دانلود مقالات ISI درباره Farnesoid X گیرنده + ترجمه فارسی

Tunicate pregnane X receptor (PXR) orthologs: Transcript characterization and natural variation

Keywords: Farnesoid X گیرنده; AF-1; transcription activation function 1; AR; androgen receptor; BsVDR/PXRα; Botryllus schlosseri VDR/PXR ortholog α; BSA; bovine serum albumin; bp; base pair; CAR; constitutive androstane receptor; CiVDR/PXRα; Ciona intestinalis VDR/PXR ortholog α;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Boldine enhances bile production in rats via osmotic and Farnesoid X receptor dependent mechanisms

Keywords: Farnesoid X گیرنده; Boldine; Bile production; Bile salt export pump; Farnesoid X receptor

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Fragmentation of GW4064 led to a highly potent partial farnesoid X receptor agonist with improved drug-like properties

Keywords: Farnesoid X گیرنده; Metabolic disorders; Nuclear receptors; Farnesoid X receptor; FXR agonists; Fluorescent FXR ligand;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Oleanolic acid attenuates obstructive cholestasis in bile duct-ligated mice, possibly via activation of NRF2-MRPs and FXR antagonism

Keywords: Farnesoid X گیرنده; OA; oleanolic acid; LCA; lithocholic acid; UDCA; ursodeoxycholic acid; PBC; primary biliary cirrhosis; PSC; primary sclerosing cholangitis; MRP; multidrug resistance-associated protein; NRF2; nuclear factor-E2-related factor; siRNA; small interfering RNA;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2015 سفارش ترجمه

Stereoselective synthesis, biological evaluation, and modeling of novel bile acid-derived G-protein coupled Bile acid receptor 1 (GP-BAR1, TGR5) agonists

Keywords: Farnesoid X گیرنده; GPCR; G protein-coupled receptor; BAs; bile acids; CDCA; chenodeoxycholic acid; CA; cholic acid; LCA; lithocholic acid; UDCA; ursodeoxycholic acid; FXR; farnesoid X receptor; NRs; nuclear receptors; LBD; ligand-binding domain; cAMP; cyclic adenosine monop

دانلود رایگان متن کامل مقاله ISI 62 صفحه سال انتشار : 2015 سفارش ترجمه

A farnesoid X receptor polymorphism predisposes to spontaneous bacterial peritonitis

Keywords: Farnesoid X گیرنده; Ascites; Farnesoid X receptor; Liver cirrhosis; Spontaneous bacterial peritonitis

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Activation of farnesoid X receptor induces RECK expression in mouse liver

Keywords: Farnesoid X گیرنده; FXR; farnesoid X receptor; RXRα; retinoid X receptor α; SHP; small heterodimer partner; SREBP-1c; sterol regulatory element-binding protein-1c; PEPCK; phosphoenolpyruvate carboxykinase; RECK; reversion-inducing cysteine rich protein with Kazal motifs; M

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Activation of farnesoid X receptor attenuates hepatic injury in a murine model of alcoholic liver disease

Keywords: Farnesoid X گیرنده; FXR; farnesoid X receptor; ALD; alcoholic liver disease; SHP; small heterodimer partner; BSEP; bile salt export pump; CYP7A1; cholesterol 7α-hydroxylase; CYP8B1; sterol 12α-hydroxylase; ADH; alcohol dehydrogenase; ALDH; aldehyde dehydrogenase; CYP2E1; c

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

SREBP-2 negatively regulates FXR-dependent transcription of FGF19 in human intestinal cells

Keywords: Farnesoid X گیرنده; ChIP; chromatin immunoprecipitation; DR-1; direct repeat separated by 1 nucleotide; EMSA; electrophoretic mobility shift assay; ER-8; everted repeat separated by 8 nucleotides; FXR; farnesoid X receptor; FGF19; fibroblast growth factor 19; GST; glutathion

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Activation of farnesoid X receptor (FXR) protects against fructose-induced liver steatosis via inflammatory inhibition and ADRP reduction

Keywords: Farnesoid X گیرنده; NAFLD; nonalcoholic fatty liver disease; FXR; farnesoid X receptor; LPS; lipopolysaccharide; WAY; WAY362450; ADRP; adipose differentiation-related protein; PA; palmitic acid; AP-1; activator protein-1; qPCR; quantitative polymerase chain reaction; NASH; n

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Potential synergistic effects of Chinese herbal prescription FTZ components detected in blood towards hepatic lipid-modulating targets

Keywords: Farnesoid X گیرنده; TCM; traditional Chinese medicine; UPLC/Q-TOF-MS; ultra-performance liquid chromatography/quadruple-time-of-flight mass-spectrometry; RC; Rhizoma Coptidis; RSM; Radix Salvia Miltiorrhiza; TC; total cholesterol; TG; total triglyceride; LDL-C; low density l

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Vitamin D receptor is highly expressed in precancerous lesions and esophageal adenocarcinoma with significant sex difference

Keywords: Farnesoid X گیرنده; BE; Barrett esophagus; CCM; columnar cell metaplasia; EAC; esophageal adenocarcinoma; ESCC; esophageal squamous cell carcinoma; FXR; farnesoid X receptor; HGD; high-grade dysplasia; IHC; immunohistochemical; LGD; low-grade dysplasia; SE; squamous epitheli

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Research ArticleHepatic steatosis exacerbated by endoplasmic reticulum stress-mediated downregulation of FXR in aging mice

Keywords: Farnesoid X گیرنده; NAFLD; Non-alcoholic fatty liver disease; TG; triglyceride; ER; endoplasmic reticulum; THA; thapsigargin; Tun; tunicamycin; TUDCA; tauroursodeoxycholate; MPH; mouse primary hepatocyte; FXR; farnesoid X receptor; HNF1α; hepatocyte nuclear factor 1 alpha;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

The FXR agonist 6ECDCA reduces hepatic steatosis and oxidative stress induced by ethanol and low-protein diet in mice

Keywords: Farnesoid X گیرنده; AHS; alcoholic hepatic steatosis; FXR; farnesoid X receptor; 6ECDCA; 6α-ethyl-chenodeoxycholic acid; AST; aspartate aminotransferase; ALT; alanine aminotransferase; TG; triglyceride; Cat; catalase; GST; glutathione-S-transferase; SOD; superoxide dismutas

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Emerging therapies for raising high-density lipoprotein cholesterol (HDL-C) and augmenting HDL particle functionality

Keywords: Farnesoid X گیرنده; apoA-I mimetic; coronary artery disease; delipidation; endothelial lipase inhibitor; farnesoid X receptor; high-density lipoproteins; liver X receptor; reverse cholesterol transport; RVX-208

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Conformational dynamics of human FXR-LBD ligand interactions studied by hydrogen/deuterium exchange mass spectrometry: Insights into the antagonism of the hypolipidemic agent Z-guggulsterone

Keywords: Farnesoid X گیرنده; HDX; hydrogen/deuterium exchange; LC-ESI-MS; liquid chromatography electrospray ionization mass spectrometry; FXR-LBD; farnesoid X receptor ligand binding domain; LBC; ligand binding cavity; CDCA; chenodeoxycholic acid; GG; Z-guggulsterone; 6ECDCA; 6-et

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Research ArticleAltered FXR signalling is associated with bile acid dysmetabolism in short bowel syndrome-associated liver disease

Keywords: Farnesoid X گیرنده; SBS; short bowel syndrome; SBS-ALD; short bowel syndrome-associated liver disease; PN; parenteral nutrition; SBR; small bowel resection; BA; bile acid; FXR; farnesoid X receptor; SHP; small heterodimer partner; FGF19; fibroblast growth factor 19; CYP7A1;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Intestine-Specific Deletion of SIRT1 in Mice Impairs DCoH2-HNF-1α-FXR Signaling and Alters Systemic Bile Acid Homeostasis

Keywords: Farnesoid X گیرنده; Ileal Bile Acid Absorption; Bile Acid Synthesis; Liver Damage; Cholestasis; CA; cholic acid; DCoH2; dimerization cofactor of hepatocyte nuclear factor 1α 2; FGF15; fibroblast growth factor 15; FXR; farnesoid X receptor; HA; hemagglutinin; HNF-1α; hepato

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Human cytochrome P450 epoxygenases: Variability in expression and role in inflammation-related disorders

Keywords: Farnesoid X گیرنده; Inflammation; Cytochrome P450; Epoxygenase; Epoxyeicosatrienoic acids; Variability; AA; arachidonic acid; AhR; aryl hydrocarbon receptor; AP-1; activator protein-1; bZIP; basic leucine zipper; CAR; constitutive androstane receptor; CCRP; cytoplasmic CAR r

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2014 سفارش ترجمه

Vitamin D Receptor Activation Down-regulates the Small Heterodimer Partner and Increases CYP7A1 to Lower Cholesterol

Keywords: Farnesoid X گیرنده; Liver; Bile Acid; Farnesoid X Receptor; Transcriptional Regulation; Asbt; rodent apical sodium dependent bile acid transporter; CDCA; chenodeoxycholic acid; ChIP; chromatin immunoprecipitation; Cyp7a1/CYP7A1; rodent/human cholesterol 7α-hydroxylase; 1,25

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2014 سفارش ترجمه

Cholestatic effect of epigallocatechin gallate in rats is mediated via decreased expression of Mrp2

Keywords: Farnesoid X گیرنده; Epigallocatechin gallate; Bile formation; Cholestasis; Bile acids; Asbt; apical sodium-dependent bile salt transporter; ALT; alanine transaminase; AST; aspartate transaminase; Bsep; bile salt exporting pump; CDCA; chenodeoxycholic acid; Cyp7a1; cholestero

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Small heterodimer partner overexpression partially protects against liver tumor development in farnesoid X receptor knockout mice

Keywords: Farnesoid X گیرنده; ALT; alanine aminotransferase; GP130; glycoprotein 130; JAK; Janus kinases; FXR; farnesoid X receptor; FXR−/−; FXR knockout; HCC; hepatocellular carcinoma; IL-1α; interleukin-1α; IL-1β; interleukin-1β; IL-6; interleukin-6; Q-PCR; quantitative real

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Upregulation of thrombomodulin expression by activation of farnesoid X receptor in vascular endothelial cells

Keywords: Farnesoid X گیرنده; Farnesoid X receptor; Thrombomodulin; Vascular endothelial cell; Inflammation; Gene regulation;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Effect of pigeon pea (Cajanus cajan L.) on high-fat diet-induced hypercholesterolemia in hamsters

Keywords: Farnesoid X گیرنده; apo-A1; apolipoprotein-A1; bw; body weight; CAT; catalase; CDNB; 1-chloro-2,4-dinitrobenzene; CPT-1; carnitine palmitoyltransferase-1; CYP7A1; cytochrome P450 7A1; DTNB; 5,5-dithiobis[2-nitrobenzoic acid]; EDTA; ethylenediaminetetraacetic acid; FXR; farne

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Activation of the nuclear receptor FXR enhances hepatocyte chemoprotection and liver tumor chemoresistance against genotoxic compounds

Keywords: Farnesoid X گیرنده; FXR; farnesoid X receptor; HCC; hepatocellular carcinoma; MOC; mechanisms of chemoresistance; RXR; retinoid X receptor; TLDA; Taqman low density array; Bile acid; Cancer; Chemotherapy; Drug; Liver; Pharmacology;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

CCAAT/enhancer-binding protein β is involved in the breed-dependent transcriptional regulation of 3β-hydroxysteroid dehydrogenase/Δ5-Δ4-isomerase in adrenal gland of preweaning piglets

Keywords: Farnesoid X گیرنده; 3β-HSD; 3β-hydroxysteroid dehydrogenase/Δ5-Δ4-isomerase; AGP; α1-acid glycoprotein; AR; androgen receptor; ARE; androgen response element; C/EBPβ; CCAAT/enhancer binding protein β; ChIP; chromatin immunoprecipitation; COX-2; cyclooxygenase 2; DAX-1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Farnesoid X receptor directly regulates xenobiotic detoxification genes in the long-lived Little mice

Keywords: Farnesoid X گیرنده; FXR; farnesoid X receptor; RXR; retinoid X receptor; Ghrhr; growth hormone-releasing hormone receptor; GH; growth hormone; IGF; insulin-like growth factor; FXREs; FXR response elements; IR; inverted repeat; DR; direct repeat; ER; everted repeat; TSS; tran

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Identification of 15d-PGJ2 as an antagonist of farnesoid X receptor: Molecular modeling with biological evaluation

Keywords: Farnesoid X گیرنده; 15d-PGJ2; 15-deoxy-Δ12,14-PGJ2; AA; arachidonic acid; PPARγ; peroxisome proliferator-activated receptor γ; FXR; farnesoid X receptor; SPR; surface plasmon resonance; FQ; fluorescence quenching; HTRF; homo time-resolved fluorescence; BSEP; bile-salt exp

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Disruption of Stard10 gene alters the PPARα-mediated bile acid homeostasis

Keywords: Farnesoid X گیرنده; StAR; steroidogenic acute regulatory protein; START; StAR-related lipid transfer; STARD10/Stard10; START domain containing 10; WT; wild type; ASBT/Asbt; apical sodium dependent bile acid transporter; STARD2/Stard2; START domain containing 2; CA; cholic ac

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Vitamin D receptor signaling mechanisms: Integrated actions of a well-defined transcription factor

Keywords: Farnesoid X گیرنده; 1α,25(OH)2D3; 1α,25-dihydroxyvitamin D3; 25(OH)D3; 25-hydroxyvitamin D3; ALOX5; arachidonate 5-lipoxygenase; AR; androgen receptor; CAMP; cathelicidin anti-microbial peptide; CCNC; cyclin C; CDKN1A; cyclin-dependent kinase inhibitor 1A; CoA; co-activato

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Development of time resolved fluorescence resonance energy transfer-based assay for FXR antagonist discovery

Keywords: Farnesoid X گیرنده; FXR; farnesoid X receptor; NRs; nuclear receptors; HTS; high-throughput screen; LBD; ligand-binding domain; TR-FRET; time resolved fluorescence resonance energy transfer;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Differential activation of the human farnesoid X receptor depends on the pattern of expressed isoforms and the bile acid pool composition

Keywords: Farnesoid X گیرنده; Glycoconjugated bile acids; Tauroconjugated bile acids; Ileum; Liver; Nuclear receptor; ACA; allocholic acid; BA; bile acid; BSEP; bile salt export pump; CDCA; chenodeoxycholic acid; CA; cholic acid; DCA; deoxycholic acid; FGF; fibroblast growth factor; F

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Analytical strategies for characterization of oxysterol lipidomes: Liver X receptor ligands in plasma

Keywords: Farnesoid X گیرنده; API; atmospheric pressure ionization; CDCA; chenodeoxycholic acid; CTX; cerebrotendinous xanthomatosis; EADSA; enzyme-assisted derivatization for sterol analysis; DHEA; dehydroepiandrosterone; ESI; electrospray ionization; FT; Fourier transform; FWHM; ful

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation

Keywords: Farnesoid X گیرنده; Biotransformation; Cytochrome P450 monooxygenase; NADPH:cytochrome P450 reductase; Pharmacogenetics; Polymorphism; Xenobiotic; ADME; absorption, distribution, metabolism, excretion; ADR; adverse drug reaction; AhR; aromatic hydrocarbon receptor; CNV; copy

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2013 سفارش ترجمه

Modulation of farnesoid X receptor results in post-translational modification of poly (ADP-ribose) polymerase 1 in the liver

Keywords: Farnesoid X گیرنده; 2D-DIGE; two-dimensional gel electrophoresis; Alc1; amplified in liver cancer 1; Aldh2; mitochondrial aldehyde dehydrogenase 2; CDCA; chenodeoxycholic acid; Eno1; enolase1; FXR; farnesoid X receptor; FXR-KO; FXR-knockout; HBVCP; HBV core promoter; HCC; he

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Serum bile acids and leptin interact with glucose metabolism in patients with liver cirrhosis

Keywords: Farnesoid X گیرنده; Hepatogenous diabetes; Leptin; TGR-5; Farnesoid X receptor; Deoxycholic acid; Chenodeoxycholic acid; Cholic acidLC, liver cirrhosis; BA, bile acids; CA, cholic acid; DC, deoxycholic acid; CDC, chenodeoxycholic acids; HOMA, homeostasis model assessment; TI

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Efficacy and Safety of the Farnesoid X Receptor Agonist Obeticholic Acid in Patients With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease

Keywords: Farnesoid X گیرنده; Clinical Trial; Metabolic Syndrome; Treatment; Obesity; ALT; alanine aminotransferase; AST; aspartate aminotransferase; BA; bile acid; C4; 7α-hydroxy-4-cholesten-3-one; FGF; fibroblast growth factor; FXR; farnesoid X receptor; GIR; glucose infusion rate;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Implication of intestinal VDR deficiency in inflammatory bowel disease

Keywords: Farnesoid X گیرنده; VDR; vitamin D receptor; IBD; inflammatory bowel disease; ALP; alkaline phosphatase; ALT; alanine aminotransferase; qPCR; quantitative polymerase chain reaction; UPLC-ESI-QTOFMS; ultra-performance liquid chromatography-electrospray ionization-quad

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

FXR signaling in the enterohepatic system

Keywords: Farnesoid X گیرنده; Nuclear receptors; Farnesoid X receptor; Bile acids; Cholestasis; Liver disease; Enterohepatic circulationASBT, apical sodium dependent transporter; CA, cholic acid; CDCA, chenodeoxycholic acid; CREB, cAMP regulatory element-binding protein; DCA, deoxycho

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Sesquiterpenoids from Atractylodes macrocephala act as farnesoid X receptor and progesterone receptor modulators

Keywords: Farnesoid X گیرنده; Atractylodes macrocephala (Asteraceae); Farnesoid X receptor; Progesterone receptor

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

E297G mutated bile salt export pump (BSEP) function enhancers derived from GW4064: Structural development study and separation from farnesoid X receptor-agonistic activity

Keywords: Farnesoid X گیرنده; Bile salt export pump; Bile acid; Farnesoid X receptor; Mutant;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Farnesoid X Receptor Targeting for Hepatitis C: Study Protocol for a Proof-of-concept Trial

Keywords: Farnesoid X گیرنده; clinical trial; farnesoid X receptor; hepatitis C; proof of concept; essai clinique; récepteur nucléaire des acides biliaires; hépatite C; preuve de concept; Afssaps; french Agency for the Safety of Health Products (currently ANSM); BA; bile acid; CBC;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Triterpenes from Alisma orientalis act as farnesoid X receptor agonists

Keywords: Farnesoid X گیرنده; Alisma orientalis; Farnesoid X receptor

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Complement factor C5 deficiency significantly delays the progression of biliary fibrosis in bile duct-ligated mice

Keywords: Farnesoid X گیرنده; α-SMA; alpha-smooth muscle actin; BA; bile acid; BDL; bile duct ligation; Col; collagen; FXR; farnesoid X receptor; HE; Hematoxilin&Eosin; Ntcp; Na-dependent taurocholate transporter; MMP; matrix metalloproteinase; Mrp; multidrug resistance associated pr

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticleMouse organic solute transporter alpha deficiency alters FGF15 expression and bile acid metabolism

Keywords: Farnesoid X گیرنده; BA; bile acid(s); Asbt; apical sodium-dependent bile acid transporter; Ost; organic solute transporter; FXR; farnesoid X receptor; FGF15; fibroblast growth factor 15; Cyp7a1; cholesterol 7α-hydroxylase; FGFR4; fibroblast growth factor receptor 4; CA; cho

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticleLack of Abcc3 expression impairs bile-acid induced liver growth and delays hepatic regeneration after partial hepatectomy in mice

Keywords: Farnesoid X گیرنده; BA; bile acids; PH; partial hepatectomy; Mrp3; multi drug resistance-associated protein 3; CA; cholic acid; FXR; farnesoid X receptor; EGF; epidermal growth factor; Cyp7a1; cholesterol 7-alpha hydroxylase; Ntcp; Na+-taurocholate cotransporting protein; Bs

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticleSRC-3 is required for CAR-regulated hepatocyte proliferation and drug metabolism

Keywords: Farnesoid X گیرنده; SRC; steroid receptor co-activator; NR; nuclear receptor; CAR; constitutive androstane receptor; TCPOBOP; 1,4-bis-[2-(3,5-dichloropyridyloxy)] benzene; ASC-2; activating signal cointegrator 2; FXR; farnesoid X receptor; PCNA; proliferating cell nuclear an

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticleEffect of ursodeoxycholic acid on bile acid profiles and intestinal detoxification machinery in primary biliary cirrhosis and health

Keywords: Farnesoid X گیرنده; UDCA; ursodeoxycholic acid; PBC; primary biliary cirrhosis; ASBT; apical sodium-dependent bile acid transporter; FXR; farnesoid X receptor; PXR; pregnane X receptor; VDR; vitamin D receptor; CA; cholic acid; CDCA; chenodeoxycholic acid; DCA; deoxycholic a

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticleDeletion of IFNγ enhances hepatocarcinogenesis in FXR knockout mice

Keywords: Farnesoid X گیرنده; HCC; hepatocellular carcinoma; FXR; farnesoid X receptor; DEN; diethylnitrosamine; AST; aspartate aminotransferase; ALT; alanine aminotransferase; ROS; reactive oxygen species; FXR; HCC; STAT3; JNK; NF-κB; p53;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Dancing with the sterols: Critical roles for ABCG1, ABCA1, miRNAs, and nuclear and cell surface receptors in controlling cellular sterol homeostasis

Keywords: Farnesoid X گیرنده; ABC; ATP Binding Cassette; AICAR; Aminoimidazole Carboxamide Ribonucleotide; ApoE; Apolipoprotein E; ApoER2; ApoE receptor 2 (LRP8); AR; Androgen Receptor; BAC; Bacterial Artificial Chromosome; CETP; Cholesterol Ester Transfer Protein; eNOS; endothelial N

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه