دانلود مقالات ISI درباره Fak + ترجمه فارسی

Vinculin negatively regulates transcription of MT1-MMP through MEK/ERK pathway

Keywords: DMEM; Dulbecco's modified Eagle's medium; ECM; extracellular matrix; ERK; extracellular signal-regulated kinase; FAK; focal adhesion kinase; MT1-MMP; membrane-type 1 matrix metalloproteinase; PBS; phosphate-buffered saline; PTEN; phosphatase and tensi

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

microRNA-7: A tumor suppressor miRNA with therapeutic potential

Keywords: ACK1; activated CDC42 kinase 1; Akt; V-Akt murine thymoma viral oncogene homolog; BCL-2; B-cell CLL/lymphoma 2; CCNE1; cyclin E1; ciRS-7; circular RNA sponge 7; c-Myc; V-Myc avian myelocytomatosis viral oncogene homolog; EGFR; epidermal growth factor rece

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Plasminogen activator inhibitor-1 regulates infiltration of macrophages into melanoma via phosphorylation of FAK-Tyr925

Keywords: Macrophage; PAI-1; FAK; Melanoma; Invasion; LRP1;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Association of CD98, integrin β1, integrin β3 and Fak with the progression and liver metastases of colorectal cancer

Keywords: Colorectal cancer; Liver metastasis; Integrin; Fak; CD98;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Regulation of cell-matrix adhesion by OLA1, the Obg-like ATPase 1

Keywords: OLA1; Obg-like ATPase 1; FAs; focal adhesions; FAK; focal adhesion kinase; ECM; extracellular matrix; ROCK; Rho-associated kinase; F-actin; filamentous actin; LIMKs; Lim family kinases; TESK; testicular protein kinases; pFAK(Y397); Tyr 397 phosphorylated

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Suppression of alpha-tocopherol ether-linked acetic acid in VEGF-induced angiogenesis and the possible mechanisms in human umbilical vein endothelial cells

Keywords: EC; endothelial cell; ECGS; endothelial cell growth supplement; ELISA; enzyme-linked immunosorbent assay; FAK; focal adhesion kinase; FBS; fetal bovine serum; HUVECs; human umbilical vein endothelial cells; MMPs; matrix metalloproteinases; VEGF; vascular

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

A monoterpene, unique component of thyme honeys, induces apoptosis in prostate cancer cells via inhibition of NF-κB activity and IL-6 secretion

Keywords: NF-κB; nuclear factor-kappaB; mapk; mitogen-activated protein kinase; PI3K; phosphatidylinositide 3-kinase; Akt; protein kinase B; FAK; focal adhesion kinase; PSG; prostate-specific G-protein-coupled receptor; IL-6; interleukin-6; JNK; c-Jun NH(2)-termin

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Melittin suppresses EGF-induced cell motility and invasion by inhibiting PI3K/Akt/mTOR signaling pathway in breast cancer cells

Keywords: Bee venom; Melittin; FAK; MMP; Cancer invasion;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

The role of VLA-4 binding for experimental melanoma metastasis and its inhibition by heparin

Keywords: FCS; fetal calf serum; FAK; focal adhesion kinase; LMWH; low molecular weight heparin; mAb; monoclonal Antibody; PBS; phosphate-buffered saline; PE labeled; Phycoerythrin labeled; PKCα; protein kinase C alpha; UFH; unfractionated heparin; VCAM-1; vascula

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

A putative role of p53 pathway against impulse noise induced damage as demonstrated by protection with pifithrin-alpha and a Src inhibitor

Keywords: ABR; auditory brainstem response; ANOVA; analysis of variance; DMSO; dimethyl sulfoxide; ECM; extra-cellular matrix; FAK; focal adhesion kinase; OHC; outer hair cell; PBS; phosphate buffered saline; PFT; pifithrin alpha; PI; propidium iodide; PTK; protein

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Lysyl oxidase-like 2 (LOXL2) controls tumor-associated cell proliferation through the interaction with MARCKSL1

Keywords: LOXL2; lysyl oxidase-like 2; MARCKSL1; myristoylated alanine-rich C kinase substrate-like 1; EMT; epithelial-mesenchymal transition; ECM; extracellular matrix; FAK; focal adhesion kinase; PKC; protein kinase C; siRNA; small interfering RNA; ONPG; o-nitr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Radiation sensitization of tumor cells induced by shear stress: The roles of integrins and FAK

Keywords: Radiation; Shear stress; Integrin; FAK;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Down regulation of RhoC by microRNA-138 results in de-activation of FAK, Src and Erk1/2 signaling pathway in head and neck squamous cell carcinoma

Keywords: RhoC; Head and neck cancer; miR-138; FAK; Src; Erk1/2

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

High-throughput molecular profiling of a P-cadherin overexpressing breast cancer model reveals new targets for the anti-cancer bacterial protein azurin

Keywords: E-cad; E-cadherin (or epithelial cadherin); ECM; extracellular matrix; EGFR; epidermal growth factor receptor; CXCR1; chemokine (C-X-C) receptor 1; FAK; focal adhesion kinase; CCR4; chemokine (C-C motif) receptor 4; CXCR4; chemokine (C-X-C) receptor 4; MM

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

CD68+HLA-DR+ M1-like macrophages promote motility of HCC cells via NF-κB/FAK pathway

Keywords: FAK; NF-κB; Hepatocellular carcinoma; Tumor-associated macrophage;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

The involvement of FAK and Src in the invasion of cardiomyocytes by Trypanosoma cruzi

Keywords: FAK; c-Src; Trypanosoma cruzi; Cardiomyocytes; Invasion; Signaling pathway;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

RUNX2 is overexpressed in melanoma cells and mediates their migration and invasion

Keywords: Melanoma; Transcription factor; RUNX2; FAK; Migration; Cholecalciferol (Vitamin D3);

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Potential Significance of EMP3 in Patients with Upper Urinary Tract Urothelial Carcinoma: Crosstalk with ErbB2-PI3K-Akt Pathway

Keywords: urinary bladder; urothelium; carcinoma; EMP3 protein; human; prognosis; EMP3; epithelial membrane protein 3; FAK; focal adhesion kinase; PCR; polymerase chain reaction; ROCK; Rho-associated coiled-coil containing protein kinase; RT-PCR; real-time PCR; TCC

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Bioengineering 3D environments for cancer models

Keywords: EMT; epithelial-mesenchymal transition; ECM; extracellular matrix; 2D; two-dimensional; 3D; three-dimensional; PEG; polyethylene glycol; PLG; poly(lactide-co-glycolide); PLA; polylactic acid; RGD; arginine-glycine-aspartate peptide sequence; MMPs; m

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

PTEN inhibits the invasion and metastasis of gastric cancer via downregulation of FAK expression

Keywords: PTEN; phosphatase and tensin homolog; FAK; focal adhesion kinase; AKT; protein kinase B; NF-κB; nuclear factor B or NF-kappaB; ChIP; chromatin immunoprecipitation; EMSA; electrophoretic mobility shift assay; DAPI; 4′,6-diamidino-2-phenylindole; Focal a

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Matrikines from basement membrane collagens: A new anti-cancer strategy

Keywords: ECM; extracellular matrix; MMP; matrix metalloproteinases; SDF-1; Stroma-Derived Factor 1; CAFs; cancer-Associated Fibroblasts; ROS; reactive oxygen species; EMT; epithelial-mesenchymal transition; NC domain; non-collagenous domain; FACIT; fibril associ

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Associate editor: B. TeicherThe role of FAK in tumor metabolism and therapy

Keywords: Focal adhesion kinase; Lipogenesis; Glutamine; Proliferation; Motility; Molecular targeting; FAK; focal adhesion kinase; FASN; fatty acid synthase; IGF1R; insulin-like growth factor 1 receptor; ACLY; ATP citrate lyase; ECM; extracellular matrix; IRS; insu

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Heat shock protein 90β stabilizes focal adhesion kinase and enhances cell migration and invasion in breast cancer cells

Keywords: HSP90β; FAK; Breast cancer; Metastasis; Ubiquitin;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

The effect of type II collagen on MSC osteogenic differentiation and bone defect repair

Keywords: Mesenchymal stem cell; Type II collagen; Osteogenesis; Cell adhesion; Integrin signaling; Bone healing; BMSC; bone marrow derived mesenchymal stem cell; ECM; extracellular matrix; VLA-2; very late antigen-2 (integrin α2β1 complex); FAK; focal adhesion k

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

MicroRNA-dependent targeting of the extracellular matrix as a mechanism of regulating cell behavior

Keywords: ceRNA; competing endogenous RNA; ECM; extracellular matrix; EMT; epithelial-to-mesenchymal transition; FAK; focal adhesion kinase; FGF; fibroblast growth factor; HS; Heparan sulfate; HSPG2; heparan sulfate proteoglycan 2, perlecan; IL; interleukin; LDL; L

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Sialosignaling: Sialyltransferases as engines of self-fueling loops in cancer progression

Keywords: ALL; acute lymphocytic leukemia; AML; acute myeloblastic leukemia; 5-AZA; 5′-azacytidine; BCG; Bacillus Calmette-Guerin; CIN; chromosome instability; DP; degree of polymerization; ECM; extracellular matrix; EGF; epidermal growth factor; EGFR; epiderma

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Monosaccharide digitoxin derivative sensitize human non-small cell lung cancer cells to anoikis through Mcl-1 proteasomal degradation

Keywords: Bcl-2; B-cell lymphoma 2; Casp-3; caspase-3; CHX; cycloheximide; CG; cardiac glycoside; DMSO; dimethyl sulfoxide; D6-MA; α-l-rhamnose monosaccharide derivative; ECM; extracellular matrix; ERK; extracellular signal-regulated protein kinase; FAK; focal adh

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Regulation of chondrogenesis by protein kinase C: Emerging new roles in calcium signalling

Keywords: ADAMTS; a disintegrin and metalloproteinase with thrombospondin motifs; ADSC; adipose-derived stem cell; ATP; adenosine triphosphate; BMP; bone morphogenic protein; cAMP; cyclic adenosine monophosphate; COMP; cartilage oligomeric matrix protein; CREB; cAM

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2014 سفارش ترجمه

RACK1 promotes neurite outgrowth by scaffolding AGAP2 to FAK

Keywords: FAK; focal adhesion kinase; IGF-I; insulin-like growth factor I; Erk; extracellular signal-regulated kinase; GAP; GTPase-activating protein; AGAP; Arf GAP with G protein-like domain (GLD), ankyrin repeat, and PH domain; PBS; phosphate-buffered saline; siR

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2014 سفارش ترجمه

miRNA-7-5p inhibits melanoma cell migration and invasion

Keywords: miRNA; microRNA; IRS-2; insulin receptor substrate-2; IRS-1; insulin receptor substrate-1; PI3K; phosphatidylinositol 3-kinase; Akt; protein kinase B; RT-qPCR; reverse transcription and quantitative polymerase chain reaction; BRAF; v-Raf murine sarcoma vi

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Atorvastatin inhibited Rho-associated kinase 1 (ROCK1) and focal adhesion kinase (FAK) mediated adhesion and differentiation of CD133+CD44+ prostate cancer stem cells

Keywords: Prostate cancer stem cell; ROCK1; FAK; Integrin; Differentiation and signaling cascade;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Deletion of the calmodulin-binding domain of Grb7 impairs cell attachment to the extracellular matrix and migration

Keywords: AEBSF; 4-(2-aminoethyl)-benzenesulfonyl fluoride; CaM; calmodulin; CaM-BD; calmodulin-binding domain; BPS; between PH and SH2; DAPI; 4′,6-diamidino-2-phenylindole; DMEM; Dulbecco′s modified Eagle′s medium; E-64; N-[N- (L-3-trans-carboxyirane-2-carbo

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

STAT3 interacts with Skp2/p27/p21 pathway to regulate the motility and invasion of gastric cancer cells

Keywords: Ace-tubulin; Acetylated-tubulin; ANOVA; analysis of variance; DAPI; 4′,6-diamidino-2-phenylindole; E-cad; E-cadherin; ELISA; enzyme-linked immunosorbent assay; FAK; focal adhesion kinase; FITC; fluorescein isothiocyanate; GAPDH; glyceraldehyde-3-phospha

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

HER2 regulates Brk/PTK6 stability via upregulating calpastatin, an inhibitor of calpain

Keywords: ALLN; N-acetyl-leucyl-leucyl-norleucinal; Brk; breast tumor kinase; CHX; cycloheximide; DMEM; Dulbecco's modified Eagle's medium; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; Erk; extracellular signal-regulated kinase; FAK;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Rapid activation of FAK/mTOR/p70S6K/PAK1-signaling controls the early testosterone-induced actin reorganization in colon cancer cells

Keywords: DEX; Dexamethasone; FAK; Focal Adhesion Kinase; HSA; human serum albumin; iAR; intracellular androgen receptor; mTOR; mammalian target of rapamycin; mAR; membrane androgen receptor; PAK1; p21-activated kinase 1; p70S6K; S6 kinase; PFA; paraformaldehyde; P

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Transcriptional profiling in rats and an ex vivo analysis implicate novel beneficial function of egg shell membrane in liver fibrosis

Keywords: α-Sma; smooth muscle-α-actin; BHLHB2; basic helix-loop-helix domain containing class B2; COL1A1; collagen, type I, alpha 1; COL1A2; collagen, type I, alpha 2; CYP7A1; cytochrome P450 Family 7 Subfamily A Polypeptide 1; DMEM; Dulbecco's modified eagleâ

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

A diterpenoid compound, excisanin A, inhibits the invasive behavior of breast cancer cells by modulating the integrin β1/FAK/PI3K/AKT/β-catenin signaling

Keywords: Excisanin A; Diterpenoid; Invasion; MMPs; Integrin β1; FAK;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Suppression of Src/ERK and GSK-3/β-catenin signaling by pinosylvin inhibits the growth of human colorectal cancer cells

Keywords: FAK; focal adhesion kinase; ERK; extracellular signal-regulated kinase; PI3K; phosphoinositide 3-kinase; GSK-3β; glycogen synthase kinase-3β; BMP4; bone morphogenetic protein 4; ID2; DNA-binding protein inhibitor 2; Pinosylvin; Anti-proliferation; FAK/c

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

β-Adrenergic system, a backstage manipulator regulating tumour progression and drug target in cancer therapy

Keywords: FAK; focal adhesion kinase; PKA; protein kinase A; BAD; BCL2-associated death protein; VEGF; vascular endothelial growth factor; PlGF; placenta-derived growth factor; PDGF; platelet-derived growth factor; TGF-β; transforming growth factor β; HIF-1α; hy

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Activation of integrin β1-focal adhesion kinase-RasGTP pathway plays a critical role in TGF beta1-induced podocyte injury

Keywords: TGFβ1; Integrin; FAK; Grb2; GTP-Ras; Podocyte apoptosis;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

4F2hc-silencing impairs tumorigenicity of HeLa cells via modulation of galectin-3 and β-catenin signaling, and MMP-2 expression

Keywords: ECM; extracellular matrix; EmGFP; emerald green fluorescent protein; EMT; epithelial-mesenchymal transition; ERK; extracellular signal-regulated kinase; FACS; fluorescence-activated cell sorting; FAK; focal adhesion kinase; FN; fibronectin; FRET; fluore

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

β1-Integrin cytoskeletal signaling regulates sensory neuron response to matrix dimensionality

Keywords: DRG; dorsal root ganglion; ECM; extracellular matrix; FAK; focal adhesion kinase; FAKpY397; FAK phosphorylation at tyrosine 397; FAKpY861; FAK phosphorylation at tyrosine 861; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; HRP; horseradish peroxidase; N

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

The dioxin receptor controls β1 integrin activation in fibroblasts through a Cbp-Csk-Src pathway

Keywords: AMD; accumulated mean distance; AhR; dioxin receptor; Cav1; Caveolin 1; Cbp/Pag1 (Cbp); C-terminal Src kinase (Csk)-binding protein; ECM; extracellular matrix; EMD; Euclidean mean distance; FAK; focal adhesion kinase; FGM; immortalized mouse fibroblasts;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

The Src homology 2 protein Shb promotes cell cycle progression in murine hematopoietic stem cells by regulation of focal adhesion kinase activity

Keywords: 5-FU; 5-fluorouracil; BrdU; 5-bromo-2′-deoxyuridine; FACS; fluorescence activated cell sorting; FAK; focal adhesion kinase; GMP; granulocyte-monocyte progenitor; HPC; hematopoietic progenitor cell; KLS; c-Kit+lineage−Sca-1+; LT-HSC; long-term hemato

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Synthesis, biological evaluation, and molecular docking studies of novel 1,3,4-oxadiazole derivatives possessing benzotriazole moiety as FAK inhibitors with anticancer activity

Keywords: Benzotriazole; 1,3,4-Oxadiazole derivatives; FAK; Molecular docking; Anticancer activity;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2013 سفارش ترجمه

Elevated Concentration of Microvesicles Isolated from Peripheral Blood in Breast Cancer Patients

Keywords: Breast cancer; Microvesicles; EGFR; FAK

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

ErbB/integrin signaling interactions in regulation of myocardial cell–cell and cell–matrix interactions

Keywords: Neuregulin; Nrg1β; FAK; Integrin; Cardiomyocyte; Heart

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Intersecting roles of protein tyrosine kinase and calcium signaling during fertilization

Keywords: Fertilization; Oocyte; Calcium; SRC; FYN; YES; FGR; FAK; PYK2; Protein kinase

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Epigallocatechin-3 gallate inhibits cancer invasion by repressing functional invadopodia formation in oral squamous cell carcinoma

Keywords: EGCG; Invadopodia formation; Src; Cortactin; FAK; RhoA activation

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

CB1 cannabinoid receptors promote maximal FAK catalytic activity by stimulating cooperative signaling between receptor tyrosine kinases and integrins in neuronal cells

Keywords: 2-AG; 2-arachidonoylglycerol; BSA; bovine serum albumin; CB1; CB1 cannabinoid receptor; Csk; C-terminal Src kinase; DAGL; diacylglycerol lipase; DTT; dithiothreitol; ECM; extracellular matrix; ERK1/2; extracellular signal-regulated kinases 1 and 2; EGFR;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه