Keywords: Biphalin; Opioid receptors; MOR/DOR/KOR agonist; Synergistic analgesic effect; Cyclic peptides; Acm; acetamidomethyl; ACN; acetonitrile; BBB; blood brain barrier; Boc; t-butyloxycarbonyl; BOP; (benzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluoro
مقالات ISI (ترجمه نشده)
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Keywords: DHA; dihydroartemisinin; DMAP; 4-(dimethylamino)-pyridine; DCC; N,Nâ²-dicyclohexylcarbodiimide; DIAD; diisopropyl azodicarboxylate; EC50; half maximal effective concentration; EtOAc; ethylacetate; eq; equivalent; HCMV; human cytomegalovirus; TMSOTf; trim
Keywords: CEC; contaminants of emerging concern; DMSO; dimethylsulfoxide; EC50/20; concentration which causes 50% (20%) growth rate inhibition of algae compared to solvent control; EDA; effect directed analysis; EtOAc; ethylacetate; GC(xGC)-MS; (two dimensional) ga
Keywords: 6-[(3-methylbut-2-en-1-yl)amino]purine; N6-isopentenyladenine; Isoprenoid; Cytokinin; Fluorescent label; Fluorescent probe; Linker; Competitive receptor bioassay; ARR5:GUS; Live cell confocal microscopy; ABA; abscisic acid; 2-AmEtAm; 2-aminoethylamino-; 6
Keywords: BHA; butylated hydroxyanisole; BHT; butylated hydroxytoluene; EtOAc; ethyl acetate; GAE/g fw; mg of gallic acid equivalents per gram of fresh weight; TFC; total flavonoid content; TPC; total phenolic content; QE/g fw; mg of quercetin equivalents per gram
Keywords: AcOH; acetic acid; ACN; acetonitrile; APCI; atmospheric pressure chemical ionization; BSTFA; N,O-bis(trimethylsilyl)trifluoroacetamide; CBCA; cannabichromenic acid; CBC; cannabichromene; CBDA; cannabidiolic acid; CBD; cannabidiol; CBDVA; cannabidivarinic
Keywords: OPC; oligomeric proanthocyanidin; MeOH; methanol; EtOH; ethanol; EtOAc; ethyl acetate; AcOH; acetic acid; DMTSF; dimethyl (methylthio) sulfonium tetrafluoroborate; DDQ; 2,3-dichloro-5,6-dicyano-p-benzoquinone; DMAP; 4-(dimethylamino)pyridine; EMEM; Eagleâ
Keywords: BAPC; bioreductively activatable prodrug conjugate; CA1; combretastatin A-1; CA4; combretastatin A-4; Et3N; triethylamine; HPLC; high performance liquid chromatography; HRMS; high resolution mass spectrometry; MeOH; methanol; NaBH4; sodium borohydride; TL
Keywords: DM; diabetes mellitus; LD50; lethal dose that killed 50% of the rats; bg; blood glucose; FBG; fasting blood glucose; To; 0Â h; TLC; thin layer chromatography; 1H NMR; proton nuclear magnetic resonance spectroscopy; 13C NMR; carbon-13 nuclear magnetic reso
Keywords: MMP; matrix metalloproteinase; MMP-9; matrix metalloproteinase-9; TIMP; tissue inhibitors of matrix metalloproteinase; DMSO; dimethyl sulfoxide; BuOH; butanol; CHCl3; chloroform; EtOAc; ethyl acetate; CC; (+)-catechin; EC; (â)-epicatechin; ECG; (â)-ep
Immunoaffinity chromatography combined with tandem mass spectrometry: A new tool for the selective capture and analysis of brassinosteroid plant hormones
Keywords: Ab; antibody; BRs; brassinosteroids; HRP; horseradish peroxidase; IAC; immunoaffinity chromatography; IAG; immunoaffinity gel; ELISA; enzyme-linked immunosorbent assay; EtOAc; ethyl acetate; Et3N; triethylamine; mAb; monoclonal antibody; SPE; solid phase
Synthesis, characterization, and application of a novel multifunctional stationary phase for hydrophilic interaction/reversed phase mixed-mode chromatography
Keywords: HPLC; High-Performance Liquid Chromatography; RPLC; Reversed-Phase Liquid Chromatography; HILIC; Hydrophilic Interaction Liquid Chromatography; DCC; Dicyclohexylcarbodiimide; HOBT; 1-Hydroxybenzotriazole hydrate; DCM; Dichloromethane; H; Hexane; EtOAc; Et
Keywords: 13DC2P; 1,3-dichloro-2-propanol; 22BBM13P; 2,2-bisbromomethyl-1,3-propanediol; 23DB1P; 2,3-dibromo-1-propanol; 4,4â²-DDT; 4,4â²-DDT dichlorodiphenyltrichloroethane; ACE; acetone; AER; air exchange rate; AHTN; 6-acetyl-1,1,2,4,4,7-hexamethyltetralin (Ton
Keywords: MRSA; methicillin-resistant Staphylococcus aureus; MSSA; methicillin-sensitive S. aureus; AIDS; acquired-immuno deficiency syndrome; SLNs; solid lipid nanoparticles; RT; room temperature; EDAC.HCl; N-(3-dimethylaminopropyl)-Nâ²-ethylcarbodiimide hydrochl
Keywords: CAM; Complementary and Alternative Medicine; GI50; growth inhibition 50%; ED50; effective dose; IC50; inhibitory concentration 50%; EtOH; ethanol extract; Hex; hexane extract; EtOAc; ethylacetate extract; MeOH; methanol extract; DCM; Dichloromethane; PE;
Keywords: MeCN; acetonitrile; CL; clearance; Dess-Martin periodinane; 1,1,1-tris(acetyloxy)-1,1-dihydro-1,2-benziodoxol-3-(1H)-one; DIBALH; diisobutylaluminum hydride; DMF; N,N-dimethylformamide; EtOAc; ethyl acetate; HBTU; N,N,Nâ²,Nâ²-tetramethyl-O-(1H-benzotr
Keywords: CH2Cl2; dichloromethane; EtOAc; ethyl acetate; MIC; minimum inhibitory concentration; MTT; 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide; DiSC3(5); 3,3â²-dipropylthiacarbocyanine; SD; standard deviation; GUV; giant unilamellar vesicle;
Keywords: ADME; absorption/distribution/metabolism/excretion; BBB; blood-brain barrier; CD3OD; tetradeuteromethanol; CDCl3; deuterochloroform; CH2Cl2; dichloromethane; C log D; distribution coefficient; C log P; calculated partition coefficient; CNS; central
Keywords: ABAP; 2,2â²-azobis-amidinopropane; CAA; cellular antioxidant activity; DCFH-DA; 2,7-diacetate dichlorofluorescin; EtOAc; ethyl acetate; GSH-Px; glutathione peroxidase; ORAC; radical absorption capacity; PSC; peroxyl radical scavenging capacity; Litchi le
Keywords: Obesity; Diabetes; DGAT1; Inhibitor; Adamantane; DGAT; acyl CoA:diacylglycerol acyltransferase; TG; triglyceride; DIPEA; N,N-diisopropylethylamine; OLTT; oral lipid tolerance test; DIO; diet-induced obesity; EDCI; 1-ethyl-3-(3-dimethylaminopropyl)carbodii
Keywords: (±)-BINAP; (±)-2,2â²-bis(diphenylphosphino)-1,1â²-binaphthalene; cLogP; calculated partition coefficient; COX; cyclooxygenase; CYP; cytochrome P450 for a specific isoform; DCM; dichloromethane; ELISA; enzyme-linked immunosorbent assay; EtOAc; ethyl ac
Keywords: Antitubercular activity; Isoniazid derivatives; Mycobacterium tuberculosis; Resistance; QSARs; Synthesis; AE; average error; AAE; absolute average error; ASNNs; associative neural networks; BCG; Bacillus Calmette-Guérin; CCC; concordance correlation co
Keywords: CPC; centrifugal partition chromatography; IC50; inhibition concentration at 50 percent; BHT; butylated hydroxytoluene; BHA; butylated hydroxyanisole; n-hept; n-heptane; EtOAc; ethyl acetate; MeOH; methanol; TFA; trifluoroacetic acid; MeCN; Acetonitrile;
Synthetic and in vitro studies to indicate that the structure of the PTP1B inhibitor isolated from Acanthopanax senticosus requires reinvestigation
Keywords: ATR; attenuated total reflectance; ESI; electrospray ionization; EtOAc; ethyl acetate; IR; infrared; PTP1B; protein tyrosine phosphatase 1B; PTP1B inhibitor; Acanthopanax senticosus; Ullmann ether synthesis; Diphenyl ether oxyneolignan;
Quantitative analysis of the cyclic peptide GG-8-6 in rat plasma using LC-MS/MS and its application to a pharmacokinetic study
Keywords: LC-MS/MS; liquid chromatographic method with tandem mass spectrometric detection; HCC; hepatocellular carcinoma; GG-8-6; cyclo-(Val1-Leu2-Pro3-Ile4-Leu5-Leu6-Leu7-Val8-Leu9); UV; ultraviolet; IS; internal standard; A6; cyclo-(Val1-Leu2-Pro3-Ala4-Leu5-Leu6
Evaluation of a one-step sample preparation protocol for analysis of total serum testosterone by LC-MS/MS
Keywords: 4-dione; androstenedione; 5-diol; androst-5-ene-3β,17β-diol; Cl-butane; 1-chlorobutane; DHEA; dehydroepiandrosterone; DHT; dihydrotestosterone; Endo HQC; endogenous high quality control; Endo LQC; endogenous low quality control; Endo MQC; endogenous med
Pistafolin B is the major aldose reductase inhibitor of the pods of tara [Caesalpinia spinose (Molina) Kuntze]
Keywords: 1H NMR; proton nuclear magnetic resonance; ANOVA; one-way analysis of variance; AR; aldose reductase; ARI; aldose reductase inhibitor; CH2Cl2; methylene chloride; EI-MS; electron ionization mass spectrometry; EtOAc; ethyl acetate; FBS; foetal bovine serum
Anti-inflammatory diarylheptanoids and phenolics from the rhizomes of kencur (Kaempferia galanga L.)
Keywords: COSY; correlation spectroscopy; DEPT; distortionless enhancement by polarization transfer; EtOAc; ethyl acetate; EtOH; ethanol; GC; gas chromatography; HPLC; high-performance liquid chromatography; HR-ESI-MS; high-resolution electrospray mass spectrum; HS
Discovery and evaluation of nNav1.5 sodium channel blockers with potent cell invasion inhibitory activity in breast cancer cells
Keywords: CDCl3; Deuterated chloroform; CH2Cl2; Methylene dichloride; 13C NMR; Carbon-13 nuclear magnetic resonance; CoMFA; Comparative molecular field analysis; CuBr.Me2S; Copper bromide dimethyl sulfide; DMEM; Dulbecco's modified eagle medium; DMSO; Dimethyl sulf
Plasma pharmacokinetics and cerebral nuclei distribution of major constituents of Psoraleae fructus in rats after oral administration
Keywords: Psoraleae fructus; Pharmacokinetics; Cerebral nuclei distribution; Coumarins; Prenylflavonoids; LC-MS/MS; ACN; acetonitrile; AUC; area under curve; Aβ42; β-amyloid 42; CE; collision energy; Cmax; maximum drug concentration; CMC-Na; carboxymethyl cellulo
A comparative assessment of continuous production techniques to generate sub-micron size PLGA particles
Keywords: PLGA; poly(lactic-co-glycolic acid); API; active pharmaceutical ingredient; GMP; good manufacturing practice; DCM; dichloromethane; EtOAc; ethyl acetate; ACN; acetonitrile; PVA; polyvinyl alcohol; FRR; flow rate ratio; TFR; total flow rate; Poly(lactic-co
Synthesis and in vitro characterization of a P2X7 radioligand [123I]TZ6019 and its response to neuroinflammation in a mouse model of Alzheimer disease
Keywords: ACN; Acetonitrile; AD; Alzheimer's disease; AMF; ammonium formate; ATP; adenosine-triphosphate; BzATP; 3â²-O-(4-Benzoyl)benzoyl ATP, strong agonist for P2X7 receptor; CNS; central nervous system; DMEM; Dulbecco's Modified Eagle's Medium; DMF; dimethylfor
Synthesis and pharmacological characterization of functionalized 6-piperazin-1-yl-purines as cannabinoid receptor 1 (CB1) inverse agonists
Keywords: BBB; Blood-Brain Barrier; CB1; Cannabinoid Receptor 1; CB2; Cannabinoid Receptor 2; CHO-K1; Chinese Hamster Ovary Cells; CNS; Central Nervous System; EtOH; ethanol; EtOAc; ethyl acetate; Ke; apparent affinity constant, MDCK-mdr1, Madin-Darby canine kidney
Physalis alkekengi L. var. franchetii (Mast.) Makino: An ethnomedical, phytochemical and pharmacological review
Keywords: ERK; extracellular signal-regulated kinase; EtOAc; ethyl acetate; EtOH; ethyl alcohol; COX-2; cyclooxygenase-2; IL; interleukin; INF-γ; interferon γ; JAK; Janus kinases; LPS; lipopolysaccharide; MAPK; mitogen-activated protein kinase; MIC; minimum inhib
Discovery of novel piperonyl derivatives as diapophytoene desaturase inhibitors for the treatment of methicillin-, vancomycin- and linezolid-resistant Staphylococcus aureus infections
Keywords: CrtN inhibitor; STX biosynthesis; Pigment inhibitory activity; Resistant S. aureus; S. aureus; Staphylococcus aureus; MRSA; methicillin-resistant Staphylococcus aureus; STX; staphyloxanthin; NTF; naftifine hydrochloride; CrtM; dehydrosqualene synthase;
Antibiotic-potentiating activity, phytochemical profile, and cytotoxicity of Acalypha integrifolia Willd. (Euphorbiaceae)
Keywords: AI; A. integrifolia; Chlo; chloroform; MeOH; methanol; DCM; dichloromethane; EtOAc; ethyl acetate; EC; Escherichia coli; SA; Staphylococcus aureus; ST; Salmonella typhimurium; VP; Vibrio parahaemolyticus; AC; Acinetobacter spp; KL; Klebsiella spp; PA; Pse
Pharmacokinetics and cytotoxic study of euphol from Euphorbia umbellata (Bruyns) Pax latex
Keywords: Euphol; Cell culture; Cytotoxic activity; UHPLC-MS; Euphorbia; Pharmacokinetics; 1D and 2D NMR; one and two dimension nuclear magnetic resonance spectroscopy; ACN; acetonitrile; ATCC; american type culture collection; CDCl3; deuterated chloroform; CDK; cy
Ethnobotany, phytochemistry and pharmacology of Arctotis arctotoides (L.f.) O. Hoffm.: A review
Keywords: ABTS; 2, 2'-azino-bis 3-ethylbenzothiazoline-6-sulphonic acid; BHT; butylated hydroxytoluene; Ca; Calcium; CC; column chromatography; COX-2; cyclooxygenase-2; DPPH; 2,2-diphenyl-1-picrylhydrazyl; EDXS; energy-dispersive X-ray spectroscopy; EtOH; ethanol;
St John's wort (Hypericum perforatum) products - an assessment of their authenticity and quality
Keywords: Quality control; Value chains,; Traditional Herbal Registration (THR); Avicularin/guaijaverin; St John's wort; Hypericum perforatum; ADC; automatic developing chamber; AV; avicularin; BRM; botanical reference material; DCHA; dicyclohexylamine; DCM; dichlo
A promising natural product, pristimerin, results in cytotoxicity against breast cancer stem cells in vitro and xenografts in vivo through apoptosis and an incomplete autopaghy in breast cancer
Keywords: 7-AAD; 7-amino-actinomycin D; ABC; ATP-binding cassette; AEC; 3-amino-9-ethyl carbazole; ATD; acute toxicity determination; Atg5; autophagy protein 5; ATP; adenosine-5â²-triphosphate; BCL-2; B-cell lymphoma 2; Bip/GRP78; binding immunoglobulin protein/78
Inhibitory effects of (+)-spectaline and iso-6-spectaline from Senna spectabilis on the growth and ultrastructure of human-infective species Trypanosoma brucei rhodesiense bloodstream form
Keywords: Senna spectabilis; Piperidine alkaloids; (+)-spectaline; Iso-6-spectaline; Tyrpanosoma brucei rhodesiense; Autophagy; HAT; human African trypanosomiasis; DNDi; Drugs for Neglected Diseases initiative; IC50; half maximal inhibitory concentration; PCD; prog
Effects of different drying temperatures on the content of phenolic compounds and carotenoids in quinoa seeds (Chenopodium quinoa) from Finland
Keywords: DW; dry weight; EtOAc; ethyl acetate; RT; room temperature; T; temperature; US; ultrasonic; Chenopodium quinoa; Drying temperature; Pseudocereals; Phenolic compounds; Bound phenolic compounds; Carotenoids; Xanthophylls; Food analysis; Food composition;
Comprehensive review on flavonoids biological activities of Erythrina plant species
Keywords: 5-LOX; 5-lipoxygenase; AMPK; adenosine monophosphate-activated protein kinase; Bax; Bcl-2-associated X protein; BC; lymphoma cell line; Bcl-2; B-cell CLL/lymphoma 2; Caco2; human epithelial colorectal adenocarcinoma cells; CCRF-CEM; T lymphoblastoid cell
Inhibition of human monoamine oxidase A and B by flavonoids isolated from two Algerian medicinal plants
Keywords: Antidepressant; Bioassay-guided fractionation; HR-ESI-MS; Molecular docking; Monoamine oxidase; NMR; BuOH; n-Butanol; CC; Chromatographic column; CH2CL2; Dichloromethane; CHCl3; Chloroform; EtOAc; Ethyl acetate; EtOH; Ethanol; FAD; Flavin adenine dinucleo
Synthesis and evaluation of a novel urea-based 68Ga-complex for imaging PSMA binding in tumor
Keywords: SPECT; single photon emission computer tomography; PET; positron emission tomography; HPLC; High performance liquid chromatography; HRMS; High-resolution mass spectrometry; PBS; phosphate buffered saline; SPE; solid-phase extraction; GMP; good manufacturi
Hexane fraction of adlay (Coix lachryma-jobi L.) testa ethanolic extract inhibits human uterine sarcoma cancer cells growth and chemosensitizes human uterine sarcoma cells to doxorubicin
Keywords: Adlay testa; Doxorubicin; MES-SA; MES-SA/Dx5; HUtSMCs; Multidrug resistance; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; AHE; the ethanoic extracts of adlay hull; ABE; the ethanoic extracts of adlay bran; ATE; the ethanoic extracts
Functionalized liposomes and phytosomes loading Annona muricata L. aqueous extract: Potential nanoshuttles for brain-delivery of phenolic compounds
Keywords: Annona muricata L.; Phytosomes; Liposomes; mApoE; hMAO-A; Hydrogen peroxide scavenging; AE; aqueous extract; ApoE; apolipoprotein E; BBB; blood-brain barrier; CNS; central nervous system; DCM; dichloromethane; DMSO; dimethylsulfoxide; DSPE-PEG-maleimide;
Design, synthesis and biological screening of 2-aminobenzamides as selective HDAC3 inhibitors with promising anticancer effects
Keywords: B16F10; murine melanoma cells; CDCl3; deuterated chloroform; CTCL; cutaneous T-cell lymphoma; DCM; dichloromethane; DFT; density functional theory; DMAP; 4-Dimethylaminopyridine; DMEM; Dulbecco's modified Eagle's media; DMF; dimethylformamide; DMSO; dimet
Synthesis and biological evaluation of Santacruzamate-A based analogues
Keywords: AcCN; acetonitrile; BnOH; benzyl alcohol; DMF; N,N-dimethylformamide; DMSO; dimethylsulphoxide; EtOAc; ethyl acetate; EtOH; ethanol; GABA; γ-aminobutyric acid; GADPH; glyceraldehyde 3-phosphate dehydrogenase; HBTU; O-(benzotriazol-1-yl)-N,N,Nâ²,Nâ²-tet
Topical antiedematogenic and anti-inflammatory effect of Scutia buxifolia Reissek gel and stability study
Keywords: Scutia buxifolia; Coronilha; Edema; Inflammation; UVB irradiation; Croton oil; CE; Crude extract of Scutia buxifolia;; EtOAc; Ethyl acetate of Scutia buxifolia; HPLC; High-performance liquid chromatography; UVB; Ultraviolet radiation B; UV-irr; Ultraviole