپتیدهای نوین سیکل به عنوان عوامل پروپوپتوزی

Development of novel cyclic peptides as pro-apoptotic agents

Keywords: Pro-apoptotic agents; Anticancer agents; Cyclic peptides; Peptidomimetics; Nur77; Tubulin; Bcl-2; NMR studies; Molecular modeling; Confocal microscopy; FACS analysis; ADT; AutoDock Tools; COSY; correlation spectroscopy; DBU; 1,8-Diazabicyclo[5.4.0]undec-7

دانلود رایگان متن کامل مقاله ISI 59 صفحه سال انتشار : 2016 سفارش ترجمه

سنتز و ارزیابی بیولوژیکی در مورد کالکوئین های جدید پریازول و دیامید های هتروسیکلیکی جدید به عنوان عوامل ضد سرطان بالقوه

Synthesis and in vitro biological evaluation of new pyrazole chalcones and heterocyclic diamides as potential anticancer agents

Keywords: MCF 7; HeLa; EDCI; HOBt; Diamide

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

سنتز و بررسی بیولوژیکی مشتقات بتولونیک اسید به عنوان عوامل ضد تومور

Synthesis and biological evaluation of betulonic acid derivatives as antitumor agents

Keywords: Betulonic acid derivatives; Synthesis; Antitumor; Apoptosis; Mitochondrial pathway; ADM; adriamycin; AO/EB; acridine orange/ethidium bromide; BetA; betulonic acid; 13C NMR; 13C Nuclear Magnetic Resonance; DMF; N, N-dimethylformamide; DMSO; dimethyl sulfox

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2015 سفارش ترجمه

کشف و بهینه سازی مشتقات کربوکسیلیک اسید آدامانتنی به عنوان مهارکننده های دی سیل گلیسرول آتیل ترانسفراز 1 برای درمان بالقوه چاقی و دیابت

Discovery and optimization of adamantane carboxylic acid derivatives as potent diacylglycerol acyltransferase 1 inhibitors for the potential treatment of obesity and diabetes

Keywords: Obesity; Diabetes; DGAT1; Inhibitor; Adamantane; DGAT; acyl CoA:diacylglycerol acyltransferase; TG; triglyceride; DIPEA; N,N-diisopropylethylamine; OLTT; oral lipid tolerance test; DIO; diet-induced obesity; EDCI; 1-ethyl-3-(3-dimethylaminopropyl)carbodii

دانلود رایگان متن کامل مقاله ISI 73 صفحه سال انتشار : 2015 سفارش ترجمه

ساختار-فعالیت های مرتبط با اکسیکسال آمید ها را به عنوان بازدارنده هیدرولاز اپوکسی محلول در انسان جایگزین کرده است

Structure-activity relationships of substituted oxyoxalamides as inhibitors of the human soluble epoxide hydrolase

Keywords: EETs; epoxyeicosatrienoic acids; sEH; soluble epoxide hydrolase; EDCI; 1-[3-(dimethylamino)propyl]-3-ethyl-carbodiimide; DMAP; 4-dimethylaminopyridine; DMF; N,N-dimethylformamide; CMNPC; cyano-(2-methoxynaphthalen-6-yl)-methyl trans-(3-phenyl-oxyran-2-yl)

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2014 سفارش ترجمه

Design, synthesis, in vitro and in vivo evaluation, and structure-activity relationship (SAR) discussion of novel dipeptidyl boronic acid proteasome inhibitors as orally available anti-cancer agents for the treatment of multiple myeloma and mechanism stud

Keywords: SAR; structureactivity relationship; UPP; ubiquitinproteasome pathway; FDA; Food and Drug Administration; ATP; Adenosine triphosphate; CP; core particle; RP; regulatory proteasome; C-L; caspase-like; T-L; trypsin-like; CT-L; chymotrypsin-like; EDCI; 1-eth

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Design, synthesis and pharmacological evaluation of N-(5-chloro-2,4-dihydroxybenzoyl)-(R)-N-arylmethyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxamides as potent Hsp90 inhibitors

Keywords: Hsp90 inhibitors; CETSA; Molecular dynamics simulation; Apoptosis; IKK; (R)-Tic; (R)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; GA; geldanamycin; BnBr; Benzyl bromide; CETSA; cellular thermal shift assay; DMEM; Dulbecco's modified Eagle's medium; R

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Design and synthesis of aminoester heterodimers containing flavone or chromone moieties as modulators of P-glycoprotein-based multidrug resistance (MDR)

Keywords: P-gp; P-glycoprotein; SAR; Structure-activity relationships; DOX; Doxorubicin; EDCI; 1-(3-dimethylaminopropyl)-3-ethylcarbodiimmide hydrochloride; HOBt; 1-Hydroxybenzotriazole hydrate; DMAP; 4-dimethylaminopyridine; P-gp modulators; MDR reversers; Heterod

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Synthesis and structure-activity relationship studies of MI-2 analogues as MALT1 inhibitors

Keywords: NHL; non-Hodgkin lymphoma; DLBCL; diffuse large B-cell lymphoma; ABC-DLBCL; the activated B cell-like DLBCL; MALT1; mucosa-associated lymphoid tissue protein-1; NF-кB; nuclear factor кB; CARMA1; CARD-containing MAGUK protein 1 (CARD11, caspase recruitme

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Synthesis and evaluation of a novel urea-based 68Ga-complex for imaging PSMA binding in tumor

Keywords: SPECT; single photon emission computer tomography; PET; positron emission tomography; HPLC; High performance liquid chromatography; HRMS; High-resolution mass spectrometry; PBS; phosphate buffered saline; SPE; solid-phase extraction; GMP; good manufacturi

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Structure-guided design, synthesis and evaluation of oxazolidinone-based inhibitors of norovirus 3CL protease

Keywords: PK; pharmacokinetics; DMF; N,N,-dimethylfornamide; DCM; dichloromethane; CDI; carbonyl diimidazole; TLC; thin layer chromatography; EDCI; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide; HOBt; N-hydroxybenzotriazole; DIEA; diisopropylethylamine; DTT; dithio

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Development of inhibitors of receptor protein tyrosine phosphatase β/ζ (PTPRZ1) as candidates for CNS disorders

Keywords: PTPRZ1; CNS disorders; Drug addiction; Molecular dynamics; Synthesis; EDCI; 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide; HOBt; hydroxybenzotriazole; MCPBA; meta-chloroperbenzoic acid; MK; Midkine; PAMPA-BBB; membrane permeability assay for the blood-bra

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

Peramivir conjugates as orally available agents against influenza H275Y mutant

Keywords: Peramivir; Caffeic acid; Conjugate; Neuraminidase; Inhibitor; Influenza; Drug resistance; Ala; alanine; All; allyl; Asn; asparagine; Asp; aspartic acid; CDI; 1,1′-carbonyl diimidazole; DIBAL-H; diisobutylaluminium hydride; DMAP; 4-dimethylaminopyridine;

دانلود رایگان متن کامل مقاله ISI 55 صفحه سال انتشار : 2018 سفارش ترجمه

Rationally designed divalent caffeic amides inhibit amyloid-β fibrillization, induce fibril dissociation, and ameliorate cytotoxicity

Keywords: Amyloid-β; Alzheimer's disease; Caffeic acid; Divalent caffeic amide; Inhibitor; Cytotoxicity; Aβ; amyloid-β; AD; Alzheimer's disease; CA; caffeic acid; CCS; collision cross-section; DMF; dimethylformamide; EDCI; 1-ethyl-3-(3-dimethylaminopropyl) carbo

دانلود رایگان متن کامل مقاله ISI 62 صفحه سال انتشار : 2018 سفارش ترجمه

Synthesis, cytotoxic evaluation and target identification of thieno[2,3-d]pyrimidine derivatives with a dithiocarbamate side chain at C2 position

Keywords: Thieno[2,3-d]pyrimidine; Dithiocarbamate; Cytotoxicity; Probe; Target identification; Tubulin; Boc; tert-butyloxycarbonyl; CPT; camptothecin; DMF; N,N-dimethylformamide; DMSO; dimethyl sulphoxide; DSB; DNA double-strand break; EDCI; 1-ethyl-3-(3-dimethyla

دانلود رایگان متن کامل مقاله ISI 70 صفحه سال انتشار : 2018 سفارش ترجمه

Activity cliff for 7-substituted pyrrolo-pyrimidine inhibitors of HCK explained in terms of predicted basicity of the amine nitrogen

Keywords: EDCI; 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide; HATU; 1-[bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate; HCK; hematopoietic cell kinase; HOBt; hydroxybenzotriazole; NABH(OAc)3; sodium triacetoxyborohydride;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

2-Naphthoic acid ergosterol ester, an ergosterol derivative, exhibits anti-tumor activity by promoting apoptosis and inhibiting angiogenesis

Keywords: ER; ergosterol; EDCI; 1-ethyl-3-(3-dimethyllaminopropyl) carbodiimide hydrochloride; CTX; cyclophosphamide; TLC; thin-layer chromatography; IFN-γ; interferon-γ; VEGF; vascular endothelial growth factor; ALT; alanine aminotransferase; AST; aspartate tran

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis and evaluation of novel ureido/thioureido derivatives of amino acid conjugated 2,3-dichlorophenyl piperazine as highly potent antiglycating agents

Keywords: AGE; advanced glycation end products; Boc; t-butoxycarbonyl; BSA; bovine serum albumin; EDCI; 1-(3-dimethylaminopropyl)-3-ethyl-carbodiimide·HCl; HOBt; 1-hydroxybenzotriazole; NMM; N-methyl morpholine; PBS; phosphate buffer saline; PZN; 1-(2,3-dichloroph

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

2-Aminomethylthieno[3,2-d]pyrimidin-4(3H)-ones bearing 3-methylpyrazole hinge binding moiety: Highly potent, selective, and time-dependent inhibitors of Cdc7 kinase

Keywords: CPME; cyclopentyl methyl ether; DCM; dichloromethane; DMA; N,N-dimethylacetamide; DMAP; 4-dimethylaminopyridine; DME; 1,2-dimethoxyethane; DMF; N,N-dimethylformamide; DMSO; dimethyl sulfoxide; EDCI; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochlor

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery of pentacyclic triterpene 3β-ester derivatives as a new class of cholesterol ester transfer protein inhibitors

Keywords: CETP inhibitor; Pentacyclic triterpenes; Non-HDL-C; Dyslipidemia; CVDs; cardiovascular diseases; CETP; cholesteryl ester transfer protein; HDL-C; high density lipoprotein-cholesterol; LDL-C; low density lipoprotein-cholesterol; VLDL; very-low-density lipo

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Identification of a new class of potent Cdc7 inhibitors designed by putative pharmacophore model: Synthesis and biological evaluation of 2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-ones

Keywords: Cell division cycle 7 (Cdc7); Pharmacophore model; Dihydrothieno[3,2-d]-pyrimidin-4(1H)-one; CSA; (+/−)-camphor-10-sulfonic acid; DCM; dichloromethane; DMA; N,N-dimethylacetamide; DME; 1,2-dimethoxyethane; DMF; N,N-dimethylformamide; DMSO; dimethyl sulf

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

New bis(hydroxymethyl) alkanoate curcuminoid derivatives exhibit activity against triple-negative breast cancer in vitro and in vivo

Keywords: Antiproliferative agents; Antitumor agents; Bis(hydroxymethyl) alkanoate curcuminoids; Curcumin; Triple-negative breast cancer; BUN; blood urea nitrogen; DMAP; N,N-dimethylaminopyridine; DMF; dimethylformamide; DMSO; dimethylsulfoxide; EtOAc; ethyl acetat

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

4-Hydroxy-N-propyl-1,8-naphthalimide esters: New fluorescence-based assay for analysing lipase and esterase activity

Keywords: Carboxylester hydrolase; Enzyme assay; Fluorescence; Lipase; 1,8-Naphthalimide; BSA; bovine serum albumin; CalA; Candida antarctica lipase A; CalB; Candida antarctica lipase B; DMAP; 4-dimethylaminopyridine; DMSO; dimethyl sulfoxide; EDCI; 1-ethyl-3-(3-di

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Analogues of DNA minor groove cross-linking agents incorporating aminoCBI, an amino derivative of the duocarmycins: Synthesis, cytotoxicity, and potential as payloads for antibody-drug conjugates

Keywords: ADC; antibody-drug conjugate; BINAP; 2,2′-bis(diphenylphosphino)-1,1′-binaphthalene; CBI; 1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one; EDCI; N-ethyl-N′-(3-dimethylaminopropyl)carbodiimide hydrochloride; MMAE; monomethyl auristatin E; PBD; p

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Functional evaluation of fluorescein-labeled derivatives of a peptide inhibitor of the EGF receptor dimerization

Keywords: DIPEA; N,N-diisopropylethylamine; EDCI; 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide; DMF; dimethylformamide; EDT; ethanedithiol; HOBt; 1-hydroxybenzotriazole; TFA; trifluoroacetic acid; TIS; triisopropylsilane; EGF; epidermal growth factor; TGF; transfo

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

A pH-sensitive hyaluronic acid prodrug modified with lactoferrin for glioma dual-targeted treatment

Keywords: ADH; adipic acid dihydrazide; ANOVA; one-way analysis of variance; ATCC; American Type Culture Collection; BBB; blood brain barrier; BTB; blood-tumor barrier; CCK-8; Cell Counting Kit-8; DMEM; Dulbecco's modified Eagle's medium; DOX; doxorubicin; EDCI; 1-

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Structure-activity relationship study of syringolin A as a potential anticancer agent

Keywords: Fmoc; 9-fluorenylmethyloxycarbonyl; EDCI; 1-ethyl-3-(3-dimethylaminopropyl)carboxamide; HOBt; 1-hydroxybenzotriazole; DMF; N,N-dimethylformamide; Proteasome inhibitor; Cancer; Structure-activity relationship;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Synthesis, biological evaluation and docking analysis of a new series of methylsulfonyl and sulfamoyl acetamides and ethyl acetates as potent COX-2 inhibitors

Keywords: AA; arachidonic acid; CMC; carboxymethylcellulose; COX; cyclooxygenase; Coxibs; COX-2 selective inhibitors; Das; accuracies percentages; DIPA; diisopropylamine; DMAP; dimethylaminopyridine; EDCI; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide; EIA; enzyme

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Novel benzidine and diaminofluorene prolinamide derivatives as potent hepatitis C virus NS5A inhibitors

Keywords: HCV; NS5A inhibitor; Benzidine; Diaminofluorene; Structure-activity relationship; HCV; hepatitis C virus; Peg-IFNα; pegylated interferon α; SVR; sustained virological response; GT1a; hepatitis C virus genotype 1a, a subtype of hepatitis C virus genoty

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

BN/CC isosterism in borazaronaphthalenes towards phosphodiesterase 10A (PDE10A) inhibitors

Keywords: cAMP; cyclic adenosine monophosphate; cGMP; cyclic guanosine monophosphate; Boc; tert-butyloxycarbonyl; THF; tetrahydrofuran; DMF; dimethylformamide; CPME; cyclopentyl methyl ether; TFA; trifluoroacetic acid; EDCI; 1-ethyl-3-(3-dimethylaminopropyl)carbodi

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Binding cooperativity between a ligand carbonyl group and a hydrophobic side chain can be enhanced by additional H-bonds in a distance dependent manner: A case study with thrombin inhibitors

Keywords: Cooperativity; Protein-ligand binding; Ligand binding affinity; Scoring functions; B-factor; Thrombin; Non-additivity; Me; methyl; Bn; benzyl; Boc; tert-butoxycarbonyl; ΔG˚; standard Gibbs free energy; Ki; inhibition constant; EDCI; 1-(3-dimethylaminopr

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2015 سفارش ترجمه

(−)-Meptazinol-melatonin hybrids as novel dual inhibitors of cholinesterases and amyloid-β aggregation with high antioxidant potency for Alzheimer's therapy

Keywords: AD; Alzheimer's disease; Aβ; amyloid-β; ACh; acetylcholine; AChE; acetylcholinesterase; AChEIs; acetylcholinesterase inhibitors; BChE; butyrylcholinesterase; BBB; blood-brain barrier; CAS; catalytic anionic site; ChEs; cholinesterases; CCK-8; cell c

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2015 سفارش ترجمه

Design, synthesis, and immunologic evaluation of vaccine adjuvant conjugates based on QS-21 and tucaresol

Keywords: AS; adjuvant systems; MPL; monophosphoryl lipid A; QS; Quillaja saponaria; EDCI; N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride; NHS; N-hydroxysuccinimide; KLH; keyhole limpet hemocyanin; MUC1; mucin-1; OVA; ovalbumin; MBS; m-maleimidobenz

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Discovery of a new HIV-1 inhibitor scaffold and synthesis of potential prodrugs of indazoles

Keywords: CDKs; cyclin-dependent kinases; CKII; casein kinase 2; DMAP; dimethylaminopyridine; EDCI; N-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride; LIMK; LIM kinases; PK; pharmacokinetics; TFA; trifluoroacetic acid; HIV; Drug target; Oxazoles; Prodrugs

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Biologically active ester derivatives as potent inhibitors of the soluble epoxide hydrolase

Keywords: sEH; soluble epoxide hydrolase; EET; epoxyeicosatrienoic acid; EDCI; 1-[3-(dimethylamino)propyl]-3-ethylcarbodiimide; DMAP; 4-dimethylaminopyridine; sEH; sEH inhibitors; Substituted urea-ester derivatives; Metabolic stability;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Synthesis and evaluation of nitric oxide-releasing DDB derivatives as potential Pgp-mediated MDR reversal agents in MCF-7/Adr cells

Keywords: DDB; dimethyl-4,4′-dimethoxy-5,6,5′,6′-dimethylenedioxybiphenyl-2,2′-dicarboxylate; NO; nitric oxide; MDR; multidrug resistance; VER; Verapamil; Dox; doxorubicin; EDCI; 1-(3-dimethyl aminopropyl)-3-ethylcarbodiimide hydrochloride; DMAP; 4-dimethyl

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Anthelmintic PF1022A: stepwise solid-phase synthesis of a cyclodepsipeptide containing N-methyl amino acids

Keywords: ACN; acetonitrile; Boc; tert-butyloxycarbonyl; BOPCl; N,N′-bis(2-oxo-3-oxazolidinyl)phosphinic chloride; DCM; dichloromethane; DEAD; diethylazodicarboxylate; DHP; 3,4-dihydro-2H-pyrane; DIC; N,N′-diisopropylcarbodiimide; DIEA; diisopropylethylamine; D

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

The discovery and synthesis of JNJ 31020028, a small molecule antagonist of the Neuropeptide Y Y2 receptor

Keywords: DCM; dichloromethane; HOBt; 1-hydroxy-benzotriazole; EDCI; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide; BOC; butoxycarbonyl; MeOH; methanol; K2CO3; potassium carbonate; Na2CO3; sodium carbonate; DMF; dimethylformamide; Et3N; triethylamine; Et2O; ether;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Hypoxic selectivity and solubility-investigating the properties of A-ring substituted nitro seco-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-ones (nitroCBIs) as hypoxia-activated prodrugs for antitumor therapy

Keywords: AUC; area under the concentration-time curve; CBI; seco-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one; DEI; 5-[(dimethylamino)ethoxy]indole; EDCI; N-ethyl-N′-(3-dimethylaminopropyl)carbodiimide hydrochloride; EWG; electron-withdrawing group; HAP;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Stability of responsive polymer-protein bioconjugates

Keywords: AADG; acrylamide-2-deoxy-D-glucose; AIBN2; 2′-azobisisobutyronitrile; ATRP; atom transfer radical polymerization; CDs; cyclodextrins; CRL; Candida-rugosa lipase; CRP; controlled radical polymerization; DMSO; dimethyl sulphoxide; EDCI; 1-ethyl-3-(3-dieth

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2010 سفارش ترجمه

Synthesis of the chlorofusin cyclic peptide

Keywords: Ada; 2-aminodecanoic acid; EDCI; 1-ethyl-3-(3-dimethylamino-propyl)carbodiimide; HOAt; 1-hydroxy-7-azabenzotriazole; MDM2; murine double minute 2 protein; p53; protein 53; SES; 2-(trimethylsilyl)ethylsulfonyl; Trt; trityl (triphenylmethyl);

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Recent advances in the chemistry of macroline, sarpagine and ajmaline-related indole alkaloids

Keywords: Ac; acetyl; AD; asymmetric dihydroxylation; AIBN; 2,2′-azobisisobutyronitrile; Ar; aryl; 9-BBN; 9-borabicyclo[3.3.1]nonane; Bn; benzyl; Boc; tert-butoxycarbonyl; Bu; butyl; Bz; benzoyl; cat; catalytic; CBz; benzyloxycarbonyl; CLB; chlorobenzoyl; Cy; cyc

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2006 سفارش ترجمه

The 2-aminoglucosamide motif improves cellular uptake and photodynamic activity of tetraphenylporphyrin

Keywords: Photodynamic therapy; Glucosylation; Porphyrin; Chlorin; Targeting; In vitro; ATP; adenosine triphosphate; Boc; tert-butoxycarbonyl; BSA; bovine serum albumin; CDCl3; chloroform-d; CH2Cl2; dichloromethane; DCC; dicyclohexylcarbodiimide; DDQ; 2,3-dichloro

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Use of O-glycosylation in total synthesis

Keywords: O-Glycosylation; Total synthesis; Ac; acetyl; ACF; activated carbon fiber; AIBN; 2,2′-azobiisobutyronitrile; Alloc; allyloxycarbonyl; Ar; aryl; AtOH; 7-aza-1-hydroxy-1H-benzotriazole; BF3(Et2O); boron trifluoride etherate; DMB; 3,4-dimethoxybenzyl; DMTS

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2005 سفارش ترجمه

Sulfide- and selenide-based linkers in phase tag-assisted synthesis

Keywords: Solid phase; Linkers; Sulfur; Selenium; AIBN; 2,2′-azobis(2-methylpropionitrile); Alloc; allyloxycarbonyl; Boc; t-butoxycarbonyl; Cbz; benzyloxycarbonyl; CSA; 10-camphorsulfonic acid; DABCO; diazabicyclo[2.2.2]octane; DAST; diethylaminosulfur trifluorid

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2005 سفارش ترجمه