Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; ALS; amyotrophic lateral sclerosis; BDNF; brain-derived neurotropic factor; CerS; ceramide synthase; CNS; central nervous system; CPL; cecal ligation and puncture; cPLA2; cytosolic phospholipase A2; CSA; cyclosporine A; CTL; cytotoxic T lymphocytes; CYP45
مقالات ISI پروتئین کیناز کنترل شده سیگنال غیر سلولی (ترجمه نشده)
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Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; ADAM; A Disintegrin And Metalloproteinase; ADAMTS; a disintegrin and metalloproteinase with thrombospondin motifs; Akt; RAC-alpha serine/threonine-protein kinase; AP1; transcription factor AP-1; BMP; bone morphogenetic protein; DNMT; DNA methyl-transferas
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; Neurodegeneration; Flavonoids; Antioxidant; Signalling pathways; Neuroinflammation; AD; Alzheimer's disease; PD; Parkinson's disease; HD; Huntington's disease; ALS; amyotrophic lateral sclerosis; MS; multiple sclerosis; DA; dopamine agonist; IFN; interfer
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; AMP; adenosine 5â²-monophosphate; ASIC; acid-sensitive ion channel; ATP; adenosine 5â²-triphosphate; CNS; central nervous system; CREB; cyclic AMP responsive element binding protein; DAG; diacylglycerol; ERK; extracellular signal-regulated protein kinas
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; 11β-HSD1; 11β-hydroxysteroid dehydrogenase type 1; BDNF; brain-derived neurotrophic factor; CCI; controlled cortical impact; CD11b; complement receptor 3; CORT; corticosterone; ERK; extracellular signal-regulated protein kinase; GC; glucocorticoid; GLT1
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; Akt; protein kinase B; DHA; docosahexaenoic acid; ERK; extracellular signal-regulated protein kinase; NAPE; N-acylphosphatidylethanolamine; PC; phosphatidylcholine; PDK1; phosphoinositide-dependent kinase-1; PE; phosphatidylethanolamine; PEMT; phosphatidy
Strategies of biochemical adaptation for hibernation in a South American marsupial Dromiciops gliroides: 1. Mitogen-activated protein kinases and the cell stress response
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; CREB; cAMP response element binding protein; ERK; extracellular signal-regulated protein kinase; JNK; c-Jun N-terminal kinase; MAPK; mitogen-activated protein kinase; MAPKK; MAPK kinase; MAPKKK; MAPKK kinase; p38; p38 protein kinase; TNF-α; tumor necrosi
Resveratrol inhibits proliferation, migration and invasion via Akt and ERK1/2 signaling pathways in renal cell carcinoma cells
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; RES; resveratrol; RCC; renal cell carcinoma; EMT; epithelial-mesenchymal transition; MMP; matrix metalloproteinase; ECM; extracellular matrix; ERK; extracellular signal-regulated protein kinase; MAPK; mitogen-activated protein kinases; DMEM; Dulbecco's
Different doses of sevoflurane facilitate and impair learning and memory function through activation of the ERK pathway and synthesis of ARC protein in the rat hippocampus
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; Sevoflurane; Learning and memory; Extracellular signal-regulated protein kinase; ARC; Hippocampus;
Artemisia asiatica ethanol extract exhibits anti-photoaging activity
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; Aa-EE; Artemisia asiatica Nakai ethanol extract; UVB; ultraviolet-B; NO; nitric oxide; PGE2; prostaglandin E2; RT-PCR; reverse transcriptase polymerase chain reaction; MMPs; matrix metalloproteinases; COX-2; cyclooxygenase-2; TGM-1; transglutamase-1; HAS;
Triptolide up-regulates metabotropic glutamate receptor 5 to inhibit microglia activation in the lipopolysaccharide-induced model of Parkinson's disease
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; mGlu; Metabotropic glutamate receptor; PD; Parkinson's disease; T10; Triptolide; LPS; lipopolysaccharide; NO; nitric oxide; iNOS; inducible nitric oxide synthase; TNF; tumor necrosis factor; IL; interleukin; SN; substantia nigra; COX; cyclooxygenase; JN
Memantine ameliorates depressive-like behaviors by regulating hippocampal cell proliferation and neuroprotection in olfactory bulbectomized mice
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; Apoptosis; Cell proliferation; Depression; Emotional behavior; Olfactory bulbectomy; Neuroinflammation; ANOVA; analysis of variance; Bax; Bcl-2-associated protein X; Bcl-2; B cell lymphoma/leukemia gene 2; BDNF; brain-derived neurotrophic factor; BrdU; 5-
Aerobic exercise in adolescence results in an increase of neuronal and non-neuronal cells and in mTOR overexpression in the cerebral cortex of rats
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; Akt; protein kinase B; CREB; cAMP response element-binding protein; DAPI; 4â²-6-diamidino-2-phenylindole dihydrochloride; ERK; extracellular signal-regulated protein kinase; mTOR; mammalian target of rapamycin; p70S6K; p70 ribosomal protein S6 kinase; ph
S-nitrosylation of the IGF-1 receptor disrupts the cell proliferative action of IGF-1
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; Insulin-like growth factor; Nitric oxide; S-Nitrosylation; Signal transduction; ERK; extracellular signal-regulated protein kinase; IGF-1; insulin-like growth factor-1; IGF-1R; insulin-like growth factor-1 receptor; IRS; insulin receptor substrate; MAPK;
The role of miR-190a in methylglyoxal-induced insulin resistance in endothelial cells
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; AG; aminoguanidine; AGE; advanced glycation end-product; Akt; protein kinase B; eNOS; endothelial NO synthase; ERK; extracellular signal-regulated protein kinase; Glo1; glyoxalase 1; HDAC; histone deacetylase; HUVECs; human umbilical vein endothelial cell
AKT-dependent phosphorylation of the SAM domain induces oligomerization and activation of the scaffold protein CNK1
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; ARF; ADP ribosylation factor; CNK; connector enhancer of KSR; ERK; extracellular signal-regulated protein kinase; EGF; epidermal growth factor; GF; growth factor; IGF; insulin-like growth factor; MAPK; mitogen-activated protein kinase; MEK; MAPK/ERK kinas
TRAF1 Is Critical for DMBA/Solar UVR-Induced Skin Carcinogenesis
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; AK; actinic keratosis; DMBA; 7,12-dimethylbenz[a]anthracene; ERK; extracellular signal-regulated protein kinase; HA; hemagglutinin; HEKa; adult human epidermal keratinocyte; HEK; human embryonic kidney; K; keratin; MAPK; mitogen-activated protein kinase;
Optogenetics - Bringing light into the darkness of mammalian signal transduction
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; AsLOV2; Avena sativa light-oxygen-voltage domain 2; ChR2; Channelrhodopsin-2; CIB1; Chryptochrome-interacting basic helix-loop-helix 1; CIBN; N-terminus of CIB1; COP1; Constitutive photomorphogenesis protein 1; CPH1; Cyanobacterial phytochrome 1; CRY2; Cr
MC1R signaling. Intracellular partners and pathophysiological implications
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; AC; adenylyl cyclase; ACTH; adrenocorticotropic hormone; ARRB; β-arrestin; ASIP; agouti signal protein; CBD103; dog β-defensin-3; CREB; cAMP responsive-element binding protein; EDN1; endothelin 1; ER; endoplasmic reticulum; ERK; extracellular signal-reg
Inflammatory MAPK and NF-κB signaling pathways differentiated hepatitis potential of two agglomerated titanium dioxide particles
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; TiO2NPs; titanium dioxide nanoparticles; NF-κB; nuclear factor kappa enhancer binding protein; IκBα; inhibitory protein of NF-κB; MAPK; mitogen-activated protein kinase; ERK; extracellular signal-regulated protein kinase; p38; p38-MAPK; JNK; c-Jun N-t
Vitexin reduces neutrophil migration to inflammatory focus by down-regulating pro-inflammatory mediators via inhibition of p38, ERK1/2 and JNK pathway
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; Cytotoxicity; Flavonoid; Leukocyte recruitment; Immunomodulation; ZY; zymosan; CG; carrageenan; fMLP; N-formyl-methionyl-leucyl-phenylalanine; LPS; lipopolysaccharide; IL; interleukin; TNF-α; tumor necrosis factor α; NF-kB; nuclear factor-kB; MAPKs; mit
α-MSH modulates cell adhesion and inflammatory responses of synovial fibroblasts from osteoarthritis patients
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; ACTH; adrenocorticotropin; ASIP; Agouti signalling protein; ATP; adenosine triphosphate; BSA; bovine serum albumin; cAMP; 3â²,5â²-cyclic adenosine monophosphate; ELISA; enzyme-linked immunosorbent assay; ERK; extracellular signal-regulated protein kinas
Modulatory influences of estradiol and other anorexigenic hormones on metabotropic, Gi/o-coupled receptor function in the hypothalamic control of energy homeostasis
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; 2-AG; 2-arachidonoylglycerol; AgRP; agouti-related peptide; AMPK; AMP-activated protein kinase; ARC; hypothalamic arcuate nucleus; CRH; corticotropin-releasing hormone; DSI; depolarization-induced suppression of inhibition; ERK; extracellular signal-regul
Anti-tumor activity of sorafenib in a model of a pediatric hepatocellular carcinoma
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; pHCC; pediatric hepatocellular carcinoma; aHCC; adult hepatocellular carcinoma; ERK; extracellular signal-regulated protein kinase; HB; hepatoblastoma; HC-AFW1; Pediatric hepatocellular carcinoma; pHCC; Xenograft; Sorafenib; β-catenin;
6-O-Veratroyl catalpol suppresses pro-inflammatory cytokines via regulation of extracellular signal-regulated kinase and nuclear factor-κB in human monocytic cells
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; Anti-inflammation; Pro-inflammatory cytokines; 6-O-Veratroyl catalpol; THP-1 cells; PMA; 6-O; 6-O-veratroyl catalpol; IL-1; Interleukin-1; ERK; Extracellular signal-regulated protein kinase; NF-κB; Nuclear Factor-κB; PMA; phorbol12-myristate-13-acetate;
Let-7g induces granulosa cell apoptosis by targeting MAP3K1 in the porcine ovary
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; Let-7g; MAP3K1; FoxO1; Granulosa cell; Apoptosis; miRNAs; mircoRNAs; 3â² UTR; 3â²-untranslated regions; GCs; granulosa cells; PTEN; phosphatase and tensin homolog; PBS; phosphate buffered saline; PI; propidium iodide; BSA; bovine serum albumin; DAPI; AT
Splicing inhibition induces gene expression through canonical NF-κB pathway and extracellular signal-related kinase activation
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; Spliceostatin A; Extracellular signal-regulated protein kinase; NF-κB;
Cycloastragenol, a triterpene aglycone derived from Radix astragali, suppresses the accumulation of cytoplasmic lipid droplet in 3T3-L1 adipocytes
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; RA; Radix astragali; CAG; cycloastragenol; AG-IV; astragaloside IV; ERK; extracellular signal-regulated protein kinase; PFA; paraformaldehyde; Lova; Lovastatin; GSH; reduced glutathione level; ROS; reactive oxygen species; MMP; mitochondrial membrane pote
Kidney cancer cells secrete IL-8 to activate Akt and promote migration of mesenchymal stem cells
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; Kidney cancer; Mesenchymal stem cell; Interleukin-8; Extracellular signal-regulated protein kinase; Akt;
Halofuginone improves muscle-cell survival in muscular dystrophies
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; CMD; congenital MD; DMD; Duchenne MD; ECM; extracellular matrix; ERK; extracellular signal-regulated protein kinase; DAPI; 4â²,6-diamidino-2-phenylindole; MAPK; mitogen-activated protein kinase; MDs; muscular dystrophies; PI3K; phosphoinositide 3 kinase;
Nrf2/ARE pathway activation, HO-1 and NQO1 induction by polychlorinated biphenyl quinone is associated with reactive oxygen species and PI3K/AKT signaling
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; ARE; antioxidant response element; Cul3; Cullin 3; DAPI; 4â²,6-diamidino-2-phenylindole; EMSA; electrophoretic mobility shift assay; EpRE; electrophile-responsive element; ERK; extracellular signal-regulated protein kinase; GSH; glutathione; GSK-3β; gly
New insights into Notch1 regulation of the PI3K-AKT-mTOR1 signaling axis: Targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; ADAM; a disintegrin and metalloprotease; AICAR; 5-aminoimidazole-4-carboxamide ribonucleotide; AKT; protein kinase B (PKB); ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; AMPK; adenosine monophosphate (AMP) activated protein kinase; ANK;
Monosaccharide digitoxin derivative sensitize human non-small cell lung cancer cells to anoikis through Mcl-1 proteasomal degradation
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; Bcl-2; B-cell lymphoma 2; Casp-3; caspase-3; CHX; cycloheximide; CG; cardiac glycoside; DMSO; dimethyl sulfoxide; D6-MA; α-l-rhamnose monosaccharide derivative; ECM; extracellular matrix; ERK; extracellular signal-regulated protein kinase; FAK; focal adh
Effects of activated fibroblasts on phenotype modulation, EGFR signalling and cell cycle regulation in OSCC cells
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; Akt; protein kinase B; CAF; cancer associated fibroblast; EGFR; epidermal growth factor receptor; EMT; epithelial mesenchymal transition; ERK; extracellular signal-regulated protein kinase; FCM; fibroblast conditioned medium; HNSCC; head and neck squamous
Zinc chloride exposure increases heme oxygenase-1 expression in MDPC-23 odontoblast-like cells
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; Akt; amino kinase terminal; DMSO; dimethyl sulfoxide; ERK; extracellular signal-regulated protein kinase; HO-1; heme oxygenase-1; JNK; c-Jun NH2-terminal kinase; MAPKs; mitogen-activated protein kinases; MK-2; MAPK-activated protein kinase-2; NF-κB; nucl
Selaginella tamariscina (Beauv.) possesses antimetastatic effects on human osteosarcoma cells by decreasing MMP-2 and MMP-9 secretions via p38 and Akt signaling pathways
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; Metastasis; Selaginella tamariscina; Osteosarcoma; MMP-2; MMP-9; ECM; extracellular matrix; ERK; extracellular signal-regulated protein kinase; JNK; c-Jun N-terminal kinase; MAPK; mitogen-activated protein kinase; MMP; matrix metalloproteinase; PI3K; phos
Neuroprotective effect of Pycnogenol® following traumatic brain injury
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; Akt; protein kinase B; CAT; catalase; CON; contralateral; JNK; c-Jun NH(2)-terminal kinase; ERK; extracellular signal-regulated protein kinase; G-6-PD; glucose-6-phosphate; GPx; glutathione peroxidase; GR; glutathione reductase; GSH; glutathione; GSK; gly
TCDD induces the expression of insulin-like growth factor binding protein 4 in 5L rat hepatoma cells: A cautionary tale of the use of this cell line in studies on dioxin toxicity
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; AhR; aryl hydrocarbon receptor; AKT1S1; proline-rich AKT1 substrate 1; CYP1A1; cytochrome P450 1A1; 4E-BP1; eukaryotic translation initiation factor 4E-binding protein 1; ERK; extracellular signal-regulated protein kinase; GSK3; glycogen synthase kinase 3
Intrathecal endothelin-1 has antinociceptive effects in rat model of postoperative pain
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; Dorsal root ganglion neuron; Endothelin-1; Extracellular signal-regulated protein kinase; Microglia; Postoperative pain;
Potent synergistic effect of IL-3 and TNF on matrix metalloproteinase 9 generation by human eosinophils
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; Ab; antibody; βc; common beta chain; Ct; comparative cycle threshold; ECM; extracellular matrix; ERK; extracellular signal-regulated protein kinase; GUS; glucuronidase; MAP; mitogen-activated protein kinase; MEK; mitogen-activated protein kinase kinase;
Mechanisms of human smooth muscle cell proliferation and transplant vasculopathy induced by HLA class I antibodies: In vitro and in vivo studies
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; TV; transplant vasculopathy; HLA; human leukocyte antigen; SMC; smooth muscle cells; EC; endothelial cells; MMP; matrix metalloproteinases; MMP-2; matrix metalloproteinase 2; FAK; focal adhesion kinase; mTOR; mammalian target of rapamycin; PI3K; phosphati
Protein phosphorylation involved in the gene expression of the hydrogen sulphide producing enzyme cystathionine γ-lyase in the pancreatic β-cell
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; CaMK; Ca2+/calmodulin-dependent protein kinase; CAT; cysteine aminotransferase; CBS; cystathionine β-synthase; CO; carbon monoxide; CSE; cystathionine γ-lyase; Elk1; Ets-like protein-1; ER; endoplasmic reticulum; ERK; extracellular signal-regulated prot
Constitutive expression of an antioxidant enzyme, glutathione S-transferase P1, during differentiation of human intestinal Caco-2 cells
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; DMSO; Dimethyl sulfoxide; ECL; Enhanced chemiluminescence; EDTA; Ethylenediaminetetraacetic acid; EGTA; Ethyleneglycol bis(2-aminoethyl ether)tetraacetic acid; ERK; Extracellular signal-regulated protein kinase; GST; Glutathione S-transferase; MAPK; Mitog
P38 MAPK is involved in enhanced NMDA receptor-dependent excitotoxicity in YAC transgenic mouse model of Huntington disease
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; aCSF; artificial cerebrospinal fluid; co-IP; co-immunoprecipitation; DIV; days in vitro; ERK; extracellular signal-regulated protein kinase; Ex-NMDARs; extrasynaptic NMDARs; GFP; green fluorescent protein; HD; Huntington disease; HIV-1; human immunodefici
Cisplatin induces platelet apoptosis through the ERK signaling pathway
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; Cisplatin; cis-diamminedichloroplatinum II; MEK; mitogen-activated protein kinase kinase; ERK; extracellular signal-regulated protein kinase; JNK; c-Jun N-terminal kinase; VWF; von Willebrand factor; DMSO; dimethyl sulfoxide; PMSF; phenylmethylsulfonyl fl
Selective interactions of spinophilin with the C-terminal domains of the δ- and μ-opioid receptors and G proteins differentially modulate opioid receptor signaling
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; GPCR; G protein-coupled receptors; RGS; Regulators of G protein Signaling; ÎÎRGS4; RGS4 lacking its N-terminal domain; 6xHis; hexahistidine; aa; amino acids; GEFs; Guanine nucleotide exchange factors; AC; adenylyl cyclase; DAMGO; [D-Ala2,N-MePhe4,Gly5-o
Norcantharidin induces cell cycle arrest and inhibits progression of human leukemic Jurkat T cells through mitogen-activated protein kinase-mediated regulation of interleukin-2 production
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; AP-1; activating protein-1; CaN; calcineurin; CsA; Cyclosporine A; CyP; cyclophilin; ERK; extracellular signal-regulated protein kinase; FCS; fetal calf serum; FK506; Tacrolimus; IP3; inositol triphosphate; JNK; c-Jun NH2-terminal kinases; MAPK; mitogen-a
CommentaryUnderstanding SOS (Son of Sevenless)
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; AhR; aryl hydrocarbon receptor; Cdc 25; cell division cycle 25; CFC; cardio-facio-cutaneous syndrome; DH; Dbl homology; E3b1; Eps8 SH3 domain binding protein 1; Eps8; EGFR pathway substrate 8; ERK; extracellular signal-regulated protein kinase; Grb2; grow
(−)-Epigallocatechin-3-gallate induces up-regulation of Th1 and Th2 cytokine genes in Jurkat T cells
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; (−)-Epigallocatechin-3-gallate; Hydrogen peroxide; Interleukin 2; Interferon γ; Interleukin 5; Interleukin 13; Extracellular signal-regulated protein kinase; c-jun NH2-terminal kinase; Jurkat
Differential regulation of human tyrosine hydroxylase isoforms 1 and 2 in situ: Isoform 2 is not phosphorylated at Ser35
Keywords: پروتئین کیناز کنترل شده سیگنال غیر سلولی; TH; tyrosine hydroxylase; Ser; serine; hTH; human TH; BH4; tetrahydrobiopterin; ERK; extracellular signal-regulated protein kinase; CaMKII; calcium/calmodulin-dependent protein kinase II; DMEM; Dulbecco's Modified Eagle Medium; Tyrosine hydroxylase; Human