دانلود مقالات ISI درباره Fak + ترجمه فارسی

Cullin 5-RING E3 ubiquitin ligases, new therapeutic targets?

Keywords: E3 ubiquitin ligase; Cullin RING ligase; Ubiquitin-proteasome system; Therapeutic targets; ASB; ankyrin repeat-containing proteins with a SOCS box; β-Trcp; β-transducin repeat-containing protein; BTB; bric-a-brac; CIS1; cytokine-inducible Src homology

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Fyn kinase genetic ablation causes structural abnormalities in mature retina and defective Müller cell function

Keywords: Fyn kinase; Retina; Müller glia; FAK; Akt kinase; Optokinetic response

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

An early dysregulation of FAK and MEK/ERK signaling pathways precedes the β-amyloid deposition in the olfactory bulb of APP/PS1 mouse model of Alzheimer's disease

Keywords: AD; Alzheimer's disease; APP; amyloid precursor protein; BAD; Bcl2-associated agonist of cell death; Camk2a; Ca2 +/CaM-dependent protein kinase type II subunit alpha; ERK; extracellular signal-regulated kinase; FAK; focal adhesion kinase; Gdap1; ganglios

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Imipramine administration induces changes in the phosphorylation of FAK and PYK2 and modulates signaling pathways related to their activity

Keywords: α1-AR; α1-adrenergic receptor; CaMKII; Ca2 +/calmodulin-dependent protein kinase II; DAG; diacylglycerol; ECM; extracellular matrix; ERK1/2; extracellular signal-regulated kinases 1 and 2; FAK; focal adhesion kinase; GPCR; G-protein coupled receptor; L

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

14-3-3η is a novel growth-promoting and angiogenic factor in hepatocellular carcinoma

Keywords: Cxcl1; C-X-C motif-ligand 1; ECs; endothelial cells; EMT; epithelial to mesenchymal transition; ERK; extracellular signal-regulated kinase; FAK; focal adhesion kinase; FRA-1; fos related antigen 1; NK-κB; nuclear factor kappa B; PCNA; proliferating cell

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

ECM Signaling Regulates Collective Cellular Dynamics to Control Pancreas Branching Morphogenesis

Keywords: pancreas; morphogenesis; branching; progenitor; integrin; time-lapse imaging; adhesion; E-cadherin; Src; FAK; extracellular matrix

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibition of growth, migration and invasion of human bladder cancer cells by antrocin, a sesquiterpene lactone isolated from Antrodia cinnamomea, and its molecular mechanisms

Keywords: Bladder cancer; Antrocin; Invasion; FAK; EMT

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Retinoic acid induces nuclear FAK translocation and reduces breast cancer cell adhesion through Moesin, FAK, and Paxillin

Keywords: Retinoic acid; Moesin; FAK; Paxillin; Cell adhesion/migration; Breast cancer cells

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Identification of novel FAK and S6K1 dual inhibitors from natural compounds via ADMET screening and molecular docking

Keywords: Virtual screening; FAK; S6K1; ADMET; Molecular docking

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Symmetry breaking in spreading RAT2 fibroblasts requires the MAPK/ERK pathway scaffold RACK1 that integrates FAK, p190A-RhoGAP and ERK2 signaling

Keywords: ERK, extracellular signal-regulated kinase; p190, p190A-RhoGAP; RACK1, receptor for activated C kinase 1; FAK, focal adhesion kinaseRACK1; ERK; FAK; p190A-RhoGAP; Polarity; Feed-forward loop

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Aryl hydrocarbon receptor-dependent up-regulation of the heterodimeric amino acid transporter LAT1 (SLC7A5)/CD98hc (SLC3A2) by diesel exhaust particle extract in human bronchial epithelial cells

Keywords: AhR; aryl hydrocarbon receptor; BCH; 2-aminobicyclo-(2,2,1)-heptane-2-carboxylic acid; CYP; cytochrome P-450; DEP; diesel exhaust particle; DEPe; diesel exhaust particle extract; DMSO; dimethyl sulfoxide; EGR1; early growth response 1; ERK; extracellular

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Integrins and integrin-related proteins in cardiac fibrosis

Keywords: α-SMA; α-smooth muscle actin; Ang II; angiotensin II; CFs; cardiac fibroblasts; CM; cardiac myocyte; ED-A FN; ED-A fibronectin; EC; endothelial cells; EndMT; endothelial-mesenchymal transition; EMT; epithelial-mesenchymal transition; ECM; extracellu

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Bile acids-mediated overexpression of MUC4 via FAK-dependent c-Jun activation in pancreatic cancer

Keywords: Bile acids; Pancreatic cancer; MUC4; FAK; FXR; c-Jun; PC; pancreatic cancer; PDAC; pancreatic ductal adenocarcinoma; BA; bile acids; DCA; deoxycholic acid; CDCA; chenodeoxycholic acid; FXR; farnesoid-x-receptor; FAK; focal adhesion kinase; MAPK; mitogen a

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Ganglioside GM2 mediates migration of tumor cells by interacting with integrin and modulating the downstream signaling pathway

Keywords: GSL; Glycosphingolipid; MAPK; Mitogen activated protein kinase; FAK; Focal adhesion kinase; RCC; Renal cell carcinoma; GBM; Glioblastoma multiforme; DRGs; Differentially regulated genes; GO; Gene ontology; BiNGO; Biological network gene ontology; RMA; Rob

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2016 سفارش ترجمه

IGF-I/EGF and E2 signaling crosstalk through IGF-IR conduit point affects breast cancer cell adhesion

Keywords: IGF-I; insulin like growth factor-I; EGF; epidermal growth factor; E2; Estradiol; ERα; estrogen receptor α; Erk1/2; extracellular signal-regulated kinases; FAK; Focal Adhesion Kinase; Breast cancer; Adhesion; IGF-IR; IGF-I; EGF; E2;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2016 سفارش ترجمه

HMGB1 induces human non-small cell lung cancer cell motility by activating integrin αvβ3/FAK through TLR4/NF-κB signaling pathway

Keywords: HMGB1; NSCLC; Migration; TLR4; αvβ3; FAK;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2016 سفارش ترجمه

Low density lipoprotein receptor-related protein 1 mediated endocytosis of β1-integrin influences cell adhesion and cell migration

Keywords: LRP1; low density lipoprotein receptor related-protein 1; Snx17; Sorting nexin 17; PSD95; postsynaptic density protein 95; Dab-2; disabled homolog 2; ECM; extracellular matrix; RMS; rostral migratory stream; BrdU; 5-bromo-2-deoxyuridine; CPZ; chlorpromazi

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

The store-operated Ca2 + entry-mediated signaling is important for cancer spread

Keywords: bFGF; basic fibroblast growth factor; CRAC; calcium release-activated channels; CAD; CRAC activation domain;; CaM kinase II; Ca2 +/calmodulin-dependent protein kinase II; ER; endoplasmic reticulum; EGF; epidermal growth factor; ECM; extracellular matrix;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2016 سفارش ترجمه

The p21-activated kinase, PAK2, is important in the activation of numerous pancreatic acinar cell signaling cascades and in the onset of early pancreatitis events

Keywords: CCK; COOH-terminal octapeptide of cholecystokinin; TPA; 12-O-tetradecanoylphorbol-13-acetate; PAK; p21-activated kinases; SFK; Src family of kinases; PKC; protein kinase C; PYK2; proline-rich tyrosine kinase 2; FAK; focal adhesion kinase; SHC; Src homolog

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2016 سفارش ترجمه

Identification of EDIL3 on extracellular vesicles involved in breast cancer cell invasion

Keywords: EVs; Extracellular vesicles; FAK; Focal adhesion kinase; MVB; Multivesicular bodies; cirEVs; Circulating extracellular vesicles; EGF; Epidermal growth factor; TEM; Transmission electron microscope; NTA; Nanoparticle tracking analysis; TEABC; Triethylammon

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2016 سفارش ترجمه

Versican and its associated molecules: Potential diagnostic markers for multiple myeloma

Keywords: Multiple myeloma; Versican; β-Catenin; β1 Integrin; FAK; Diagnostic marker;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

The involvement of FAK-PI3K-AKT-Rac1 pathway in porcine reproductive and respiratory syndrome virus entry

Keywords: Porcine reproductive and respiratory syndrome virus; Infection; FAK; Rac1;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Diverse roles of LPA signaling in the intestinal epithelium

Keywords: LPA; lysophosphatidic acid; IEC; intestinal epithelial cell; IBD; inflammatory bowel disease; CRC; colorectal cancer; PA; phosphatidic acid; PLA; phospholipase A; ATX; autotaxin; YAMC; young adult mouse colonic epithelium; MSIE; mouse small intestinal epi

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Tivantinib (ARQ-197) exhibits anti-tumor activity with down-regulation of FAK in oral squamous cell carcinoma

Keywords: Oral squamous cell carcinoma (OSCC); Tivantinib; Apoptosis; FAK;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Could caveolae be acting as warnings of mitochondrial ageing?

Keywords: ERK; extracellular signal-regulated kinases; FAK; focal adhesion kinase; Nrf2; nuclear erythroid 2 p45-related factor-2; Shp-2; SH2 domain-containing phosphatase-2; CSK; c-Src tyrosine kinase; HO-1; hemeoxigenase 1; HIF1; hypoxia induced factor 1; SHP-2;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

p70S6K is regulated by focal adhesion kinase and is required for Src-selective autophagy

Keywords: FAK; PDK1; Akt; p70S6K; S6; Autophagosomes;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Indigo naturalis and its component tryptanthrin exert anti-angiogenic effect by arresting cell cycle and inhibiting Akt and FAK signaling in human vascular endothelial cells

Keywords: Tryptanthrin; Psoriasis; Angiogenesis; Cell cycle arrest; Akt; FAK;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Krüppel-like transcription factor 8 (Klf8) is expressed and active in the neurons of the mouse brain

Keywords: FAK; Focal Adhesion Kinase; KLF; Krüppel-like factor; NLS; nuclear localization signal; ZF; zinc finger; Krüppel-like factor 8; Transcription factor; Mouse brain; Neurons;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

The anti-tumour activity of rLj-RGD4, an RGD toxin protein from Lampetra japonica, on human laryngeal squamous carcinoma Hep-2 cells in nude mice

Keywords: rLj-RGD4; Laryngeal squamous carcinoma; Anti-tumour; Hep-2; Nude mice; RGD; Arg-Gly-Asp; rLj-RGD4; recombinant Lampetra japonica (Arg-Gly-Asp) 4; TUNEL; terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labelling; MVD; intratumoural micr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Lewis y enhances CAM-DR in ovarian cancer cells by activating the FAK signaling pathway and upregulating Bcl-2/Bcl-XL expression

Keywords: Lewis y; CAM-DR; Integrin α5β1; FAK signaling pathway; Bcl-2; ECM; extracellular matrix; CAM-DR; cell adhesion-mediated drug resistance; FN; fibronectin; FAK; focal adhesion kinase; PI3K; phosphatidyl inositol 3-kinase; Akt; protein kinase B; ERK; extra

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

MicroRNAs in osteosarcoma

Keywords: OS; osteosarcoma; miRNAs; microRNAs; CSCs; cancer stem cells; RNA pol; RNA polymerase; DGCR8; DiGeorge syndrome critical gene 8; RISC; RNA-induced silencing complex; Exp 5; exportin 5; Ago; argonaute; MREs; miRNA recognition elements; APE1; apurinic/apyri

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

PTPN21 exerts pro-neuronal survival and neuritic elongation via ErbB4/NRG3 signaling

Keywords: NRG3; Neuregulin 3; eQTL; expression quantitative trait locus; SNPs; single nucleotide polymorphisms; PTPN21; protein tyrosine phosphatase non-receptor 21; GWAS; genome-wide association study; RTK; receptor tyrosine kinase; FAK; focal adhesion kinase; KIF

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Non-coding RNA repertoires in malignant pleural mesothelioma

Keywords: AD; adenocarcinoma; ADARB2; RNA-specific adenosine deaminase, B2; aCGH; array comparative genomic hybridization; BAPE; benign asbestos-related pleural effusion; CCND1; cyclin D1; ceRNA; competing endogenous RNA; CREB; cAMP response element binding protein

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

MicroRNA-7: A miRNA with expanding roles in development and disease

Keywords: ACK1; activated CDC42 kinase 1; BASP1; brain abundant, membrane attached signal protein 1; c-Myc; v-Myc avian myelocytomatosis viral oncogene homolog; CD57; cluster of differentiation 57; CD44; cluster of differentiation 44; ciRS-7; circular RNA sponge fo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Src controls neuronal migration by regulating the activity of FAK and cofilin

Keywords: BSA; bovine serum albumin; CP; cortical plate; DCP; deeper region of cortical plate; EDTA; ethylenediaminetetraacetic acid; EGFP; enhanced green fluorescent protein; FAK; focal adhesion kinase; IZ; intermediate zone; PBS; phosphate-buffered saline; PFA; p

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Research ReportSerine protease inhibitor (SERPIN) B1 suppresses cell migration and invasion in glioma cells

Keywords: SERPINB1; serpin peptidase inhibitor, clade B, member 1; MMP; matrix metalloproteinase; FAK; focal adhesion kinase; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; MAPK; mitogen-activated protein kinase; PI3K; phosphoinositide 3-kinase; SERPINB1; MMP-2;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Anti-angiogenic activities of snake venom CRISP isolated from Echis carinatus sochureki

Keywords: ES-CRISP; Echis carinatus sochureki cysteine-rich secretory protein; CMFDA; 5-chloromethylfluororescein diacetate; CAM; chorioallantoic membrane; EC; endothelial cell; gHMVEC; glioma human microvascular endothelial cells; HUVEC; human umbilical cord endot

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Embryonal Fyn-associated substrate (EFS) and CASS4: The lesser-known CAS protein family members

Keywords: 5-HT; 5-hydroxytryptamine, serotonin; A549; non-small cell lung cancer cell line; AD; Alzheimer's disease; ADPKD; autosomal dominant polycystic kidney disease; Aire; autoimmune regulator; AP-1; activator protein 1; APP; amyloid precursor protein; AREB6; Z

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

HPW-RX40 restores anoikis sensitivity of human breast cancer cells by inhibiting integrin/FAK signaling

Keywords: Anoikis; β-Nitrostyrene; Integrin; FAK; Metastasis; Breast cancer

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Focal adhesion kinase and p53 synergistically decrease neuroblastoma cell survival

Keywords: FAK; p53; SH-EP; WAC(2); Neuroblastoma

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Cell type-specific differences in β-glucan recognition and signalling in porcine innate immune cells

Keywords: CR3; complement receptor 3; ROS; reactive oxygen species; FAK; focal adhesion kinase; Syk; spleen tyrosine kinase; MAMPs; microorganism-associated molecular patterns; DCs; dendritic cells; LAL; limulus amebocyte lysate; mAbs; monoclonal antibodies; MDM; m

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Actin cytoskeleton organization, cell surface modification and invasion rate of 5 glioblastoma cell lines differing in PTEN and p53 status

Keywords: CGM; complete growth medium; ECM; extracellular matrix; Erk; extracellular signal regulated kinase; FAK; focal adhesion kinase; FBS; fetal bovine serum; GBM; Glioblastoma multiforme; MEK; MAPK/Erk kinase; MMP; matrix metalloproteinase; PTEN; phosphatase a

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Plasma membrane gp96 enhances invasion and metastatic potential of liver cancer via regulation of uPAR

Keywords: mgp96; uPAR; Liver cancer; MAPK; DFS; ADAMTS9; a disintegrin-like and metalloprotease domain with thrombospondin type 1 motifs 9; AIMP1; aminoacyl tRNA synthetase complex-interacting multifunctional protein 1; AKT; v-akt murine thymoma viral oncogene homo

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Gastrointestinal hormones/neurotransmitters and growth factors can activate P21 activated kinase 2 in pancreatic acinar cells by novel mechanisms

Keywords: CCK; COOH-terminal octapeptide of cholecystokinin; TPA; 12-O-tetradecanoylphorbol-13-acetate; PAKs; p21-activated kinases; SFK; Src family of kinases; PKC; protein kinase C; PYK2; proline-rich tyrosine kinase 2; FAK; focal adhesion kinase; PKD; protein ki

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

OGD induced modification of FAK- and PYK2-coupled pathways in organotypic hippocampal slice cultures

Keywords: OGD; FAK; PYK2; Src; Akt; MAPK

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

ARF1 regulates adhesion of MDA-MB-231 invasive breast cancer cells through formation of focal adhesions

Keywords: ARF; ADP-ribosylation factor; DMEM; Dulbecco's Modified Eagle Medium; DMSO; dimethyl sulfoxide; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; FAK; focal adhesion kinase; GAP; GTP activating protein; HCC70; Human Breast Cancer Cell

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

The vascular disrupting activity of OXi8006 in endothelial cells and its phosphate prodrug OXi8007 in breast tumor xenografts

Keywords: ANOVA; analysis of variance; BLI; bioluminescence imaging; CA4; combretastatin A-4; CA4P; combretastatin A-4 phosphate; DAPI; 4′,6-diamidino-2-phenylindole; DMSO; dimethyl sulfoxide; DTT; dithiothreitol; FAK; focal adhesion kinase; FDA; Federal Drug Adm

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Spondin 1 promotes metastatic progression through Fak and Src dependent pathway in human osteosarcoma

Keywords: Spondin 1; Fak; Src; Osteosarcoma;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Bioactivity-integrated UPLC/Q-TOF-MS of Danhong injection to identify NF-κB inhibitors and anti-inflammatory targets based on endothelial cell culture and network pharmacology

Keywords: Akt; protein kinase B; ANAVO; analysis of variance; Bax; Bcl-2 associated X protein; Bcl-2; B-cell lymphoma-2; BCR; B cells receptors; CA; caffeic acid; CAD; coronary artery disease; CHM; Chinese herbal medicines; DEX; dexamethasone; DHI; Danhong injectio

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

NOX4-dependent Hydrogen peroxide promotes shear stress-induced SHP2 sulfenylation and eNOS activation

Keywords: 2-OH-E+; 2-hydroxyethidium; BAEC; bovine aortic endothelial cell; BSA; bovine serum albumin; cGMP; cyclic guanosine monophosphate; cSrc; proto-oncogene tyrosine protein kinase Src; DHE; dihydroethidine; EDHF; endothelial-derived hyperpolarizing factor; eN

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2015 سفارش ترجمه