
Targeting PERK signaling with the small molecule GSK2606414 prevents neurodegeneration in a model of Parkinson's disease
Keywords: استرس است; PD; Parkinson's disease; SNpc; substantia nigra pars compacta; PrDs; prion-related disorders; UPR; unfolded protein response; ISR; integrated stress response; PERK; RNA-like ER kinase; ATF4; activating of transcription-4; ATF3; activating of transcription