Keywords: salt-sensitive hypertension; Fas; Bcl-2; chronic renal failure; Dahl/Rapp rat; programmed cell death
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Keywords: Expert evidence; Brain injury; Developmental delay; Fetal alcohol spectrum disorder; FASD; FAS; Police interviews; Sentencing; Criminal responsibilityPreuve d’expertise; Dommages cérébraux; Retard de développement; Troubles du spectre de l’alcoolisation f
Lipid accumulation responses in the liver of Rana nigromaculata induced by perfluorooctanoic acid (PFOA)
Keywords: PFOA; perfluorooctanoic acid; PPARγ; peroxisome proliferator activated receptors γ; SREBP2; sterol regulatory element-binding protein 2; T-CHO; total cholesterol; TG; triglyceride; FAS; fatty acid synthase; ACC; acetyl-CoA carboxylase; GPAT; glycerol-3-
Global microRNA and isomiR expression associated with liver metabolism is induced by organophosphorus flame retardant exposure in male Chinese rare minnow (Gobiocypris rarus)
Keywords: OPFRs; Organophosphorus flame retardants; TBOEP; Tris(2âbutoxyethyl) phosphate; TDCIPP; Tris(1,3âdichloroâ2âpropyl) phosphate; TPHP; Triphenyl phosphate; BFRs; Brominated flame retardants; HTS; High-throughput sequencing; miRNA; MicroRNA; CTD; Com
Long-term effectiveness of aripiprazole once-monthly for schizophrenia is maintained in the QUALIFY extension study
Keywords: Aripiprazole once-monthly; Schizophrenia; Maintenance treatment; Quality of life; AE; adverse event; APTS; all-patients-treated set; AOM 400; aripiprazole once-monthly 400Â mg; CGI-S; Clinical Global Impressions-Severity; C-SSRS; Columbia Suicide Severity
Stereoselective effects of lactate enantiomers on the enhancement of 3T3-L1 adipocyte differentiation
Keywords: Lactic acid; Enantiomer; Enantioselectivity; Adipocyte differentiation; 3T3-L1 preadipocyte; cAMP-response element; CRE; CCAAT/enhancer-binding protein; C/EBP; dexamethasone; DEX; glycerol-3-phosphate dehydrogenase; GPDH; fatty acid synthase; FAS; 3-isobu
Ox40 regulates the conversion and suppressive function of double-negative regulatory T cells
Keywords: Tregs; regulatory T cells; DNT; double-negative regulatory T cells; mDCs; mature dendritic cells; KO; knockout; WT; wild type; Ox40-KO; Ox40 knockout; IL-2; interleukin 2; GM-CSF; granulocyte macrophage colony stimulating factor; CM; complete culture medi
Cloning and characterization of â6/â5 fatty acyl desaturase (Fad) gene promoter in the marine teleost Siganus canaliculatus
Keywords: ALA; α-linolenic acid (18:3n-3); AP1; activated protein 1; ARA; arachidonic acid (20:4n-6); C/EBP; CCAAT enhancer binding protein; DHA; docosahexaenoic acid (22:6n-3); DR1; direct repeat 1 element; EFA; essential fatty acid; EPA; eicosapentaenoic acid (2
MiR-183 promotes preadipocyte differentiation by suppressing Smad4 in goats
Keywords: PPARγ; peroxisome proliferator-activated receptor γ; C/EBPα; CCAAT/enhancer binding protein α; FAS; fatty acid synthase; TGFβ; transforming growth factor β; LRP6; low density lipoprotein receptor related protein 6; SREBP-1c; sterol regulatory elemen
MicroRNA-204-5p regulates 3T3-L1 preadipocyte proliferation, apoptosis and differentiation
Keywords: C/EBPα; CCAAT/enhancer-binding proteins; PPAR-γ; peroxisome proliferator activated receptor-γ coactivator; AP2; adipocyte fatty-acid binding protein 2; CDK4; cyclin dependent kinase 4; CDK2; cyclin dependent kinase 2; CDK5; cyclin dependent kinase 5; p
The CAR agonist TCPOBOP inhibits lipogenesis and promotes fibrosis in the mammary gland of adolescent female mice
Keywords: ACC; acetyl-CoA carboxylase; α-SMA; alpha-smooth muscle actin; CAR; constitutive androstane receptor; FAS; fatty acid synthase; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; G6pase; glucose-6-phosphatase; Gon-WAT; gonadal white adipose tissue; H&E; he
Analysis of the biosynthetic process of fatty acids in Thraustochytrium
Keywords: Thraustochytrium; Polyunsaturated fatty acid; Odd-chain fatty acid; Biosynthesis; PUFA synthase; DAG; diacylglycerol; DHA; docosahexaenoic acid; DPA; docosapentaenoic acid; FAS; fatty acid synthase; PL; phospholipid; SFA; saturated fatty acid; TAG; triacy
Cissus quadrangularis extract (CQR-300) inhibits lipid accumulation by downregulating adipogenesis and lipogenesis in 3T3-L1 cells
Keywords: ACC; acetyl-CoA carboxylase; AMPK; AMP-activated protein kinase; aP2; fatty acid binding protein (aP2); BCS; bovine calf serum; C/EBPα; CCAAT/enhancer-binding protein α; CQR-300; Cissus quadrangularis extract; DMEM; Dulbecco's modified Eagle's mediu
Respiratory depression in low acuity hospital settings-Seeking answers from the PRODIGY trial
Keywords: AHRQ; Agency for Healthcare Research and Quality; APSF; Anesthesia Patient Safety Foundation; ASA; American Society of Anesthesiologists; CEC; Clinical Events Committee; DNR; do not resuscitate; ERAS; early recovery after surgery; CIP; clinical investigat
Cystic fibrosis epithelial cells are primed for apoptosis as a result of increased Fas (CD95)
Keywords: Epithelial cells; Apoptosis; Fas;
MicroRNA-200a regulates adipocyte differentiation in the domestic yak Bos grunniens
Keywords: DGAT; diacylglycerol acyltransferase; LPL; lipoprotein lipase; FABP4; fatty acid binding protein 4; SCD; stearoyl-CoA desaturase; FAS; fatty acid synthase; ACC; acetyl-coA carboxylase; ACS; acyl-CoA synthetase; C/EBPα; CCAAT/enhancer binding protein; PPA
A 6-week, multicenter, double-blind, double-dummy, chlorpromazine-controlled non-inferiorityrandomized phase iiitrial to evaluate the efficacy and safety of quetiapine fumarate (SEROQUEL) extended-release (XR) in the treatment of patients with schizophren
Keywords: AE; adverse event; ALT; alanine aminotransferase; CGI; Clinical Global Impression; DBP; diastolic blood pressure; DSM-IV; Diagnostic and Statistical Manual of Mental Disorders, 4th edition; EPS; extrapyramidal symptoms; FAS; full analysis set; IR; immedia
Evaluating the Impact of Intravitreal Aflibercept on Diabetic Retinopathy Progression in the VIVID-DME and VISTA-DME Studies
Keywords: BCVA; best-corrected visual acuity; DME; diabetic macular edema; DR; diabetic retinopathy; DRSS; Diabetic Retinopathy Severity Scale; ETDRS; Early Treatment Diabetic Retinopathy Study; FAS; full analysis set; NPDR; nonproliferative diabetic retinopathy; P
Fetal Alcohol Spectrum Disorder (FASD): Knowledge, attitudes, experiences and practices of the Western Australian youth custodial workforce
Keywords: Fetal alcohol spectrum disorder; FASD; Fetal alcohol syndrome; Youth justice; Juvenile detention; Officers; BHDC; Banksia Hill Detention Centre; DoJ; Department of Justice; FASD; Fetal Alcohol Spectrum Disorder; FAS; Fetal Alcohol Syndrome; ND-AE; Neurode
Oxidative stress and mitochondrial dysfunction mediated Cd-induced hepatic lipid accumulation in zebrafish Danio rerio
Keywords: ACOX; acyl-CoA oxidase; ATGL; adipose triacylglyceride lipase; CAT; catalase; Cd; cadmium; CPTI; carnitine palmitoyl transferase 1; COX; cytochrome c oxidase; CsA; cyclosporin A; FAS; fatty acid synthase; 6PGD; 6-phosphogluconate dehydrogenase; G6PD; gluc
Sustained Benefits from Ranibizumab for Central Retinal Vein Occlusion with Macular Edema: 24-Month Results of the CRYSTAL Study
Keywords: AE; adverse event; BCVA; best-corrected visual acuity; CFT; central foveal thickness; CRC; central reading center; CRVO; central retinal vein occlusion; CSFT; central subfield thickness; ETDRS; Early Treatment Diabetic Retinopathy Study; FAS; full analysi
Fas activity mediates airway inflammation during mouse adenovirus type 1 respiratory infection
Keywords: Adenovirus; Respiratory infection; CD8 T cells; Fas;
Efficacy and safety of the emedastine patch, a novel transdermal drug delivery system for allergic rhinitis: Phase III, multicenter, randomized, double-blinded, placebo-controlled, parallel-group comparative study in patients with seasonal allergic rhinit
Keywords: Emedastine; Randomized controlled trial; Seasonal allergic rhinitis; Sustained action; Transdermal drug delivery system; FAS; full analysis set; CI; confidence interval; Ig; immunoglobulin; LOCF; last observation carried forward; LSM; least squares mean;
Association study of apoptosis gene polymorphisms in mitochondrial diabetes: A potential role in the pathogenicity of MD
Keywords: BAK1; BCL2 Antagonist/Killer 1; BAX; BCL2 Associated X, Apoptosis Regulator; BCL2; B-cell lymphoma 2; CASP; Caspases; CI; confidence interval; Cyt c; Cytochrome c; DNA; DeoxyriboNucleic Acid; Fas; FAS-associated death domain; FasL; FAS ligand; HWE; Hardy-
RBM17 controls apoptosis and proliferation to promote Glioma progression
Keywords: Glioma; RBM17; Proliferation; FAS; Apoptosis; SPF45; Splicing Factor 45; RBM17; RNA-binding motif protein 17; FAS; Fas cell surface death receptor; GBM; glioblastoma; PARP; poly ADP-ribose polymerase;
Gallotannin derivatives from mango (Mangifera indica L.) suppress adipogenesis and increase thermogenesis in 3T3-L1 adipocytes in part through the AMPK pathway
Keywords: ATCC; American Type Culture Collection; AMPK; AMP-activated protein kinase; BAT; brown adipose tissue; C/EBPα; CCAAT/enhancer binding protein α; CPT1; carnitine palmitoyltransferase I; DCFH-DA; 2â²,7â²-dichlorofluorescein diacetate; DMEM; Dulbecco's
Oral administration of palatinose vs sucrose improves hyperglycemia in normal C57BL/6J mice
Keywords: Palatinose; Hepatic lipogenesis; Cholesterol homeostasis; C57BL/6J mice; Sucrose; ACC; acetyl-CoA carboxylase; ALT; alanine aminotransferase; AST; serum aspartate aminotransferase; AUC; area under the curve; CYP7A1; cholesterol 7 alpha-hydroxylase; FAS; f
Nighttime light exposure enhances Rev-erbα-targeting microRNAs and contributes to hepatic steatosis
Keywords: 6-SML; Urinary 6-sulfatoxymelatonin; ACL; ATP-citrate lyase; ALAN; Artificial Light at Night; BMAL1; Brain and Muscle ARNT-like1; CLOCK; Circadian Locomotor Output Cycles Kaput; Cry; Cryptochrome; DNL; de novo lipogenesis; FAS; Fatty acid synthase; kITT;
Coordinated regulation of hepatic FoxO1, PGC-1α and SREBP-1c facilitates insulin action and resistance
Keywords: aPKC; atypical protein kinase C; ACC; acetyl-CoA carboxylase; ACPD; 2-acetyl-cyclopentane-1,3-dione; AMPK; AMP-activated protein kinase; Akt; protein kinase B; FAS; fatty acid synthase; FoxO1; forkhead homeobox class O1 protein; G6Pase; glucose-6-phosphat
The antipsychotics sulpiride induces fatty liver in rats via phosphorylation of insulin receptor substrate-1 at Serine 307-mediated adipose tissue insulin resistance
Keywords: Adipose tissue; Antipsychotics; Fatty acid; Fatty liver; Insulin resistance; Sulpiride; ACC; acetyl-CoA carboxylase; Adipo-IR; adipose tissue insulin resistance; AUC; area under the curve; ChREBP; carbohydrate-response element-binding protein; D2R; dopami
Pedunculoside, a novel triterpene saponin extracted from Ilex rotunda, ameliorates high-fat diet induced hyperlipidemia in rats
Keywords: Triterpene saponin; Hyperlipidemia; PPAR-α; SREBP-1c; FAS; SCD-1;
LC-MS-based serum fingerprinting reveals significant dysregulation of phospholipids in chronic heart failure
Keywords: ACE-inhibitors; angiotensin-converting-enzyme inhibitors; BNP; B-type natriuretic peptide; BMI; body mass index; CPET; cardiopulmonary exercise test; CRT; cardiac resynchronization therapy; CVD; cardiovascular diseases; FAs; fatty acids; HF; heart failure
Effects of regiolects on the perception of developmental foreign accent syndrome
Keywords: Bilingual; Developmental; Apraxia of speech; Foreign accent syndrome; FAS; Regiolect;
Fish oil and fenofibrate inhibit pancreatic islet hypertrophy, and improve glucose and lipid metabolic dysfuntions with different ways in diabetic KK mice
Keywords: ACC; acetyl-CoA carboxylase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; AOX; acyl-CoA oxidase; DHA; docosahexaenoic acid; EPA; eicosapentaenoic acid; FAS; fatty acid synthase; FF; fenofibrate; FO; fish oil; H&E; haematoxylin eosin; HO
Ranibizumab Plus Panretinal Photocoagulation versus Panretinal Photocoagulation Alone for High-Risk Proliferative Diabetic Retinopathy (PROTEUS Study)
Keywords: AE; adverse event; BCVA; best-corrected visual acuity; DA; disc area; DME; diabetic macular edema; ETDRS; Early Treatment Diabetic Retinopathy Study; FAS; full analysis set; HbA1C; glycated hemoglobin; HR-PDR; high-risk proliferative diabetic retinopathy;
Acute exposure to PBDEs at an environmentally realistic concentration causes abrupt changes in the gut microbiota and host health of zebrafish
Keywords: Gut microbiota; PBDEs; Zebrafish; Intestinal health; Metagenome; AhR; Aryl hydrocarbon receptors; CAT; Catalase; DMSO; Dimethyl sulfoxide; ELISA; Enzyme-linked immunosorbent assay; ER; Estrogen receptors; EROD; Ethoxyresorufin-O-deethylase; FA; Fatty acid
Roles of multiple KASIII homologues of Shewanella oneidensis in initiation of fatty acid synthesis and in cerulenin resistance
Keywords: ACP; acyl carrier protein; CoA; coenzyme A; FAS; fatty acid synthesis/synthetic; KAS; β-ketoacyl-ACP synthase; SCFA; straight-chain fatty acid; BCFA; branched-chain fatty acid; SFA; saturated fatty acid; UFA; unsaturated fatty acid; Fatty acid synthesis;
Behavioral and cellular dopamine D1 and D3 receptor-mediated synergy: Implications for L-DOPA-induced dyskinesia
Keywords: Parkinson's disease; L-DOPA-Induced dyskinesia; Abnormal involuntary movements; D1R-D3R interactions; DA; Dopamine; DOPAC; Dihydroxyphenylacetic acid; PD; Parkinson's disease; LID; L-DOPA-Induced Dyskinesia; D1R; Dopamine D1 Receptor; D2R; Dopamine D2 Rec
CREB element is essential for unfolded protein response (UPR) mediating the Cu-induced changes of hepatic lipogenic metabolism in Chinese yellow catfish (Pelteobagrus fulvidraco)
Keywords: ACC; Acetyl-CoA carboxylase; CREB; cAMP-response element binding protein; ATF6; Activating transcription factor 6; ER; endoplasmic reticulum; ERSE; ER stress response element; FAS; Fatty acid synthase; GRP78/BiP; 78-kDa glucose-regulated protein; IRE1; In
Pharmacological inhibition of DNA methylation attenuates pressure overload-induced cardiac hypertrophy in rats
Keywords: DNMT; DNA methyltransferase; DMC; Differentially methylated cytosine base; EF; Ejection fraction; EDV; End diastolic volume; ESV; End systolic volume; FAS; Fractional area shortening; HW/BW; Heart weight/body weight ratio; LVIDs; Left ventricular inner di
The combined influence of 24âepibrassinolide and 3âindoleacetic acid on growth and accumulation of pigments and fatty acids in the microalgae Scenedesmus quadricauda (CPCC-158)
Keywords: ABA; Abscisic acid; ANOVA; Analysis of Variance; BBM; Bold's Basal Medium; BL; Brassinolide; BRs; Brassinosteroids; CPCC; Canadian Phycological Culture Centre; Drw; dry mass weight; EBL; 24âepibrassinolide; FAs; Fatty Acids; FAMEs; Fatty Acid Methyl Est
Re-evaluating the role of FOXOs in cancer
Keywords: RTK; receptor tyrosine kinase; GF; growth factor; PI3K; Phosphatidylinositol-4,5-bisphosphate 3-kinase; PKB; protein kinase B; AKT; RAC-alpha serine/threonine-protein kinase; FOXO; forkhead box O; GFR; growth factor receptor; PDPK1; Phosphoinositide-depen
Exendin-4, a glucagon-like peptide-1 receptor agonist, reduces hepatic steatosis and endoplasmic reticulum stress by inducing nuclear factor erythroid-derived 2-related factor 2 nuclear translocation
Keywords: Glucagon-like peptide-1; Exendin-4; Nuclear factor erythroid-derived 2-related factor 2; Endoplasmic reticulum stress; Nonalcoholic fatty liver disease; ATF6; Activation transcription factor-6; Bip; Binding immunoglobulin protein; CHOP; C/EBP homologous p
Pharmacological stimulation of p53 with low-dose doxorubicin ameliorates diet-induced nonalcoholic steatosis and steatohepatitis
Keywords: Obesity; Lipid metabolism; Inflammation; AAV8; adeno-associated virus serotype 8; Abcd1; ATP binding cassette subfamily D member 1; Acadl; acyl-CoA deshydrogenase, long-chain; Acadm; acyl-CoA deshydrogenase, medium chain; ACC; acetyl-CoA carboxylase; Acox
Gene network of oil accumulation reveals expression profiles in developing embryos and fatty acid composition in Upland cotton
Keywords: BP; biological process; CC; cellular component; CTAB; cetyltrimethyl ammonium bromide; DAG; diacylglycerol; DEGs; differentially expressed genes; DPA; days post-anthesis; ER; endoplasmic reticulum; FAs; fatty acids; FPKM; fragments per kilobase of exon pe
Onset of Action of the Fixed Combination Intranasal Azelastine-Fluticasone Propionate in an Allergen Exposure Chamber
Keywords: Allergic rhinitis; Azelastine; Environmental exposure chamber; Fluticasone propionate; Loratadine; Onset of action; AEC; Allergen exposure chamber; AR; Allergic rhinitis; EEC; Environmental exposure chamber; ePDAT; electronic Patient Data Acquisition Tabl
A polyphenol-rich prebiotic in combination with a novel probiotic formulation alleviates markers of obesity and diabetes in Drosophila
Keywords: Probiotic; Synbiotic; Gut microbiota; Diabetes; Obesity; TOR; ACC; acetyl CoA-carboxylase; Akt; Protein kinase B; AMPK; 5â²-adenosine monophosphate-activated protein kinase; Bi702255; Bifidobacteria longum spp. infantis NCIMB 702255; BMI; Body mass index
Gangjihwan, a polyherbal composition, inhibits fat accumulation through the modulation of lipogenic transcription factors SREBP1C, PPARγ and C/EBPα
Keywords: ACC1; acetyl-CoA carboxylase 1; C/EBPα; CCAAT/enhancer binding protein alpha; DF; Gangjihwan; DEG; differentially expressed gene; DMEM; Dulbecco's modified Eagle medium; DMSO; dimethylsulfoxide; FAS; fatty acid synthase; HPLC; high performance liquid chr
Trichloroethylene metabolite S-(1,2-dichlorovinyl)-l-cysteine induces lipid peroxidation-associated apoptosis via the intrinsic and extrinsic apoptosis pathways in a first-trimester placental cell line
Keywords: S-(1,2-dichlorovinyl)-l-cysteine [DCVC]; Trichloroethylene [TCE]; Apoptosis; Lipid peroxidation; Extravillous trophoblasts; Placenta; BAK1; BCL2-antagonist/killer 1; BAX; BCL2-associated X protein; BCL-2; B-cell CLL/lymphoma 2; BCL2A1; BCL2-related protei
Galangin's potential as a functional food ingredient
Keywords: Galangin; Propolis; Alpinia officinarum; Functional food ingredient; Polypharmacology; Flavonoid; AChE; acetylcholinesterase; AD; Alzheimer's disease; ADME; Administration, Distribution, Metabolism and Excretion; AHR; airway hyperresponsive; AhR; aryl h